Clinical Trials Directory

Trials / Conditions / Malaria

Malaria

859 registered clinical trials studyying Malaria29 currently recruiting.

StatusTrialSponsorPhase
Not Yet RecruitingAn Ultra-short Course of Primaquine for the Radical Cure of Vivax Malaria
NCT07468526
Menzies School of Health ResearchPhase 3
Not Yet RecruitingA Clinical Study of Piperaquine, Pyronaridine, and Artesunate Administered in Combination in Healthy Adults
NCT07470424
University of OxfordPhase 1
Not Yet RecruitingIntermittent Preventive Treatment of Malaria in School-age Children to Decrease Community Transmission
NCT07246525
University of California, San FranciscoPhase 4
SuspendedSafety Evaluation of PfSPZ Vaccine in Pregnant Women in Mali (MalVIP1)
NCT05652504
National Institute of Allergy and Infectious Diseases (NIAID)Phase 1
Not Yet RecruitingR21/MM Dosing, Presentations, and Preservatives
NCT07194668
University of OxfordPhase 4
Not Yet RecruitingThis is a Clinical Study to Assess Whether the Combination of SJ733 and Tafenoquine Will be a Safe and Rapidly
NCT07430592
R. Kiplin GuyPhase 2
WithdrawnL9LS-R21 Interaction
NCT07208760
National Institute of Allergy and Infectious Diseases (NIAID)Phase 2
Not Yet RecruitingLong-acting Spatial Emanators / Repellents (LASER)
NCT07387341
Liverpool School of Tropical MedicineN/A
RecruitingRisk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective
NCT07358910
Institut Pasteur du Cambodge
RecruitingOPTImizing Malaria And HIV Treatment in a Shifting Landscape in Africa
NCT06967519
Yale UniversityPhase 4
RecruitingEffectiveness of Malaria Vaccines in Reducing the Risk of Invasive Non-typhoidal Salmonella Disease
NCT07416461
International Vaccine Institute
RecruitingA Study to Assess the Safety and Immunogenicity of a Vaccine Against Malaria in Healthy Children Aged 5-60 Mon
NCT07036159
GlaxoSmithKlinePhase 2
Active Not RecruitingFirst-in-Human PfSPZ-LARC2 Vaccination/CHMI
NCT06735209
National Institute of Allergy and Infectious Diseases (NIAID)Phase 1
RecruitingL9LS in Women of Childbearing Potential in Mali
NCT07060508
National Institute of Allergy and Infectious Diseases (NIAID)Phase 2
Not Yet RecruitingComparing Safety and Protective Efficacy of Vaccine Candidate PfSPZ-CVac and MVA ME-TRAP/ ChAd63 ME-TRAP in Ad
NCT05441410
University Hospital TuebingenPhase 1 / Phase 2
RecruitingMonoclonal Antibodies in Children With Severe Anaemia or Severe Malaria to Prevent Malaria After Hospital Disc
NCT07082205
Liverpool School of Tropical MedicinePhase 3
WithdrawnMaCRA Part B in Nigeria
NCT06805110
PATHN/A
WithdrawnMaCRA Part B in Côte d'Ivoire
NCT06804902
PATHN/A
RecruitingA Study of Oral E1018 in Healthy Adult Participants
NCT06854042
Eisai Inc.Phase 1
CompletedVivax Elimination With Tafenoquine (VET) Study
NCT06575647
Shoklo Malaria Research UnitPhase 4
Not Yet RecruitingHost Immunity, Plasmodium and Pathogens Co-Infections
NCT06769815
Institut PasteurN/A
CompletedKnowledge and Attitude Among Healthcare Workers Towards Malaria Vaccine, Sudan 2025.
NCT07194499
Research and Publication office
RecruitingInduced Blood-Stage Malaria in Healthy Malaria-Naive Adults to Assess the Safety and Infectivity of Plasmodium
NCT06607003
National Institute of Allergy and Infectious Diseases (NIAID)Phase 1
RecruitingFocaL Mass Drug Administration for Vivax Malaria Elimination
NCT05690841
University of California, San FranciscoPhase 3
RecruitingEvaluation of Artesunate in Infants Being Treated for Severe Malaria
NCT06555809
Amivas Inc.
Active Not RecruitingTargeted Antimalarial Drug Administration for Seasonal Migrant Populations in Amhara Region, Ethiopia
NCT06516042
PATHPhase 3
Active Not RecruitingL9LS MAb in Malian Infants
NCT06461026
National Institute of Allergy and Infectious Diseases (NIAID)Phase 1
RecruitingPregnancy Registry in Mali
NCT06468319
National Institute of Allergy and Infectious Diseases (NIAID)
CompletedParasite Clearance and Protection From Infection (PCPI) in Zambia
NCT06166498
London School of Hygiene and Tropical MedicinePhase 3
CompletedParasite Clearance and Protection From Infection (PCPI) in Cameroon
NCT06173206
London School of Hygiene and Tropical MedicinePhase 3
RecruitingEvaluation of the Protective Efficacy of a Spatial Repellent to Reduce Malaria Prevalence in Uganda
NCT06232954
Africa Power LimitedN/A
RecruitingSeasonal R21 Mass Vaccination for Malaria Elimination
NCT06578572
London School of Hygiene and Tropical MedicinePhase 3
UnknownEffectiveness and Cost-effectiveness of Integrated Model for Malaria and Helminth Control
NCT06182176
London School of Hygiene and Tropical MedicineN/A
WithdrawnSpatial Repellents for Malaria Control
NCT06122142
University of Notre DameN/A
Active Not RecruitingOpen-Label Study to Assess Meplazumab in Adult Patients Diagnosed with Plasmodium Falciparum
NCT06040346
Jiangsu Pacific Meinuoke Bio Pharmaceutical Co LtdPhase 2
CompletedA Study to Evaluate Antimalarial Activity and Safety of MK-7602 in Healthy Adults (MK-7602-003)
NCT06294912
Merck Sharp & Dohme LLCPhase 1
RecruitingMalaria Molecular Surveillance in Mozambique (Phase 2)
NCT06529237
Centro de Investigacao em Saude de Manhica
CompletedImproving Knowledge, Attitudes and Practices for Malaria Prevention in the Embera Katio Population
NCT06590597
Universidad de AntioquiaN/A
Active Not RecruitingEvaluation of a Comprehensive School Health Programme in Zambia
NCT06560853
London School of Economics and Political ScienceN/A
