Clinical Trials Directory

Trials / Sponsors / Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

Industry · 65 registered clinical trials.

StatusTrialPhaseStarted
CompletedStudy of Tedizolid Phosphate in Adolescents With Complicated Skin and Soft Tissue Infection (cSSTI) (MK-1986-0
Skin Diseases, Infectious, Skin Diseases, Bacterial
Phase 32015-03-25
CompletedPlasma Pharmacokinetics (PK) & Lung Penetration of Ceftolozane/Tazobactam in Participants With Pneumonia (MK-7
Critically Ill, Pneumonia
Phase 12015-02-05
CompletedStudy of Pharmacokinetics of a Single IV Dose of CB-238,618 in Subjects With Varying Degrees of Renal Impairme
Healthy Volunteers, Renal Impairment
Phase 12014-12-11
CompletedPharmacokinetic and Safety Study of Ceftolozane/Tazobactam in Pediatric Participants Receiving Antibiotic Ther
Proven or Suspected Gram-negative Bacterial Infection, Peri-operative Prophylaxis
Phase 12014-09-17
CompletedSafety and Efficacy Study of Ceftolozane/Tazobactam to Treat Ventilated Nosocomial Pneumonia (MK-7625A-008)
Healthcare-Associated Pneumonia, Ventilator-Associated Pneumonia, Lung Diseases
Phase 32014-09-02
CompletedTedizolid Phosphate (TR-701 FA, MK-1986) vs Linezolid for the Treatment of Nosocomial Pneumonia (MK-1986-002)
Pneumonia
Phase 32014-01-06
CompletedSafety and Efficacy Study of Daptomycin Compared to Active Comparator in Pediatric Participants With Acute Hem
Acute Hematogenous Osteomyelitis
Phase 32013-09-13
TerminatedSingle Oral Dose of Bevenopran in Patients With Varying Degrees of Renal Impairment
Renal Impairment
Phase 12013-09-01
TerminatedThe Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation
Opioid-Induced Constipation
Phase 32013-07-02
TerminatedStudy of Intravenous Ceftolozane/Tazobactam Compared to Piperacillin/Tazobactam in Ventilator-Associated Pneum
Ventilator-Associated Pneumonia (VAP)
Phase 32013-06-14
TerminatedEfficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation
Opioid-Induced Constipation
Phase 32013-05-20
TerminatedEfficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation
Opioid-Induced Constipation
Phase 32013-04-07
CompletedSafety & Efficacy of Daptomycin Versus Standard of Care (SOC) in 1 - 17 Year Olds With Staphylococcus Aureus B
Bacteremia
Phase 42012-11-29
TerminatedSafety Study of CB-5945 for the Treatment of Opioid-Induced Constipation
Opioid-Induced Constipation
Phase 32012-10-12
CompletedA Study of CB-183,315 in Participants With Clostridium Difficile Associated Diarrhea (MK-4261-006)
Clostridium Difficile Infection
Phase 32012-05-16
CompletedStudy of CB-183,315 in Participants With Clostridium Difficile Associated Diarrhea (MK-4261-005)
Clostridium Difficile Infection
Phase 32012-05-16
CompletedStudy Comparing the Safety and Efficacy of Intravenous CXA-201 and Intravenous Meropenem in Complicated Intraa
Complicated Intra-abdominal Infection
Phase 32011-12-23
CompletedDaptomycin Versus Vancomycin in Participants With Skin Infections Due to MRSA
Staphylococcal Skin Infections
Phase 42011-09-09
CompletedStudy Comparing the Safety and Efficacy of Intravenous CXA-201 and Intravenous Levofloxacin in Complicated Uri
Complicated Urinary Tract Infection, Pyelonephritis
Phase 32011-06-20
CompletedEvaluation of the Efficacy and Safety of ADL5945 Once Daily for the Treatment of Opioid-induced Constipation i
Constipation
Phase 22011-01-19
CompletedEvaluation of the Efficacy and Safety of ADL5945 for the Treatment of Opioid-induced Constipation in Adults Ta
