NCT01792739

Lactobacillus Preparation on the Incidence of Diarrhea

The Impact of Lactobacillus Preparation on the Incidence of Diarrhea in Intensive Care Unit-admitted Patients : Randomized Controlled Trial

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 124 (estimated)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this trial is to clarify the impact of lactobacillus preparation on the incidence of diarrhea in ICU-admitted patients. Almost all patients in ICU are treated with antibiotics for the effective control of various infections. However, antibiotics-associated diarrhea is another matter of concern. Many previous studies were proved that the use of probiotic lactobacillus preparation can reduce antibiotics-associated diarrhea in ward-admitted patients. In this study, we are planning to perform a similar study in severely ill patients in ICU.

Conditions

• Diarrhea
• Death
• Pneumonia

Interventions

Type	Name	Description
DRUG	Lactobacillus casei variety rhamnosus granules	Lactobacillus casei variety rhamnosus granules : 3 gram per day (1g-1g-1g, 3 times per day)
DRUG	Placebo	Placebo granules : 3 gram per day (1g-1g-1g, 3 times per day)

Timeline

• Start date: 2010-11-01
• Primary completion: 2013-09-01
• Completion: 2013-10-01
• First posted: 2013-02-15
• Last updated: 2013-02-15

Locations

3 sites across 1 country: South Korea