SuspendedEvaluation of Vector and Chemoprevention-based Interventions to Reduce Malaria Burden in Urban Daaras of Touba
NCT06225297
PATHPhase 4
RecruitingL-ArGinine to pRevent advErse prEgnancy Outcomes (AGREE)
NCT05934318
Liverpool School of Tropical MedicineN/A
UnknownBuikwe Electronic Community Health Information System Impact Study
NCT06318078
Malaria ConsortiumN/A
CompletedLLIN Evaluation in Uganda Project (LLINEUP3)
NCT05950191
University of California, San FranciscoN/A
CompletedA Clinical Trial to Evaluate the Safety, Efficacy and Immune Responses After Vaccination With an Investigation
NCT06069544
BioNTech SEPhase 1 / Phase 2
Active Not RecruitingNet Transition Initiative: Efficacy of Two Next-generation Nets for Control of Malaria in Cote d'Ivoire
NCT05796193
London School of Hygiene and Tropical MedicineN/A
CompletedDiabetes, Metabolic Syndrome and Risk of Malaria in Cameroon
NCT06278181
Karolinska Institutet
CompletedPan-Malaria Transmission-Blocking Vaccine AnAPN1
NCT05905432
Centre de Recherche Médicale de LambarénéPhase 1
CompletedAssessment of the Malaria Vaccine Candidate SumayaVac-1 in Healthy Adults Aged 18-45 Years Living in a Malaria
NCT05644067
Swiss Tropical & Public Health InstitutePhase 1
Active Not RecruitingA Study to Assess the Safety and Effectiveness of Two Experimental Malaria Vaccines
NCT05978037
University of OxfordPhase 1 / Phase 2
CompletedSafety, Tolerability, Pharmacokinetics and Protective Efficacy of MAM01 in Healthy Adults
NCT05891236
Gates Medical Research InstitutePhase 1
CompletedPiperaquine Granule Formulation Relative Bioavailability and Food Effect Study in Healthy Volunteers.
NCT05930782
Medicines for Malaria VenturePhase 1
Active Not RecruitingPerennial Malaria Chemoprevention (PMC) in Côte D'Ivoire
NCT05856357
London School of Hygiene and Tropical Medicine
Active Not RecruitingPerennial Malaria Chemoprevention (PMC) Effect Study
NCT06155448
Malaria ConsortiumN/A
CompletedStudy of the Plasmodium Vivax Transmission-blocking Vaccine Pvs230D1-EPA/Matrix-M to Assess Safety, Immunogeni
NCT05913973
National Institute of Allergy and Infectious Diseases (NIAID)Phase 1
CompletedPhase 1b MMV367 PK/PD and Safety in Healthy Adult Volunteers Experimentally Infected With Blood Stage P. Falci
NCT05979207
Medicines for Malaria VenturePhase 1
UnknownChemoprevention Efficacy Study Nigeria
NCT05979896
Malaria ConsortiumPhase 4
Active Not RecruitingPerennial Malaria Chemoprevention (PMC) in Cameroon
NCT05889052
London School of Hygiene and Tropical Medicine
CompletedCHILD (Child Health and Infection With Low Density) Malaria
NCT05567016
University of California, San FranciscoN/A
UnknownInnovative Intermittent Preventive Treatment Approaches to Reduce Malaria Burden in School-age Children in Bur
NCT05946642
Malaria ConsortiumPhase 3
CompletedUnderstanding and Maximizing the Community Impact of Antimalarial Treatment (INDIE-SMC)
NCT05878366
London School of Hygiene and Tropical MedicineN/A
WithdrawnUse of Malaria Rapid Diagnostic Tests as a Decision Aid for the Management of Fever by International Travelers
NCT02900079
Institute of Tropical Medicine, Belgium
RecruitingACT vs CQ With Tafenoquine for P. Vivax Mono-infection
NCT05788094
Shoklo Malaria Research UnitPhase 4
Active Not RecruitingA Study to Compare Two Dosing Regimens for a New Malaria Vaccine
NCT06141057
University of OxfordPhase 1
CompletedField Evaluations of Innovative Tools for Vector-borne Disease Control in Conflict-affected Communities
NCT06179732
The Mentor InitiativePhase 3
CompletedImpact of Differential and Systematic Diagnosis of Dengue, Chikungunya and Malaria on Patient Management and A
NCT06257810
BioMérieuxN/A
CompletedL9LS MAb in Malian Adults
NCT05816330
National Institute of Allergy and Infectious Diseases (NIAID)Phase 2
CompletedComparative Study of Thrombocytopenia in Plasmodium Vivax and Falciparum Malaria
NCT07122232
Rafiullah Hotak
Active Not RecruitingEaveTubes for Vector Control
NCT05736679
University of Notre DameN/A
CompletedClinical Validation of Novel Malaria Diagnostic Tools for POC Point-of-Care Testing
NCT06225700
Foundation for Innovative New Diagnostics, Switzerland
CompletedEfficacy of Only IV Artesunate Versus IV Artesunate Plus IV Quinine in the Treatment of Severe Malaria in Chil
NCT06472258
RESnTEC, Institute of ResearchN/A
CompletedAssessment of Safety and Immunogenicity of R21/Matrix-M™ in African Children Living With HIV
NCT05385510
University of OxfordPhase 1
CompletedTherapeutic Efficacy of Chloroquine Plus Primaquine in the Treatment of Uncomplicated Plasmodium Vivax
NCT06044805
Dinka DugassaPhase 4
CompletedSafety and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria
NCT05581641
BioNTech SEPhase 1
TerminatedA Phase 1 Trial of PfSPZ Vaccine in Healthy Adults to Determine Safety, Tolerability and Efficacy Against Hete
NCT05604521
Sanaria Inc.Phase 1
TerminatedA Study of the Plasmodium Falciparum Malaria Vaccine Candidate Pfs48/45 in Matrix-M Adjuvant in the UK
NCT05400746
University of OxfordEARLY_Phase 1
UnknownAfrica Ready Malaria Screening
NCT06153862
University of GhanaN/A
CompletedAnti-malaria MAb in Kenyan Children
NCT05400655
National Institute of Allergy and Infectious Diseases (NIAID)Phase 2
Active Not RecruitingSulfadoxine-pyrimethamine Plus Dihydroartemisinin-piperaquine for Intermittent Preventive Treatment in Pregnan
NCT05426434
Menzies School of Health ResearchPhase 3
CompletedEfficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Treatment of Plasmodium Falciparum Malaria
NCT06300970
Centers for Disease Control and PreventionPhase 4
UnknownIvermectin-artemisinin Combination Therapy for Eradication of Malaria
NCT05605925
Makerere UniversityPhase 4
Active Not RecruitingTrajectories and Mechanisms of Recovery From Malaria: An Observational Study
NCT05149157
Imperial College London
UnknownEffectiveness, Feasibility and Acceptability of Seasonal Malaria Chemoprevention in Aweil South County in Sout
NCT05471544
Malaria ConsortiumPhase 3
CompletedA Study of Blood-stage Controlled Human Plasmodium Falciparum Malaria Infection in Tanzania
NCT04788862
University of OxfordN/A
UnknownChemoprevention Efficacy Study in Burkina Faso
NCT05478954
Malaria ConsortiumPhase 4
UnknownEvaluating the Clinical Performance and Usability of Novel Malaria RDTs in Brazil
NCT05317117
PATHN/A
CompletedHealth Education by Buddhist Monks to Promote Malaria Knowledge and Preventive Practices in Rural Myanmar
NCT06386367
Myanmar Health Network OrganizationN/A
CompletedAbbott NxTekTM Malaria RDT WHO Prequalification Study
NCT05444790
Foundation for Innovative New Diagnostics, Switzerland
UnknownFeasibility and Safety of Combining Anti-malarial With Deworming Drugs in African Children
NCT05354258
London School of Hygiene and Tropical MedicineN/A
RecruitingObservational Study of the Safety of Intravenous Artesunate Treatment of Pregnant Women and Their Infants
NCT05285735
Amivas Inc.
CompletedPermethrin-treated Baby-wraps for the Prevention of Malaria in Children
NCT05391230
University of North Carolina, Chapel HillN/A
UnknownEffectiveness and Chemoprevention Efficacy of Implementing Seasonal Malaria Chemoprevention in Karamoja Region
NCT05323721
Malaria ConsortiumPhase 4
CompletedPerformance Evaluation of Malaria Plus Rapid Diagnostic Tests (RDTs) for the Detection of Plasmodium Infection
NCT05286359
Abbott Rapid DxN/A
CompletedAssessment of Safety and Immunogenicity of a Single Vial Presentation of R21/Matrix-M and Co-Administration Wi
NCT05155579
University of OxfordPhase 1
CompletedSafety, Tolerability, Immunogenicity and Protective Efficacy of PfSPZ Vaccine and PfSPZ-CVac in Indonesian Adu
NCT03503058
Sanaria Inc.Phase 2
UnknownPlasmodium Vivax Among Duffy Negative Population in Cameroon.
NCT05058885
University of Dschang
UnknownERASE - Impact of COVID-19 on Malaria Control
NCT05348746
Doctors with Africa - CUAMM
CompletedDrug-drug Interaction Study of Ganaplacide and Lumefantrine With Efavirenz
NCT05330273
Novartis PharmaceuticalsPhase 1
UnknownEfficacy and Safety of Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine in Cameroon
NCT05340153
University of Yaounde 1Phase 4
CompletedPyronaridine in Healthy Adult Participants Infected With Blood Stage Malaria
NCT05287893
Medicines for Malaria VenturePhase 1
CompletedPfSPZ Vaccine Trial in Malian Children
NCT04940130
Sanaria Inc.Phase 2
CompletedMMV533 Plasmodium Falciparum Volunteer Infection Study
NCT05205941
Medicines for Malaria VenturePhase 1
CompletedAnti-malaria MAb in Malian Children
NCT05304611
National Institute of Allergy and Infectious Diseases (NIAID)Phase 2
CompletedBroad One Health Endectocide-based Malaria Intervention in Africa (BOHEMIA)
NCT04966702
Barcelona Institute for Global HealthPhase 3
CompletedIn Vivo Efficacy of Artemether-Lumefantrine, Amodiaquine-Artesunate, Dihydroartemisinin-Piperaquine, and Piron
NCT05343312
Centro de Investigacao em Saude de ManhicaPhase 4
CompletedDrug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Met
NCT05236530
Novartis PharmaceuticalsPhase 1
CompletedCommunity Dynamics of Malaria Transmission in Humans and Mosquitoes at Maferinyah Sub-Prefecture, Guinea
NCT04969913
National Institute of Allergy and Infectious Diseases (NIAID)
CompletedEvaluating ATSBs for Malaria Reduction in Kenya
NCT05219565
Liverpool School of Tropical MedicineN/A
CompletedBlood-Stage Plasmodium Vivax Cell Bank
NCT05095272
National Institute of Allergy and Infectious Diseases (NIAID)Phase 1
CompletedMULTIple Doses of IPTi Proposal: a Lifesaving High Yield Intervention
NCT05085340
Barcelona Institute for Global Health
Active Not RecruitingModifying Immunity in Children With DihydROartemisinin-Piperaquine (MIC-DroP)
NCT04978272
Grant Dorsey, M.D, Ph.D.Phase 3
UnknownEffectiveness of Seasonal Malaria Chemoprevention in Nampula Province, Mozambique: Type Two Hybrid Implementat
NCT05186363
Malaria ConsortiumPhase 4
RecruitingStar Homes Project 2
NCT04529434
University of OxfordN/A
CompletedRapiGEN BIOCREDIT Malaria Ag RDTs WHO Prequalification Study
NCT05085301
Foundation for Innovative New Diagnostics, Switzerland
UnknownMalaria Control : Improving Access to Prevention, Diagnostic and Care for Vulnerable Rural Communities
NCT05535465
Institut de Recherche pour le DeveloppementN/A
CompletedDrug-drug Interaction Study of Ganaplacide and Lumefantrine With Itraconazole
NCT05084651
Novartis PharmaceuticalsPhase 1
CompletedMonitoring Pregnant Women for Antimalarial Drug Resistance
NCT05072613
University of Oxford
CompletedShort Course Radical Cure of P. Vivax Malaria in Nepal
NCT04079621
Menzies School of Health ResearchPhase 4
RecruitingStrengthening the Evidence for Policy on the RTS,S/AS01 Malaria Vaccine
NCT05041556
Kintampo Health Research Centre, Ghana
CompletedPlasmodium Falciparum Genomic Intelligence in Mozambique
NCT05306067
