| Not Yet Recruiting | 4AP for Carpal Tunnel Syndrome (CTS) NCT06294821 | John Elfar | Phase 2 |
| Not Yet Recruiting | Median Nerve Cross-Sectional Area and Body Weight in Carpal Tunnel Syndrome NCT07508397 | Kayseri City Hospital | — |
| Not Yet Recruiting | Effects of Neurodynamic and Carpal Bone Mobilization in Mild-to-Moderate Carpal Tunnel Syndrome NCT07359274 | Kutahya Health Sciences University | N/A |
| Not Yet Recruiting | Efficacy of Combining Ultrasound-Guided Needle Release of Transverse Carpal Ligament and Median Nerve Dextrose NCT07324005 | Shin Kong Wu Ho-Su Memorial Hospital | N/A |
| Recruiting | A Study to See Whether Taking a Mix of Vitamins Can Help Adults Recover Better After Surgery for Carpal Tunnel NCT07312123 | Hospital Universiti Sains Malaysia | N/A |
| Not Yet Recruiting | Acute Effects of Warm Whirlpool Bath Therapy on Forearm and Hand Muscle Stiffness and Pain in Carpal Tunnel Sy NCT07252960 | Erzurum Technical University | N/A |
| Recruiting | Ultrasound-Guided Carpal Tunnel Infiltration: Comparison Between the Manual Method and a Robot-Assisted Method NCT07334964 | Centre Hospitalier Régional d'Orléans | N/A |
| Recruiting | High-Intensity Laser Therapy in Carpal Tunnel Syndrome: Clinical, Sonographic, and Electrophysiological Outcom NCT07414069 | Ankara City Hospital Bilkent | N/A |
| Completed | Effect of Russian Current on Hand Grip Strength and Functional Outcome After Carpal Tunnel Release NCT07166029 | Cairo University | N/A |
| Completed | Comparison of Injection Techniques in Carpal Tunnel Syndrome NCT07105540 | Ankara Etlik City Hospital | Phase 4 |
| Not Yet Recruiting | Effect of Myofascial Release Versus Acupressure on Carpal Tunnel Syndrome in Postnatal Period NCT07086846 | Cairo University | N/A |
| Not Yet Recruiting | Different Treatment Approaches for Carpal Tunnel Syndrome NCT07048379 | Sakarya University | N/A |
| Not Yet Recruiting | Topical Cannabidiol for Treating Carpal Tunnel Syndrome NCT06108349 | University of Virginia | Phase 2 |
| Recruiting | Symptom Distribution and Pain Sensitization in Carpal Tunnel Syndrome NCT07114913 | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | — |
| Completed | Effect of Exercise on Ultrasound SWV in CTS Patients NCT07281573 | University Medical Centre Ljubljana | N/A |
| Active Not Recruiting | Effects of Aquatic Therapy Versus Neuro-dynamic Technique for the Treatment of Carpal Tunnel Syndrome Patient NCT06905769 | Superior University | N/A |
| Recruiting | Added Value of Ultrasonography in the Diagnosis, Management, and Follow-Up of Carpal Tunnel Syndrome NCT06834061 | Kafrelsheikh University | — |
| Completed | Gabapentin and Neural Mobilization Pain Reduction Effect Compared to Only Gabapentine NCT06778798 | Universidad Europea de Madrid | Phase 4 |
| Completed | Pain Reduction Caused by the Combined Treatment of Physiotherapy, Oral Gabapentin and Oral Ibuprofen Arginine. NCT06781489 | Universidad Europea de Madrid | Phase 4 |
| Completed | Ibuprofen Arginine and Neural Mobilization Versus Ibuprofen Arginine in the Treatment of Carpal Tunnel Syndrom NCT06778759 | Universidad Europea de Madrid | Phase 4 |
| Recruiting | Efficacy of Red Kinesiology Tape on Carpal Tunnel-Like Symptoms and Performance in Esports Gamers NCT06757062 | University of Nevada, Las Vegas | N/A |
| Not Yet Recruiting | Thenar Muscle Ultrasound in CTS Evaluation NCT06730724 | Beylikduzu State Hospital | — |
| Completed | Investigating the Effect of Carpal Tunnel Syndrome on Activity and Participation NCT06635109 | Kutahya Health Sciences University | — |
| Recruiting | Small Nerve Fiber Activity in Patients with Carpal Tunnel Syndrome Assessed Via Quantitative Sensory Testing NCT06550284 | Brooke Army Medical Center | N/A |
| Recruiting | Comparison of the Efficacy of Ultrasound-Guided Corticosteroid Injection and Paraffin Therapy in Carpal Tunnel NCT06658886 | Beylikduzu State Hospital | — |
| Completed | Pain Phenotype in Patients With Carpal Tunnel Syndrome NCT06635200 | Kutahya Health Sciences University | — |
| Completed | Is Ultrasound-Guided Steroid Injection Less Effective in Carpal Tunnel Syndrome Patients with Bifid Median Ner NCT06657612 | Beylikduzu State Hospital | — |
| Recruiting | Effectiveness of Desensitisation and Pain Neuroscience Education in Patients With Carpal Tunnel Syndrome With NCT06635213 | Kutahya Health Sciences University | N/A |
| Recruiting | Comparison of the Efficacy of Peloid Therapy and Paraffin Treatment in Carpal Tunnel Syndrome NCT06405438 | Beylikduzu State Hospital | — |
| Not Yet Recruiting | Effectiveness of Audiovisual Versus Written Postoperative Instructions for Patients Undergoing Minor Hand Proc NCT06582550 | McGill University Health Centre/Research Institute of the McGill University Health Centre | N/A |
| Recruiting | Efficacy of Steroid Injection in Patients With Bifid Median Nerve Diagnosed Carpal Tunnel Syndrome NCT06599086 | Yunus Burak Bayır | N/A |
| Recruiting | ATTR Cardiac Amyloidosis in a Selected Population NCT06458374 | Helse Møre og Romsdal HF | — |
| Recruiting | Sonographic Examination of Median Nerve Variations NCT06538779 | Yunus Burak Bayır | — |
| Completed | Bilateral vs. Unilateral Neuromobilization in Carpal Tunnel Syndrome NCT06554405 | Gazi University | N/A |
| Not Yet Recruiting | Effect of Acupressure on Carpal Tunnel Syndrome in Pregnant Women NCT06555926 | Cairo University | N/A |
