Clinical Trials Directory

Trials / Recruiting

RecruitingNCT06801067

A Study of SER-155 to Treat Diarrhea in People on Immunotherapy

A Single-Arm, Open-Label, Phase 1 Study to Assess Safety and Preliminary Efficacy of Cultivated Multi-Strain Live Bacterial Therapeutic SER-155 for First-Line Treatment of Immunotherapy-Related Enterocolitis

Status
Recruiting
Phase
Phase 1
Study type
Interventional
Enrollment
15 (estimated)
Sponsor
Memorial Sloan Kettering Cancer Center · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to find out whether SER-155 may be a safe first treatment that causes few or mild side effects for people due to irEC.

Conditions

Interventions

TypeNameDescription
BIOLOGICALSER-155SER-155 (Cultivated Multi-Strain Live Bacterial Therapeutic, Encapsulated) is an experimental designed ecology of 16 unique, human-commensal bacterial strains encapsulated for oral administration and will be provided by Seres as an investigational drug

Timeline

Start date
2025-01-24
Primary completion
2027-01-24
Completion
2027-01-24
First posted
2025-01-30
Last updated
2025-12-02

Locations

7 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT06801067. Inclusion in this directory is not an endorsement.

A Study of SER-155 to Treat Diarrhea in People on Immunotherapy (NCT06801067) · Clinical Trials Directory