| Not Yet Recruiting | A Study to Evaluate the Efficacy and Safety of E2086 in Adults With Narcolepsy Narcolepsy | Phase 2 | 2026-03-23 |
| Recruiting | A Study to Determine the Metabolism and Excretion of [14C]E2086 in Healthy Male Participants Healthy Volunteers | Phase 1 | 2025-12-31 |
| Recruiting | A Study of Oral E1018 in Healthy Adult Participants Malaria, Healthy Participants | Phase 1 | 2025-02-26 |
| Active Not Recruiting | A Study to Assess the Pregnancy Outcome in Women Exposed to Dayvigo® During Pregnancy Compared to an Unexposed Sleep Initiation and Maintenance Disorders, Pregnancy | — | 2025-01-03 |
| Active Not Recruiting | A Study of E2814 With Concurrent Lecanemab Treatment in Participants With Early Alzheimer's Disease Alzheimer's Disease | Phase 2 | 2024-09-30 |
| Completed | A Study of E2086 in Healthy Adult Participants Healthy Volunteers | Phase 1 | 2024-06-25 |
| Completed | A Study to Evaluate the Efficacy, Safety, and Tolerability of E2086 Compared to Placebo and Active Comparator Narcolepsy Type 1 (NT1) | Phase 1 | 2024-06-20 |
| Active Not Recruiting | A Study of BB-1701 in Previously Treated Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Pos Breast Cancer | Phase 2 | 2024-04-10 |
| Completed | A Study To Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2086 in Healthy Adult a Healthy Volunteers | Phase 1 | 2023-02-20 |
| Completed | A Study to Assess the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamics of E2025 in Healthy Volunteers | Phase 1 | 2023-02-06 |
| Completed | A Study to Demonstrate the Bioequivalence of Lecanemab Supplied in Vials and a Single-Use Auto-Injector (AI) i Healthy Volunteers | Phase 1 | 2022-09-06 |
| Completed | A Study to Assess the Safety and Tolerability of E2511 in Healthy Adult and Elderly Participants Healthy Volunteers | Phase 1 | 2021-12-01 |
| Completed | A Study of E7386 in Combination With Pembrolizumab in Previously Treated Participants With Selected Solid Tumo Melanoma, Carcinoma, Hepatocellular, Colorectal Neoplasms | Phase 1 / Phase 2 | 2021-10-27 |
| Completed | A Study of Subcutaneous Lecanemab in Healthy Participants Healthy Volunteers | Phase 1 | 2021-09-07 |
| Completed | A Study to Assess Safety and Target Engagement of E2814 in Participants With Mild to Moderate Cognitive Impair Alzheimer Disease | Phase 1 / Phase 2 | 2021-06-28 |
| Completed | A Study of Remitoro in Participants With Recurrent or Refractory Peripheral T Cell Lymphoma and Cutaneous T Ce Lymphoma, T-cell, Peripheral, Lymphoma, T-cell, Cutaneous | — | 2021-05-24 |
| Completed | A Study to Evaluate Lemborexant in Milk of Healthy Lactating Women Healthy Volunteers | Phase 1 | 2021-05-17 |
| Completed | A Study to Evaluate the Safety and Tolerability of Lenvatinib in Participants With Advanced or Unresectable He Carcinoma, Hepatocellular | — | 2021-04-09 |
| Completed | A Study of E2027 in Participants With Dementia With Lewy Bodies (DLB) or Parkinson's Disease Dementia (PDD) Wi Lewy Body Disease, Parkinson Disease | Phase 2 | 2021-02-25 |
| Completed | A Study to Evaluate the Respiratory Safety of Lemborexant in Adult and Elderly Participants With Moderate to S Sleep Apnea, Obstructive, Pulmonary Disease, Chronic Obstructive, Respiration Disorders | Phase 1 | 2021-01-06 |
| Completed | A Study to Assess the Safety and Tolerability of E2730 After Multiple Dose and the Food Effect After Single Do Healthy Volunteers | Phase 1 | 2020-12-16 |
| Terminated | A Study of Lorcaserin as Adjunctive Treatment in Participants With Dravet Syndrome Epilepsies, Myoclonic | Phase 3 | 2020-09-23 |
| Completed | A Study to Assess the Safety and Tolerability of E2511 in Healthy Participants Healthy Volunteers | Phase 1 | 2020-09-14 |
| Recruiting | A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ec Solid Tumor | Phase 1 / Phase 2 | 2020-08-06 |
| Active Not Recruiting | AHEAD 3-45 Study: A Study to Evaluate Efficacy and Safety of Treatment With Lecanemab in Participants With Pre Preclinical Alzheimer's Disease, Early Preclinical Alzheimer's Disease | Phase 3 | 2020-07-14 |
| Completed | A Study to Determine the Signs and Symptoms That Impact Daily Life of Participants With Irregular Sleep-Wake R Irregular Sleep Wake Rhythm Disorder | — | 2020-07-09 |
| Active Not Recruiting | A Study of H3B-6545 in Combination With Palbociclib in Women With Advanced or Metastatic Estrogen Receptor-Pos Receptors, Estrogen, Genes, Erbb-2, Breast Neoplasms | Phase 1 | 2020-04-01 |
| Completed | A Study to Compare the Efficacy and Safety of Ifosfamide and Etoposide With or Without Lenvatinib in Children, Osteosarcoma | Phase 2 | 2020-03-23 |
| Terminated | Study of Intratumorally Administered Stimulator of Interferon Genes (STING) Agonist E7766 in Participants With Lymphoma, Advanced Solid Tumors | Phase 1 | 2020-02-24 |
| Withdrawn | A Study of Stimulator of Interferon Genes (STING) Agonist E7766 in Non-muscle Invasive Bladder Cancer (NMIBC) Urinary Bladder Neoplasms | Phase 1 | 2020-02-13 |
| Completed | A Study to Assess Safety, Tolerability, Pharmacokinetics (PK), Immunogenicity, and Pharmacodynamics (PD) of In Healthy Volunteers | Phase 1 | 2019-12-16 |
| Completed | A Study to Determine the Metabolism and Elimination of [14C]E2027 in Healthy Male Participants Dementias With Lewy Bodies | Phase 1 | 2019-07-18 |
| Completed | A Study to Evaluate Next-Dose Transition From Zolpidem to Lemborexant (LEM) for the Treatment of Insomnia Insomnia | Phase 3 | 2019-07-15 |
| Active Not Recruiting | A Study of E7386 in Combination With Other Anticancer Drug(s) in Participants With Solid Tumor Endometrial Neoplasms, Neoplasms, Carcinoma, Hepatocellular | Phase 1 / Phase 2 | 2019-07-11 |
| Completed | A Food-Effect Study of E7386 in Healthy Participants Food Effect in Healthy Participants | Phase 1 | 2019-06-07 |
| Recruiting | A Study to Evaluate Efficacy and Safety of Perampanel Administered as an Adjunctive Therapy in Pediatric Parti Pediatric Epileptic Syndrome, Partial-onset Seizures | Phase 2 | 2019-05-31 |
| Active Not Recruiting | A Study to Confirm Safety and Efficacy of Lecanemab in Participants With Early Alzheimer's Disease Early Alzheimer's Disease | Phase 3 | 2019-03-27 |
| Terminated | A Study to Evaluate the Pharmacodynamic Activity of E2082 in Adult Participants With Photosensitive Epilepsy Photosensitive Epilepsy | Phase 2 | 2018-10-31 |
| Completed | Study to Assess the Long-term Safety of Lenvatinib Monotherapy, a Lenvatinib Combination Regimen, or a Compara Solid Tumors | Phase 2 | 2018-08-16 |
| Completed | A Study to Demonstrate Bioequivalence Between Lorcaserin Extended Release (XR) Tablets Manufactured in Kawashi Healthy Participants | Phase 1 | 2018-08-07 |
| Terminated | A Study to Evaluate the Pharmacodynamic Activity of E2730 in Adult Participants With Photosensitive Epilepsy Photosensitive Epilepsy | Phase 2 | 2018-07-27 |
| Completed | A Post-marketing Observational Study on Risk Factors for Hepatic Encephalopathy in Participants With Unresecta Carcinoma, Hepatocellular | — | 2018-07-02 |
| Completed | Lenvatinib in Combination With Pembrolizumab Versus Treatment of Physician's Choice in Participants With Advan Endometrial Neoplasms | Phase 3 | 2018-06-11 |
| Completed | Study To Evaluate the Efficacy, Safety and Tolerability of E2027 (Hereinafter Referred to as Irsenontrine) in Dementia With Lewy Bodies | Phase 2 | 2018-05-04 |
| Terminated | Trial to Evaluate Safety and Efficacy of Treatment of Physician Choice (TPC) Following First-Line Treatment of Carcinoma, Hepatocellular | Phase 2 | 2018-04-26 |