| Recruiting | Ozone Therapy in Patients With Carpal Tunnel Syndrome NCT06469931 | Firat University | N/A |
| Not Yet Recruiting | In Patients With Carpal Tunnel Syndrome, Median Nerve Conduction is Evaluated After Nerve Mobilizations NCT06399484 | Universidad de Zaragoza | N/A |
| Completed | Comparing Efficacies of Median Nerve Hydrodissection With Dexamethasone and Dextrose in Carpal Tunnel Syndrome NCT06400433 | Istanbul University - Cerrahpasa | N/A |
| Completed | WALANT Versus Axillary Brachial Plexus Block in Carpal Tunnel Release NCT06040840 | CMC Ambroise Paré | N/A |
| Recruiting | Effect of Blood Flow Restriction on Pain Perception, Grip Strength and Nerve Conductivity in CTS Patients. NCT06574841 | Cairo University | N/A |
| Recruiting | Carpal Arch Space Augmentation (CASA) Clinical Trial NCT06208709 | University of Arizona | N/A |
| Completed | Dry Needling and Rehabilitatin Carpal Tunnel Syndrome NCT06358326 | Karabuk University | N/A |
| Completed | COMET-AOA: Median Nerve Stiffness in Mild-Moderate CTS With OMT & Conservative Therapy NCT06150443 | Kettering Health Network | N/A |
| Completed | The Effect and Safety of Recombinant Fibroblast Growth Factor-1 for Carpal Tunnel Syndrome NCT06328166 | Tri-Service General Hospital | N/A |
| Withdrawn | Surgical Dressings After Endoscopic Carpal Tunnel Release NCT04070924 | Chris Grandizio | N/A |
| Recruiting | Orthopaedic Specimen Pathology and Early Diagnosis of ATTR Cardiopathy (ATTR-ORTHO) NCT06367842 | Institut Mutualiste Montsouris | — |
| Recruiting | Effects of Pain Neuroscience Education and Standard Rehabilitation Regime in Patients of Carpal Tunnel Syndrom NCT06509633 | Riphah International University | N/A |
| Active Not Recruiting | Registry of the Patient Experience for Carpal Tunnel Release NCT06071468 | Sonex Health, Inc. | — |
| Recruiting | Comparison of Ultrasound-Guided Injection With Median Nerve Decompression Surgery in Carpal Tunnel Syndrome NCT06243848 | Afyonkarahisar Health Sciences University | N/A |
| Recruiting | Platelet-Rich Plasma Injection Versus Hydrodissection in the Treatment of Carpal Tunnel Syndrome NCT06368505 | Osama Ahmed Elshafei | N/A |
| Recruiting | In Patients With Carpal Tunnel Syndrome, Median Nerve Conduction is Evaluated After Moving the Wrist Bones NCT06399380 | Universidad de Zaragoza | N/A |
| Unknown | Wide Awake Open Carpal Tunnel Release With or Without a Tourniquet NCT06172400 | Region Skane | N/A |
| Completed | Comparison of Different Treatment Approaches in Carpal Tunnel Syndrome NCT06238440 | Muğla Sıtkı Koçman University | N/A |
| Completed | Hydrodissection in Carpal Tunnel Syndrome NCT07207460 | Ankara City Hospital Bilkent | N/A |
| Recruiting | Association Between Radial Artery Intervention and Development of Neuropathy in the Hand - A Prospective Study NCT05365282 | Aarhus University Hospital Skejby | — |
| Recruiting | Ultrasound-Guided Curved Needle Thread Carpal Tunnel Release: Efficacy and Safety of a Single-Center, Single-A NCT06440070 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | N/A |
| Completed | Hereditary Transthyretin Amyloidosis Polyneuropathy in Patients With Carpal Tunnel Syndrome in Russia NCT06414746 | AstraZeneca | — |
| Completed | Impact of Walking Aids on the Occurrence of Carpal Tunnel Syndrome in Rehabilitation NCT06186284 | Centre Hospitalier Valida | N/A |
| Completed | Effect of Mechanical Interface Mobilization Technique on Pain and Functional Status in Carpal Tunnel Syndrome NCT06598748 | Riphah International University | N/A |
| Completed | Median Nerve Stenosis in Carpal Tunnel Syndrome NCT05861349 | Jakub Antczak | — |
| Unknown | Efficacy of Extracorporeal Shock Wave Therapy on Carpal Tunnel Syndrome Post Mastectomy Lymphedema NCT06131515 | Cairo University | N/A |
| Completed | Investigation of the Efficiency of Radial Extracorporeal Shock Wave Therapy at Different Pulses in Carpal Tunn NCT06321276 | Ahi Evran University Education and Research Hospital | N/A |
| Completed | Correlation of Different Ultrasonographic Indices With Clinical Parameters in Carpal Tunnel Syndrome NCT06115187 | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | — |
| Completed | Dextrose, Steroid, PRP: Choosing the Right Injection for CRS Relief; a RCT NCT06349824 | Sheikh Zayed Medical College | Phase 4 |
| Completed | Ultrasound-Guided 5% Dextrose Injection for Carpal Tunnel Syndrome NCT06349265 | Kastamonu University | Phase 4 |
| Completed | Investigation of the Relationship Between Pain Sensitization and Diagnostic Parameters in Carpal Tunnel Syndro NCT06043141 | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | — |
| Unknown | Cross-Cultural Adaptation and Psychometric Validation of the Turkish Version of Atroshi-Lyrén 6-item Symptoms NCT05970692 | Ilke KARA | — |
| Recruiting | Ultrasound-guided Dextrose Injection Versus Dextrose With Methylprednisolone in Carpal Tunnel Syndrome NCT06045013 | General and Veteran Hospital Croatian Pride Knin | Phase 3 |
| Completed | Effect of Different Doses of US in the Treatment of CTS NCT05863546 | Cairo University | N/A |
| Unknown | Multimodal Approach of Electrotherapy Versus Nerve Flossing Technique in Patient With Carpal Tunnel Syndrome NCT05164237 | October 6 University | N/A |
| Completed | Objective Evaluation of the Scratch Collapse Test With Dynamometer, a Prospective Multicenter Trial. NCT05989373 | Clinique Saint Jean, France | N/A |
