Clinical Trials Directory

Trials / Completed

CompletedNCT03656939

A Safety Study For Prevenar 13 Among Chinese Children

AN OBSERVATIONAL SAFETY STUDY FOR PREVENAR 13 AMONG CHINESE CHILDREN

Status
Completed
Phase
Study type
Observational
Enrollment
21,240 (actual)
Sponsor
Pfizer · Industry
Sex
All
Age
1 Month – 24 Months
Healthy volunteers
Not accepted

Summary

This is an observational study based on a population-based EHR database.

Detailed description

This observational study based on a population-based EHR database in Yinzhou district of Ningbo city in China is to estimate incidence rates of seizures (including febrile seizures), urticaria and angioedema, apnea, and fever among Chinese children after receiving Prevenar 13. In addition, a validation study including validation of International classification of diseases, tenth revision (ICD-10) codes or ICD-10 code based algorithm for identifying all safety outcomes of interest and a prospective cohort study in a sub-population of the main study will be conducted in order to offset the potential biased results from the main study because of potential misclassification of the safety outcomes of interest due to miscoding and/or undercoding of ICD-10 codes used to identify these safety outcomes in the EHR database.

Conditions

Timeline

Start date
2018-08-01
Primary completion
2020-07-31
Completion
2020-07-31
First posted
2018-09-04
Last updated
2021-08-27
Results posted
2021-08-27

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT03656939. Inclusion in this directory is not an endorsement.