| Completed | Study to Assess Safety and Preliminary Activity of Eribulin Mesylate in Pediatric Participants With Relapsed/R Relapsed/Refractory Rhabdomyosarcoma, Non-rhabdomyosarcoma Soft Tissue Sarcoma, Ewing Sarcoma | Phase 2 | 2018-04-17 |
| Completed | A Study to Evaluate Safety, Tolerability and Efficacy of Eribulin Mesylate in Treating Adult Females With Loca Breast Neoplasms | Phase 4 | 2018-03-28 |
| Completed | Study of Lemborexant-Alcohol Interaction in Healthy Subjects Healthy Subjects | Phase 1 | 2018-03-12 |
| Completed | Study Evaluating the Safety and Efficacy of Eribulin Mesilate in Combination With Irinotecan Hydrochloride in Refractory or Recurrent Solid Tumors, Rhabdomyosarcoma, Non-Rhabdomyosarcoma Soft Tissue Sarcoma | Phase 1 / Phase 2 | 2018-03-05 |
| Completed | Study to Evaluate the Respiratory Safety of Lemborexant in Adult and Elderly Healthy Subjects and Adult and El Obstructive Sleep Apnea, Healthy Subjects | Phase 1 | 2018-02-21 |
| Completed | A Study to Assess the Safety, Tolerability, and Pharmacokinetics of E2730 in Healthy Participants Healthy Participants | Phase 1 | 2018-02-09 |
| Completed | Study to Evaluate the Pharmacokinetics of Lemborexant (E2006) and Its Metabolites in Subjects With Normal Rena Renal Impairment | Phase 1 | 2018-02-07 |
| Completed | Study to Assess the Pharmacokinetic Drug-Drug Interactions of Lemborexant When Coadministered With an Oral Con Healthy Subjects | Phase 1 | 2018-02-05 |
| Completed | Study to Evaluate the Pharmacokinetics of Lemborexant (E2006) and Its Metabolites in Subjects With Mild and Mo Hepatic Impairment | Phase 1 | 2018-01-26 |
| Completed | A Study to Evaluate the Food-Effect of H3B-6527 Healthy Participants | Phase 1 | 2017-12-27 |
| Completed | A Study of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin) in Participants With Solid Tumors Solid Tumors | Phase 1 | 2017-11-28 |
| Completed | Study of Lenvatinib in Combination With Everolimus in Recurrent and Refractory Pediatric Solid Tumors, Includi Recurrent and Refractory Solid Tumors | Phase 1 / Phase 2 | 2017-11-16 |
| Completed | Study to Evaluate Bioavailability of a Single 12 mg Dose of Perampanel for Three Intravenous Infusion Duration Healthy Participants | Phase 1 | 2017-11-08 |
| Terminated | Study to Evaluate the Efficacy and Safety of Belviq XR® in Conjunction With Lifestyle Modification for Weight Obesity | Phase 4 | 2017-09-28 |
| Completed | Study to Evaluate the Efficacy and Safety of Perampanel as Monotherapy or First Adjunctive Therapy in Subjects Partial Onset Seizures, Secondarily Generalized Seizures, Primary Generalized Tonic-Clonic Seizures | Phase 4 | 2017-08-23 |
| Completed | Trial of H3B-6545, in Women With Locally Advanced or Metastatic Estrogen Receptor-positive, HER2 Negative Brea Breast Neoplasms, Breast Cancer, Estrogen-receptor Positive Breast Cancer | Phase 1 / Phase 2 | 2017-08-23 |
| Completed | Trial to Assess Safety and Efficacy of Lenvatinib (18 mg vs. 14 mg) in Combination With Everolimus in Particip Renal Cell Carcinoma | Phase 2 | 2017-08-17 |
| Active Not Recruiting | Study of E7386 in Participants With Selected Advanced Neoplasms Advanced Neoplasms | Phase 1 | 2017-07-27 |
| Completed | A Trial of Lenvatinib (E7080) in Subjects With Iodine-131 Refractory Differentiated Thyroid Cancer to Evaluate Thyroid Cancer | Phase 2 | 2017-06-08 |
| Completed | A Study to Determine the Abuse Potential of Single Oral Doses of Lemborexant Compared to Zolpidem, Suvorexant Insomnia Disorders | Phase 1 | 2017-04-19 |
| Completed | Study to Investigate Dosage, Efficacy, and Safety of Fycompa in Routine Clinical Care of Patients With Epileps Epilepsy | — | 2017-04-07 |
| Completed | Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E6742 in Healthy Adult Sub Healthy Participants | Phase 1 | 2017-03-03 |
| Completed | Pharmacokinetic Study With an Oral Suspension of Perampanel as Adjunctive Therapy in Pediatric Subjects With E Epilepsy | Phase 2 | 2017-02-20 |
| Completed | A Trial to Evaluate Efficacy and Safety of Lenvatinib in Combination With Everolimus in Subjects With Unresect Non Clear Cell Renal Cell Carcinoma (nccRCC) | Phase 2 | 2017-02-20 |
| Completed | Study to Assess the Safety, Tolerability, and Pharmacokinetics of E2730 Healthy Participants | Phase 1 | 2017-01-31 |
| Completed | Study of Lemborexant for Irregular Sleep-Wake Rhythm Disorder and Mild to Moderate Alzheimer's Disease Dementi Irregular Sleep-Wake Rhythm Disorder | Phase 2 | 2016-12-20 |
| Terminated | Study of Perampanel as Adjunctive Treatment for Inadequately Controlled Seizures Associated With Lennox-Gastau Lennox-Gastaut Syndrome (LGS) | Phase 3 | 2016-12-13 |
| Completed | Phase 0 Study in Healthy, Hepatic and Renal Impaired Subjects to Obtain Plasma for Lenvatinib Protein Binding Hepatic Impairment; Renal Impairment | EARLY_Phase 1 | 2016-12-02 |
| Completed | Crossover Study to Evaluate the Effect of Lemborexant Versus Placebo and Zolpidem on Postural Stability, Audit Healthy Subjects | Phase 1 | 2016-11-21 |
| Completed | Perampanel as Adjunctive Therapy in Pediatrics With Partial Onset Seizures or Primary Generalized Tonic Clonic Partial-Onset or Primary Generalized Tonic-Clonic Seizures | Phase 3 | 2016-11-16 |
| Completed | Long-term Study of Lemborexant in Insomnia Disorder (SUNRISE 2) Insomnia Disorder | Phase 3 | 2016-11-15 |
| Active Not Recruiting | Lenvatinib/Everolimus or Lenvatinib/Pembrolizumab Versus Sunitinib Alone as Treatment of Advanced Renal Cell C Renal Cell Carcinoma | Phase 3 | 2016-10-13 |
| Completed | A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2027 in Healthy Subject Healthy Subjects | Phase 1 | 2016-08-10 |
| Completed | A Study to Evaluate the Pharmacokinetics of E2609 and Its Metabolites in Subjects With Mild and Moderate Hepat Early Alzheimer's Disease | Phase 1 | 2016-08-01 |
| Terminated | Study of Eribulin Mesylate in Combination With PEGylated Recombinant Human Hyaluronidase (PEGPH20) Versus Erib Metastatic Breast Cancer | Phase 1 / Phase 2 | 2016-07-13 |
| Terminated | A Phase 2 Trial of Lenvatinib for the Treatment of Anaplastic Thyroid Cancer (ATC) Thyroid Carcinoma, Anaplastic | Phase 2 | 2016-07-07 |
| Completed | Study of the Efficacy and Safety of Lemborexant in Subjects 55 Years and Older With Insomnia Disorder (SUNRISE Insomnia | Phase 3 | 2016-05-31 |
| Completed | Phase 1 Study to Determine the Effect of Lenvatinib (E7080) on the Pharmacokinetics of Midazolam in Subjects W Tumors | Phase 1 | 2016-04-18 |
| Completed | Study to Investigate Dosage, Efficacy, and Safety of Perampanel Given as Monotherapy in Patients With Epilepsy Epilepsy, Partial-Onset Seizures, Primary Generalized Tonic-Clonic Seizures | — | 2016-04-01 |
| Completed | Study to Assess Pharmacokinetic Drug-Drug Interaction Between Avatrombopag When Co-Administered With Fluconazo Healthy Participants | Phase 1 | 2016-04-01 |
| Completed | Study to Evaluate the Effect of Lemborexant Versus Placebo on Driving Performance in Healthy Adult and Elderly Healthy Participants | Phase 1 | 2015-11-01 |
| Completed | Study to Evaluate the Efficacy and Safety of Eribulin Mesylate in Combination With Pembrolizumab in Participan Breast Neoplasm | Phase 1 / Phase 2 | 2015-08-28 |
| Terminated | Study of E7046 in Subjects With Selected Advanced Malignancies Tumors | Phase 1 | 2015-07-30 |
