| Not Yet Recruiting | A Post-marketing Observational Study of Oral Cholera Vaccine NCT07300462 | Shanghai United Cell Biotechnology Co., Ltd | Phase 4 |
| Not Yet Recruiting | The Auxiliary Effect of Artificial Intelligence in the Detection of Precancerous Lesions in Proximal Colon Can NCT07338643 | Limian Er | — |
| Recruiting | Rifaximin 200 mg Plus Oral Rehydration vs Oral Rehydration Alone in Children With Acute Diarrhea NCT07285785 | Bausch Health Americas, Inc. | Phase 4 |
| Recruiting | Defining Ileorectal Syndrome: a Prospective Observational Study NCT07385196 | Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital | — |
| Not Yet Recruiting | Radicle GI Health RDH™: A Study Assessing the Impact of Health and Wellness Products on Gastrointestinal (GI) NCT07230821 | Radicle Science | N/A |
| Not Yet Recruiting | Gut Microbiota and Diarrhea in Breast Cancer Patients Receiving Pyrotinib NCT07264985 | Hubei Cancer Hospital | — |
| Not Yet Recruiting | Use of A Complex Gut Bacterial Consortium (MITI 001) for the Treatment of Irritable Bowel Syndrome With Diarrh NCT07238790 | Stanford University | EARLY_Phase 1 |
| Recruiting | First in Human Dose Escalation Study Evaluating the Safety and Immunogenicity of IVT's Shigella-04 Vaccine in NCT07205926 | Inventprise Inc. | Phase 1 |
| Active Not Recruiting | Efficacy and Safety of Encapsulated Bifidobacterium Longum BBH016 in Subjects With Lower Gastrointestinal Symp NCT07484412 | Seoul National University Bundang Hospital | N/A |
| Not Yet Recruiting | Impact of Probiotics on Antibiotic-associated Diarrhea in Community-acquired Pneumonia NCT06990568 | National Health Insurance Service Ilsan Hospital | Phase 4 |
| Not Yet Recruiting | Clinical Study on Fecal Microbiota Transplantation for Diarrhea After Total Pancreatectomy NCT06960122 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Enrolling By Invitation | Effect of Use of Probiotics on Systemic Infection in Critically Ill Patients: a Double Blind, Randomized, Plac NCT07164781 | Benha University | N/A |
| Enrolling By Invitation | Enabling Microbiomics- Driven Personalized Nutrition NCT06657001 | Mayo Clinic | — |
| Not Yet Recruiting | CMTS4520-Assisted Washed Microbiota Transplantation for Chronic Diarrhoea in Adults NCT06839599 | The Second Hospital of Nanjing Medical University | Phase 1 / Phase 2 |
| Recruiting | A Study of SER-155 to Treat Diarrhea in People on Immunotherapy NCT06801067 | Memorial Sloan Kettering Cancer Center | Phase 1 |
| Recruiting | Novel Pilot Study to Treat Symptoms of IBS With Diarrhea Using Combination Therapy of a Low-FODMAP Diet and a NCT06684470 | Mayo Clinic | EARLY_Phase 1 |
| Active Not Recruiting | Microbiota Transplant Therapy for Children With Both Autism Spectrum Disorder and Gastrointestinal Disorders NCT06503978 | Gut-Brain-Axis Therapeutics Inc. | Phase 2 |
| Recruiting | Prophylactic Mesalamine to Prevent Colitis Following Treatment With Ipilimumab/Nivolumab (Ipi/Nivo) NCT05663775 | AHS Cancer Control Alberta | Phase 2 |
| Completed | Meatsafe Food Storage and Diarrhea Prevention Trial in Urban Bangladesh NCT07332078 | University of California, Berkeley | N/A |
| Recruiting | Fecal Microbiota Transplantation for IBS NCT05776914 | Madhusudan (Madhu) Grover, MBBS | Phase 2 |
| Active Not Recruiting | Faecal Microbiota Transplantation Against Chronic Diarrhea in Patients With Systemic Sclerosis NCT06333795 | University of Aarhus | N/A |
| Active Not Recruiting | Evaluation of a Comprehensive School Health Programme in Zambia NCT06560853 | London School of Economics and Political Science | N/A |
| Recruiting | FMT in Checkpoint Inhibitor-mediated Diarrhea and Colitis NCT06206707 | University of Aarhus | N/A |
| Completed | Water Filter Study in Ciudad Victoria NCT06149715 | Aquora Research & Consulting, LLC | N/A |
| Unknown | Buikwe Electronic Community Health Information System Impact Study NCT06318078 | Malaria Consortium | N/A |
| Completed | A Novel Iron Supplement for Athletes: Phase I NCT06285851 | University of Calgary | N/A |
| Unknown | Phase II Clinical Trial of the Inactivated Rotavirus Vaccine NCT06080906 | Institute of Medical Biology, Chinese Academy of Medical Sciences | Phase 2 |
| Recruiting | Cholera-Hospital-Based-Intervention-for-7-Days (CHoBI7) Water, Sanitation, and Hygiene (WASH) Case Area Target NCT06003816 | Johns Hopkins Bloomberg School of Public Health | N/A |
| Recruiting | GI Alpha-Gal Study NCT06268717 | University of North Carolina, Chapel Hill | N/A |
| Active Not Recruiting | Cement flooRs AnD chiLd hEalth (CRADLE) NCT05372068 | Stanford University | N/A |
| Completed | Next Generation ORS: Comparing ORS With Calcium vs Standard ORS in Reducing Severity of Acute Watery Diarrhea NCT05814042 | University of Florida | Phase 2 / Phase 3 |
| Unknown | L. Plantarum 299v and Gut Microbiome, Diarrhoea, and Clostridioides Difficile Infection in Colorectal Cancer P NCT06019312 | Medical University of Gdansk | N/A |
| Completed | Prevention of Traveler's Diarrhea NCT06125626 | University of Palermo | Phase 2 |
| Completed | A Multi-Strain Probiotic Reduces the Frequency of Diarrhea in IBS-D Patients NCT05900752 | Shenzhen Precision Health Food Technology Co. Ltd., | N/A |
| Unknown | Effect of Salovum™ and SPC-Flakes™ on Abemaciclib-induced Gastrointestinal Toxicity in Early Breast Cancer NCT06152471 | Henrik Lindman | Phase 3 |
| Completed | Clinical Study to Assess the Efficacy of IMM-124E (Travelan®) in a Controlled Human Infection Model NCT05933525 | Immuron Ltd. | Phase 2 |
