NCT02461628

Innovative Public-private Partnership to Target Subsidized Antimalarials in the Retail Sector (Aim 2)

Innovative Partnership to Target Antimalarial Subsidies in the Retail Sector

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40,340 (actual)
• Sponsor: Duke University · Academic / Other
• Sex: All
• Age: 1 Year
• Healthy volunteers: Accepted

Summary

The overall objective of this study is to evaluate the public health impact of targeted antimalarials subsidies through scale-up by determining the community-wide effects of targeting an antimalarial subsidy through a partnership between Community Health Volunteers (CHVs) and the private retail sector. The primary hypothesis to be tested is that offering a fixed-price voucher that reduces the cost for artemisinin combination therapy (ACT) purchase in the retail sector conditional on a positive malaria test (targeted subsidy) can improve uptake of testing for malaria and will increase the proportion of fevers tested for malaria before treatment. The study will be carried out in two sub-counties in Kenya with similar malaria burden but different access to health services; the investigators will use a cluster-randomized design to assign community units (CUs) in each sub-county to either an intervention or control arm. CHVs will be trained to use malaria rapid diagnostic tests (RDTs) to diagnose malaria in household members with documented or reported fever; households in intervention CUs will be informed of the intervention and encouraged to contact the CHV for any febrile illness in the home. There are minimal risks associated with receiving an RDT. Households with a positive RDT will be given a serialized voucher that will entitle the holder to purchase a quality assured ACT in the retail sector at a reduced, fixed price. The primary and secondary outcome measures will be compared at baseline and 12 months post-baseline through population-based surveying. The primary aim is to determine whether there is significant difference between the 2 study arms in the proportion of clients with fever who are tested prior to any treatment after adjusting for relevant covariates.

Conditions

• Fever
• Malaria

Interventions

Type	Name	Description
BEHAVIORAL	Malaria RDT & conditional voucher for ACT from retail sector	Trained community health volunteers will offer eligible household members free malaria rapid diagnostic tests and a voucher allowing the purchase of a qualified ACT at a reduced fixed price in the retail sector conditional on a positive test

Timeline

• Start date: 2015-07-01
• Primary completion: 2017-05-26
• Completion: 2017-07-12
• First posted: 2015-06-03
• Last updated: 2019-10-29
• Results posted: 2019-10-29

Locations

1 site across 1 country: Kenya