| Unknown | The Evaluation for Fu's Subcutaneous Needling (FSN) in Carpal Tunnel Syndrome. NCT05627349 | China Medical University Hospital | N/A |
| Active Not Recruiting | Shock Wave on Pillar Pain After Carpal Tunnel Release in Hand Burn NCT06371885 | Cairo University | N/A |
| Completed | Effects of Body Structures and Function on Actıvıty and Partıcıpatıon in Patıents wıth Carpal Tunnel Syndrome NCT05983614 | Kutahya Health Sciences University | — |
| Unknown | The Effect of Low-Level Laser Therapy in Carpal Tunnel Syndrome NCT06248541 | Medical University of Graz | N/A |
| Unknown | Refining the Interpretation of the Tinel's Sign for Carpal Tunnel Syndrome NCT05969093 | Ahram Canadian University | — |
| Unknown | Median Nerve Function During Phalen's Test NCT05965791 | Ahram Canadian University | — |
| Unknown | Predicting Nociplastic Pain in Carpal Tunnel Syndrome Through Quantitative Sensory Testing NCT05959954 | Ahram Canadian University | — |
| Unknown | Corticosteroids in Carpal Tunnel Syndrome. Prospective Randomised Controlled Non-inferiority Study NCT06272682 | Hospital Italiano de Buenos Aires | N/A |
| Unknown | Predictive Value of Baseline CTQ-SSS Scores for Progression to Carpal Tunnel Release Surgery: A Cohort Study NCT05838963 | Ahram Canadian University | — |
| Recruiting | Validity and Reliability of Thai Version Clinical Questionnaire for Diagnosis of Carpal Tunnel Syndrome NCT06239259 | Siriraj Hospital | — |
| Active Not Recruiting | Hand10 Questionnaire in Individuals With Carpal Tunnel Syndrome NCT05916456 | Hasan Kalyoncu University | — |
| Unknown | Combined Physical and Psychological Intervention in Carpal Tunnel Syndrome Patients With Nociplastic Pain NCT05915611 | Ahram Canadian University | N/A |
| Recruiting | Effect of Cooling Therapy for Post-Operative Pain in Open Carpal Tunnel Release NCT05783245 | University of Chicago | N/A |
| Completed | Mulligan Mobilization With Arm Movement in CTS Patients NCT07042542 | Beste Gebologlu | N/A |
| Completed | Thermal and Pulsed Ultrasound for Carpal Tunnel Syndrome NCT05838807 | Ahram Canadian University | N/A |
| Unknown | Hand Function Tests in Carpal Tunnel Syndrome: A Cross-sectional Study NCT05838820 | Ahram Canadian University | — |
| Unknown | Mechanisms of Neurodynamic Treatments NCT05859412 | University of Oxford | N/A |
| Completed | Effectiveness Transfer Energy Capacitive and Resistive Therapy in Patients With Carpal Tunnel Syndrome NCT06451094 | Ankara City Hospital Bilkent | N/A |
| Unknown | Role of Inflammation in Carpal Tunnel Syndrome NCT05852288 | Ahram Canadian University | — |
| Completed | Comparison of %5 Dextrose and Betamethasone Injections in Patients With Carpal Tunnel Syndrome NCT06360510 | Gaziler Physical Medicine and Rehabilitation Education and Research Hospital | — |
| Completed | The Effectiveness of Stretching and Orthoses in Individuals With Carpal Tunnel Syndrome NCT05838989 | Ahram Canadian University | N/A |
| Unknown | Validity and Reliability of CTQ-SSS in Carpal Tunnel Syndrome. NCT05838976 | Ahram Canadian University | — |
| Completed | Effect of Neurodynamic Exercises and Education Program Applied With Virtual Reality Assisted Telerehabilitatio NCT05821127 | Istanbul University | N/A |
| Completed | Evaluation of Carpal Tunnel Syndrome in Pregnancy NCT05839769 | Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization | — |
| Completed | The Reliability And Validity Of A Smartphone App NCT05819242 | Kirsehir Ahi Evran Universitesi | — |
| Unknown | Effect of Neurodynamic Mobilization on Median Nerve Conduction Velocity in Carpal Tunnel Syndrome NCT05788471 | Cairo University | N/A |
| Completed | Effect of Low Level Laser Therapy Versus Pulsed Ultrasound NCT05904561 | Egymedicalpedia | N/A |
| Unknown | Effectiveness of an Invasive Physical Therapy Protocol in Carpal Tunnel Syndrome: Randomized Controlled Clinic NCT05527743 | Universitat Internacional de Catalunya | N/A |
| Unknown | Evaluation of a Conservative Treatment by Nocturnal Wrist Orthosis in the Non-surgical Management of Carpal Tu NCT05483218 | Centre Hospitalier Saint Joseph Saint Luc de Lyon | N/A |
| Recruiting | The Relationship Between Ultrasonographic Findings and Sleep Quality in Carpal Tunnel Syndrome NCT05742776 | Afyonkarahisar Health Sciences University | — |
| Completed | Effectiveness of Manual Therapy and Extracoropral Shock Wave Therapy in Patients With Carpal Tunnel Syndrome NCT07074509 | Tanta University | N/A |
| Completed | Multicenter Prospective Trial of Office-based Carpal Tunnel Release With Ultrasound Guidance (ROBUST) NCT05675046 | Sonex Health, Inc. | N/A |
| Recruiting | Effect of Night-time and Full-time Splinting for Carpal Tunnel Syndrome NCT05637294 | Tampere University Hospital | N/A |
| Unknown | The Effectiveness of Extracorporeal Shock Wave Therapy for Management of Carpal Tunnel Syndrome NCT05681663 | Ahi Evran University Education and Research Hospital | N/A |
| Completed | Ultrasound Guided Median Nerve Hydrodissection Using Dextrose NCT05725460 | Iraqi Board of medical specialties | N/A |
| Completed | Ultrasound Guided Activated and Non Activated Platelet Rich Plasma Injection Versus Hydro Dissection by Steroi NCT06249503 | Ain Shams University | Phase 4 |
| Completed | Neurodynamic Sequencing in Patients With Carpal Tunnel Syndrome NCT05905107 | Riphah International University | N/A |