| Completed | The Effectiveness of Local Dry Cold, Hot and Vibration Applications in Peripheral Intravenous Catheterization NCT06378424 | Uludag University | N/A |
| Enrolling By Invitation | Evaluating a Water Safety Plan Intervention in Ghana NCT07317167 | The Aquaya Institute | N/A |
| Recruiting | Lactoferrin and Lysozyme Supplementation for Long-term Diarrhea Sequelae NCT05519254 | University of Washington | Phase 3 |
| Recruiting | Coupons for Safe Water Project NCT05766826 | University of Chicago | N/A |
| Completed | Study for Evaluation of Probiotics in the Re-equilibration of the Intestinal Microbiota, in Paediatric Age NCT06403358 | Labomar SPA | — |
| Unknown | Effect of Aerosol Filtering on Infectious Diseases in Day Care NCT05569330 | Helsinki University Central Hospital | N/A |
| Unknown | The Effect of Abdominal Massage Applied After Surgery NCT05750186 | Istanbul University | N/A |
| Active Not Recruiting | Enterics for Global Health (EFGH) NCT06047821 | University of Washington | — |
| Completed | Assessment of Elemental Impurities Level After Multiple Administration of DWJ1230 or DWB2001 in Subjects With NCT05816681 | Daewoong Pharmaceutical Co. LTD. | Phase 1 |
| Withdrawn | Investigation of Eluxadoline for Diabetic Diarrhea NCT04313088 | Temple University | Phase 2 / Phase 3 |
| Completed | Effects of Probiotic in Treatment of Persistent Diarrhea in Children NCT05812820 | National Children's Hospital, Vietnam | N/A |
| Completed | Trial to Evaluate Dietary Supplements to Maintain Gut Health During Travel NCT04605783 | Henry M. Jackson Foundation for the Advancement of Military Medicine | N/A |
| Recruiting | Prevalence and Natural History of Functional Gastrointestinal Disorders Among At-risk Infants. NCT06031025 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Completed | Study on the Association Between Vitamin C Deficiency and Diarrhea in Children NCT05328037 | Institut Pasteur | — |
| Completed | The Impact of a School-based WASH Intervention on Child Health and School Attendance in Addis Ababa, Ethiopia NCT05024890 | London School of Hygiene and Tropical Medicine | N/A |
| Completed | Utility of the Administration of Chesnut and Quebracho Extract for Irritable Bowel Syndrome Diarrhea Predomina NCT05207618 | Hospital de Clinicas José de San Martín | N/A |
| Completed | Study To Evaluate The Efficacy of a Proprietary Mix of Live Probiotics In The Prophylaxis Of Diarrhea In Adult NCT06283784 | Biofarma | N/A |
| Unknown | Registry and Clinical Observation of Children With Diarrhoeal Disease NCT05052489 | Zhejiang University | — |
| Unknown | Comparing the Efficacy of Anti-secretory Versus Oral Immunoglobulins for Reducing the Episodes of Diarrhea in NCT04885049 | Shaheed Zulfiqar Ali Bhutto Medical University | N/A |
| Completed | Effectiveness and Safety of Lactobacillus Acidophilus LA85 in Preventing Antibiotic-Associated Diarrhea NCT05974657 | Wecare Probiotics Co., Ltd. | N/A |
| Completed | XCHT for Irinotecan-Induced Gut Toxicities (Run-in Study) NCT04926545 | Guangzhou University of Traditional Chinese Medicine | N/A |
| Active Not Recruiting | Wells and Enteric Disease Transmission NCT04826991 | Temple University | N/A |
| Unknown | Validation of a CDSA Strategy to Reduce Antibiotic Prescription in Senegal NCT05050825 | Foundation for Innovative New Diagnostics, Switzerland | N/A |
| Completed | Human Challenge With Live-attenuated Rotavirus to Assess Next-generation Rotavirus Vaccines in Africa NCT04658914 | Centre for Infectious Disease Research in Zambia | Phase 2 |
| Withdrawn | Prospective Assessment of Patients With Neuroendocrine Tumors and Current or Prior History of Carcinoid Syndro NCT04713202 | Chandrikha Chandrasekhara | Phase 2 |
| Recruiting | Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genito NCT04038619 | M.D. Anderson Cancer Center | Phase 1 |
| Unknown | Infection Tracking in Travellers. The Project Aims to Identify Profiles of Travel-associated Illness and to Fo NCT04672577 | Patricia Schlagenhauf | — |
| Completed | Examining the Effect of Ondansetron on Bowel Prep Success NCT05439772 | State University of New York - Downstate Medical Center | Phase 4 |
| Completed | Studies of COVID-19 Patients Treated With Oral Bismuth Subsalicylate (Pepto-Bismol) NCT04811339 | University of Cincinnati | Phase 4 |
| Completed | Implementation of a Minor Ailment Service in Community Pharmacy Practice NCT05247333 | Universidad de Granada | N/A |
| Completed | A Baseline Study in Support of Clinical Evaluation of an Oral Shigella Vaccine Development in Africa NCT04312906 | Centre for Infectious Disease Research in Zambia | — |
| Completed | Remote Guided Caffeine Reduction NCT04560595 | Johns Hopkins University | N/A |
| Unknown | Assessment and Validation of Electronic Gas and Bloating Diary NCT04684849 | Augusta University | — |
| Completed | The Impact of Zinc and Probiotics in Preventing Pediatric Antibiotic-Associated Diarrhea in Southern Iran NCT06665503 | Hormozgan University of Medical Sciences | N/A |
| Terminated | Crofelemer for Functional Diarrhea NCT04486326 | Beth Israel Deaconess Medical Center | Phase 4 |
| Completed | COVID-19 Disease Duration and GIT Manifestations. A New Disease Severity Classification. An Egyptian Experienc NCT04554979 | Cairo University | — |
| Completed | The Efficacy of Asacol (Mesalazine) Suppository on the Treatment of Diarrhea-Induced Acute Fissure NCT05091775 | Shiraz University of Medical Sciences | Phase 1 / Phase 2 |
