| Not Yet Recruiting | Field Trial of PfSPZ-LARC2 Vaccine in Burkinabe Adults Malaria (Plasmodium Falciparum) | Phase 2 | 2026-04-04 |
| Recruiting | Safety, Tolerability and Efficacy Against Controlled Human Malaria Infection of PfSPZ-LARC2 Vaccine in Malaria Malaria Falciparum | Phase 1 | 2026-04-01 |
| Completed | Age De-escalation Safety Trial of PfSPZ-LARC2 Vaccine in Burkina Faso Malaria Falciparum, Malaria Infection | Phase 1 | 2025-03-04 |
| Terminated | A Phase 1 Trial of PfSPZ Vaccine in Healthy Adults to Determine Safety, Tolerability and Efficacy Against Hete Malaria, Malaria,Falciparum | Phase 1 | 2022-12-06 |
| Completed | Safety, Tolerability, Immunogenicity and Protective Efficacy of PfSPZ Vaccine and PfSPZ-CVac in Indonesian Adu Malaria | Phase 2 | 2022-05-07 |
| Completed | PfSPZ Vaccine Trial in Malian Children Malaria, Malaria,Falciparum | Phase 2 | 2022-04-01 |
| Completed | Safety, Tolerability and Efficacy of PfSPZ Vaccine Against Heterologous CHMI in US Malaria naïve Adults Malaria | Phase 1 | 2021-09-27 |
| Completed | Regimen Optimization Trial of PfSPZ Vaccine in Equatorial Guinea Malaria | Phase 1 | 2018-07-30 |
| Completed | Safety, Tolerability and Protective Efficacy of PfSPZ Vaccine in Gabonese Children Malaria | Phase 2 | 2018-06-14 |
| Completed | Study to Evaluate Safety, Immunogenicity and Efficacy of PfSPZ Vaccine in HIV Negative and HIV Positive Tanzan Malaria, Malaria,Falciparum | Phase 1 | 2018-02-07 |
| Completed | Safety and Protective Efficacy of Genetically Attenuated PfSPZ-GA1 Vaccine in Healthy Dutch Volunteers Malaria | Phase 1 | 2017-05-12 |
| Completed | Safety, Tolerability and Immunogenicity of PfSPZ Vaccine in an Age De-escalation Trial in Equatorial Guinea. Malaria | Phase 1 | 2016-11-01 |
| Completed | Sequential Optimization of Dose and Schedule of PfSPZ Vaccine Malaria | Phase 1 | 2016-08-29 |
| Completed | Safety, Tolerability and Efficacy of PfSPZ Vaccine in Healthy Children and Infants 5 Months - 9 Years Living i Malaria | Phase 1 / Phase 2 | 2016-07-21 |
| Completed | PfSPZ Vaccine: Dose Optimization With Heterologous Challenge in Healthy Malaria-Naïve Adults Malaria | Phase 2 | 2016-01-01 |
| Completed | Safety and Immunogenicity in Age De-Escalation of PfSPZ Vaccine in Tanzanian Adults, Children, and Infants Malaria | Phase 1 | 2015-12-01 |
| Completed | Safety and Immunogenicity of Direct Venous Inoculation of a Radiation-attenuated PfSPZ Vaccine in Equatoguinea Malaria, Plasmodium Falciparum | Phase 1 | 2015-03-01 |
| Completed | Effect of Plasmodium Falciparum Exposure and Sickle Cell Trait on Infection Rates and Kinetics After IV Admini Plasmodium Falciparum Malaria, Malaria | Phase 1 | 2014-07-01 |
| Completed | A Clinical Trial of the PfSPZ Vaccine Administered by Direct Venous Inoculation in Healthy Malaria-Naïve Adult Malaria | Phase 1 | 2014-06-01 |
| Completed | Safety and Protective Efficacy of Intravenous Immunization With Cryopreserved Plasmodium Falciparum Sporozoite Malaria, Plasmodium Falciparum Malaria | Phase 1 | 2014-04-01 |
| Completed | Dose Escalation, Randomized Controlled Trial to Evaluate the Safety, Immunogenicity and Efficacy of Intravenou Malaria, Plasmodium Falciparum Malaria | Phase 1 | 2014-04-01 |
| Completed | Optimization of Controlled Human Malarial Infection by Injection of P. Falciparum Sporozoites in Non-Immune Ad Malaria | Phase 1 | 2012-12-01 |
| Completed | Controlled Human Malaria Infection (CHMI) After Immunization With Cryopreserved Plasmodium Falciparum Sporozoi Malaria, Plasmodium Falciparum | Phase 1 | 2012-09-01 |
| Completed | Controlled Human Malarial Infection by Intravenous Injection of Plasmodium Falciparum Sporozoites in Non-Immun Malaria | Phase 1 | 2012-06-01 |
| Completed | Controlled Human Malaria Infection by Intradermal Injection of Plasmodium Falciparum Sporozoites in Tanzanian Malaria | Phase 1 | 2012-02-01 |
| Completed | Experimental Human Malaria Infection by PfSPZ Malaria | Phase 1 | 2010-08-01 |
| Completed | Clinical Trial of the PfSPZ Vaccine Plasmodium Falciparum | Phase 1 | 2009-04-01 |