| Unknown | Statistically Analysis of Carpal Tunnel Syndrome Diagnosis NCT05584839 | İSMAİL CEYLAN | — |
| Unknown | Hydrodissection in Carpal Tunnel Syndrome NCT06188390 | Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation | N/A |
| Completed | The Effect of High-intensity Laser Therapy in Patients With Carpal Tunnel Syndrome. NCT05678595 | Necmettin Erbakan University | N/A |
| Completed | Effectiveness of Carpal Ligament Self-myofascial Stretching in Carpal Tunnel Syndrome NCT06229249 | King Saud University | N/A |
| Completed | Evaluation of the Acute Effect of Kinesio Taping by Ultrasonography NCT05475197 | Mersin University | N/A |
| Completed | Dual Task During Resistance Training in CTR NCT05592184 | University of Valencia | — |
| Completed | Dual Task During Exercise for Carpal Tunnel Release NCT05593952 | University of Valencia | N/A |
| Completed | Sleep Quality in Carpal Tunnel Syndrome, Splinting and Kinesiotaping NCT06514625 | Konya Beyhekim Training and Research Hospital | N/A |
| Completed | Low Intensity Ultrasound in Patients With Carpal Tunnel Syndrome NCT05637684 | Cairo University | N/A |
| Unknown | Comparison of Low-intensity Laser and ESWT in Carpal Tunnel Syndrome NCT05589805 | Abant Izzet Baysal University | N/A |
| Completed | Correlation Between Palmaris Longus Muscle and Carpel Tunnel Syndrome NCT05578963 | Bahria University | — |
| Completed | Effect of the Kinesiotaping on paın, Function and electrophysiologıcal Findings in Patient With Carpal Tunnel NCT05592067 | Kirsehir Ahi Evran Universitesi | N/A |
| Unknown | Dexmedetomidine Versus Triamcinolone Treatment in Carpal Tunnel Syndrome NCT05624866 | Assiut University | N/A |
| Completed | A Study of Fisetin to Treat Carpal Tunnel Syndrome NCT05416515 | Peter C. Amadio, M.D. | Phase 2 |
| Completed | Investigation of the Efficacy of Virtual Reality Mediated Neurodynamic Exercises in Carpal Tunnel Syndrome NCT05563909 | Istanbul University | N/A |
| Active Not Recruiting | An Absorbable Suture Versus a Non-absorbable Suture in Carpal Tunnel Release, a Randomized Controlled Trial NCT05503719 | Kuopio University Hospital | N/A |
| Active Not Recruiting | aDjunct bicarbonatE in Local anaesthesIa for CarpAl Tunnel rElease (DELICATE) NCT05328180 | Kuopio University Hospital | N/A |
| Recruiting | Carpal Tunnel Release Under Local Anaesthesia With or Without Distal Median Nerve Block NCT05372393 | Kuopio University Hospital | N/A |
| Completed | Efficacy of Ultrasound-Guided Hydrodissection in Carpal Tunnel Syndrome NCT05222126 | Afyonkarahisar Health Sciences University | N/A |
| Completed | Are There Differences in Postoperative Pain Between Bupivacaine and Lidocaine for Carpal Tunnel Release? NCT05697276 | Hospital Italiano de Buenos Aires | N/A |
| Completed | Hydrodissection Between Normal Saline and a Combination of Triamcinolone Acetonide, Normal Saline, and Lidocai NCT05577676 | Bangladesh College Of Physicians And Surgeons (BCPS) | N/A |
| Completed | Effects of Upper Extremity Manual Lymphatic Drainage on Symptom Severity, Hand Functions, Electrophysiological NCT05490420 | Istanbul Medeniyet University | N/A |
| Completed | Clinical Investigation on Safety, Performance and Effectiveness of Sono-instruments NCT05435950 | Spirecut | N/A |
| Completed | Trial of Ultrasound Guided Carpal Tunnel Release Versus Traditional Open Release (TUTOR) NCT05405218 | Sonex Health, Inc. | N/A |
| Withdrawn | Turkish Version of the Hand20 Questionnaire With Carpal Tunnel Syndrome NCT05263128 | Hasan Kalyoncu University | — |
| Active Not Recruiting | Comparison of the Efficacy of Different Treatment Methods in Patients With Carpal Tunnel Syndrome NCT05475808 | Abant Izzet Baysal University | Phase 4 |
| Completed | Comparison of Two Techniques for the Treatment of Carpal Tunnel Syndrome NCT05468814 | Hospital Universitario Reina Sofia de Cordoba | N/A |
| Terminated | Comparative Study of Two Incision vs. Mini Open Carpal Tunnel Release NCT05325567 | University of Louisville | N/A |
| Active Not Recruiting | Postoperative Care After Carpal Tunnel Release Using Short Educational Videos NCT06647719 | Carilion Clinic | N/A |
| Completed | A Comparison of Tissue Adhesive Material and Suture as Wound-closure Techniques Following Carpal Tunnel Decomp NCT05747989 | University of Split, School of Medicine | N/A |
| Unknown | Efficacy of Extracorporeal Shock Wave Therapy in Carpal Tunnel Syndrome NCT05314777 | University of Beykent | N/A |
| Unknown | BotulInum Toxin Type A for Peripheral Neuropathic Pain in subjEcts With Carpal Tunnel Syndrome NCT05411900 | Francesco Bono | Phase 2 |
| Unknown | New 3D Printed Wrist Orthosis NCT05597930 | TOPMED | N/A |
| Recruiting | abSorbable vErsus Non-absorbable SuturEs for Wound Closure in Carpal Tunnel Release NCT05431101 | Gelre Hospitals | N/A |
| Unknown | Effects of Kinesiotaping With and Without Active Release Technique in Patients With Carpal Tunnel Syndrome NCT05354011 | Riphah International University | N/A |
| Active Not Recruiting | A Norwegian Trial Comparing Treatment Strategies for Carpal Tunnel Syndrome NCT05306548 | Diakonhjemmet Hospital | Phase 4 |
| Completed | Comparison of Conventional Versus Transverse Mini-Incision Technique for Carpal Tunnel Release NCT07018011 | RESnTEC, Institute of Research | N/A |
| Completed | Effectiveness of Ultrasound Guided Hydro-dissection of Median Nerve in Carpal Tunnel Syndrome NCT05204992 | Ain Shams University | N/A |