| Unknown | Bacteriotherapy in the Treatment of COVID-19 NCT04368351 | University of Roma La Sapienza | — |
| Completed | Ciprofloxacin Versus Azithromycin for Children Hospitalised With Dysentery NCT03854929 | Oxford University Clinical Research Unit, Vietnam | Phase 4 |
| Completed | To Assess the Safety and Tolerance of Infant Formula With Locust Bean Gum in Infants With Regurgitation NCT04042454 | Nutricia Research | N/A |
| Unknown | Effect of the Use of Symbiotics in Patients With Colon Cancer NCT04874883 | Federal University of Minas Gerais | Phase 4 |
| Active Not Recruiting | MTT for Children With ASD Who Have Gastrointestinal Disorders NCT04182633 | Arizona State University | Phase 2 |
| Completed | Diarrhea and Stipsis in Critically Ill Patients (NUTRITI) NCT05473546 | Azienda Sanitaria-Universitaria Integrata di Udine | — |
| Unknown | Safety, Tolerability and Preliminary Efficacy of Lenodiar Pediatric in Diarrhea NCT03598010 | Aboca Spa Societa' Agricola | N/A |
| Completed | Effect of L. Rhamnosus Yoba on RTI and Other Health Outcomes Among Children (3-6 Years) in Uganda NCT04144491 | VU University of Amsterdam | N/A |
| Completed | Multi-DOSE Oral Ondansetron for Pediatric Acute GastroEnteritis NCT03851835 | University of Calgary | Phase 3 |
| Completed | Clinical Trial in Children Between 3 Months and 14 Years Old to Evaluate the Efficacy and Safety of Gelatin Ta NCT04065529 | Ferrer Internacional S.A. | Phase 3 |
| Completed | Poultry Management and Child Diarrhea in Uganda NCT04580212 | North Carolina State University | N/A |
| Completed | Drinking Water Chlorination and Child Survival in Rural Kenya NCT04020965 | Tufts University | N/A |
| Unknown | A Nutritional Trial on Effect of L. Rhamnosus Yoba on RTI and Other Health Outcomes Among Children (3-6 Years) NCT03990220 | VU University of Amsterdam | — |
| Completed | Improving Safety of Diagnosis and Therapy in the Inpatient Setting NCT04393909 | Brigham and Women's Hospital | N/A |
| Unknown | Prevention of Radiotherapy Induced Enteropathy by Probiotics (PREP) NCT03978949 | Asan Medical Center | Phase 3 |
| Withdrawn | Effects of Eluxadoline (Viberzi®) 100 mg Twice Daily on Diarrhea-Associated Fecal Incontinence NCT03489265 | University of North Carolina, Chapel Hill | Phase 2 |
| Completed | Response to Rotavirus Vaccine in Infants in Ho Chi Minh City in Vietnam NCT03587389 | Oxford University Clinical Research Unit, Vietnam | Phase 4 |
| Completed | Dose Escalating Study of Intramuscular Invaplex[AR-DETOX] NCT03869333 | PATH | Phase 1 |
| Completed | Phase III Study of Liquid Formulation of ROTAVIN NCT03703336 | Center for Research and Production of Vaccines and Biologicals, Vietnam | Phase 3 |
| Terminated | Point-of-Use Pathogen Identification Tool for Diarrhea NCT03394040 | National Institute of Nursing Research (NINR) | — |
| Completed | Fecal Calprotectin Level in Patients With Nosocomial Diarrhea NCT04491799 | Mahidol University | — |
| Completed | Study of BBIL's ROTAVAC® and ROTAVAC 5CM Vaccines in Zambia NCT03602053 | Centre for Infectious Disease Research in Zambia | Phase 2 / Phase 3 |
| Unknown | Multidrug Resistant Shigella Infection in Bangladesh NCT03778125 | University of Virginia | — |
| Completed | Evaluating an Amino Acid Based Medical Food w/ Diarrhea in Carcinoid Syndrome & Other NETs NCT03722511 | Lowell Anthony, MD | Phase 2 |
| Completed | A Study of Colesevelam for Lenalidomide-Associated Diarrhea NCT03767257 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Completed | The Protective Immune Response to Attenuated Enterotoxigenic Escherichia Coli Infection NCT03596827 | NIZO Food Research | N/A |
| Completed | Evaluation of the Efficacy of Sawyer Point One Filters in Schools and Homes in the Dominican Republic NCT03972618 | Dordt University | N/A |
| Completed | Non-specific Effects of Rabies Vaccine NCT03656198 | Ross University School of Veterinary Medicine | Phase 4 |
| Completed | S1702 Isatuximab in Treating Patients With Relapsed or Refractory Primary Amyloidosis NCT03499808 | SWOG Cancer Research Network | Phase 2 |
| Completed | Study Confirming A Human Challenge Model and Investigating The Safety Of VLA1701 NCT03576183 | Valneva Austria GmbH | Phase 2 |
| Unknown | Liberia National Community Health Assistant (NCHA) Program and Under-five Mortality NCT05123378 | Last Mile Health | N/A |
| Completed | Software Interventions for Improving Hand Washing and Sanitation in Rural Tanzania: an Impact Evaluation NCT03709368 | Centre for Evidence-Based Practice, Belgium | N/A |
| Terminated | A Study Evaluating Bacillus Cereus in the Prevention of Afatinib-associated Diarrhea NCT03486587 | Sun Yat-sen University | Phase 2 |
| Completed | Controlled Study to Evaluate the Efficacy and Safety of Racecadotril in Infants, Children and Adolescents With NCT03463512 | Abbott | Phase 3 |
| Completed | The Safe Start Trial - Kisumu, Kenya NCT03468114 | London School of Hygiene and Tropical Medicine | N/A |
| Completed | Tolerability and Acceptability of Fibersol-2 in Children NCT03565393 | International Centre for Diarrhoeal Disease Research, Bangladesh | Phase 1 / Phase 2 |
| Completed | Evaluation of a mHealth Platform for Diarrheal Disease Decision-support NCT03154229 | University of Florida | N/A |
| Completed | Zinc-MNP Trial for Prevention of Diarrhea and Promotion of Linear Growth NCT03406793 | UCSF Benioff Children's Hospital Oakland | N/A |