| Completed | A Trial of Lenvatinib (E7080) Plus Pembrolizumab in Participants With Selected Solid Tumors Tumors | Phase 1 / Phase 2 | 2015-07-22 |
| Completed | Study to Assess the Safety, Tolerability, Pharmacokinetics of E2027 in Healthy Adult and Elderly Subjects, and Healthy Participants | Phase 1 | 2015-07-01 |
| Completed | Study to Evaluate the Efficacy and Safety of Eribulin Mesylate Administered Biweekly (Q2W) for Participants Wi Breast Cancer | Phase 2 | 2015-06-16 |
| Completed | A Study to Assess the Efficacy and Safety of Farletuzumab (MORAb 003) in Combination With Carboplatin Plus Pac Platinum-Sensitive Ovarian Cancer in First Relapse | Phase 2 | 2015-03-19 |
| Completed | A Single Dose Pharmacokinetic Study of Lorcaserin Hydrochloride in Obese Pediatric Subjects 6 to 11 Years of A Obesity | Phase 1 | 2015-03-01 |
| Withdrawn | To Evaluate the Effect of Perampanel on Objective and Subjective Sleep in Subjects With Insomnia and Partial O Epilepsy, Partial | Phase 4 | 2015-03-01 |
| Completed | Study to Evaluate the Effect of 2 Dosage Strengths of Lemborexant (E2006) on a Multiple Sleep Latency Test in Insomnia Disorder | Phase 1 | 2014-12-13 |
| Withdrawn | A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of 3 Subcutaneous and 1 I Crohn's Disease | Phase 1 | 2014-12-01 |
| Terminated | Dose-Finding Study To Evaluate Safety, Tolerability, and Efficacy of E2609 in Participants With Mild Cognitive Alzheimer Disease, Dementia, Alzheimer Type | Phase 2 | 2014-11-26 |
| Completed | A Study to Demonstrate Bioequivalence Between a 12-mg Dose of an Oral Suspension Formulation of Perampanel and Healthy Subjects | Phase 1 | 2014-09-01 |
| Completed | A Study to Evaluate the Effects of E2609 on QTc Interval in Healthy Subjects Healthy Subjects | Phase 1 | 2014-08-01 |
| Completed | Crossover Study to Evaluate the Relative Bioavailability and Palatability of a Lenvatinib Suspension Compared Healthy Volunteers | Phase 1 | 2014-08-01 |
| Completed | This is a Phase 1 Study of Eribulin Mesylate in Pediatric Participants With Recurrent or Refractory Solid Tumo Pediatrics, Solid Tumors | Phase 1 | 2014-07-31 |
| Completed | Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2609 in Healthy Adult M Healthy Subjects | Phase 1 | 2014-07-01 |
| Completed | A Global, Postmarketing Observational Safety Study to Evaluate the Safety and Tolerability of Fycompa (Perampa Epilepsy | — | 2014-06-06 |
| Completed | An Open-Label, Single-Dose Study to Determine the Metabolism and Elimination of 14C-Perampanel in Healthy Male Healthy Subjects | Phase 1 | 2014-05-01 |
| Completed | A 2-Part Study to Assess Potential Metabolism-Based Drug-Drug Interactions of E2006 When Coadministered With I Healthy Subjects | Phase 1 | 2014-02-01 |
| Completed | Treatment of Thrombocytopenia in Patients With Chronic Liver DiseaseUndergoing an Elective Procedure Thrombocytopenia Associated With Liver Disease | Phase 3 | 2014-02-01 |
| Completed | An Open-label, Single-dose Study to Determine the Metabolism and Excretion of [14C]E2006 in Healthy Male Subje Metabolism and Excretion | Phase 1 | 2014-02-01 |
| Completed | A Study to Determine the Effect of a High-Fat Meal on the Rate and Extent of E2006 Absorption in Healthy Subje Healthy Subjects | Phase 1 | 2014-02-01 |
| Completed | A Study to Evaluate the Effect of Long-term Treatment With BELVIQ (Lorcaserin HCl) on the Incidence of Major A Cardiovascular Disease, High Cardiovascular Risk, Obesity | Phase 4 | 2014-01-24 |
| Completed | A Two-Part Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2006 in Heal Healthy Volunteers | Phase 1 | 2014-01-01 |
| Completed | A 3-Part, Open-Label, Drug-Drug Interaction Study of Concomitant Administration of E2609 With Itraconazole, Ri Healthy Subjects | Phase 1 | 2014-01-01 |
| Completed | A Five-Treatment-Period Study to Evaluate the Single-Dose Pharmacokinetics and Pharmacodynamics of Avatrombopa Thrombocytopenia | Phase 1 | 2013-12-01 |
| Completed | Single Dose Study to Determine the Safety, Tolerability, and Pharmacokinetic Properties of Lorcaserin Hydrochl Pharmacokinetics in Obese Adolescents | Phase 1 | 2013-12-01 |
| Completed | A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Bayesian Adaptive Randomization D Chronic Insomnia, Adults, Elderly | Phase 2 | 2013-11-13 |
| Completed | Treatment of Thrombocytopenia in Patients With Chronic Liver Disease Undergoing an Elective Procedure Thrombocytopenia Associated With Liver Disease | Phase 3 | 2013-11-01 |
| Completed | A Multicenter, Double-blind, Randomized, Parallel-group, Pilot Study of 12-week Duration to Assess the Short-t Chronic Weight Management | Phase 4 | 2013-10-30 |
| Completed | Bioequivalence Study to Evaluate the Impact of Varying Crystalline Polymorph Forms for the Commercial Oral Cap Healthy Volunteers | Phase 1 | 2013-07-01 |
| Completed | An Open-label, Single Dose Study to Determine the Metabolism and Elimination of [14C]E2609 in Healthy Male Sub Metabolism and Elimination | Phase 1 | 2013-06-01 |
| Completed | A Trial of E7777 in Persistent and Recurrent Cutaneous T-Cell Lymphoma Persistent or Recurrent Cutaneous T-Cell Lymphoma | Phase 3 | 2013-05-30 |
| Completed | Study of the Safety and Activity of Lenvatinib (E7080) in Subjects With KIF5B-RET-Positive Adenocarcinoma of t KIF5B-RET-Positive Adenocarcinoma of the Lung | Phase 2 | 2013-04-05 |
| Completed | A Study to Evaluate Safety, Tolerability, and Efficacy of Lecanemab in Subjects With Early Alzheimer's Disease Alzheimer's Disease | Phase 2 | 2012-12-20 |
| Completed | An Study to Determine the Bioavailability of E2609 Tablets Compared to Capsules and the Effect of Food on Abso Alzheimer's Disease | Phase 1 | 2012-10-01 |
| Completed | A Open-label, Three-period, Partial-replicate Design Study to Evaluate the Inter- and Intrasubject Variability Healthy Volunteers | Phase 1 | 2012-10-01 |
| Completed | 2-Part Multiple Ascending Dose Study for Safety and Pharmacokinetics in Healthy and Elderly Subjects CNS | Phase 1 | 2012-08-01 |
| Completed | Open-Label Study of Bioavailability of E2006 Tablet Versus Capsule Formulations Insomnia | Phase 1 | 2012-08-01 |
| Completed | Evaluation of E2609 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Alzheimer's Disease (St Alzheimer's Disease | Phase 1 | 2012-07-01 |
| Terminated | Phase 2 Study of the Poly(ADP-Ribose) Polymerase Inhibitor E7016 in Combination With Temozolomide in Subjects Wild Type BRAF Stage IV Melanoma, Unresectable Stage III Melanoma | Phase 2 | 2012-05-01 |
| Completed | A Post-marketing Study Evaluating Eslicarbazepine Acetate (ESL) as Adjunctive Treatment in Partial-Onset Seizu Partial Onset Seizures | — | 2012-04-01 |
| Terminated | A Phase 3, Multicenter, Randomized, Double-blind,Active-controlled, Parallel-group Trial With an Open-labelExt Idiopathic Thrombocytopenic Purpura | Phase 3 | 2012-03-26 |
| Completed | A Post-marketing Observational Study Of The Use Of Zonisamide (ZNS) in the Adjunctive Treatment Of Adult Patie Partial Onset Seizures | — | 2012-03-01 |
| Completed | Efficacy and Safety of Oral E5501 Plus Standard of Care for the Treatment of Thrombocytopenia in Adults With C Chronic Thrombocytopenia, Immune Thrombocytopenia | Phase 3 | 2012-02-16 |
| Completed | A Study in Healthy Subjects to Evaluate Bioavailability of 4 Formulations of E5501 Idiopathic Thrombocytopenic Purpura | Phase 1 | 2012-01-01 |
| Completed | Pharmacokinetics, Efficacy, and Safety of Perampanel Oral Suspension on Seizure Frequency in Pediatric Subject Central Nervous System | Phase 2 | 2012-01-01 |
| Completed | A Randomized, Open-label, Multicenter, Phase 3 Study to Compare the Efficacy and Safety of Eribulin With Treat Non-Small Cell Lung Cancer (NSCLC) | Phase 3 | 2011-12-09 |
| Completed | Evaluation of the Safety, Pharmacokinetics, and Pharmacodynamics of Multiple Doses of E2609 in Healthy Subject Healthy | Phase 1 | 2011-12-01 |
| Completed | Chronic Hepatitis C Virus Related Thrombocytopenia to Evaluate the Effects of E5501 Thrombocytopenia | Phase 2 | 2011-11-01 |
| Terminated | E7050 in Combination With Cisplatin and Capecitabine Versus Cisplatin and Capecitabine Alone in Patients With Advanced or Metastatic Solid Tumors, Previously Untreated Gastric Cancer | Phase 1 / Phase 2 | 2011-11-01 |
| Completed | A Pharmacokinetic Study to Assess the Influence of P-glycoprotein Inhibition and Simultaneous CYP3A4 and P-gly P-glycoprotein, Healthy Volunteers | Phase 1 | 2011-11-01 |
| Completed | A Study Comparing the Combination of the Best Supportive Care Plus E7080 Versus Best Supportive Care Alone, in Non-Small Cell Lung Cancer | Phase 2 | 2011-11-01 |
| Completed | A Phase 1, Open-Label, Single-Dose, Pharmacokinetic and Safety Study of E7080 (24 mg) Administered to Subjects Renal Impairment, Disease Severity | Phase 1 | 2011-11-01 |
| Terminated | A Study of E7050 in Combination With E7080 in Participants With Advanced Solid Tumors (Dose Escalation) and in Advanced Solid Tumors | Phase 1 / Phase 2 | 2011-10-13 |
| Completed | A 2-Part Single Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2006 Insomnia | Phase 1 | 2011-10-05 |
| Completed | An Open-Label Study to Assess the Pharmacokinetics and Safety of HALAVEN in Subjects With Cancer Who Also Have Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | 2011-10-01 |
| Terminated | Irinotecan Plus E7820 Versus FOLFIRI in Second-Line Therapy in Patients With Locally Advanced or Metastatic Co Colon Cancer, Rectal Cancer | Phase 1 / Phase 2 | 2011-09-30 |
| Completed | E7050 in Combination With Cetuximab Versus Cetuximab Alone in the Treatment of Platinum-Resistant Squamous Cel Platinum-Resistant Squamous Cell Carcinoma of the Head and Neck | Phase 1 / Phase 2 | 2011-09-19 |
| Completed | A Efficacy and Safety Study of Adjunctive Perampanel in Primary Generalized Tonic Clonic Seizures Seizure Disorder Generalized Tonic Clonic | Phase 3 | 2011-09-01 |
| Completed | Pharmacokinetic and Pharmacodynamic Study in Healthy Subjects Comparing the Interactions Between E5501 and Ver Idiopathic Thrombocytopenic Purpura (ITP) | Phase 1 | 2011-09-01 |
| Completed | Eribulin in Combination With Capecitabine for Adjuvant Treatment in Estrogen Receptor-Positive Early Stage Bre Estrogen Receptor Positive Tumor, Breast Cancer | Phase 2 | 2011-08-01 |
| Completed | E7050 in Combination With Sorafenib Versus Sorafenib Alone as First Line Therapy in Participants With Hepatoce Hepatocellular Carcinoma | Phase 1 / Phase 2 | 2011-07-19 |
| Completed | An Open-label, Dose Escalation, Pharmacodynamic, Pharmacokinetic, and Effect of Food Phase 1 Study of E7820 to Advanced Solid Tumors | Phase 1 | 2011-06-30 |
| Completed | Study of Rufinamide in Pediatric Subjects 1 to Less Than 4 Years of Age With Lennox-Gastaut Syndrome Inadequat Lennox-Gastaut Syndrome | Phase 3 | 2011-06-16 |
| Completed | A Pharmacokinetic and Safety Study of E7080 in Subjects With Mild (10 mg), Moderate (10 mg), and Severe Hepati Hepatic Impairment, Hepatic Function | Phase 1 | 2011-06-01 |
| Completed | Efficacy Study of Pharmacokinetic(PK)/Pharmacodynamic(PD) Relationship of Monotherapy MORAb-004 in Metastatic Metastatic Melanoma | Phase 2 | 2011-05-16 |
| Completed | A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Trial of Lenvatinib (E7080) in 131I-Refractory Di Thyroid Cancer | Phase 3 | 2011-03-17 |
| Completed | Phase 3 Study to Compare the Efficacy and Safety of Eribulin With Dacarbazine in Subjects With Soft Tissue Sar Soft Tissue Sarcoma | Phase 3 | 2011-03-10 |
| Completed | Dose Dense Doxorubucin and Cyclophosphamide Followed by Eribulin Mesylate for the Adjuvant Treatment of Early HER2-normal | Phase 2 | 2011-03-03 |
| Terminated | Efficacy and Safety of Decitabine as Epigenetic Priming With Induction Chemotherapy in Pediatric Acute Myeloge Pediatric Acute Myelogenous Leukemia (AML) | Phase 2 | 2011-03-03 |
| Approved For Marketing | An Open-Label, Multi-Center, Expanded Access Program With Eribulin for the Treatment of Advanced Breast Cancer Metastatic Breast Cancer | — | 2011-03-01 |
| Withdrawn | A Phase 3 Trial of E7777 in Combination With CHOP Compared With CHOP Alone for the First-Line Treatment of Per Peripheral T-Cell Lymphoma | Phase 3 | 2011-03-01 |
| Completed | Subject Variability in Two Lots of E5501 Administered to Fed and Fasted Healthy Subjects Purpura, Thrombocytopenic, Idiopathic, Acute Idiopathic Thrombocytopenic Purpura, Chronic Thrombocytopenia | Phase 1 | 2011-02-01 |
| Completed | A Study of Single-Agent Eribulin Mesylate as First-Line Therapy for Locally Recurrent or Metastatic Human Epid Locally Recurrent, Metastatic Breast Cancer ( HER2 Negative) | Phase 2 | 2011-02-01 |
| Completed | A Pharmacokinetic Study to Assess the Influence of Simultaneous CYP3A4 and P-glycoprotein Inhibition on E7080 Healthy Volunteers | Phase 1 | 2011-02-01 |
| Completed | A Study to Characterize Pharmacokinetics (PK) and Pharmacodynamics (PD) of LUSEDRA® Administered as Continuous Monitored Anesthesia Care | Phase 1 | 2011-01-01 |
| Completed | A Study Versus E2020 10mg Followed by an Open-label Extension Phase to Explore the Safety of E2020 SR 23 mg in Alzheimer's Type Dementia | Phase 2 | 2011-01-01 |
| Completed | A Study to Evaluate the Safety and Efficacy of Zonisamide an Antiepileptic Drug as Monotherapy or Adjunctive T Partial, Generalized and Combined Seizures | — | 2011-01-01 |
| Completed | Demonstrate Bioequivalence Between 6 ? 2-mg Tablets of Perampanel and a Single 12-mg Tablet of Perampanel in H Healthy | Phase 1 | 2010-12-01 |
| Completed | Evaluation of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2609 in Healthy Subjects an Alzheimer's Disease | Phase 1 | 2010-12-01 |
| Completed | Eribulin With Trastuzumab as First-line Therapy for Locally Recurrent or Metastatic HER2 Positive Breast Cance Breast Cancer | Phase 2 | 2010-12-01 |
| Completed | A Double-Blind Study in Healthy Volunteers to Assess the Effect of E7080 on the QTc Interval Refractory Solid Tumors, Lymphomas | Phase 1 | 2010-12-01 |
| Completed | A Study to Evaluate the Relative Bioavailability and Intra-Subject Variability of Two Lots of E5501 40 mg Tabl Idiopathic Thrombocytopenia Purpura | Phase 1 | 2010-12-01 |
| Completed | Demonstrate Bioequivalence Between 3 x 2-mg Tablets of Perampanel and a Single 6-mg Tablet of Perampanel in He Healthy | Phase 1 | 2010-12-01 |
| Completed | A Study in Subjects With Recurrent Malignant Glioma Glioma | Phase 2 | 2010-11-09 |
| Completed | A PK/PD Study of Fospropofol Disodium Compared With Propofol Injectable Emulsion Anesthesia | Phase 4 | 2010-11-01 |
| Completed | A Study to Assess the Transfer of Fospropofol and Its Active Metabolite, Propofol, to Breast Milk Following Ad Lactating Women | Phase 1 | 2010-11-01 |
| Completed | A Study to Evaluate the Effects of Diltiazem, a Moderate CYP3A4/A5 Inhibitor, on the Pharmacokinetics and Phar Healthy Subjects | Phase 1 | 2010-10-01 |
| Completed | Randomized, Placebo-controlled Study to Evaluate Effects of E5555 on Renal Function Parameters and OCT2 Activi Healthy Subjects | Phase 1 | 2010-10-01 |
| Completed | A Randomized, Double-Blind, Placebo-Controlled, Ascending Single Dose Study of E6007 in Healthy Subjects Inflammatory Bowel Disease | Phase 1 | 2010-09-01 |
| Completed | A Study With an Open-label Extension Phase to Evaluate the Effect of Perampanel (E2007) on Cognition, Growth, Epilepsy | Phase 2 | 2010-09-01 |
| Completed | A Study of E7080 Alone, and in Combination With Everolimus in Subjects With Unresectable Advanced or Metastati Metastatic Renal Cell Carcinoma | Phase 1 / Phase 2 | 2010-08-05 |
| Completed | A Randomized, Double-blind, Placebo-controlled, Combined Single Ascending Dose and Multiple Ascending Dose Stu Alzheimer's Disease | Phase 1 | 2010-08-01 |
| Completed | Compassionate Use of Eribulin for the Treatment of Advanced Breast Cancer Refractory to All Other Marketed The Breast Cancer | N/A | 2010-08-01 |
| Completed | An Open-Label, 2-Cohort, Multicenter, Study of Lenvatinib in Previously Treated Subjects With Unresectable Sta Unresectable Stage III, Stage IV Melanoma | Phase 2 | 2010-08-01 |
| Completed | E7080 Food Effect Study in Healthy Subjects Cancer | Phase 1 | 2010-07-01 |
| Completed | Single and Multiple Dose Asian Bridging Study Healthy Subjects | Phase 1 | 2010-07-01 |
| Completed | A Study to Evaluate the Effect on 24-hour, Intragastric pH of RAB ER 50-mg Capsules Compared With Esomeprazole Healthy | Phase 1 | 2010-07-01 |
| Completed | Study of Denileukin Diftitox in Participants With Stage IIIC and Stage IV Melanoma Stage IIIC Melanoma, Stage IV Melanoma | Phase 2 | 2010-06-22 |
| Completed | Eribulin Mesylate Administered in Combination With Pemetrexed Versus Pemetrexed Alone as Second Line Therapy i Non Small Cell Lung Cancer | Phase 1 / Phase 2 | 2010-06-10 |
| Withdrawn | A Randomized Study of Epigenetic Priming Using Decitabine With Front Line Induction Chemotherapy Compared With Acute Myelogenous Leukemia (AML) | Phase 2 | 2010-06-01 |
| Completed | A Study to Demonstrate Bioequivalence Between 6 x 2 mg Tablets of Perampanel and a Single 12 mg Tablet of Pera Partial Onset Epilepsy | Phase 1 | 2010-06-01 |
| Terminated | Eribulin Mesylate Administered in Combination With Gemcitabine Plus Cisplatin Versus Gemcitabine Plus Cisplati Bladder Cancer | Phase 1 / Phase 2 | 2010-04-16 |
| Completed | E7080 (Lenvatinib) in Combination With Dacarbazine Versus Dacarbazine Alone as First Line Therapy in Patients Stage IV Melanoma | Phase 1 / Phase 2 | 2010-04-01 |
| Completed | A Dose-ranging Study to Evaluate the Safety and Efficacy of LUSEDRA (Fospropofol Disodium) as an Intravenous S Sedation | Phase 4 | 2010-04-01 |
| Terminated | Study of Poly (ADP-Ribose) Polymerase (PARP) Inhibitor E7016 in Combination With Temozolomide in Subjects With Solid Tumors | Phase 1 | 2010-03-29 |
| Terminated | FOLFIRI Alone Versus FOLFIRI Plus Bevacizumab Versus FOLFIRI Plus E7820 as Second-Line Therapy in Patients Wit Colorectal Cancer | Phase 1 / Phase 2 | 2010-03-04 |
| Completed | A Study to Investigate the Potential Pharmacokinetic Interaction of Perampanel With Oral Contraceptives in Hea Partial Onset Epilepsy | Phase 1 | 2010-03-01 |
| Completed | Study of Lenvatinib in Subjects With Advanced Endometrial Cancer and Disease Progression Endometrial Cancer | Phase 2 | 2010-03-01 |
| Terminated | E7080 in Combination With Carboplatin + Gemcitabine Versus Carboplatin + Gemcitabine Alone as Second Line Ther Ovarian Cancer | Phase 1 / Phase 2 | 2010-03-01 |
| Completed | Eribulin Mesylate in Combination With Intermittent Erlotinib in Patients With Previously Treated, Advanced Non Non-small Cell Lung Cancer | Phase 2 | 2010-02-22 |
| Completed | A Single-Center, Open-Label, Randomized, 3-Treatment Crossover Bioavailability Study of Single Oral Doses of E Healthy Subjects | Phase 1 | 2010-01-01 |
| Completed | A Randomized, Double-blind, Placebo-controlled, Sequential Ascending, Single-dose Study to Evaluate the Safety Alzheimer's Disease | Phase 1 | 2010-01-01 |
| Completed | Escalation Study to Determine Bioavailability of a Single Oral Dose of Decitabine in Patients With Myelodyspla Myelodysplastic Syndrome | Phase 1 | 2009-12-01 |
| Terminated | To Demonstrate Superiority of Decitabine Over Azacitidine in Subjects With Intermediate- or High-risk MDS. Myelodysplastic Syndromes | Phase 4 | 2009-11-01 |
| Completed | A Study of Palonosetron for the Prevention of Chemotherapy-Induced Nausea and Vomiting (CINV) in Participants Patients With Confirmed Malignant Disease to Receive Low Emetogenic Chemotherapy (LEC) or Who Experienced at Least Nausea and Vomiting During Last Cycle of LEC | Phase 2 | 2009-10-27 |
| Completed | Evaluation of the Efficacy and Safety of Adjunctive Zonisamide vs Replacement With Zonisamide of the Last Adde Partial Seizures | Phase 4 | 2009-09-01 |
| Completed | Pilot Study to Assess Palonosetron Versus Ondansetron as Rescue Medication in Subjects That Develop Postoperat Postoperative Nausea and Vomiting | Phase 2 | 2009-07-13 |
| Completed | Evaluating the Efficacy and Safety of Oral Ranirestat (40 and 80 mg) in Mild to Moderate Diabetic Sensorimotor Mild to Moderate Diabetic Sensorimotor Polyneuropathy | Phase 2 / Phase 3 | 2009-07-01 |
| Completed | A Study to Determine the Metabolism and Elimination of 14C-E7080 in Patients With Advanced Solid Tumors or Lym Advanced Solid Tumors, Lymphomas | Phase 1 | 2009-06-01 |
| Completed | Once-Daily Oral Avatrombopag Tablets Used in Subjects With Chronic Liver Diseases and Thrombocytopenia Prior t Thrombocytopenia Related to Chronic Liver Disease | Phase 2 | 2009-05-01 |
| Completed | A Study Comparing Eribulin Mesylate and Ixabepilone in Causing or Exacerbating Neuropathy in Participants With Breast Cancer | Phase 2 | 2009-03-31 |
| Completed | A Dose-Finding Study of E7050 Administered Orally to Patients With Advanced Solid Tumors Cancer | Phase 1 | 2009-03-01 |
| Completed | A Study to Determine the Metabolism and Elimination of Carbon-14 Labeled Eribulin Acetate (14C-Eribulin) in Pa Advanced Solid Tumors | Phase 1 | 2009-03-01 |
| Completed | Comparing the Efficacy, Safety, and Tolerability of Rabeprazole ER 50 mg With Placebo in Subjects With Symptom Symptomatic Gastroesophageal Reflux Disease (sGERD) | Phase 3 | 2009-01-01 |
| Completed | Abuse Potential of Single Doses of Lorcaserin in Healthy Recreational Polydrug Users Drug Abuse, Healthy | Phase 1 | 2008-12-01 |
| Completed | Efficacy and Safety of Adjunctive Zonisamide in Paediatric Partial Onset Seizures (CATZ Study) Epilepsy; Paediatric Partial Onset Seizures | Phase 3 | 2008-12-01 |
| Completed | Evaluating the Safety and Efficacy of Oral Lenvatinib in Medullary and Iodine-131 Refractory, Unresectable Dif Thyroid Cancer | Phase 2 | 2008-11-06 |
| Completed | Pharmacokinetic Properties of Lorcaserin in the Fed and Fasted State Obesity | Phase 1 | 2008-11-01 |
| Completed | To Assess the Effect of Lorcaserin Hydrochloride on Energy Metabolism and Food Intake Obesity | Phase 1 | 2008-11-01 |
| Completed | Assessing The Long-Term Safety And To Explore The Long-Term Efficacy Of Zonisamide As Monotherapy In Newly Dia Epilepsy | Phase 3 | 2008-10-01 |
| Completed | Evaluation of the Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refra Epilepsy | Phase 3 | 2008-10-01 |
| Completed | Pharmacokinetic Properties of Lorcaserin in Subjects With Renal Impairment Renal Impairment | Phase 1 | 2008-10-01 |
| Completed | Pharmacokinetic Properties of Lorcaserin in Obese or Overweight Elderly Subjects Obesity | Phase 1 | 2008-10-01 |
| Terminated | A Study of Eritoran (E5564) Administered IV Over 14 Days Prior to and During Bone Marrow Engraftment in BMT Pa Leukemia | Phase 1 | 2008-09-01 |
| Terminated | Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysf Down Syndrome, Cognitive Dysfunction | Phase 3 | 2008-09-01 |
| Terminated | Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysf Down Syndrome, Cognitive Dysfunction | Phase 3 | 2008-09-01 |
| Completed | Rabeprazole Extended-Release 50 mg vs. Ranitidine 150 mg for Maintenance of Healed Erosive Gastroesophageal Re Gastroesophageal Reflux Disease (GERD) | Phase 3 | 2008-08-31 |
| Completed | Pharmacokinetic Properties of Lorcaserin in Subjects With Hepatic Impairment Hepatic Impairment | Phase 1 | 2008-08-01 |
| Completed | Rabeprazole Extended Release 50 mg Versus Ranitidine 150 mg for Maintenance of Healed Erosive Gastroesophageal Gastroesophageal Reflux Disease (GERD) | Phase 3 | 2008-08-01 |
| Completed | Evaluating Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refractory P Refractory Partial Seizures | Phase 3 | 2008-08-01 |
| Completed | Efficacy and Safety of Donepezil Hydrochloride in Preadolescent and Adolescent Children With Attention Impairm Attention Impairment | Phase 3 | 2008-07-02 |
| Completed | A Phase 1, Multicenter, Open-Label, Dose-Escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of E62 Advanced Solid Tumors | Phase 1 | 2008-06-22 |
| Completed | To Evaluate The Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refract Refractory Partial Seizures | Phase 3 | 2008-05-01 |
| Completed | A Study of Decitabine Given Subcutaneously to Adults With Low or Intermediate-1 Risk Myelodysplastic Syndromes Myelodysplastic Syndrome | Phase 2 | 2008-05-01 |
| Completed | Evaluating the Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refracto Refractory Partial Seizures | Phase 3 | 2008-04-30 |
| Terminated | Evaluating The Safety Of Donepezil Hydrochloride (Aricept) For Up To 1 Year In The Treatment Of The Cognitive Down Syndrome | Phase 2 | 2008-04-04 |
| Completed | ZAGAL Study: Evaluating Effectiveness and Tolerability of Zonisamide as Adjunctive Therapy in Patients With Pa Epilepsy | Phase 4 | 2008-04-01 |
| Completed | Rabeprazole Extended-Release 50 mg Versus Esomeprazole 40 mg for Healing and Symptomatic Relief of Mild to Mod Gastroesophageal Reflux Disease (GERD) | Phase 3 | 2008-02-01 |
| Completed | Study Of Eribulin (E7389) In Patients With Advanced Solid Tumors And Normal Or Reduced Hepatic Function As Per Cancer | Phase 1 | 2008-02-01 |
| Completed | Rabeprazole Extended-Release 50 mg Versus Esomeprazole 40 mg for Healing and Symptomatic Relief of Moderate to Gastroesophageal Reflux Disease (GERD) | Phase 3 | 2008-02-01 |
| Completed | Rabeprazole Extended-Release, 50 mg, Versus Esomeprazole, 40 mg, for Healing and Symptomatic Relief of Moderat Gastroesophageal Reflux Disease (GERD) | Phase 3 | 2008-02-01 |
| Withdrawn | Evaluating The Impact Of Donepezil Hydrochloride (Aricept) On Behavioral And Psychological Symptoms In Patient Severe Alzheimer's Disease | Phase 4 | 2008-01-01 |
| Completed | BLOSSOM: Behavioral Modification and Lorcaserin Second Study for Obesity Management Obesity | Phase 3 | 2008-01-01 |
| Completed | Evaluating E2007 (Perampanel) in Patients With Painful Diabetic Neuropathy (PDN) or Post-Herpetic Neuralgia (P Neuralgia | Phase 2 / Phase 3 | 2008-01-01 |
| Completed | The Effectiveness And Safety Of Donepezil Hydrochloride (E2020) In Subjects With Mild To Severe Alzheimer's Di Mild to Severe Alzheimer's Disease | Phase 4 | 2008-01-01 |
| Completed | Dose-Tolerability Titration Study to Evaluate The Efficacy And Safety Of Perampanel (E2007) In Patients With P Neuralgia | Phase 2 | 2008-01-01 |
| Completed | Open-Label Extension Study of 23 mg Donepezil SR in Participants With Moderate to Severe Alzheimer's Disease Alzheimer's Disease | Phase 3 | 2007-12-14 |
| Completed | Exploratory Study, Evaluating the Treatment Effect of Surgery Plus GLIADEL® Wafer in Patients With Metastatic Metastatic Brain Cancer | Phase 2 | 2007-12-12 |
| Completed | BLOOM-DM: Behavioral Modification and Lorcaserin for Overweight and Obesity Management in Diabetes Mellitus Obesity | Phase 3 | 2007-12-01 |
| Completed | Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (HCl) (Aricept) In Treating Cognitive Dysfunctio Down Syndrome | Phase 2 | 2007-11-16 |
| Completed | Safety and Tolerability of E5555 and Its Effects on Markers of Intravascular Inflammation in Subjects With Acu Acute Coronary Syndrome | Phase 2 | 2007-10-01 |
| Terminated | Assessment of Perampanel (E2007) on Synaptic Dopamine in Mild-moderate PD Patients: A Pilot Study With [^123I] Parkinson's Disease | Phase 2 | 2007-10-01 |
| Completed | A Phase II Study of the Safety and Efficacy of E7820 Plus Cetuximab in Colorectal Cancer, Preceded by a Run-in Advanced Colorectal Cancer | Phase 2 | 2007-09-24 |
| Completed | Paired-Comparison Study Evaluating the Efficacy and Safety of E6201 Versus Vehicle for the Treatment of Plaque Chronic Plaque Psoriasis | Phase 2 | 2007-09-01 |
| Completed | Safety and Tolerability of E5555 and Its Effects on Markers of Intravascular Inflammation in Subjects With Cor Coronary Artery Disease | Phase 2 | 2007-09-01 |
| Completed | Neural Correlates In Mild Alzheimer's Disease Alzheimer's Disease | Phase 4 | 2007-07-23 |
| Suspended | A Dose Escalation Study of E7107 Administered Intravenously on Days 1 and 8 Every 21 Days to Patients With Sol Cancer | Phase 1 | 2007-07-01 |
| Completed | An Evaluation of the Efficacy and Safety of E2007 in Patients With Painful Diabetic Neuropathy Diabetic Neuropathy | Phase 2 / Phase 3 | 2007-06-01 |
| Completed | Comparison of 23 mg Donepezil Sustained Release (SR) to 10 mg Donepezil Immediate Release (IR) in Patients Wit Alzheimer's Disease | Phase 3 | 2007-06-01 |
| Completed | Post-marketing Study of Monteplase ("Cleactor") in Patients With Acute Pulmonary Embolism Pulmonary Embolism | Phase 4 | 2007-05-01 |
| Completed | A Double-blind Study to Compare the Efficacy and Safety of Zonisamide and Carbamazepine as Monotherapy, in New Epilepsy | Phase 3 | 2007-05-01 |
| Completed | Phase 2, Parallel Group, Rollover Study of AKR-501 in Patients With ChronicITP Who Completed 28 Days of Study Idiopathic Thrombocytopenic Purpura | Phase 2 | 2007-05-01 |
| Withdrawn | A Study To Evaluate The Efficacy And Safety Of Betahistine Mesilate In The Treatment Of Patients With Vertigo Vertigo | Phase 4 | 2007-05-01 |
| Terminated | Open-Label Extension Study of Rufinamide Given as Adjunctive Therapy in Patients With Refractory Partial Seizu Refractory Partial Onset Seizures | Phase 3 | 2007-03-15 |
| Withdrawn | The Effect Of E2007 On Pharmacodynamic Responses To Levodopa Among Patients With Parkinson's Disease Who Exper Parkinson's Disease | Phase 2 | 2007-03-01 |
| Completed | Study of AKR-501 Tablets Taken Orally Once Daily for 28 Days in Patients With Chronic Idiopathic Thrombocytope Chronic Idiopathic Thrombocytopenic Purpura, Purpura, Thrombocytopenic, Idiopathic | Phase 2 | 2007-02-01 |
| Terminated | A Study of E2007 In Patients With Parkinson's Disease Parkinson's Disease | Phase 2 | 2007-02-01 |
| Completed | E7389 Administered as an IV Bolus Infusion Day 1 and Day 8 Every 3 Weeks in Pre-Treated Patients With Advanced Soft Tissue Sarcoma | Phase 2 | 2007-01-01 |