| Completed | Dexmedetomidine Versus Hyalase Treatment of Carpal Tunnel Syndrome NCT05280223 | Assiut University | N/A |
| Recruiting | The ACTS Trial: N-acetylcysteine (NAC) and Night-splinting as a Non-operative Treatment for Carpal Tunnel Synd NCT04460521 | Emily Krauss | Phase 4 |
| Completed | Effect of Out of Plane and In Plane Injection Techniques in Patients With Carpal Tunnel Syndrome NCT05343351 | Istanbul University - Cerrahpasa | N/A |
| Completed | Clinical and Electrophysiological Evaluation of the Effectiveness for Manual Lymphatic Drainage NCT05394870 | Selcuk University | N/A |
| Unknown | Effect of Phonophoresis With Vitamin B12 on CTS NCT05260593 | October 6 University | N/A |
| Completed | Comparison of Flexor Retinaculum Stretch and Carpal Mobilizations in Patients With Carpal Tunnel Syndrome. NCT05863780 | Riphah International University | N/A |
| Completed | Safety and Efficacy of Carpal Stim in Treating Carpal Tunnel Syndrome NCT05497037 | GiMer Medical | N/A |
| Completed | Comparison of Efficacy Between Conservative Versus Operative Management of Carpel Tunnel Syndrome NCT06060314 | Combined Military Hospital Abbottabad | N/A |
| Unknown | Appropriateness of Carpal Tunnel Syndrome Management Compared With the AAOS Appropriate Use Criteria NCT05275816 | Hamad Medical Corporation | — |
| Completed | Evaluation of Joint Position Sense in Carpal Tunnel Syndrome NCT06048861 | Pamukkale University | N/A |
| Completed | The Effect of Splints in Pregnant Women With Carpal Tunnel Syndrome NCT06131996 | Mardin Artuklu University | N/A |
| Completed | Telerehabilitation in Carpal Tunnel Syndrome NCT05184413 | Hospital Clínico La Florida | N/A |
| Withdrawn | The Effect of Theraworx Foam in Carpal Tunnel Syndrome NCT04017390 | John Fowler | Phase 4 |
| Completed | Comparıson Of Electromyography Results Before And After Vıtamın D Treatment In Patıents Wıth Carpal Tunnel Syn NCT06282640 | Dr. Ayşe Güç | Phase 4 |
| Completed | Effects Of Power Ball Exercises In Addition To Routine Physical Therapy In Patients With Carpal Tunnel Syndrom NCT05460026 | University of Lahore | N/A |
| Completed | Sonographic Measurement of Intraneural Blood Flow in the Median Nerve NCT05057754 | University of Southern California | N/A |
| Unknown | Vitamin B12 and Dextrose for Median Nerve Hydrodissection NCT05423028 | National Cheng-Kung University Hospital | N/A |
| Completed | Effectiveness of Mirror Therapy in Patients With Carpal Tunnel Syndrome NCT05115396 | University of Valencia | N/A |
| Unknown | Local Injection of Steroid VS.Glucose 5% in Carpal Tunnel Syndrome NCT05496764 | Assiut University | Phase 4 |
| Completed | Comparing a Modified Mini-incision Approach Versus the Conventional Approach for Carpal Tunnel Release NCT06114823 | Mansoura University | N/A |
| Completed | Short Term Efficacy of 5% Dextrose Injection With Ultrasound Guided Nerve Hydrodissection Method in CTS NCT06189651 | Istanbul Physical Medicine Rehabilitation Training and Research Hospital | N/A |
| Completed | Social and Cognitive Factors in Carpal Tunnel Syndrome NCT05023603 | Hospital Clínico La Florida | — |
| Terminated | PRP as Adjuvant Treatment to CTR for Severe CTS Tunnel Syndrome NCT04811287 | Michael Fredericson, MD | N/A |
| Unknown | Soft Tissue Massage Along With Mobilization Technique on Symptoms and Functional Status of Carpal Tunnel Syndr NCT05466162 | Dow University of Health Sciences | N/A |
| Completed | Minimal Invasive Carpal Tunnel Release With the Novel Device NCT05067205 | Kaohsiung Medical University | N/A |
| Unknown | Role of Ultrasonography in the Diagnosis of Carpal Tunnel Syndrome NCT04976998 | Sohag University | — |
| Completed | Effect of Kinesiotaping and Night Splinting in Patients With Carpal Tunnel Syndome NCT04993703 | Hacettepe University | N/A |
| Completed | The Effect of Different Molecular Weight of HA for Carpal Tunnel Syndrome NCT04766918 | Tri-Service General Hospital | N/A |
| Completed | Dexmedetomidine Versus Triamcinolone Treatment of Carpal Tunnel Syndrome NCT04961281 | Assiut University | N/A |
| Completed | Carpal Tunnel Syndrome, Right/Left Judgement NCT04967144 | Bozyaka Training and Research Hospital | — |
| Terminated | Carpal Tunnel Release Using Ultrasound NCT05031338 | Sonex Health, Inc. | — |
| Completed | Extra Corporeal Shock Wave Versus Kinesio Tape in Carpal Tunnel Syndrome NCT05405647 | Cairo University | N/A |
| Completed | Does a Different Local Anesthetic Improve Pain After Carpal Tunnel Release? NCT04833777 | University of Saskatchewan | N/A |
| Completed | The Effect of ESWT in Carpal Tunnel Syndrome NCT04896398 | Istanbul University | N/A |
| Completed | High Intensity Laser Therapy in Carpal Tunnel Syndrome NCT04949373 | Afyonkarahisar Health Sciences University | N/A |
| Completed | Reliability And Validity Of Urdu Version Of Disabilities Of The Arm, Shoulder And Hand Questionnaire NCT05411068 | Riphah International University | — |
| Completed | Reliability And Validity Of Urdu Version Of Boston Carpal Tunnel Syndrome Questionnaire NCT05207566 | Riphah International University | — |
| Completed | Impact of a Conservative Treatment in the Waiting List for Carpal Tunnel Syndrome Surgery. NCT05130931 | Universidad de Zaragoza | N/A |
| Unknown | The Effect of Acupuncture and Laser Acupuncture for Carpal Tunnel Syndrome NCT06201520 | Chang Gung Memorial Hospital | N/A |
