NCT03968328

Time From Onset of Fever to Administration of Antibiotics in Neutropenic Fever Patients

The Prognostic Value of the Time From Onset of Fever to Administration of Antibiotics in Neutropenic Fever Patients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 315 (actual)
• Sponsor: M.D. Anderson Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This trial uses an interview and a survey to gather information from cancer patients about the onset of their fever and the administration of antibiotics. Collecting information from patients may help doctors to assess the relationship between time to antibiotic administration and inhospital cause specific death, intensive care unit admission, hospital length of stay, and positive blood cultures.

Detailed description

PRIMARY OBJECTIVES: I. To assess the prognostic value of the length of time between the time onset of fever and first antibiotic administration on cause specific 14 day mortality rate. SECONDARY OBJECTIVES: I. To assess the associations of the length of time between the time onset of fever and first antibiotic administration with intensive care unit (ICU) admission, ICU length of stay, length of hospitalization and percentage of patients with positive blood cultures. OUTLINE: Patients respond to a survey and participate in an interview with study staff about their fever and when they started feeling unwell.

Conditions

• Febrile Neutropenia
• Fever

Interventions

Type	Name	Description
OTHER	Interview	Take part in interview
OTHER	Survey Administration	Respond to survey

Timeline

• Start date: 2015-06-19
• Primary completion: 2023-01-17
• Completion: 2023-01-17
• First posted: 2019-05-30
• Last updated: 2023-07-21

Locations

1 site across 1 country: United States