NCT05280223

Dexmedetomidine Versus Hyalase Treatment of Carpal Tunnel Syndrome

Dexmedetomidine Versus Hyalase Local Injection for Pain Alleviation in Patients With Carpal Tunnel Syndrome; A Randomized Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

Carpal tunnel syndrome (CTS) is a common peripheral entrapment neuropathy, this study aims to investigate if, and to what extent hydro-dissection hyalase and saline versus dexmedetomidine upon the median nerve could offer symptoms and clinical improvement

Detailed description

Carpal tunnel syndrome (CTS) is the most common compression syndrome the upper extremities. Its problem has a high prevalence ranged estimated prevalence of 3.8% in the general population, 3 and 7.8% in the working population. It occurs at any age, especially in individuals in their 40s to 60s, and the male: female ratio is reported to be 3:7. A lot of treatment modalities have been tried to improve the condition, starting from local anesthetic injection, steroid, and up to surgical decompression of the nerves.

Conditions

• Carpal Tunnel Syndrome
• Pain, Chronic

Interventions

Type	Name	Description
DRUG	Dexmedetomidine	injection of 1 microgram/kg dexmeditomidine + 10 cc saline injection nearby median nerve as hydrodissection
DRUG	Hyalase	injection of Hyalase + 10 cc saline injection nearby median nerve as hydro-dissection

Timeline

• Start date: 2022-04-01
• Primary completion: 2023-06-30
• Completion: 2023-08-25
• First posted: 2022-03-15
• Last updated: 2023-10-31

Locations

1 site across 1 country: Egypt