| Completed | Urdu Version of Maastricht Upper Extremity Questionnaire Reliability Validity Study. NCT06191003 | Riphah International University | — |
| Completed | Reliability and Validity of the Turkish Version of the 6-item Carpal Tunnel Syndrome Symptoms Scale NCT05927896 | Bursa City Hospital | — |
| Completed | Effects of High Intensity Laser on Mechanical and Physiological Findings in Pregnant Women With Carpal Tunnel NCT04969393 | October 6 University | N/A |
| Recruiting | Noninvasive Brain Stimulation for Treating Carpal Tunnel Syndrome NCT04206215 | Spaulding Rehabilitation Hospital | N/A |
| Enrolling By Invitation | Assessment of Carpal Tunnel Syndrome by Shearwave Elastography NCT04804293 | Mayo Clinic | N/A |
| Unknown | Acupuncture Versus Laser Acupuncture for Carpal Tunnel Syndrome NCT04828239 | Kuang Tien General Hospital | N/A |
| Completed | Comparative Effect of Scaphoid, Hamate Mobilization and Neural Mobilization in Patients With Carpal Tunnel Syn NCT05261880 | Riphah International University | N/A |
| Unknown | Dextrose, Corticosteroids and Surgical Release in Carpal Tunnel Syndrome NCT04014244 | University Medical Centre Ljubljana | N/A |
| Completed | Testing of a Tool to Elicit Patient Preferences for CTS NCT03532373 | Stanford University | N/A |
| Completed | Does the Diacutaneous Fibrolysis Change Ultrasonographic Measurements in Patients With Carpal Tunnel Syndrome? NCT04762238 | Universidad de Zaragoza | N/A |
| Completed | Effectiveness of a Tele-Rehabilitation Evidence-based Tablet App for Rehabilitation in Traumatic Bone and Soft NCT04669704 | University of Seville | N/A |
| Completed | The Relationship of Psychological Factors and Sleep Quality With the Severity of Carpal Tunnel Syndrome NCT05047367 | Cumhuriyet University | — |
| Completed | Corticosteroid And Ozone Injection In Patıents With Carpal Tunnel Syndrome NCT06237634 | Kayseri City Hospital | N/A |
| Recruiting | Corticosteroid Injection Effectiveness in Carpel Tunnel Patients With Negative or Mild EMG Studies NCT04737239 | Henry Ford Health System | — |
| Completed | Pain in Carpal Tunnel Release Wide-awake Local Anesthesia With no Tourniquet vs Local Anesthesia With Tourniqu NCT05747846 | Hospital Italiano de Buenos Aires | N/A |
| Unknown | A Comparison of Ultrasound-guided Steroid Injection With Wrist Splint in Carpal Tunnel Syndrome NCT04515966 | Mercy Health Ohio | Phase 4 |
| Unknown | Corticosteroid and Repeated Dextrose Hydro-dissection for Carpal Tunnel Syndrome Patients NCT04579783 | National Taiwan University Hospital | N/A |
| Unknown | Electrophysiological Changes Based on the Palmaris Longus NCT04619849 | Istanbul Medipol University Hospital | N/A |
| Terminated | Transthyretin Cardiac Amyloidosis in Patients With Idiopathic Carpal Tunnel Syndrome Referred for Release Surg NCT04611204 | University Hospital, Toulouse | — |
| Completed | Ibuprofen and Neural Mobilization Treatment in Carpal Tunnel Syndrome. NCT04328805 | Universidad Europea de Madrid | Phase 4 |
| Unknown | Avazzia HVPC Bio-Electrical Stimulation Technology (BEST™) Microcurrent CTS RCT NCT04271319 | Avazzia, Inc | N/A |
| Completed | Assessment of Subsynovial Connective Tissue Thickness in Carpal Tunnel Syndrome NCT04491058 | KU Leuven | — |
| Completed | Ultrasound Guided - Incisionless Threaded Carpal Tunnel Release NCT04101955 | Mayo Clinic | N/A |
| Completed | Effect of High-quality Pre-operative Videos on Patient Anxiety Levels Prior to Ambulatory Hand Surgery NCT04424810 | Northwell Health | N/A |
| Unknown | Evaluation of Ecography as a Diagnostic Tool in the Carpal Tunnel Syndrome Compared to the Studies of Electroc NCT05556278 | Hospital Universitario Virgen Macarena | — |
| Completed | Efficacy of Electroacupuncture in Carpal Tunnel Syndrome NCT04603274 | Aretaieion University Hospital | N/A |
| Completed | Comparison of the Efficacy of High Intensity Laser Therapy and Low Level Laser Therapy in the Carpal Tunnel Sy NCT06219876 | Ankara City Hospital Bilkent | N/A |
| Unknown | Systemic Transthyretin Amyloidosis: Carpal Tunnel Syndrome in a Portuguese Population NCT05409833 | Universidade do Porto | — |
| Completed | Physical Therapy in the Treatment of Carpal Tunnel Syndrome NCT04329247 | Universidad Europea de Madrid | N/A |
| Unknown | Comparison of Ultrasound-guided Corticosteroid Injection Versus Corticosteroid Injection and Hydrodissection f NCT04346030 | Taipei Veterans General Hospital, Taiwan | N/A |
| Completed | Pain Reduction Produced by Different Treatments in Carpal Tunnel Syndrome NCT04119739 | Francisco Unda Solano | Phase 4 |
| Completed | Oral Gabapentin and Median Nerve Mobilization in the Treatment of Carpal Tunnel Syndrome NCT04285281 | Universidad Europea de Madrid | Phase 4 |
| Completed | Percutaneous Electrical Nerve Stimulation for Carpal Tunnel Syndrome NCT04246216 | Universidad Rey Juan Carlos | N/A |
| Suspended | The SToICAL Study - The Soft Tissue Injection of Corticosteroid And Local Anaesthetic Study NCT04253457 | University Hospital Plymouth NHS Trust | Phase 3 |
| Completed | Mnaual Therapy in Treatment of Carpal Tunnel Syndrome NCT05150912 | Cairo University | N/A |
| Completed | Lidocaine Patch 1.8% for Moderate to Severe Pain From Carpal Tunnel Syndrome NCT04245371 | John Papakonstantinou, MD | Phase 4 |
| Completed | Novel Decision Aid for Carpal Tunnel Patients NCT04693273 | Henry Ford Health System | — |
