Trials / Unknown
UnknownNCT05409833
Systemic Transthyretin Amyloidosis: Carpal Tunnel Syndrome in a Portuguese Population
Systemic Transthyretin Amyloidosis: Carpal Tunnel Syndrome in a Portuguese Population (CarPoS Study)
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 100 (estimated)
- Sponsor
- Universidade do Porto · Academic / Other
- Sex
- All
- Age
- 60 Years
- Healthy volunteers
- Not accepted
Summary
Systemic transthyretin amyloidosis is an aging-related disorder. It is usually associated with cardiac disease but also extends to other organs. Recent studies found that idiopathic carpal tunnel syndrome patients may have amyloid deposition in tenosynovial tissue. The main aims of this project are the characterization of the association between idiopathic carpal tunnel syndrome and transthyretin amyloidosis and its evaluation as a predictive factor of cardiac amyloidosis
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Synovial biopsy and Cardiac scintigraphy with [99mTc]Tc-DPD | Congo red and Immunohistochemical analysis and/or Mass spectrometry analysis |
Timeline
- Start date
- 2020-06-01
- Primary completion
- 2024-06-01
- Completion
- 2025-06-01
- First posted
- 2022-06-08
- Last updated
- 2023-10-19
Locations
2 sites across 1 country: Portugal
Source: ClinicalTrials.gov record NCT05409833. Inclusion in this directory is not an endorsement.