| Completed | Dose Escalating Study of a Prototype CS6 Subunit Vaccine With a Modified Heat-labile Enterotoxin From Enteroto NCT03404674 | PATH | Phase 1 |
| Completed | TOX NEG Trial: Clostridium Difficile Diagnosis and Treatment NCT03388268 | Washington University School of Medicine | Phase 4 |
| Unknown | EFFICACY AND SAFETY OF XILOGLUCAN IN ACUTE GASTROENTERITIS IN CHILDREN NCT03357237 | Enriqueta Roamn | N/A |
| Completed | Evidence-based Laboratory Test Order Sets in Primary Care NCT02950142 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Completed | The Pathogenesis of Chronic Diarrhoea After Treatment for Cancer in Cecum and the Ascending Colon NCT04003181 | University of Aarhus | N/A |
| Completed | Sanitation Demand Creation in Peri-Urban Slums of Lusaka, Zambia NCT03174015 | London School of Hygiene and Tropical Medicine | N/A |
| Completed | Dose-finding Study of Colchicine in Type 2 Diabetic Patients With Coronary Artery Disease NCT03376698 | University of the Ryukyus | Phase 2 |
| Completed | Prevention of Diarrheal Disease Due to Infection With Enterotoxigenic E. Coli (ETEC) NCT03729219 | Scandinavian Biopharma AB | Phase 2 |
| Completed | Antibiotics for Children With Severe Diarrhoea NCT03130114 | World Health Organization | Phase 3 |
| Completed | Evaluating the Impact of Automated Evaluation of Gastrointestinal Symptoms (AEGIS) on Clinical Outcomes NCT02530216 | Cedars-Sinai Medical Center | N/A |
| Unknown | Improving Bowel Habits of Elderly With Probiotics and Non-probiotics NCT02949882 | Athena Institute, Netherlands | Phase 4 |
| Completed | C. Difficile and Ursodiol NCT02748616 | NYU Langone Health | Phase 4 |
| Completed | Shigella WRSS1 Vaccine Trial in Bangladesh NCT02934178 | PATH | Phase 1 |
| Terminated | Budesonide for Mycophenolic Acid-induced Diarrhea in Renal Transplant Recipients NCT02991768 | University of Kansas Medical Center | Phase 2 |
| Completed | Zinc Dosing Trial - Does Dose Reduction Reduce Side Effects But Retain Efficacy in Diarrhoea Management NCT03078842 | Ayesha De Costa | N/A |
| Completed | Testing the Effectiveness of a Modified Community Model in Improving Child Health Outcomes in Mashonaland East NCT03176914 | University of Zimbabwe | N/A |
| Unknown | Fecal Calprotectin Levels in Mycophenolate Mofetil Induced Diarrhea and Treatment With Octreotide NCT02977897 | University Health Network, Toronto | — |
| Completed | Trial of Low-cost Microbiological Water Test Kits NCT03021434 | London School of Hygiene and Tropical Medicine | N/A |
| Completed | Chinese Pediatric Massage on Children With Acute Diarrhea: a Randomized Sham Massage Controlled Trial NCT03005821 | Guangzhou University of Traditional Chinese Medicine | N/A |
| Completed | Cholera-Hospital-Based-Intervention-for-7-days NCT04008134 | Johns Hopkins Bloomberg School of Public Health | N/A |
| Completed | Lactobacillus Reuteri DSM 17938 in the Prevention of Antibiotic-associated Diarrhea in Children: Protocol of a NCT02871908 | Medical University of Warsaw | Phase 4 |
| Unknown | Childhood Acute Illness and Nutrition Network NCT03208725 | University of Oxford | — |
| Completed | Probiotic Yogurt Supplement in Reducing Diarrhea in Patients With Metastatic Kidney Cancer Being Treated With NCT02944617 | City of Hope Medical Center | N/A |
| Completed | Impact Evaluation of Urban Water Supply Improvements on Cholera and Other Diarrhoeal Diseases in Uvira, Democr NCT02928341 | London School of Hygiene and Tropical Medicine | N/A |
| Completed | Asili Evaluation in the Democratic Republic of Congo NCT03536286 | Stanford University | N/A |
| Completed | Working With Community Health Workers to Increase ORS Use in Uganda NCT02870491 | University of California, Berkeley | N/A |
| Unknown | Pediatric Antibiotic Associated Diarrhea NCT03265730 | Hacettepe University | — |
| Unknown | Azithromycin to Prevent Post-discharge Morbidity and Mortality in Kenyan Children NCT02414399 | University of Washington | Phase 4 |
| Completed | Evaluation of the Beneficial Effects of a Probiotic Product in Healthy Adult Subjects. NCT03234452 | Montefarmaco OTC SpA | N/A |
| Unknown | Integrated Community Case Management Study in Eastern Province, Zambia NCT02866097 | Zambia Center for Applied Health Research and Development | N/A |
| Completed | Clinical Evaluation of the Use of an mHealth Intervention on Quality of Care NCT03874143 | World Vision Canada | N/A |
| Completed | Prevention of Irinotecan Induced Diarrhea by Probiotics NCT02819960 | S&D Pharma SK s.r.o. | Phase 3 |
| Terminated | Study of the Interactions Between Dientamoba Fragilis and the Gut Microbiota NCT02534272 | University Hospital, Strasbourg, France | — |
| Completed | Evaluation Of The Unilever Lifebuoy School-Based Handwashing Campaign (School Of 5) In Rural Bihar, India NCT02424812 | London School of Hygiene and Tropical Medicine | N/A |
| Withdrawn | The Impact of Anthelmintic Treatment on the Incidence of Diarrheal Disease in Vietnamese School Children NCT02597556 | Oxford University Clinical Research Unit, Vietnam | Phase 4 |
| Completed | Study Comparing Rifaximin With Xifaxan 200 mg in Traveler's Diarrhea NCT02498418 | Actavis Inc. | Phase 3 |
| Completed | Hospital Onset Diarrhoea Investigation NCT03321578 | The Leeds Teaching Hospitals NHS Trust | — |
| Unknown | Safety and Immunogenicity of a Killed Oral Cholera Vaccine in Infants NCT00548054 | International Vaccine Institute | Phase 2 |
| Completed | Epidemiology of Diarrheal Diseases in Pediatric Oncology Patients NCT02464098 | St. Jude Children's Research Hospital | — |