| Unknown | Ultrasound-guided PRP Versus Steroid Injections in Management of Carpal Tunnel Syndrome NCT04434105 | Tanta University | Phase 2 / Phase 3 |
| Completed | Does Adding Lidocaine to Corticosteroid Injections Reduce Pain Intensity in Hand Surgery NCT06188221 | University of Texas at Austin | N/A |
| Unknown | Carpal Tunnel Syndrome and Amyloidosis NCT04245098 | Corporacion Parc Tauli | N/A |
| Completed | Conditioning Electrical Stimulation to Improve Outcomes in Carpal Tunnel Syndrome NCT04191538 | University of Alberta | Phase 1 / Phase 2 |
| Completed | Efficacy of Ultrasound-guided Transverse Carpal Ligament Release for Carpal Tunnel Syndrome NCT06251674 | Peking University People's Hospital | N/A |
| Completed | Radial Extracorporeal Shock Wave Therapy in the Treatment of Carpal Tunnel Syndrome NCT04416867 | Erzurum Regional Training & Research Hospital | N/A |
| Completed | Post Operative Dressing After Clean Elective Hand Surgery NCT04268095 | Itay Ashkenazi | N/A |
| Withdrawn | Wound Closure Study in Carpal Tunnel and Trigger Finger Surgery NCT03781141 | Mayo Clinic | N/A |
| Unknown | Effects of Cerebral & Peripheral Electrical Stimulation on Pain and Function in CTS NCT04092088 | Suez Canal University | N/A |
| Completed | Comparing Superficial vs. Deep Local Anesthetic Infiltration to Improve Patient Experience During Carpal Tunne NCT04201652 | University of Saskatchewan | N/A |
| Unknown | Combined Effect of Insulin and Sodium Hyaluronate Injection Guided by Ultrasound in Carpal Tunnel Syndrome NCT04142411 | Assiut University | EARLY_Phase 1 |
| Unknown | Neuromuscular Ultrasound in Correlation to Neurophysiological Findings NCT04092140 | Assiut University | — |
| Completed | Clinical Validation of a Decompression Prototype Splint for Patients With Carpal Tunel Syndrome NCT04043780 | Universidad de Zaragoza | N/A |
| Completed | Comparison of Interventions in Patients With Carpal Tunnel Syndrome NCT04347746 | Universidade Norte do Paraná | N/A |
| Completed | Pain Reduction and Changes in Upper Limb Function Produced by Different Treatments in Carpal Tunnel Syndrome NCT04025203 | Francisco Unda Solano | Phase 4 |
| Completed | Different Sessions of Perineural Injection With Dextrose for Carpal Tunnel Syndrome NCT03802435 | Tri-Service General Hospital | N/A |
| Completed | Prevalence of Wild Type Transthyretin Cardiac Amyloidosis in Patients Operated for Idiopathic Carpal Tunnel Sy NCT03996382 | Aarhus University Hospital Skejby | N/A |
| Completed | Safety and Efficacy of Percutaneous Carpal Tunnel Release Versus Open Surgery NCT04117516 | Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana | N/A |
| Completed | Prospective Randomized Trial of Monocryl Versus Nylon Suture Closure in Carpal Tunnel Surgery NCT03950401 | University of California, Davis | N/A |
| Unknown | Effectiveness of fESWT in the Treatment of CTS NCT04302909 | Medical University of Vienna | N/A |
| Withdrawn | Vitamin B12 for Carpal Tunnel Syndrome NCT03802422 | Tri-Service General Hospital | N/A |
| Completed | Question Prompt List for Common Hand Conditions NCT03868449 | Stanford University | N/A |
| Completed | Efficacy of Dry Needling With the Fascial Winding Technique in the Carpal Tunnel Syndrome NCT03907956 | Universitat Internacional de Catalunya | N/A |
| Completed | Carpal Tunnel Syndrome in Patients With Psoriatic Arthritis NCT05086029 | Selcuk University | — |
| Withdrawn | Validation of PSFS in Carpal Tunnel Syndrome NCT03909373 | Stanford University | — |
| Completed | Carpal Tunnel Syndrome in Patients With Psoriatic Arthritis; Ultrasonography and Magnetic Resonance Imaging Fi NCT05086042 | Selcuk University | — |
| Recruiting | Exparel and Education to Avoid Opioids After Carpal Tunnel Release NCT03867539 | Kettering Health Network | Phase 4 |
| Completed | Validation of the Polish Version of the Boston Carpal Tunnel Syndrome Questionnaire NCT03782558 | Jakub Antczak | — |
| Completed | Comparison of the Efficacy of Corticosteroid Injection and ESWT in Patients With CTS NCT03792945 | Ahi Evran University Education and Research Hospital | Phase 4 |
| Unknown | Safety and Efficacy of a Device for the Relief of Pain Due to Carpal Tunnel Syndrome NCT03810326 | Yuinvent Innovations Ltd. | N/A |
| Withdrawn | Alternatives to Hand Therapy for Hand Surgery Patients NCT03779958 | Stanford University | — |
| Completed | PAVmed CarpX Device Clinical Study NCT03747510 | PAVmed Inc. | N/A |
| Withdrawn | Comparison of Focused and Radial Extracorporeal Shock Wave for Carpal Tunnel Syndrome NCT03671473 | Tri-Service General Hospital | N/A |
| Unknown | Efficacy of Laser Acupuncture for Carpal Tunnel Syndrome NCT03580265 | Tri-Service General Hospital | N/A |
| Unknown | Neuromedulatory Effect of Transcranial Direct Current Electrical Stimulation in Carpal Tunnel Syndrome NCT03795961 | Suez Canal University | N/A |
| Completed | Short-Term Effectiveness of Ultrasound-Guided Corticosteroid Hydrodissection NCT04848324 | Gaziler Physical Medicine and Rehabilitation Education and Research Hospital | N/A |
| Completed | Local Injection of Ozone Versus Methylprednisolone Acetate in Carpal Tunnel Syndrome of Scleroderma Patients NCT03742466 | Assiut University | N/A |
| Completed | Tourniquet vs. No Tourniquet for Carpal Tunnel and Trigger Finger Release NCT04354415 | Maisonneuve-Rosemont Hospital | N/A |
