| Withdrawn | Efficacy and Safety of Canadá Association in the Treatment of Chronic Pain NCT05125978 | EMS | Phase 2 |
| Not Yet Recruiting | Person-Centred AI Support in Interdisciplinary Rehabilitation for Chronic Pain NCT07081737 | Bjorn Ang | N/A |
| Not Yet Recruiting | Ultrasound Guided Pecs Block and Ketamine Infusion for Preventing Chronic Pain in Patients Undergoing Breast C NCT07197684 | Aga Khan University | N/A |
| Recruiting | Interoceptive Awareness and Function in Adolescents With Chronic Pain NCT07325110 | Connecticut Children's Medical Center | — |
| Recruiting | Home-based Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for IBS Pain NCT06847360 | Yale University | N/A |
| Not Yet Recruiting | Butyrate and Taurine for Chronic Postsurgical Pain in Adult Cardiac Surgical Patients NCT07144033 | Chinese University of Hong Kong | N/A |
| Recruiting | Pain Reprocessing Therapy in Post-Operative Knee Pain NCT06800209 | University of Colorado, Denver | Phase 2 |
| Not Yet Recruiting | Developing a Nonpharmacological Pain Intervention for Community-dwelling Older Adults With Dementia NCT06264362 | Drexel University | N/A |
| Recruiting | The PROACTIVE Study for Black Elders NCT06512727 | University of Florida | N/A |
| Not Yet Recruiting | Methadone Dose Monitoring With a Remote Medication Monitor NCT06837571 | Cari Health Inc. | — |
| Recruiting | Prescription Opioids, Brain Structure, and Cognition in Older Adults With Chronic Pain NCT06837857 | Mayo Clinic | Phase 2 |
| Not Yet Recruiting | Prospective Validation Study of an E-health Tool for Patient Selection for SCS NCT06853795 | Erasmus Medical Center | — |
| Active Not Recruiting | Cognitive Behavioral Therapy for Chronic Pain in Adults With Cerebral Palsy NCT06269926 | Hugo W. Moser Research Institute at Kennedy Krieger, Inc. | N/A |
| Completed | Physical Activity and Percussive Massage Therapy for Reducing Pain in Older Women NCT07056335 | University of Michigan | N/A |
| Completed | Effect of Mirror Therapy on the Arteriovenous Fistula Cannulation-related Pain and Anxiety NCT06683495 | Istanbul University | N/A |
| Withdrawn | Apply the PD Model of Peripheral Oxytocin Action to a Multimodal Stimulus NCT04433741 | Wake Forest University Health Sciences | Phase 2 |
| Recruiting | Sleep Well Despite Persistent Pain Symptoms NCT06351839 | University of Tromso | N/A |
| Active Not Recruiting | Management Modalities of Chronic Pelvic Pain NCT06719635 | Zagazig University | N/A |
| Not Yet Recruiting | Investigation of Grip Strength, Pain and Anxiety Levels in Dentists NCT06721117 | Hacettepe University | — |
| Recruiting | Adolescent Outcomes of Post-operative Opioid EXposure NCT06350409 | Sharon Levy | — |
| Completed | Transcultural Validation of the French Version of the " Patients' Endorsement of a Biopsychosocial Model of Ch NCT06698406 | Benno Rehberg-Klug | — |
| Recruiting | Ziconotide for Non-cancer Pain by Intrathecal Administration NCT06541184 | ESTEVE Pharmaceuticals SAS | — |
| Not Yet Recruiting | Feasibility of Using an App for Managing Phantom Limb Pain Associated with Combat Injury in Ukraine (PAMELA) NCT06604507 | Winfried Meißner | — |
| Recruiting | Affecting Factors for Chronic Pain After Mastectomy NCT06592053 | Ankara Etlik City Hospital | — |
| Completed | The Impact Of Fascia Thickness on Chronic Low Back Pain NCT06572007 | Okan University | — |
| Recruiting | Affecting Factors for Chronic Pain After Sternotomy NCT06534372 | Ankara Etlik City Hospital | — |
| Completed | Comparison of the Efficacy of Posterior Tibial Nerve Neuromodulation and Extracorporeal Shock Wave Therapy for NCT06558552 | Halil Ibrahim Altun | N/A |
| Recruiting | Assessment of Methadone Dose Taken NCT05981573 | Cari Health Inc. | — |
| Completed | Use of Ketamine in Severe Pain Syndromes NCT06537375 | