Clinical Trials Directory

Trials / Terminated

TerminatedNCT04572243

A Study of Lorcaserin as Adjunctive Treatment in Participants With Dravet Syndrome

A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Study With Open-Label Extension Phase of Lorcaserin as Adjunctive Treatment in Subjects With Dravet Syndrome

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
22 (actual)
Sponsor
Eisai Inc. · Industry
Sex
All
Age
2 Years
Healthy volunteers
Not accepted

Summary

The primary purpose of the study is to demonstrate that lorcaserin has superior efficacy compared to placebo on percent change in frequency of convulsive seizures per 28 days in participants with Dravet syndrome.

Conditions

Interventions

TypeNameDescription
DRUGPlaceboPlacebo matching to lorcaserin oral tablet, administered as oral suspension.
DRUGLorcaserinLorcaserin oral tablet, administered as oral suspension.

Timeline

Start date
2020-09-23
Primary completion
2024-08-15
Completion
2024-08-15
First posted
2020-10-01
Last updated
2025-10-08
Results posted
2025-10-08

Locations

30 sites across 2 countries: United States, Canada

Regulatory

Source: ClinicalTrials.gov record NCT04572243. Inclusion in this directory is not an endorsement.