Trials / Unknown
UnknownNCT04434105
Ultrasound-guided PRP Versus Steroid Injections in Management of Carpal Tunnel Syndrome
Ultrasound-guided PRP Versus Steroid Injections in Management of Carpal Tunnel Syndrome; a Comparative Study
- Status
- Unknown
- Phase
- Phase 2 / Phase 3
- Study type
- Interventional
- Enrollment
- 90 (actual)
- Sponsor
- Tanta University · Academic / Other
- Sex
- All
- Age
- 20 Years – 60 Years
- Healthy volunteers
- Not accepted
Summary
Patients will be randomly divided into 3 equal groups: Group I received ultrasound guided injection of 2 mL PRP into the affected carpal tunnel. Group II received ultrasound guided injection of 2 mL steroids (40 mg triamcinolone acetonide). Group III received ultrasound guided injection of 2 mL saline as placebo control.
Detailed description
Patients will be randomly divided into 3 equal groups: Group I received ultrasound guided injection of 2 mL PRP into the affected carpal tunnel. Group II received ultrasound guided injection of 2 mL steroids (40 mg triamcinolone acetonide). Group III received ultrasound guided injection of 2 mL saline as placebo control. Each group will be injected twice with 2 weeks intervals. All procedures were done after informed consent. Evaluation of the patients at baseline, 3 and 6 months after last injection was done clinically by measuring visual analogue scale (VAS), electrophysiologically (by measuring motor and sensory nerve conduction studies of median nerve using a standardized technique) and ultrasonographic study by measuring cross sectional area (CSA) of median nerve at the level of pisiform.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | platlet rich plasma (PRP) | Platelet-rich plasma (PRP) promotes angiogenesis, neurogenesis, and nerve regeneration, also it could reduce swelling and inflammation of the flexor tenosynovitis. |
| DRUG | Triamcinolone Acetonide | 40 mg triamcinolone acetonide |
| DRUG | Saline | Saline |
Timeline
- Start date
- 2020-02-01
- Primary completion
- 2020-11-01
- Completion
- 2020-12-01
- First posted
- 2020-06-16
- Last updated
- 2020-06-16
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT04434105. Inclusion in this directory is not an endorsement.