NCT06237634

Corticosteroid And Ozone Injection In Patıents With Carpal Tunnel Syndrome

Comparison Of The Effectiveness Of Ultrasound Acrossed Corticosteroid And Ozone Injection In Patıents With Carpal Tunnel Syndrome

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 90 (actual)
• Sponsor: Kayseri City Hospital · Other Government
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

There are a limited number of studies on the use of ozone in CTS.The aim of this clinical study is to compare the effectiveness of corticosteroid injections and ozone injections added to splint and exercise therapy in mild-moderate CTS patients.. 106 patients included in the study were randomized and divided into three groups. During the follow-up, a total of 90 patients, 30 patients in each group, completed the study.

Detailed description

106 patients included in the study were randomized and divided into three groups. During the follow-up, a total of 90 patients, 30 patients in each group, completed the study. Neutral hand-wrist rest splint and tendon-nerve gliding exercises were given to 30 patients included in the control group. In addition to the treatment given to the first group, 40 mg (1 ml) triamcinolone acetonide was injected under USG guidance to 30 patients included in the corticosteroid group. In addition to splint and exercise therapy, 3 cc ozone (O2-O3), 10 micrograms were injected under USG guidance to 30 patients in the ozone group. Patients in all three groups were evaluated at the beginning of treatment, 6 weeks and 3 months after treatment. Evaluation methods include provocative tests (Tinnel, Phallen, Flick tests), visual analogue scale (VAS) numbness day/night and VAS pain scores, sensory tests (two-point discrimination and Semmes Weinstein monofilament test (SWMT)), hand and finger grip strengths. measurement, Boston carpal tunnel syndrome questionnaire (BCTA), median nerve cross-sectional area (MSCA) measurement with USG and electrophysiological parameters were used.

Conditions

• Carpal Tunnel Syndrome

Interventions

Type	Name	Description
OTHER	splint and exercise and advices	A hand-wrist support splint and tendon shifting exercises were applied to the upper extremity of the affected side.
OTHER	Triamsinolon Asetonid ozone	40 mg (1 ml) of triamcinolone acetonide was injected to the median nerve's around at wrist level under ultrasound guidance.
OTHER	ozone	In addition to the treatment and recommendations given to the first group, the affected side was injected with ultrasound-guided 3 cc ozone (O2-O3) into the wrist with a concentration of 10 micrograms/ml.

Timeline

• Start date: 2021-01-01
• Primary completion: 2021-04-10
• Completion: 2021-09-15
• First posted: 2024-02-01
• Last updated: 2024-02-01

Locations

2 sites across 1 country: Turkey (Türkiye)