NCT05050825

Validation of a CDSA Strategy to Reduce Antibiotic Prescription in Senegal

Validation of an Assisted Medical Care Strategy Composed of a Clinical Decision Support System and RDTs to Reduce Antibiotic Prescription in Non-severe Acute Disease in Children 15 Years Old and Younger in Senegal

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 470 (estimated)
• Sponsor: Foundation for Innovative New Diagnostics, Switzerland · Academic / Other
• Sex: All
• Age: 6 Months – 15 Years
• Healthy volunteers: Not accepted

Summary

This trial aims to validate a novel clinical care strategy based on a electronic clinical decision support algorithm (CDSA) combined with point of care rapid diagnostic tests by evaluating its impact on antibiotic prescription and clinical outcome of children and adolescent presenting at primary healthcare facilities with non-severe acute illness compared to routine practice. The trial also aims to assess the usability of the CDSA strategy. The study will be conducted in primary healthcare facilities across different epidemiological regions of Senegal.

Conditions

• Malaria
• Dengue
• Influenza -Like Illness
• Diarrhea
• Pneumonia
• Acute Febrile Illness

Interventions

Type	Name	Description
OTHER	Patient clinical management based on the CDSA strategy	The CDSA strategy is a combination of point of care tests (rapid diagnostic tests targeting malaria, dengue fever and streptococcus group a sore through) and a mHealth tool that provides patient management recommendations, including treatment, based on an algorithm integrating patient clinical signs and symptoms, history and diagnostic test results.

Timeline

• Start date: 2021-05-03
• Primary completion: 2021-11-30
• Completion: 2021-12-15
• First posted: 2021-09-21
• Last updated: 2021-10-27

Locations

4 sites across 1 country: Senegal