NCT06778759

Ibuprofen Arginine and Neural Mobilization Versus Ibuprofen Arginine in the Treatment of Carpal Tunnel Syndrome

Pain Reduction Effect of a Combined Oral Ibuprofen Arginine and Neural Mobilization Treatment Versus an (Only) Oral Ibuprofen Arginine Treatment in Carpal Tunnel Syndrome

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 76 (actual)
• Sponsor: Universidad Europea de Madrid · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

In the present investigation the pain reduction effects of a physiotherapy technique combined with pharmaceutical ibuprofen arginine treatment will be compared to those produced by ibuprofen (only) treatment, in subjects who suffer the signs and symptoms of carpal tunnel syndrome.

Detailed description

The present randomized clinical trial will perform a comparison of the pain reduction effects produced by the application of a non invasive and non pharmacological median nerve neural mobilization (physiotherapy treatment) combined with a pharmaceutical oral ibuprofen arginine treatment, to those effects produced by a ibuprofen arginine (only) treatment. Additionally, effects over the functionality of the affected upper limb will be evaluated and compared. Subjects will be invited to participate and randomly allocated to 2 different groups.

Conditions

• Carpal Tunnel Syndrome

Interventions

Type	Name	Description
COMBINATION_PRODUCT	median nerve neural mobilization combined with oral ibuprofen arginine	Manual therapy maneuver performed in the upper limb combined with ibuprofen arginine oral tablets
DRUG	Ibuprofen Arginine	Ibuprofen arginine oral tablets

Timeline

• Start date: 2025-02-19
• Primary completion: 2025-03-12
• Completion: 2025-03-19
• First posted: 2025-01-16
• Last updated: 2025-12-11

Locations

1 site across 1 country: Venezuela