Centro de Investigacao em Saude de Manhica
Active Not RecruitingCommunity Dynamics of Malaria Transmission in Humans and Mosquitoes in Fleh-la and Marshansue, Salala District
NCT04704674
National Institute of Allergy and Infectious Diseases (NIAID)
CompletedSafety, Tolerability and Efficacy of PfSPZ Vaccine Against Heterologous CHMI in US Malaria naïve Adults
NCT04966871
Sanaria Inc.Phase 1
CompletedTrial to Evaluate L9LS in Healthy Adults
NCT05019729
National Institute of Allergy and Infectious Diseases (NIAID)Phase 1
CompletedA Study Of Zy-19489 Administered Via Oral Route To Investigate The Safety, Tolerability And Pharmacokinetics I
NCT05206201
Zydus Lifesciences LimitedPhase 1
SuspendedBaromètre Santé Adulte 2021-2022
NCT05218304
Agence Sanitaire et Sociale de Nouvelle CalédonieN/A
CompletedSpatial Repellents for Vector Control
NCT04795648
University of Notre DameN/A
CompletedBoosting the Impact of SMC Through Simultaneous Screening and Treatment of Roommates
NCT04816461
Institut de Recherche en Sciences de la Sante, Burkina FasoPhase 4
CompletedImpact of Malaria Mass Drug Administration on Malaria Prevalence in Under 15 Children and Pregnant Women
NCT07358767
Noguchi Memorial Institute for Medical ResearchN/A
CompletedMolecular Basis of Erythrocyte Invasion by Plasmodium Vivax Into Duffy-Negative Erythrocytes in Mali
NCT03304691
National Institute of Allergy and Infectious Diseases (NIAID)
CompletedMass Drug Administration of Dihydroartemisinin-piperaquine + Single Low-dose Primaquine to Accelerate Toward E
NCT04864444
University of California, San FranciscoN/A
CompletedLAMP Detection of Malaria in PREGnancy (LAMPREG) Trial
NCT03754322
University of CalgaryN/A
CompletedMalaria Transmission in Humans and Mosquitoes at the Area of Sabou, Burkina Faso
NCT04650815
National Institute of Allergy and Infectious Diseases (NIAID)
CompletedSafety and Efficacy of Maytenus Senegalensis for the Treatment of Uncomplicated Malaria
NCT04944966
Ifakara Health InstitutePhase 2
UnknownEvaluation of Three Artemisinin-based Combinations for the Treatment of Uncomplicated Malaria in Childreen in
NCT04778813
Centre national de recherche et de formation sur le paludismePhase 4
UnknownPerformance Evaluation of Malaria Plus RDTs
NCT03960632
Foundation for Innovative New Diagnostics, Switzerland
CompletedSafety and Efficacy of R0.6C Vaccine
NCT04862416
Radboud University Medical CenterPhase 1
UnknownValidation of a CDSA Strategy to Reduce Antibiotic Prescription in Senegal
NCT05050825
Foundation for Innovative New Diagnostics, SwitzerlandN/A
Active Not RecruitingR21/Matrix-M in African Children Against Clinical Malaria
NCT04704830
University of OxfordPhase 3
Active Not RecruitingEvaluation of IR3535 as a Spatial Repellent for Malaria Control.
NCT04419766
Universidade Nova de LisboaN/A
CompletedProactive Community Case Management for Malaria in Zambia
NCT04839900
PATHN/A
CompletedDihydroartemisinin-Piperaquine or Sulphadoxine-Pyrimethamine for the Chemoprevention of Malaria in Sickle Cell
NCT04844099
Liverpool School of Tropical MedicinePhase 3
CompletedMalaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: TESTsmART Aim 2 - Ni
NCT04428385
Duke UniversityN/A
CompletedClinical Investigation Study to Evaluate the Consistency and Reproducibility of Two Consecutive Mosquito Feedi
NCT04666350
PATH
CompletedSpatial Repellents for the Prevention of Malaria in Kenya
NCT04766879
University of Notre DameN/A
CompletedSafety and Efficacy of CIS43LS Anti-malaria mAb in Mali
NCT04329104
National Institute of Allergy and Infectious Diseases (NIAID)Phase 2
UnknownInfection Tracking in Travellers. The Project Aims to Identify Profiles of Travel-associated Illness and to Fo
NCT04672577
Patricia Schlagenhauf
UnknownUganda Housing Modification Study
NCT04622241
Infectious Diseases Research Collaboration, UgandaN/A
UnknownHousehold-level Impact of IPT of Malaria in Schoolchildren
NCT04660110
Makerere UniversityPhase 3
CompletedCharacterizing Humoral Immune Response to Mosquito Bites
NCT04478370
University of OxfordN/A
UnknownOptimizing Malaria Treatment for HIV-Malaria Co-infected Individuals
NCT04708496
Makerere UniversityPhase 4
UnknownMobile Point of Care Diagnostic Testing for Ebola Virus Disease in DRC
NCT04235361
University of Stirling
CompletedMalaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: TESTsmART Aim 2 - Ke
NCT04428307
Duke UniversityN/A
CompletedMalaria as a Risk Factor for COVID-19 in Western Kenya and Burkina Faso
NCT04695197
Liverpool School of Tropical MedicinePhase 3
CompletedAn MRI Ancillary Study of a Malaria Fever Investigation
NCT05746819
University of Rochester
UnknownEffectiveness of a Community-delivered Integrated Malaria Elimination (CIME) Model in Myanmar
NCT04695886
Macfarlane Burnet Institute for Medical Research and Public Health LtdN/A
CompletedOptimal Chemopreventive Regimens to Prevent Malaria and Improve Birth Outcomes in Uganda
NCT04336189
Grant Dorsey, M.D, Ph.D.Phase 3
CompletedAntenatal Care as a Platform for Malaria Surveillance: Utilizing Community Prevalence Measures From the New Ne
NCT04724161
PATH
UnknownAttractive Targeted Sugar Bait Phase III Trial in Zambia
NCT04800055
PATHN/A
CompletedSafety and Efficacy of Recommended Antimalarial in the Democratic Republic of the Congo
NCT04618523
Ministry of Public Health, Democratic Republic of the CongoPhase 4
CompletedLLIN Evaluation in Uganda Project
NCT04566510
University of California, San FranciscoN/A