Opioid Induced Constipation
Phase 22010-10-14
TerminatedStudy Comparing Cubicin With Vancomycin in Treatment of Participants With Complicated Skin and Skin Structure
Complicated Skin or Skin Structure Infection
Phase 42010-07-15
CompletedSafety and Efficacy Study to Compare IV CXA 101/Tazobactam and Metronidazole With Meropenem in Complicated Int
Complicated Intra-abdominal Infection
Phase 22010-06-25
CompletedSafety Study Designed to Study the Effects of Two Different Doses of CXA-101/Tazobactam, a Low Dose and a High
Healthy
Phase 12010-06-01
TerminatedStudy of Daptomycin Safety and Efficacy for Complicated Skin and Skin Structure Infections (cSSSI) and Bactere
Complicated Skin and Skin Structure Infections, S. Aureus Bacteremia, Renal Impairment
Phase 42010-04-19
CompletedStudy of CB-183,315 in Participants With Clostridium Difficile Infection
Clostridium Difficile Infection, Diarrhea
Phase 22010-04-01
CompletedClinical Outcomes After Bowel Resection in Patients Receiving Alvimopan Versus Patients Not Receiving Alvimopa
Ileus
2010-04-01
CompletedPharmacokinetics (PK) and Safety Evaluation of Daptomycin in Children Ages 3-24 Months With Proven or Suspecte
Gram Positive Bacterial Infection
Phase 12010-01-05
TerminatedStudy to Assess the Efficacy, Safety, and Tolerability of ADL5747 in Participants With Postherpetic Neuralgia
Postherpetic Neuralgia
Phase 22010-01-01
CompletedEfficacy and Safety Study Evaluating ADL5859 and ADL5747 in Participants With Pain Due to Osteoarthritis of th
Osteoarthritis of the Knee
Phase 22009-10-01
CompletedSafety and Efficacy of IV CXA-101 and IV Ceftazidime in Patients With Complicated Urinary Tract Infections
Complicated Urinary Tract Infection
Phase 22009-06-30
CompletedOutcomes and Safety Trial Investigating Ecallantide's Effect on Reducing Surgical Blood Loss Volume in Subject
Bloodloss, Surgical Procedures, Operative
Phase 22009-06-01
CompletedStudy to Evaluate Daptomycin Given During Dialysis and After Dialysis
End-stage Renal Disease, Renal Failure Chronic Requiring Hemodialysis
Phase 12009-04-29
CompletedA Study of Alvimopan for the Management of Postoperative Ileus in Participants Undergoing Radical Cystectomy
Postoperative Ileus
Phase 42009-03-01
CompletedA Dose-ranging Safety and Efficacy Study of Ecallantide to Reduce Surgical Blood Loss Volume
Bloodloss, Surgical Procedures, Operative
Phase 22009-03-01
TerminatedPhase 4 Efficacy and Safety Study of Cubicin® With and Without Combination Therapy in S. Aureus Infective Endo
Infective Endocarditis
Phase 42009-02-13
TerminatedPhase 2 Study of Safety, Efficacy, and Pharmacokinetics of Higher Doses of Daptomycin and Vancomycin in MRSA B
Endocarditis, Bacterial, Infective Endocarditis
Phase 22008-09-17
CompletedSafety and Efficacy Study of Daptomycin in Pediatric Participants (1 to 17 Years-old) With Skin and Skin Struc
Skin Diseases, Infectious
Phase 42008-07-23
CompletedPK and Safety Evaluation of Daptomycin in Children Ages 2-6 With Proven or Suspected Gram-positive Infections
Gram Positive Infection, Concurrent Antibiotic Treatment
Phase 12008-06-03
CompletedSafety and Efficacy Study of ADL5859 in Participants With Neuropathic Pain Associated With Diabetic Peripheral
Peripheral Neuropathy, Neuropathic Pain
Phase 22007-11-01
CompletedStudy Evaluating the Analgesic Efficacy and Safety of ADL5859 in Participants With Rheumatoid Arthritis
Rheumatoid Arthritis
Phase 22007-10-01
