Clinical Trials Directory

Trials / Not Yet Recruiting

Not Yet RecruitingNCT07438405

An Open-label, Rollover Trial to Evaluate the Efficacy and Safety of AMG 732 in Participants With Thyroid Eye Disease

An Open-label, Rollover Study for Participants With Thyroid Eye Disease Previously Enrolled in Amgen-sponsored AMG 732 Studies and Are Primary Proptosis Non-responders or Who Relapsed During the Safety Follow-up

Status
Not Yet Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
30 (estimated)
Sponsor
Amgen · Industry
Sex
All
Age
18 Years – 99 Years
Healthy volunteers
Not accepted

Summary

The main objective of this trial is to assess the efficacy of AMG 732 in participants with thyroid eye disease (TED) who are defined as primary nonresponders or relapsed during the safety follow-up in the parent trial (NCT06401044).

Conditions

Interventions

TypeNameDescription
DRUGAMG 732AMG 732 will be administered SC.

Timeline

Start date
2026-04-14
Primary completion
2028-01-29
Completion
2028-07-14
First posted
2026-02-27
Last updated
2026-04-03

Regulatory

Source: ClinicalTrials.gov record NCT07438405. Inclusion in this directory is not an endorsement.