CompletedInnovation Platform
NCT04558528
Foundation for Innovative New Diagnostics, Switzerland
CompletedAntenatal Care as a Platform for Malaria Surveillance: Utilizing Community Prevalence Measures From the New Ne
NCT04545905
PATH
CompletedAssess Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Profile of Ruxolitinib With Artemether-lumefa
NCT04456634
Medicines for Malaria VenturePhase 1
CompletedBaseline Cohort Malaria Morbidity Study
NCT04601714
Groupe de Recherche Action en Sante
CompletedPerceptions, Representations and Experiences of Malaria Prophylaxis in Patients Born in Endemic Areas and Livi
NCT04494854
Centre Hospitalier Intercommunal Creteil
CompletedEfficacy of Antimalarial Drugs Used for the Treatment of Uncomplicated Malaria, Plasmodium Falciparum, at the
NCT05070520
Programme National de Lutte contre le Paludisme, NigerPhase 4
CompletedGut and Azithromycin Mechanisms in Infants and Children II
NCT04315272
University of California, San FranciscoPhase 4
CompletedEstimating the Malaria Prevention Impact of New Nets: Observational Analyses to Evaluate the Evidence Generate
NCT04716387
PATH
CompletedA Phase 1 Study to Assess the Safety, Tolerability, and Pharmacokinetic Profile of a Single Doses of MMV533.
NCT04323306
Medicines for Malaria VenturePhase 1
CompletedStudy to Assess Safety, Tolerability and Phamacokinetics of KAE609 Administered Intravenously in Healthy Subje
NCT04321252
Novartis PharmaceuticalsPhase 1
CompletedEvaluation of the Implementation and Effectiveness of Intermittent Preventive Treatment for Malaria Using Dihy
NCT04245033
National Institute for Medical Research, TanzaniaPhase 4
UnknownAssessment of a Combined Strategy of SMC + Nutrients Supplementation to Tackle Malaria and Malnutrition
NCT04238845
Institut de Recherche en Sciences de la Sante, Burkina FasoN/A
CompletedMalaria Prevalence Around Maferinyah, Guinea
NCT04105855
National Institute of Allergy and Infectious Diseases (NIAID)
CompletedDihydroartemisinin-piperaquine for Seasonal Malaria Chemoprophylaxis in Tanzania
NCT05874869
Richard MwaisweloN/A
CompletedEfficacy of Two Dual Active Ingredient Long Lasting Insecticidal Nets for Control of Malaria Transmitted by Py
NCT03931473
London School of Hygiene and Tropical MedicineN/A
CompletedStudy to Assess Efficacy of Artemether-lumefantrine Prophylaxis Against Forest Malaria in Cambodia (PAL_Cambod
NCT04041973
University of OxfordN/A
CompletedEstimating the Malaria Prevention Impact of New Nets: Observational Analyses to Evaluate the Evidence Generate
NCT04230161
PATH
CompletedAutomated Microscopy Evaluation Study
NCT04558515
Foundation for Innovative New Diagnostics, Switzerland
UnknownEvaluation of Targeted Mass Drug Administration for Malaria in Ethiopia
NCT04241705
Armauer Hansen Research Institute, EthiopiaN/A
CompletedTrial to Evaluate CIS43LS in Healthy Adults
NCT04206332
National Institute of Allergy and Infectious Diseases (NIAID)Phase 1
UnknownBiomarkers of P. Vivax Relapse
NCT04228315
Armed Forces Research Institute of Medical Sciences, ThailandN/A
TerminatedAssessing the Impact of Group Antenatal Care on IPTp Uptake in Tanzania
NCT04148690
Centers for Disease Control and PreventionN/A
CompletedMalaria High-Risk Populations in Namibia
NCT04094727
University of California, San FranciscoPhase 4
CompletedGetting Malaria "Off the Back" of Women and Children in Western Uganda
NCT04102592
University of North Carolina, Chapel HillN/A
CompletedPlasmodium and Other Parasites in Pregnant Women and Children Around Margibi and Montserrado Counties, Liberia
NCT03719599
National Institute of Allergy and Infectious Diseases (NIAID)
RecruitingCollection of Human Biospecimens for Basic and Clinical Research Into Globin Variants
NCT03937817
National Institute of Allergy and Infectious Diseases (NIAID)
CompletedImproving Maternal heAlth by Reducing Malaria in African HIV Women
NCT03671109
Barcelona Institute for Global HealthPhase 3
WithdrawnA Study to Assess the Safety and Efficacy of 5-aminolevulinic Acid Hydrochloride (5-ALA HCl) and Sodium Ferrou
NCT04020653
Neopharma Japan Co., Ltd.Phase 2
CompletedOptimizing Benefits While Reducing Risks of Iron in Malaria-endemic Areas
NCT03897673
University of MinnesotaN/A
CompletedReducing the Risk of P. Vivax After Falciparum Infections in Co-endemic Areas
NCT03916003
Menzies School of Health ResearchPhase 4
UnknownP. Falciparum Infection Dynamics and Transmission to Inform Elimination
NCT04053907
London School of Hygiene and Tropical MedicineN/A
CompletedEffectiveness of Malaria Camps as Part of the Odisha State Malaria Elimination Drive
NCT03963869
NYU Langone HealthN/A
CompletedRepeat Ivermectin Mass Drug Administrations for MALaria Control II
NCT03967054
Brian FoyPhase 3
CompletedEstimating the Malaria Prevention Impact of New Nets: Observational Analyses to Evaluate the Evidence Generate
NCT04157894
PATH
CompletedSafety, Immunogenicity, and Protective Efficacy of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites
NCT03989102
National Institute of Allergy and Infectious Diseases (NIAID)Phase 2
Active Not RecruitingEfficacy of Focal Primaquine Mass Administration for Eliminating Plasmodium Vivax Malaria in Northern Myanmar
NCT06392152
Pyae Linn AungN/A
CompletedVAC 072-An Efficacy Study of R21/MM in Different Dose Schedules
NCT03970993
University of OxfordPhase 1 / Phase 2
CompletedSingle Low-dose Primaquine Efficacy and Safety.
