NCT06781489

Pain Reduction Caused by the Combined Treatment of Physiotherapy, Oral Gabapentin and Oral Ibuprofen Arginine.

Pain Reduction Caused by the Combined Treatment of Neural Mobilization, Oral Gabapentin and Oral Ibuprofen Arginine in the Treatment of Carpal Tunnel Syndrome

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 129 (actual)
• Sponsor: Universidad Europea de Madrid · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

In the present investigation the pain reduction effects of a physiotherapy technique combined with gabapentin and ibuprofen arginine will be compared to those produced by an ibuprofen arginine (only) treatment, in subjects who suffer the signs and symptoms of carpal tunnel syndrome.

Detailed description

The present randomized clinical trial will perform a comparison of (group 1) the pain reduction effects produced by the application of a non invasive and non pharmacological median nerve neural mobilization (physiotherapy treatment) combined with a pharmaceutical oral gabapentin treatment versus (group 2) median nerve neural mobilization (physiotherapy treatment) combined with a pharmaceutical oral ibuprofen arginine treatment, to those effects produced by (group 3) ibuprofen arginine (only) treatment. Additionally, effects over the functionality of the affected upper limb will be evaluated and compared. Subjects will be invited to participate and randomly allocated to 2 different groups.

Conditions

• Carpal Tunnel Syndrome

Interventions

Type	Name	Description
OTHER	Median nerve neural mobilization	Manual therapy maneuver performed in the upper limb
DRUG	Gabapentin 300mg	Oral gabapentin capsule
DRUG	Ibuprofen Arginine	Oral ibuprofen arginine tablets

Timeline

• Start date: 2025-02-19
• Primary completion: 2025-03-20
• Completion: 2025-03-29
• First posted: 2025-01-17
• Last updated: 2025-12-11

Locations

1 site across 1 country: Venezuela