| Completed | E7389 Versus Treatment of Physician's Choice in Patients With Locally Recurrent or Metastatic Breast Cancer Breast Cancer | Phase 3 | 2006-11-01 |
| Completed | BLOOM: Behavioral Modification and Lorcaserin for Overweight and Obesity Management Obesity | Phase 3 | 2006-11-01 |
| Completed | A Study of ZYC300 Administered With Cyclophosphamide Pre-Dosing Breast Cancer, Ovarian Cancer, Prostate Cancer | Phase 1 | 2006-11-01 |
| Completed | Hippocampus Study: Comparative Effect of Donepezil 10mg/d and Placebo on Clinical and Radiological Markers Alzheimer's Disease | Phase 4 | 2006-11-01 |
| Completed | A Dose-Finding Study of E7389 in Combination With Carboplatin in Patients With Solid Tumors Cancer | Phase 1 | 2006-10-01 |
| Completed | 4-Year Open-Label Extension Phase of the Parallel-Group Study of E2007 in Patients With Refractory Partial Sei Epilepsy | Phase 2 | 2006-10-01 |
| Terminated | A Clinical Trial of Decitabine in Patients With Myelodysplastic Syndrome Myelodysplastic Syndrome | Phase 1 | 2006-10-01 |
| Terminated | A Study of E2007 as an Adjunctive Therapy in Levodopa Treated Parkinson's Disease Patients With Motor Fluctuat Parkinson's Disease | Phase 3 | 2006-10-01 |
| Completed | E7389 Versus Capecitabine in Patients With Locally Advanced or Metastatic Breast Cancer Previously Treated Wit Metastatic Breast Cancer | Phase 3 | 2006-09-20 |
| Completed | Evaluating the Efficacy and Safety of Zonisamide in the Treatment of Partial Seizures Partial Seizures | Phase 3 | 2006-09-01 |
| Completed | Efficacy, Safety, and Tolerability of E2007 in Levodopa Treated Parkinson's Disease Patients With Motor Fluctu Parkinson's Disease | Phase 3 | 2006-08-01 |
| Completed | ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsis Severe Sepsis | Phase 3 | 2006-06-01 |
| Completed | A Phase I Open Label Study of E7974 Administered on a Day 1 of 21-Day Cycle In Patients With Advanced Solid Tu Cancer, Malignant Tumors | Phase 1 | 2006-05-01 |
| Completed | A Safety Study of AQUAVAN® (Fospropofol Disodium) Injection for Sedation During Minor Surgical Procedures. Procedural Sedation | Phase 2 / Phase 3 | 2006-05-01 |
| Completed | Evaluation of Eperisone HCl in the Treatment of Acute Musculoskeletal Spasm Associated With Low Back Pain - A Muscle Spasm; Back Pain | Phase 3 | 2006-04-01 |
| Completed | An Effectiveness and Safety Study of AQUAVAN® Injection (Fospropofol Disodium) for Sedation During Flexible Br Bronchoscopy, Anesthesia | Phase 3 | 2006-04-01 |
| Completed | A Study to Investigate Use Patterns and Safety in Simulated Actual Over-the-counter (OTC) Use of Rabeprazole S Frequent Heartburn | — | 2006-04-01 |
| Completed | Safety and Efficacy Study for the Prevention of Nausea and Vomiting in Multiple Myeloma Patients Receiving Ste Multiple Myeloma | Phase 2 | 2006-03-01 |
| Completed | An Effectiveness and Safety Study of AQUAVAN® Injection (Fospropofol Disodium) for Sedation During Colonoscopy Conscious Sedation | Phase 3 | 2006-03-01 |
| Completed | A Study for Evaluating the Efficacy and Safety of Zonisamide and Lamotrigine (Lamictal) for Subjects With Refr Epilepsy | Phase 3 | 2006-03-01 |
| Completed | Rufinamide Given as Adjunctive Therapy in Participants With Refractory Partial Seizures Epilepsy | Phase 3 | 2006-02-13 |
| Completed | A 28-Week Open Label Extension Study Evaluating Safety and Tolerability of Donepezil Hydrochloride in Subjects Mild Cognitive Impairment | Phase 4 | 2006-02-01 |
| Completed | Study Investigating the Effect of E7337 on Tumor Like Lesions in Computed Tomography (CT) of the Liver Lesions of the Liver | Phase 2 / Phase 3 | 2006-02-01 |
| Completed | An Open Label Phase I Dose Escalation Study of E7080 Administered to Patients With Solid Tumors Cancer: Solid Tumors | Phase 1 | 2006-01-01 |
| Completed | A Phase 1 Open-Label Study of E7974 Administered on Days 1 and 15 of a 28-Day Cycle in Patients With Solid Mal Cancer, Malignant Tumors | Phase 1 | 2006-01-01 |
| Completed | Evaluating E7389 in Patients With Hormone Refractory Prostate Cancer With Advanced and/or Metastatic Disease S Prostate Cancer | Phase 2 | 2006-01-01 |
| Completed | EARTH 413: A Study of Aricept in Hispanic Patients With Mild to Moderate Alzheimer's Disease (AD) Alzheimer's Disease | Phase 4 | 2005-12-01 |
| Completed | Trial of Decitabine in Patients With Acute Myeloid Leukemia Acute Myeloid Leukemia | Phase 3 | 2005-11-01 |
| Completed | E3810-A001-313: Efficacy and Safety of 10 mg Rabeprazole for Treating Heartburn in Frequent Sufferers Heartburn | Phase 3 | 2005-10-01 |
| Completed | Effects of Combination Therapy With Alpha-1 Blocker (Bunazosin or Doxazosin) in the Treatment of Patients With High Blood Pressure | Phase 4 | 2005-10-01 |
| Completed | A Phase II Study of E7389 in Patients With Breast Cancer, Previously Treated With Anthracycline, Taxane and Ca Breast Cancer | Phase 2 | 2005-10-01 |
| Completed | E3810-A001-312: Efficacy and Safety of 10 mg Rabeprazole for Treating Heartburn in Frequent Sufferers Heartburn | Phase 3 | 2005-10-01 |
| Completed | Efficacy and Safety of Donepezil Hydrochloride (Aricept) in Vascular Dementia Vascular Dementia | Phase 4 | 2005-09-01 |
| Completed | A Study to Explore the Safety And Tolerability of Doses of E2007 Up to a Maximum of 8 mg In Patients With Park Parkinson's Disease | Phase 2 | 2005-09-01 |
| Completed | Treatment of Gastroesophageal Reflux Disease in 12-16 Year Old Patients With Rabeprazole Gastroesophageal Reflux Disease | Phase 2 | 2005-08-01 |
| Completed | A Phase I/Ib, Multicenter, Open-Label, Dose Escalation Study of E7080 in Patients With Solid Tumors and in Com Metastatic Melanoma | Phase 1 | 2005-07-01 |
| Completed | GPI 15715 For Sedation in the Intensive Care Unit (ICU) Setting Postoperative Sedation, Intubation, Respiration, Artificial | Phase 2 | 2005-07-01 |
| Completed | Trial of Decitabine in Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndrome Acute Myelogenous Leukemia, Myelodysplastic Syndrome | Phase 2 | 2005-07-01 |
| Completed | Study of AQUAVAN® Injection (AQUAVAN; Fospropofol Disodium) for Sedation During Colonoscopy Colonoscopy, Colonic Polyps | Phase 2 / Phase 3 | 2005-07-01 |
| Completed | An Open-Label Study of E7974 Administered on Days 1, 8, and 15 of a 28-Day Cycle and Days 1 and 8 of a 21-Day Solid Tumor Malignancies, Cancer | Phase 1 | 2005-07-01 |
| Completed | A Study of Amolimogene (ZYC101a) in Patients With High Grade Cervical Intraepithelial Lesions of the Uterine C Uterine Cervical Dysplasia | Phase 2 / Phase 3 | 2005-07-01 |
| Completed | An Open Label Dose Escalation Study Of E7080 Solid Tumor or Lymphoma | Phase 1 | 2005-07-01 |
| Completed | Safety and Efficacy of APD356 in the Treatment of Obesity Obesity | Phase 2 | 2005-06-01 |
| Completed | A Study of Decitabine Given to Adults With Advanced-Stage Myelodysplastic Syndromes Myelodysplastic Syndrome | Phase 2 | 2005-05-01 |
| Completed | A Study of E3810 With Pre- and Post-Treatment pH Monitoring in Patients With Non-Erosive Gastroesophageal Refl Non-erosive Gastroesophageal Reflux Disease | Phase 3 | 2005-05-01 |
| Completed | Pharmacokinetic Trial of Decitabine (Dacogen) Administered as a 3-hour Infusion to Patients With Acute Myeloge Leukemia | Phase 1 | 2005-04-01 |
| Completed | Study of Irofulven Plus Capecitabine in Patients With Advanced Thyroid Cancer Thyroid Cancer | Phase 2 | 2005-03-31 |
| Completed | A Study of ONTAK in Patients With Relapsed or Refractory, B-Cell Non Hodgkin's Lymphoma Lymphoma, B-Cell | Phase 2 | 2005-03-01 |