| Terminated | Prevention of Clostridium Difficile-associated Diarrhea by Daily Intake of Kefir NCT02707198 | St. Luke's Hospital of Duluth | Phase 2 |
| Terminated | Probiotics for Prevention of Antibiotic Associated Diarrhea and Clostridium Difficile Associated Disease NCT02076438 | Rutgers, The State University of New Jersey | N/A |
| Unknown | Effectiveness of Oral Rehydration Therapy Supplemented With Zinc in the Management of Diarrhea Acute NCT02601742 | Hospital General Naval de Alta Especialidad - Escuela Medico Naval | Phase 3 |
| Completed | Detection of Exocrine Pancreatic Insufficiency in Patients With Diarrhea and Bloating NCT03407534 | Baylor College of Medicine | — |
| Completed | Heweizhixie capsuleTherapy on Patients With Diarrhea NCT02607176 | Shanghai University of Traditional Chinese Medicine | Phase 4 |
| Completed | Lao Zinc Study: Effects of Two Forms of Daily Preventive Zinc Versus Therapeutic Zinc Supplementation NCT02428647 | University of California, Davis | N/A |
| Completed | Characterization of Resistance Against Live-attenuated Diarrhoeagenic E. Coli NCT02541695 | NIZO Food Research | N/A |
| Unknown | The Clinical Application of MCCES in Examination of Human Colon NCT02536144 | Nanfang Hospital, Southern Medical University | N/A |
| Completed | Automatic Chlorination and Child Health in Urban Bangladesh NCT02606981 | Stanford University | N/A |
| Completed | Probiotics to Prevent Severe Pneumonia and Endotracheal Colonization Trial NCT02462590 | McMaster University | Phase 4 |
| Completed | Randomized Controlled Trial of Social Network Targeting in Honduras NCT02694679 | Yale University | N/A |
| Unknown | Assessing the Health Impact of a Combined Water and Sanitation Intervention in Rural Odisha, India NCT02441699 | London School of Hygiene and Tropical Medicine | — |
| Completed | Impact of the Nutritional Product PTM202 on Acute and Long-Term Recovery From Childhood Diarrheal Disease NCT02385773 | University of Colorado, Denver | N/A |
| Completed | The Effect of an Urban Sanitation Intervention on Child Health NCT02362932 | London School of Hygiene and Tropical Medicine | N/A |
| Terminated | A Study Evaluating a Proprietary Amino Acid Mixture (Enterade®)- for Maintaining Bowel Regularity in Patients NCT02381405 | GenesisCare USA | N/A |
| Completed | Impact of Hand Washing and WASH Educational Intervention on Under-five Diarrheal Diseases NCT02779010 | Ethiopian Institute of Water Resources | N/A |
| Completed | Partnership and Dignity: a Mixed-methods Survey on Supporting and Retaining Uganda's Village Health Teams NCT02374580 | George Washington University | — |
| Completed | Gastrointestinal Dysfunction During Enteral Nutrition in Critically Ill Patients NCT04014816 | Ayancık State Hospital | — |
| Unknown | 64N Nutraceutical for the Prevention of Childhood Diarrhea and Pneumonia in Low Resource Settings NCT02231047 | H2O Health and Agriculture LLC | N/A |
| Completed | Text Message Reminders to Health Workers on Malaria, Pneumonia, and Diarrhea Case Management in Malawi NCT02645513 | Centers for Disease Control and Prevention | N/A |
| Completed | Spillover Effects of Water, Sanitation, and Hygiene Interventions on Child Health NCT02396407 | University of California, Berkeley | N/A |
| Completed | Using Behaviour Change Messaging to Improve Communal Toilets in Dhaka, Bangladesh NCT02324075 | Stanford University | N/A |
| Completed | Efficacy of Rifaximin in Preventing Campylobacteriosis NCT02280044 | Johns Hopkins Bloomberg School of Public Health | Phase 2 / Phase 3 |
| Completed | Head-to-head Comparison of Two Fecal Biomarkers to Screen Children for IBD NCT02197780 | University Medical Center Groningen | — |
| Completed | The Hope Soap Study: a Hand-washing Intervention Among Children in South Africa NCT03280771 | University of Cape Town | N/A |
| Completed | Surveillance Study of Acute Gastroenteritis in Hospitalized Children NCT02245139 | Shaikh Ragheb Harb Hospital | — |
| Unknown | Surveillance Study of Acute Gastroenteritis in Hospitalized Children in Rural Area in Lebanon NCT02177799 | Shaikh Ragheb Harb Hospital | — |
| Completed | Development and Validation of the Automated Evaluation of Gastrointestinal Symptoms (AEGIS) Platform NCT02436057 | Cedars-Sinai Medical Center | N/A |
| Completed | Iron and Prebiotics Fortification in Kenyan Infants NCT02118402 | Swiss Federal Institute of Technology | N/A |
| Completed | Impact of Oral Antibiotic Treatment on C. Difficile NCT02057198 | Duke University | Phase 4 |
| Terminated | German Colon Capsule Registry NCT02182466 | Johann Wolfgang Goethe University Hospital | — |
| Completed | Ondansetron Administration to WELL Children With Gastroenteritis Associated Vomiting in EDs in Pakistan NCT01870635 | Dr. Stephen Freedman | Phase 4 |
| Completed | Impact of Bismuth Subsalicylate on Antimicrobial Use Among Adult Diarrhea Outpatients--Pakistan NCT02047162 | Centers for Disease Control and Prevention | N/A |
| Completed | Ondansetron Administration to Children With Gastroenteritis, Vomiting and SOME Dehydration in EDs in Pakistan NCT01870648 | Dr. Stephen Freedman | Phase 4 |
| Unknown | The Effectiveness of Co-packaging With Zinc to Improve Treatment of Diarrhea and Pneumonia in Guatemala NCT02044107 | Center for Studies of Sensory Impairment, Aging and Metabolism | N/A |
| Completed | An Alternate Dosing Schedule for Pentavalent Rotavirus Vaccine (RotaTeq) NCT01960725 | Dennis Clements | Phase 4 |