| Unknown | IMpact of Perineural Hydrodissection Over Alternative Therapies in Patients With Carpal Tunnel Syndrome NCT03616353 | Leslie Witton | EARLY_Phase 1 |
| Completed | Non-invasive CTS Device Clinical Trial NCT03498287 | Pressure Profile Systems, Inc. | N/A |
| Completed | The Effect Of An Anesthetic Procedure On Post Operative Pain Management In Carpal Tunnel Release NCT03729375 | University of South Florida | Phase 1 |
| Completed | Decision Making in Hypothetical Carpal Tunnel Syndrome NCT03730376 | Stanford University | N/A |
| Completed | Cost Information on Carpal Tunnel Syndrome Treatment Decisions NCT03880812 | University of Texas at Austin | N/A |
| Unknown | Radiofrequency, Perineural Injection, Idiopathic Carpal Tunnel Syndrome NCT05053477 | Alexandria University | Phase 1 |
| Completed | The Volume Effect of Nerve Hydrodissection for Carpal Tunnel Syndrome NCT03381521 | Tri-Service General Hospital | N/A |
| Unknown | Platelet Rich Plasma in Carpal Tunnel Syndrome NCT04000932 | Baskent University | Phase 3 |
| Completed | Body Schema Alterations in Musculoskeletal Disorders : Effect of Laterality NCT03567109 | University Hospital, Angers | — |
| Completed | The Volume Effect of Hydrodissection for Carpal Tunnel Syndrome NCT03598322 | National Taiwan University Hospital | N/A |
| Completed | Effects of Platelet-rich Plasma in the Surgery of Carpal Tunnel Syndrome: A Randomized Controlled Trial NCT03548259 | Cardenal Herrera University | N/A |
| Completed | Efficacy of Focused Shockwave Therapy in Patients With CTS NCT05253729 | Mahidol University | N/A |
| Completed | Preoperative Antibiotics for Carpal Tunnel Release Surgery NCT03432858 | WellSpan Health | Phase 4 |
| Completed | Efficacy of Local Direct Median Nerve Block NCT04453462 | Thammasat University | N/A |
| Completed | Extracorporeal Shock Wave Versus Local Corticosteroid Injection for Carpal Tunnel Syndrome NCT04767724 | Chinese Medical Association | Phase 4 |
| Completed | Hydrodissection as a Treatment for Carpal Tunnel Syndrome NCT03427983 | Mayo Clinic | N/A |
| Completed | Onset and Duration of Forearm Nerve Blockade NCT03649763 | New York School of Regional Anesthesia | Phase 4 |
| Completed | Amniotic Membrane in Carpal Tunnel Syndrome NCT04075357 | Instituto de Oftalmología Fundación Conde de Valenciana | N/A |
| Completed | Nylon Versus Chromic Gut Sutures for Minor Hand Surgery NCT03407820 | University of Texas at Austin | N/A |
| Completed | Intraneural Facilitation as a Treatment for Carpal Tunnel Syndrome NCT03205683 | Loma Linda University | N/A |
| Completed | Ultrasound-guided Peripheral Nerve Block Versus Forearm Bier's Block in Patients Undergoing Carpal Tunnel Rele NCT03411551 | Jessa Hospital | N/A |
| Unknown | Concomitant Basal Joint Arthroplasty and Carpal Tunnel Release NCT04391751 | Hospital Universitari Vall d'Hebron Research Institute | N/A |
| Completed | Research Protocol for Karuna Labs Inc.: Safety and Efficacy of Virtual Reality Graded Motor Imagery for Chroni NCT04060875 | Karuna Labs Inc. | — |
| Completed | Platelet Rich Plasma for Carpal Tunnel Syndrome NCT03184688 | Tri-Service General Hospital | N/A |
| Completed | Hyaluronic Acid Hydro-dissection Use in Idiopathic Carpal Tunnel Syndrome Guided by Ultrasonic Study NCT03180125 | Assiut University | Phase 1 |
| Completed | Platelet-Rich Plasma in the Treatment of Patients With Idiopathic Carpal Tunnel Syndrome NCT03863873 | Mansoura University | N/A |
| Completed | Effectiveness of Neurodynamic Techniques for the Treatment of Carpal Tunnel Syndrome NCT03243227 | University of Jordan | N/A |
| Completed | Study of Single Platelet-Rich Plasma Local Injection Vs. Single Corticosteroid Local Injection in Carpal Tunne NCT06209957 | Menoufia University | Phase 4 |
| Completed | Preoperative Pain Neuroscience Education in Patients With Carpal Tunnel Syndrome NCT03576196 | Hospital Clínico La Florida | N/A |
| Completed | Surgical Treatment of Carpal Tunnel Syndrome: Local Anesthesia With Epinephrine x Intravenous Regional Anesthe NCT02986347 | Hospital Alvorada | N/A |
| Completed | Ibuprofen Plus Acetaminophen Versus Oxycodone Alone After Hand Surgery NCT03111186 | University of Southern California | Phase 2 |
| Completed | Efficacy of Hyalase Hydro-dissection in Treatment of Carpal Tunnel: Randomized Double Blind Controlled Clinica NCT03675295 | Assiut University | N/A |
| Completed | The Effect of Hyaluronic Acid for Carpal Tunnel Syndrome NCT03031054 | Tri-Service General Hospital | N/A |
| Completed | Corticosteroid Injection in Carpal Tunnel Syndrome NCT03072290 | Taipei Veterans General Hospital, Taiwan | N/A |
| Completed | Median Nerve Injury in US-guided Carpal Tunnel Injections NCT03391336 | yi-chih HSU | — |
| Completed | Comparison of Difference Hydrodissection for CTS NCT03031041 | Tri-Service General Hospital | N/A |
| Completed | The Effect of Hydrodissection for Carpal Tunnel Syndrome NCT02991001 | Tri-Service General Hospital | N/A |
| Suspended | Lipografting Versus Steroid Injections for Treatment of Carpal Tunnel Syndrome NCT03722303 | Columbia University | EARLY_Phase 1 |
| Completed | The Effect of Perineural Injection Therapy Versus Steroid in Patients With Carpal Tunnel Syndrome NCT02990962 | Tri-Service General Hospital | N/A |
| Completed | Platelet Rich Plasma and Hydrodissection for Carpal Tunnel Syndrome NCT02986828 | Tri-Service General Hospital | N/A |