| Completed | E2007 Given as Adjunctive Therapy in Patients With Refractory Partial Seizures Epilepsy | Phase 2 | 2005-03-01 |
| Completed | Study of Decitabine for Treatment of Older Patients With Acute Myeloid Leukemia (AML) Acute Myeloid Leukemia | Phase 2 | 2005-03-01 |
| Terminated | A Study of AQUAVAN® Injection Versus Midazolam HCl for Sedation in Elderly Patients Undergoing Elective Colono Colonoscopy, Colon Polyps | Phase 2 | 2005-02-01 |
| Completed | Efficacy and Safety Study of E2007 in Migraine Prophylaxis Migraine Prophylaxis | Phase 2 | 2005-01-01 |
| Completed | Safety and Efficacy of APD356 in the Treatment of Obesity Obesity | Phase 2 | 2004-12-01 |
| Completed | Phase II Study Of E7389, Halichondrin B Analogue, In Patients With Advanced Non-Small Cell Lung Cancer, NSCLC, Non-Small-Cell Lung Carcinoma | Phase 2 | 2004-12-01 |
| Terminated | Long-Term Safety, Tolerability and Efficacy in Perampanel Treated Parkinson's Disease Patients With Motor Fluc Parkinson's Disease | Phase 2 | 2004-11-01 |
| Completed | Maintenance Intermittent Therapy for Symptomatic GERD Patients Gastroesophageal Reflux Disease | Phase 2 | 2004-10-01 |
| Terminated | A Study of AQUAVAN® Injection in the Presence of Pre-Medication in Patients Undergoing Minor Surgical Procedur Arthroscopy, Bunionectomy, Osteotomy | Phase 3 | 2004-10-01 |
| Terminated | A Study of AQUAVAN® Injection for Sedation in Elderly Patients Undergoing Flexible Bronchoscopy Flexible Bronchoscopy | Phase 3 | 2004-09-01 |
| Completed | A Study of AQUAVAN® Injection Versus Midazolam HCl for Sedation in Patients Undergoing Elective Colonoscopy Colonoscopy, Colon Polyps | Phase 3 | 2004-09-01 |
| Completed | A Study of E7389 in Advanced/Metastatic Breast Cancer Patients Breast Neoplasms | Phase 2 | 2004-09-01 |
| Completed | Study of Irofulven in Patients With Hormone-refractory Prostate Cancer Prostate Cancer | Phase 2 | 2004-06-01 |
| Completed | A Study of ONTAK and CHOP in Newly Diagnosed, Peripheral T-Cell Lymphoma Lymphoma, T-Cell, Peripheral | Phase 2 | 2004-03-14 |
| Completed | Study to Assess Safety and Efficacy of AQUAVAN® Injection for Sedation During Cardiac Catheterization Angioplasty, Coronary Catheterization | Phase 3 | 2004-02-01 |
| Completed | Study to Evaluate the Efficacy, Safety, and Tolerability of E7070 in Metastatic Breast Cancer Patients Breast Neoplasms, Metastases | Phase 2 | 2004-02-01 |
| Completed | Dosing and Safety Study of E7820 in Patients With a Malignant Solid Tumor or Lymphoma Neoplasms, Lymphoma, Malignant | Phase 1 | 2004-01-01 |
| Completed | Evaluate the Effects of GPI 1485 on Erectile Function Following Bilateral Nerve-Sparing Prostatectomy Impotence, Prostate Cancer | Phase 2 | 2003-12-01 |
| Completed | The Evaluation of the Efficacy and Safety of Donepezil Hydrochloride in Subjects With Mild Cognitive Impairmen Memory Loss | Phase 4 | 2003-12-01 |
| Completed | Study of E7389 in Patients With Advanced Solid Tumors Advanced Solid Tumors | Phase 1 | 2003-09-01 |
| Completed | Study of E7389 Administered Once Every 3 Weeks In Patients With Advanced Solid Tumors Cancer | Phase 1 | 2003-08-01 |
| Completed | Study of Irofulven in Combination With Oxaliplatin in Patients With Advanced Solid Tumors Liver Cancer | Phase 1 / Phase 2 | 2003-06-01 |
| Completed | Dose-Finding Study of E7070 in Combination With Irinotecan Cancer | Phase 1 | 2003-03-01 |
| Completed | Donepezil Hydrochloride (E2020) in Dementia Associated With Cerebrovascular Disease Dementia, Vascular | Phase 3 | 2003-03-01 |
| Completed | Safety, Tolerability, and Efficacy of Donepezil (Aricept) in Parkinson' s Disease (PD) Patients With Dementia Parkinson's Disease, Dementia | Phase 3 | 2003-03-01 |
| Completed | Study of ONTAK in Patients With B-Cell Chronic Lymphocytic Leukemia (CLL) Leukemia, Lymphocytic, Chronic | Phase 2 | 2003-03-01 |
| Completed | An Evaluation Of The Efficacy And Safety Of Donepezil Hydrochloride (E2020) In Migraine Prophylaxis Migraine Headache | Phase 2 | 2003-01-01 |
| Completed | A Study of AQUAVAN® Injection in the Presence of Pre-Medication in Patients Undergoing Elective Colonoscopy Colonoscopy, Colon Polyps | Phase 2 | 2003-01-01 |
| Completed | 2 Year Study to Evaluate the Effects of GPI 1485 on [123I]b-CIT/SPECTScanning and Clinical Efficacy in Patient Parkinson's Disease | Phase 2 | 2002-11-01 |
| Completed | Comparison of AQUAVAN® Injection to DISOPRIVAN® Injectable Emulsion for Anesthesia During Coronary Artery Surg Ischemic Coronary Artery Disease, Coronary Artery Bypass Surgery | Phase 2 | 2002-06-01 |
| Completed | A Safety, Tolerability and Efficacy Study of E7070 in Patients With Renal Cell Carcinoma Kidney Neoplasms, Carcinoma, Renal Cell, Adenocarcinoma, Renal Cell | Phase 2 | 2002-05-01 |
| Completed | Evaluation of Efficacy, Safety and Tolerability of Targretin Capsules in Patients With Advanced or Metastatic Non-small Cell Lung Cancer | Phase 3 | 2002-05-01 |
| Completed | Dose Response Study of Zonegran in Patients With Newly Diagnosed Epilepsy Epilepsy, Complex Partial | Phase 3 | 2002-02-01 |
| Completed | A Safety and Efficacy Study of Intravenous E5564 in Patients With Severe Sepsis Sepsis, Shock, Septic, Sepsis Syndrome | Phase 2 | 2001-10-01 |
| Completed | Study of ONTAK® to Treat Cutaneous T-Cell Lymphoma (CTCL) Lymphoma, T-Cell, Cutaneous | Phase 4 | 2001-05-01 |
| Completed | Efficacy and Safety of Aricept in the Treatment of Severe Alzheimer's Disease Alzheimer's Disease, Dementia | Phase 3 | 2001-01-01 |
| Completed | Phase II Study of ONTAK in Previously Treated Patients With Low-grade Non-Hodgkin's Lymphoma (NHL) Non-Hodgkin's Lymphoma, Lymphoma, B-cell, Lymphoma, Low-grade | Phase 2 | 2000-05-01 |
| Completed | Irofulven Compared With Fluorouracil in Treating Patients With Pancreatic Cancer Pancreatic Cancer | Phase 3 | 2000-01-01 |
| Completed | Study of ONTAK (Denileukin Diftitox) in Previously Treated Cutaneous T-Cell Lymphoma Patients Lymphoma, T-Cell, Cutaneous, Mycosis Fungoides, Sezary Syndrome | Phase 4 | 1995-09-01 |
| Completed | Study of ONTAK (Denileukin Diftitox) in Cutaneous T-Cell Lymphoma (CTCL) Patients Lymphoma, T-Cell, Cutaneous, Mycosis Fungoides, Sezary Syndrome | Phase 4 | 1995-06-01 |
| Available | An Extended Access Program (EAP) for Participants Who Have Completed Rufinamide Study E2080-G000-303 Lennox Gastaut Syndrome | — | — |
| No Longer Available | Access Program With Denileukin Diftitox for the Treatment of Patients Currently Receiving Treatment With Comme Cancer | — | — |
| Approved For Marketing | Expanded Access Program With Lenvatinib for the Treatment of Differentiated Thyroid Cancer in Brazil Thyroid Cancer | — | — |
| Approved For Marketing | An Expanded Access Program With Lenvatinib for the Treatment of Radioiodine-Refractory Differentiated Thyroid Differentiated Thyroid Cancer | — | — |
| Available | Extended Access Program With Lorcaserin For The Treatment of Dravet Syndrome and Other Refractory Epilepsies Epilepsies, Myoclonic, Drug Resistant Epilepsy | — | — |
| No Longer Available | An Extended Access Program for Perampanel Partial Onset Seizures | — | — |
| No Longer Available | An Extended Access Program (EAP) for Perampanel Primary Generalized Tonic-Clonic or Partial Onset Seizures, Lennox Gastaut Syndrome | — | — |
| Completed | Evaluation of Efficacy, Safety and Tolerability of Targretin Capsules in Patients With Advanced or Metastatic Non-small Cell Lung Cancer | Phase 3 | — |