| Terminated | CASAD for Severe Diarrhea in the Emergency Department NCT02018653 | M.D. Anderson Cancer Center | N/A |
| Completed | Cesarean Section Study NCT01992497 | Société des Produits Nestlé (SPN) | N/A |
| Completed | Intervention and Mechanisms of Alanyl-Glutamine for Inflammation, Nutrition, and Enteropathy NCT01832636 | Children's Hospital Medical Center, Cincinnati | Phase 3 |
| Completed | Safety Study of Live Attenuated Oral Shigella (WRSS1) Vaccine in Bangladeshi Adults and Children NCT01813071 | PATH | N/A |
| Completed | PK Study of iOWH032 in Adult Male/Female Healthy Volunteers & Adult Males With Cholera NCT01823939 | PATH | Phase 1 |
| Completed | Plasma Citrulline: A Marker for Monitoring & Quantifying Radiation-Induced Small Bowel Toxicity NCT01849107 | Asan Medical Center | N/A |
| Completed | Impact Evaluation of Community-Based Health Programs in Rwanda NCT01836731 | Georgetown University | N/A |
| Completed | Efficacy of a Dietary Supplementation With Lactobacillus Reuteri for Digestive Health in an Elderly Population NCT01837940 | Örebro University, Sweden | Phase 3 |
| Terminated | High Amylose Maize Starch for Treatment of Cholera NCT01823952 | PATH | — |
| Completed | Two Period / Two Treatment Cross-over to Assess the Effect of Florastor® on Gastrointestinal Tolerability, Saf NCT01822028 | Actelion | Phase 1 |
| Completed | Milk Ingredients and Resistance Against E-coli-induced GastroEnteritis (MIRAGE) NCT01800396 | NIZO Food Research | N/A |
| Completed | ACH04 to Assess the Safety and Tolerability in Healthy Adults Subjects NCT02949089 | Ache Laboratorios Farmaceuticos S.A. | Phase 1 |
| Unknown | ZeroTolerance Mucositis: Managing Oral and Alimentary Mucositis With High Potency Sucralfate - ProThelial NCT02016807 | Ashley Downs Bioscience | — |
| Completed | Evaluation of the Dubai Cares WASH in School Initiative NCT01787058 | Emory University | — |
| Completed | Children Immune Functions(2) NCT01731392 | Société des Produits Nestlé (SPN) | N/A |
| Unknown | The Efficacy of CASAD in Patients With Diarrhea Related to Medullary Thyroid Cancer NCT01739634 | Salient Pharmaceuticals Incorporated | Phase 1 / Phase 2 |
| Completed | WASH Benefits Kenya NCT01704105 | Innovations for Poverty Action | N/A |
| Withdrawn | Probiotic Supplementation in Preventing Treatment-Related Diarrhea in Patients With Cancer Undergoing Chemothe NCT01644097 | Stanford University | Phase 2 |
| Completed | Children Immune Functions NCT01717534 | Société des Produits Nestlé (SPN) | N/A |
| Completed | Evaluation of a Pilot Program to Introduce Cholera Vaccine in Haiti as Part of Global Cholera Control Efforts NCT02864433 | Brigham and Women's Hospital | — |
| Completed | Lactobacillus Reuteri DSM 17938 in Preventing Nosocomial Diarrhea in Children NCT01968408 | Medical University of Warsaw | Phase 3 |
| Completed | Live Attenuated ETEC Vaccine ACE527 With and Without dmLT Adjuvant in Adults NCT01739231 | PATH | Phase 1 / Phase 2 |
| Completed | The Effect of Probiotics on E. Coli-induced Gastroenteritis NCT01709266 | NIZO Food Research | N/A |
| Completed | Diarrhea and Bivalent Oral Polio Vaccine Immunity NCT01559636 | Centers for Disease Control and Prevention | N/A |
| Terminated | Cabazitaxel Plus Prednisone With Octreotide For Castration-Resistant Prostate Cancer (CRPC) Previously Treated NCT01469338 | University of Southern California | Phase 2 |
| Unknown | Epidemiological Study of Colorectal Cancer in WuHan NCT01863303 | Wuhan Pu-Ai Hospital | — |
| Unknown | WASH Benefits Bangladesh NCT01590095 | International Centre for Diarrhoeal Disease Research, Bangladesh | N/A |
| Completed | Trial Of Azithromycin In Campylobacter Concisus Patients With Diarrhea NCT01531218 | University of Aarhus | Phase 3 |
| Completed | Zinc Sulphate vs. Zinc Amino Acid Chelate NCT01791608 | CES University | Phase 4 |
| Completed | Vaccine Effectiveness of RV1 in a Naïve Population NCT01467037 | McGill University Health Centre/Research Institute of the McGill University Health Centre | — |
| Completed | Discontinuation of Trimethoprim-sulfamethoxazole Prophylaxis in Adults on Antiretroviral Therapy in Kenya NCT01425073 | University of Washington | N/A |
| Completed | Proof-of-Concept Study in Cancer Patients to Assess Efficacy of Elsiglutide in Preventing Chemotherapy-Induced NCT01543451 | Helsinn Healthcare SA | Phase 2 |
| Completed | Lay Fieldworker Led School Health Program for Rural Primary Schools NCT03423615 | University of Colorado, Denver | N/A |
| Unknown | Influence of Carob and Probiotics on Acute Diarrhea in Children NCT01501305 | Hillel Yaffe Medical Center | Phase 1 / Phase 2 |
| Completed | Study to Compare the Pharmacokinetics Profiles of Four Racecadotril Products NCT01476683 | McNeil AB | Phase 1 |
| Completed | Clinical Evaluation of Ultrasonic Hydration Monitor for Infants NCT01482208 | Artann Laboratories | — |
| Completed | Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoin NCT01371656 | Children's Oncology Group | Phase 3 |
| Terminated | Efficacy and Safety of Lactobacillus Acidophilus/Rhamnosus Combination for the Prevention of Antibiotic-associ NCT01048567 | Vancouver Island Health Authority | Phase 2 |
| Completed | ScopeGuide-assisted Colonoscopy Versus Conventional Colonoscopy NCT01438645 | Christopher Teshima | N/A |
| Terminated | Water-based Zinc Intervention Trial in Zinc Deficient Children NCT01472211 | Swiss Federal Institute of Technology | EARLY_Phase 1 |