NCT03352843
Tropical Pesticides Research Institute, TanzaniaPhase 4
CompletedSanaria PfSPZ Challenge With Pyrimethamine or Chloroquine Chemoprophylaxis Vaccination (PfSPZ-CVac Approach):
NCT03952650
National Institute of Allergy and Infectious Diseases (NIAID)Phase 1 / Phase 2
CompletedPfs230D1M-EPA/AS01 Vaccine, a Transmission Blocking Vaccine Against Plasmodium Falciparum, in an Age De-Escala
NCT03917654
National Institute of Allergy and Infectious Diseases (NIAID)Phase 2
UnknownInfections in Migrants in Sweden - the Importance of Malaria and Other Parasitic Infections
NCT05086887
Region Stockholm
UnknownMalaria Birth Cohort (MBC) in Agogo, Ghana
NCT04050566
Bernhard Nocht Institute for Tropical Medicine
CompletedDetermine the Tolerability and Safety of Atovaquone-proguanil (ATV-PG) Co-administered With Amodiaquine (AQ)
NCT04002687
Medicines for Malaria VenturePhase 1
CompletedMalaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: the TESTsmART Trial
NCT03810014
Duke UniversityN/A
CompletedA Study Assessing the Safety, Efficacy, and Impact of GlaxoSmithKline Biologicals' RTS, S/AS01E Malaria Vaccin
NCT03855995
GlaxoSmithKline
CompletedDiagnostic and Prognostic Biomarkers for Childhood Bacterial Pneumonia
NCT03996967
Boston University
CompletedA Study to Evaluate the Efficacy, Immunogenicity and Safety in a Sporozoite Challenge Model of a Fractional Bo
NCT03824236
GlaxoSmithKlinePhase 2
CompletedEfficacy of Three Novel Bi-treated Long Lasting Insecticidal Nets
NCT03554616
London School of Hygiene and Tropical MedicineN/A
CompletedCombination Momordica Charantia Extract and Primaquine Againts Plasmodium Falciparum Uncomplicated and Plasmod
NCT06036030
Syamsudin Abdillah,Ph.D, Pharm DPhase 2
CompletedAggressive Antipyretics for Fever Reduction in CNS Malaria
NCT03399318
University of RochesterPhase 2
CompletedStudy to Assess the Vaccine Efficacy Against Malaria Infection, in Children Immunized With the Primary and Yea
NCT03281291
GlaxoSmithKline
CompletedSafety, Tolerability and Chemoprotective Activity of P218 in PfSPZ Challenge Model
NCT03707041
Medicines for Malaria VenturePhase 1
CompletedFeasibility, Acceptability and Costs of a Multiple First-lines Artemisinin-based Combination Therapies
NCT04265573
Groupe de Recherche Action en Sante
CompletedVAC063C: A Study to Assess Repeat Blood-stage P. Falciparum Infection
NCT03906474
University of OxfordN/A
CompletedAn Efficacy Study of IV Boosting With ChAd63/MVA ME-TRAP
NCT03707353
University of OxfordPhase 1 / Phase 2
WithdrawnChloroquine (CQ) and Azithromycin (AZ) Combination for Malaria Prophylaxis
NCT03278808
U.S. Army Medical Research and Development CommandPhase 2
CompletedTrial to Evaluate the Safety, Immunogenicity, and Efficacy of Malaria Infection in Malaria Naïve Adults
NCT03341754
U.S. Army Medical Research and Development CommandPhase 1
CompletedDefining Skin Immunity of a Bite of Key Insect Vectors in Humans
NCT03641339
National Institute of Allergy and Infectious Diseases (NIAID)N/A
UnknownMonthly Versus Two Doses of Ante-Natal Intermittent Preventive Treatment With Sulphadoxine-Pyrimethamine
NCT03599596
University College Hospital, IbadanPhase 1
WithdrawnDried Leaf Artemisia (DLA) Compared to Artemisinin Combination Therapy (ACT) vs Malaria
NCT03199755
Worcester Polytechnic InstitutePhase 2
CompletedMetabolism and Pharmacokinetics of Primaquine Enantiomers in Human Volunteers Receiving a Seven Day Dose Regim
NCT03934450
University of Mississippi, OxfordPhase 1
CompletedMass Drug Administration of Ivermectin and Dihydroartemisinin-piperaquine as an Additional Intervention for Ma
NCT03576313
London School of Hygiene and Tropical MedicinePhase 3
CompletedStudy Assessing Pharmacokinetics and Bioavailability of Three Novel Triazine Compounds
NCT03436160
U.S. Army Medical Research and Development CommandEARLY_Phase 1
CompletedP. Falciparum Infection Dynamics and Transmission to Inform Elimination (INDIE-1a)
NCT03705624
London School of Hygiene and Tropical MedicineN/A
UnknownMalaria in Strasbourg University Hospital
NCT03594084
University Hospital, Strasbourg, France
TerminatedSafety and Pharmacokinetics Study of DM1157 to Treat Malaria
NCT03490162
National Institute of Allergy and Infectious Diseases (NIAID)Phase 1
CompletedRegimen Optimization Trial of PfSPZ Vaccine in Equatorial Guinea
NCT03590340
Sanaria Inc.Phase 1
CompletedDynamics of Subclinical Malaria: Preliminary Study
NCT03483571
Duke University
CompletedEvaluation of a Digital Microscope for Malaria
NCT03512678
University of Oxford
CompletedCommunity Access to Rectal Artesunate for Malaria
NCT03568344
Swiss Tropical & Public Health Institute
CompletedSafety, Tolerability and Protective Efficacy of PfSPZ Vaccine in Gabonese Children
NCT03521973
Sanaria Inc.Phase 2
CompletedMonitoring of Perfusion in Sepsis and Malaria
NCT03641534
University of Oxford
CompletedSafety, Immunogenicity, and Protective Efficacy of Two Regimens of Radiation Attenuated Plasmodium Falciparum
NCT03510481
National Institute of Allergy and Infectious Diseases (NIAID)Phase 1