CompletedSafety Study to Evaluate Daptomycin in Non-infected Adults Who Are Either on Hemodialysis or Continuous Ambula
End-Stage Renal Disease
Phase 12007-08-12
CompletedStudy of Daptomycin in Subjects Undergoing Surgery for Osteomyelitis Associated With an Infected Prosthetic Ca
Osteomyelitis
Phase 22007-06-26
CompletedAnalgesic Efficacy and Safety of ADL5859 in Subjects With Acute Dental Pain After Third Molar Extraction
Acute Pain
Phase 22007-06-01
TerminatedEfficacy Study of Recombinant Protein (Ecallantide) to Reduce Blood Loss During Primary Coronary Bypass Grafti
Blood Loss, Surgical
Phase 22007-05-01
CompletedPhase 2 Safety and Efficacy Study of Daptomycin in Complicated Skin and Skin Structure Infections
Soft Tissue Infections
Phase 22007-01-01
TerminatedClinical Evaluation Of Alvimopan (SB767905) On Constipation And Related Symptoms Associated With Opioid
Cancer, Constipation
Phase 22006-04-01
CompletedStudy Comparing CUBICIN® (Daptomycin for Injection) With Vancomycin in Cellulitis or Erysipelas
Cellulitis
Phase 42006-02-20
CompletedStudy of Single Dose Daptomycin in Pediatric Patients With Gram-positive Infection for Which They Are Receivin
Gram-positive Bacterial Infections
Phase 12005-08-24
CompletedLong-Term Safety Evaluation Of Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer
Bowel Dysfunction, Constipation
Phase 32005-08-01
CompletedTreatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain
Bowel Dysfunction, Constipation
Phase 32005-08-01
CompletedAlvimopan For The Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain
Bowel Dysfunction, Constipation
Phase 32005-08-01
TerminatedDaptomycin in the Treatment of Patients With Renal Insufficiency and Complicated Skin and Skin Structure Infec
Soft Tissue Infections
Phase 42005-01-01
CompletedStudy 767905/008 Extension Study: Alvimopan for Treatment of Opioid-Induced Bowel Dysfunction in Cancer Pain S
Cancer, Bowel Dysfunction
Phase 22004-09-01
CompletedStudy of Alvimopan for the Management of Opioid-induced Postoperative Bowel Dysfunction/Postoperative Ileus
Ileus
Phase 32004-06-01
TerminatedCubicin(R) for Complicated Post-surgical Wound Infections
Wound Infections
Phase 42004-06-01
CompletedStudy Of Alvimopan Drug For Treatment Of Constipation Due To Prescription Pain Medication
Constipation, Bowel Dysfunction
Phase 22003-10-01
TerminatedDaptomycin for the Treatment of Infections Due to Gram-Positive Bacteria
Gram-Positive Bacterial Infections
Phase 32002-12-19
CompletedDaptomycin in the Treatment of Subjects With Infective Endocarditis or Bacteremia Due to S. Aureus
Bacterial Endocarditis, Bacteremia
Phase 32002-03-01
CompletedStudy of Alvimopan for the Management of Opioid-induced Postoperative Bowel Dysfunction/Postoperative Ileus
Ileus
Phase 32002-01-01
CompletedStudy of Alvimopan for the Management of Opioid-induced Postoperative Bowel Dysfunction/ Postoperative Ileus
Ileus
Phase 32001-12-01
CompletedStudy of Cidecin™ (Daptomycin) to Rocephin® (Ceftriaxone) in the Treatment of Moderate to Severe Community-Acq
Pneumonia, Bacterial
Phase 32001-07-30
CompletedStudy of Alvimopan for the Management of Opioid-induced Postoperative Bowel Dysfunction/Postoperative Ileus
Ileus
Phase 32001-03-01
CompletedComparative Study of Cidecin™ (Daptomycin) to Rocephin® (Ceftriaxone) in the Treatment of Moderate to Severe C
Pneumonia, Bacterial
Phase 32000-10-31
TerminatedHepeX-B in Post Hepatic Allografts for Treatment of End Stage Liver Disease Due to Hepatitis B Infection
Hepatitis B, Liver Transplantation
Phase 2