| Unknown | Recombinant Human Lactoferrin Administered Orally for the Prevention of Antibiotic Associated Diarrhea in Adul NCT01382199 | Ventria Bioscience | Phase 3 |
| Unknown | Trial of Safe Water Storage Among People Living With HIV NCT01376336 | London School of Hygiene and Tropical Medicine | N/A |
| Completed | Pharmacokinetics and Safety of Tigecycline in the Treatment of Clostridium Difficile Associated Diarrhea (CDAD NCT01401023 | Gary E. Stein, Pharm.D. | N/A |
| Completed | Slow Versus Rapid Rehydration of Severely Malnourished Children NCT02216708 | International Centre for Diarrhoeal Disease Research, Bangladesh | Phase 2 |
| Completed | Sulfasalazine in Preventing Acute Diarrhea in Patients With Cancer Who Are Undergoing Pelvic Radiation Therapy NCT01198145 | Alliance for Clinical Trials in Oncology | Phase 3 |
| Completed | Evaluating the Impact of Community Led Total Sanitation Programs in Mali NCT01900912 | Universidad Nacional de La Plata | N/A |
| Completed | Impact of Preventive and Therapeutic Zinc Supplementation Programs Among Young Children NCT00944359 | University of California, Davis | N/A |
| Completed | Oral Zinc for the Treatment of Acute Diarrhea in US Children NCT01198587 | Boston Children's Hospital | N/A |
| Unknown | Lactobacillus Preparation on the Incidence of Diarrhea NCT01792739 | Seoul National University Hospital | Phase 4 |
| Completed | Intestinal Microbiome and Chemotherapy NCT02875249 | Nantes University Hospital | — |
| Completed | Etiology of Diarrhea in Guinea-Bissau and in Finland NCT01269554 | Bandim Health Project | — |
| Completed | The Effect of Probiotics on E. Coli Gastroenteritis NCT01225042 | NIZO Food Research | N/A |
| Completed | Study of Different Formulations of a Clostridium Difficile Toxoid Vaccine Given at Three Different Schedules i NCT01230957 | Sanofi Pasteur, a Sanofi Company | Phase 2 |
| Completed | Efficacy of Lactobacillus GG With Diosmectite in Treatment Children With Acute Gastroenteritis NCT01657032 | Medical University of Warsaw | Phase 4 |
| Unknown | The Role of Short-course Ceftriaxone Therapy in the Treatment of Severe Nontyphoidal Salmonella Enterocolitis NCT01278017 | Chang Gung Memorial Hospital | Phase 4 |
| Completed | Safety and Immunogenicity of Single Dose Choleragarde® in HIV-Seropositive Adults NCT00741637 | International Vaccine Institute | Phase 2 |
| Terminated | Probiotic Saccharomyces Boulardii for the Prevention of Antibiotic-associated Diarrhoea NCT01143272 | Bernhard Nocht Institute for Tropical Medicine | Phase 3 |
| Completed | Safety and Efficacy Study of WRSS1, a Shigella Sonnei Vaccine Candidate NCT01080716 | U.S. Army Medical Research and Development Command | Phase 1 / Phase 2 |
| Completed | Safety and Immunogenicity Assessment of Rotavin-M1 in Vietnamese Children NCT01502969 | National Institute of Hygiene and Epidemiology, Vietnam | Phase 2 / Phase 3 |
| Completed | Safe Drinking Water For Households With Infants Born to HIV-Positive Mothers Pilot Study NCT01116908 | London School of Hygiene and Tropical Medicine | N/A |
| Completed | Video Capsule Endoscopy (VCE) Comparison Study NCT01090843 | Medical University of Vienna | N/A |
| Completed | Study of CB-183,315 in Participants With Clostridium Difficile Infection NCT01085591 | Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | Phase 2 |
| Withdrawn | Assessment of Gastric Emptying Speed in Patients Who Experience Diarrhea Following a Trigger Meal NCT01114113 | Money, Mary E., M.D. | N/A |
| Completed | Oral Supplement for Pregnant and Lactating Mothers NCT01073033 | Société des Produits Nestlé (SPN) | N/A |
| Completed | Safety and Efficacy Study of a Vaccine Against Enterotoxigenic Escherichia Coli (ETEC) to Prevent Moderate to NCT01060748 | TD Vaccines A/S | Phase 2 |
| Completed | Biomarker-Guided Fluorouracil in Treating Patients With Colorectal Cancer Receiving Combination Chemotherapy NCT01164215 | UNC Lineberger Comprehensive Cancer Center | Phase 1 |
| Completed | Confocal Laser Endomicroscopy (CLE) in Patients With Diarrhea NCT01072110 | University of Erlangen-Nürnberg Medical School | — |
| Completed | Safety and Immunogenicity Study of Traveler's Diarrhea Vaccine Patch NCT01067781 | Intercell USA, Inc. | Phase 2 |
| Completed | Gluten Intolerance in Patients With Diarrhea Predominant Irritable Bowel Syndrome NCT01094041 | Mayo Clinic | N/A |
| Completed | Effectiveness of Rotavirus Immunization in Nicaragua NCT01133808 | Sylvia Becker-Dreps | — |
| Completed | Folic Acid and Vitamin B12 in Young Indian Children NCT00717730 | Tor A. Strand | Phase 2 |
| Unknown | A Study to Investigate the Efficacy of LT-02 in Patients With Mesalazine Refractory Ulcerative Colitis NCT01011322 | Lipid Therapeutics GmbH | Phase 2 |
| Completed | L Reuteri for the Prevention of Nosocomial Diarrhea NCT01046656 | Medical University of Warsaw | Phase 3 |
| Completed | A Dose-escalating Study to Evaluate the Immunogenicity and Safety of Rotavin-M1 Vaccine in Healthy Infants NCT01377571 | National Institute of Hygiene and Epidemiology, Vietnam | Phase 2 |
| Completed | Effect of Bednets and a Water Purification Device on HIV Disease Progression Among ART naïve Patients in Kenya NCT00914225 | University of Washington | — |
| Completed | Safety Study of a Rotavirus Vaccine (Rotavin-M1) Among Healthy Adults NCT01375907 | National Institute of Hygiene and Epidemiology, Vietnam | Phase 1 |
| Terminated | Antibacterial Treatment Against Diarrhea in Oral Rehydration Solution NCT00937274 | Société des Produits Nestlé (SPN) | N/A |