UnknownLiberia National Community Health Assistant (NCHA) Program and Under-five Mortality
NCT05123378
Last Mile HealthN/A
CompletedSafety, Tolerability and Antimalarial Activity of Single Doses of OZ439 and PQP
NCT03542149
Medicines for Malaria VenturePhase 1
CompletedEvaluation of a New Malaria Control Strategy Amongst Gold Miners Working Illegally in French Guiana (Malakit)
NCT03695770
Centre Hospitalier de CayenneN/A
UnknownTransmission Dynamics of Residual and Re-emerging Malaria in the Amazon: Defining a Roadmap to Malaria Elimina
NCT03689036
Oswaldo Cruz Foundation
CompletedImproving PRegnancy Outcomes With Intermittent preVEntive Treatment in Africa
NCT03208179
Liverpool School of Tropical MedicinePhase 3
CompletedSusceptibility of Gambian Adults to PfSPZ-Challenge Infection in the Controlled Human Malaria Infection Model
NCT03496454
London School of Hygiene and Tropical MedicineN/A
CompletedIn Vivo Efficacy of Artemether-lumefantrine and Amodiaquine-artesunate in Mozambican Children (MEFI_III)
NCT04370977
Centro de Investigacao em Saude de ManhicaPhase 4
CompletedStudy to Evaluate Safety, Immunogenicity and Efficacy of PfSPZ Vaccine in HIV Negative and HIV Positive Tanzan
NCT03420053
Sanaria Inc.Phase 1
CompletedCommunity Dynamics of Malaria Transmission and Mosquito Feeding in Bancoumana, Mali
NCT03304704
National Institute of Allergy and Infectious Diseases (NIAID)
CompletedPreventing Mental Health Problems After Childhood Severe Malaria
NCT03432039
Makerere UniversityN/A
CompletedSafety of KAE609 in Adults With Uncomplicated Plasmodium Falciparum Malaria.
NCT03334747
Novartis PharmaceuticalsPhase 2
UnknownField Efficacy Of Insecticide Treated Uniforms And Skin Repellents for Malaria Prevention
NCT02938975
Ifakara Health InstitutePhase 3
TerminatedMMV390048 POC in Patients With P. Vivax and P. Falciparum Malaria
NCT02880241
Medicines for Malaria VenturePhase 2
CompletedEfficacy, Safety and Immunogenicity Study of GSK Biologicals' Candidate Malaria Vaccine (SB257049) Evaluating
NCT03276962
GlaxoSmithKlinePhase 2
CompletedPrevalence Survey of Antimalarial Drug Resistance Markers
NCT03217851
University of Oxford
CompletedOptimizing Hydroxyurea Therapy in Children With SCA In Malaria Endemic Areas
NCT03128515
Indiana UniversityPhase 3
CompletedA Safety and Efficacy Study of ChAdOx1 LS2 and MVA LS2
NCT03203421
University of OxfordPhase 1 / Phase 2
CompletedImpact of Scaling up Mass Testing, Treatment and Tracking on Malaria Prevalence Among Children
NCT04167566
Noguchi Memorial Institute for Medical ResearchN/A
CompletedDose Escalation PfSPZ-CVac
NCT03083847
National Institute of Allergy and Infectious Diseases (NIAID)Phase 1
CompletedEfficacy, Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Evaluating Different D
NCT03162614
GlaxoSmithKlinePhase 2
CompletedSafety and Protective Efficacy of Genetically Attenuated PfSPZ-GA1 Vaccine in Healthy Dutch Volunteers
NCT03163121
Sanaria Inc.Phase 1
CompletedImmunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Given at 6, 7.5 and 9 Months of
NCT02699099
GlaxoSmithKlinePhase 3
CompletedMetabolism and Pharmacokinetics of Primaquine Enantiomers in Human Volunteers, Study 1
NCT02898779
University of Mississippi, OxfordPhase 1
CompletedA Study to Assess the Safety and Immunogenicity of a Candidate Malaria Vaccine Using Novel Routes of Administr
NCT03084289
University of OxfordPhase 1
CompletedEfficacy and Safety of Artemisinin-based Combination Treatments in the Democratic Republic of the Congo
NCT02940756
Ministry of Public Health, Democratic Republic of the CongoPhase 4
CompletedAbsolute BA and OZ439 PK Effect of Different OZ439 Dose Volumes and Cobicistat Co-administration Study
NCT04069221
Medicines for Malaria VenturePhase 1
CompletedImpact of Malaria on Pregnant Women in Ouelessebougou, Mali
NCT02974608
National Institute of Allergy and Infectious Diseases (NIAID)
UnknownMobilization at the Level of Schools on the Behavioral Change in Favor of the Fight Against Malaria in Mbandjo
NCT04570241
Cameroon Coalition Against Malaria (CCAM)N/A
CompletedEfficacy and Safety of IPTp-DP Versus IPTp-SP in Malawi
NCT03009526
Kamuzu University of Health SciencesPhase 3
CompletedCost-effectiveness Evaluation of Vector Control Strategies in Mozambique
NCT02910934
PATHN/A
CompletedProactive Community Case Management (Pro-CCM) in Rural Madagascar
NCT05223933
Institut Pasteur de MadagascarN/A
RecruitingScreening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human
NCT02639299
National Institute of Allergy and Infectious Diseases (NIAID)
CompletedSafety and Protective Efficacy of IV Immunization With Cryopreserved PfSPZ Under A/P Chemoprophylaxis
NCT02858817
University Hospital TuebingenPhase 1
CompletedField Evaluation of a Device for Automated Malaria Microscopy (Autoscope Version 2)
NCT02932072
University of Oxford
CompletedRHOST-cRCT, Reactive Household-based Self-administered Treatment Against Residual Malaria Transmission
NCT02878200
London School of Hygiene and Tropical MedicineN/A
CompletedSafety, Tolerability and Immunogenicity of PfSPZ Vaccine in an Age De-escalation Trial in Equatorial Guinea.
NCT02859350
Sanaria Inc.Phase 1
CompletedPhysiologically-based Pharmacokinetic Modeling of Ivermectin in Healthy Human Volunteers
NCT02963324
University Hospital, Basel, SwitzerlandPhase 1
CompletedSafety and Immunogenicity of Pfs25M-EPA/AS01 and Pfs230D1M-EPA/AS01 Vaccines, Transmission Blocking Vaccines A
NCT02942277
National Institute of Allergy and Infectious Diseases (NIAID)Phase 1
CompletedA Challenge Study to Assess the Safety, Immunogenicity and Efficacy of a Malaria Vaccine Candidate
NCT02927145
University of OxfordPhase 1 / Phase 2
CompletedEffect of Paracetamol on Renal Function in Plasmodium Knowlesi Malaria
NCT03056391
Menzies School of Health ResearchPhase 3
CompletedAssessing Model Parameters for Applying the Retinol Isotope Dilution (RID) Method
NCT02996513
Wageningen UniversityN/A
CompletedCardiac Safety of Dihydroartemisinin-Piperaquine Amongst Pregnant Women in Tanzania
NCT02909712
London School of Hygiene and Tropical MedicinePhase 2
CompletedPrevention of Malaria in HIV-uninfected Pregnant Women and Infants
NCT02793622
University of California, San FranciscoPhase 3
WithdrawnDiagnostic Utility of Volatile Organic Compounds in Human Breath for Acute Clinical Malaria in Ethiopia
NCT02793414
Menzies School of Health Research
WithdrawnA Trial on Supervised Primaquine Use in Ethiopia
NCT02793388
Menzies School of Health ResearchPhase 4
CompletedSequential Optimization of Dose and Schedule of PfSPZ Vaccine
NCT02704533
Sanaria Inc.Phase 1
CompletedA Study to Assess the Safety and Immunogenicity of the Malaria Vaccine, R21, With Matrix-M1 Adjuvant
NCT02925403
University of OxfordPhase 1 / Phase 2
CompletedA FIH Study to Investigate the Safety, Tolerability and PK of P218
NCT02885506
Medicines for Malaria VenturePhase 1
CompletedEarly Life Cohort in Papua Indonesia (ELIPI Study)
NCT02793336
Menzies School of Health Research
CompletedA Safety and Efficacy Study of R21 +/- ChAd63/MVA ME-TRAP
NCT02905019
University of OxfordPhase 1 / Phase 2
CompletedSeasonal Malaria Chemoprevention With or Without Lipid-based Nutrient Supplement in Children Aged 6-59 Months
NCT03035305
Alliance for International Medical ActionN/A
CompletedSafety, Tolerability and Efficacy of PfSPZ Vaccine in Healthy Children and Infants 5 Months - 9 Years Living i
NCT02687373
Sanaria Inc.Phase 1 / Phase 2
CompletedPhase 2 Efficacy Study of Primaquine and Methylene Blue
NCT02831023
University of California, San FranciscoPhase 2
CompletedInsecticide Resistance Management in Burkina Faso and Côte D'Ivoire
NCT03074435
Institut de Recherche pour le DeveloppementPhase 3
UnknownAzithromycin to Prevent Post-discharge Morbidity and Mortality in Kenyan Children
NCT02414399
University of WashingtonPhase 4
CompletedMalaria Genetic Surveillance in Cambodia
NCT03384472
University of Oxford
CompletedControlled Human Malaria Infection Model for Evaluation of Transmission-Blocking Interventions - Study 1
NCT02836002
Radboud University Medical CenterPhase 1 / Phase 2
WithdrawnSpatial Repellent Products for the Control of Vector Borne Diseases - Malaria - Kenya
NCT02294201
University of Notre DameN/A
WithdrawnLeiden University Medical Center Mini Donor Bank
NCT02810613
Leiden University Medical Center
CompletedPost-discharge Malaria Chemoprevention(PMC) Study
NCT02671175
Liverpool School of Tropical MedicinePhase 3
CompletedPrevention of Malaria With Dihydroartemisinine + Piperaquine for Forest Rangers
NCT02788864
Oxford University Clinical Research Unit, VietnamPhase 4
CompletedMMV390048 and Its Antimalarial Activity Against Plasmodium Falciparum in Healthy Adult Subjects, Part B
NCT02783833
Medicines for Malaria VenturePhase 1 / Phase 2
CompletedSafety, Tolerability and Pharmacokinetic Profile of Ascending Oral Doses of MMV390048, Part A
NCT02783820
Medicines for Malaria VenturePhase 1
CompletedChild Follow-up Until 2 Years
NCT02800109
University of Oxford
CompletedEmpirical ANtibiotic THErapy in Adults Hospitalised With Malaria
NCT03224052
Menzies School of Health Research
UnknownControlled Human Malaria Infection in Semi-Immune Kenyan Adults. (CHMI-SIKA)
NCT02739763
University of OxfordPhase 1
CompletedLumefantrine in Venous Plasma Versus Dried Capillary Blood Spot
NCT02742285
Thierry BuclinPhase 4
CompletedCohort Event Monitoring in Sub Saharan Africa
NCT02817919
African Collaborating Centre for Pharmacovigilance

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