| Completed | Evaluation of Safe-Water Programs in Baja California Sur, Mexico NCT01637389 | University of California, Berkeley | N/A |
| Completed | Community Based Intervention and Evaluation of the Impact of Social Marketing of a Diarrhea Management Pack NCT00942812 | Aga Khan University | Phase 4 |
| Completed | Micronutrient Sprinkles in a Daycare Center NCT00967551 | Emory University | Phase 3 |
| Completed | Lanreotide Autogel in the Symptomatic Treatment of Refractory Diarrhea NCT00891371 | Ipsen | Phase 2 / Phase 3 |
| Completed | Efficacy and Safety of a New Oral Rehydration Solution (Hipp ORS 200 Apple) in Children With Acute Gastroenter NCT01467570 | Medical University of Warsaw | Phase 4 |
| Completed | MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use NCT01050465 | University of Missouri-Columbia | N/A |
| Completed | Calcium Aluminosilicate Anti-Diarrheal in Treating and Preventing Diarrhea in Patients With Metastatic Colorec NCT00748215 | M.D. Anderson Cancer Center | Phase 2 |
| Completed | Study of a Clostridium Difficile Toxoid Vaccine (ACAM-CDIFF™) in Subjects With Clostridium Difficile Infection NCT00772343 | Sanofi Pasteur, a Sanofi Company | Phase 2 |
| Completed | Low-dose Challenge Model With Enterotoxigenic E Coli NCT00844493 | Johns Hopkins Bloomberg School of Public Health | Phase 1 |
| Completed | AcuGraph and Digestive Symptoms NCT00846794 | Logan College of Chiropractic | — |
| Completed | The Treatment Effect of Bio-Three on Children With Enteritis NCT01480947 | Kaohsiung Veterans General Hospital. | Phase 4 |
| Completed | Does Welchol (Colesevelam Hydrochloride) Improve Colonic Transit in Diarrhea-predominant Irritable Bowel Syndr NCT00911612 | Mayo Clinic | Phase 2 |
| Completed | Mass Oral Cholera Vaccination in Zanzibar NCT00709410 | International Vaccine Institute | N/A |
| Completed | Zinc Supplementation and Severe and Recurrent Diarrhea NCT01306097 | Hormozgan University of Medical Sciences | N/A |
| Completed | A Comparison of Three Medications to Treat Diarrhea in Adults. NCT00807326 | McNeil AB | Phase 4 |
| Completed | Evaluation of Zinc and / or Micronutrient Supplementation on Intestinal Flora, Diarrheal Disease Burden, Intes NCT00705445 | Aga Khan University | Phase 2 / Phase 3 |
| Terminated | Safety and Immunogenicity of Peru-15 Vaccine When Given With Measles Vaccine in Healthy Indian and Bangladeshi NCT00624975 | International Vaccine Institute | Phase 2 |
| Unknown | Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development NCT02441426 | Foundation for the National Institutes of Health | — |
| Completed | Study to Determine the Best Way to Measure How Quickly the Drug Can Give Relief From Sudden Diarrhea NCT00685607 | Johnson & Johnson Consumer and Personal Products Worldwide | Phase 4 |
| Completed | Effect of Probiotics on Intestinal Bacterial Population and Immune Modulation NCT00763399 | Chang Gung Memorial Hospital | Phase 4 |
| Completed | Yogurt Study in Children 2-4 Years Old Attending Daycare NCT00760851 | Georgetown University | Phase 3 |
| Completed | Use of Drugs and Constipation in Nursing Homes NCT00849628 | Norwegian University of Science and Technology | — |
| Completed | Evaluation of a Diagnostic Enteric Card for Management of Diarrhea NCT00736567 | PATH | — |
| Completed | Efficacy of BIO-K+ CL1285® Prophylaxis in the Prevention of Traveler's Diarrhea in Adults NCT00737412 | Bio-K Plus International Inc. | Phase 3 |
| Completed | Randomized, Controlled Trial - Lactoferrin Prevention of Diarrhea in Children NCT00560222 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Phase 3 |
| Completed | Surgical and Medical Emergencies on Board of European Aircraft Carriers NCT00713102 | Ruhr University of Bochum | — |
| Completed | Oral Rehydration Solution With Zinc and Prebiotics in Acute Diarrhea NCT01025583 | Federico II University | Phase 2 / Phase 3 |
| Unknown | The Effect of Probiotics on the Immune Status, Diarrhea and Bacterial Vaginosis Cure Rate Among HIV Patients NCT00536848 | National Institute for Medical Research, Tanzania | Phase 2 / Phase 3 |
| Completed | Impact of Home Zinc Treatment for Acute Diarrhea in Children NCT00530829 | Centers for Disease Control and Prevention | Phase 3 |
| Completed | Use of Nitazoxanide and Probiotics in Acute Diarrhea Secondary to Rotavirus NCT00683982 | Centro Pediatrico Albina de Patino | N/A |
| Completed | Calcium, Probiotics and Acute Diarrheal Disease Among Indonesian Children NCT00512824 | Wageningen University | N/A |
| Unknown | Probiotics: is it Really That Good? Cost-Effectiveness of Treating the in-Patient NCT00506181 | Hadassah Medical Organization | Phase 3 |
| Completed | Probiotics in the Management of Acute Rotavirus Diarrhea in Bolivian Children NCT00981877 | Centro Pediatrico Albina de Patino | N/A |
| Completed | Zinc Supplementation to Reduce Diarrhea Rates in Adults in Western Kenya. NCT01166815 | United States Army Research Institute of Environmental Medicine | Phase 2 / Phase 3 |
| Unknown | Randomized Controlled Field Trial of a Probiotics to Assess Its Role in Preventig Diarrhoea NCT00534170 | Indian Council of Medical Research | Phase 3 |
| Completed | Immunogenicity of One Versus Two Doses of Killed Oral Cholera Vaccine NCT00419133 | International Vaccine Institute | Phase 2 |
| Completed | Delivery of Iron and Zinc Supplements: Evaluation of Interaction Effect on Biochemical and Clinical Outcomes NCT00470158 | Johns Hopkins Bloomberg School of Public Health | Phase 4 |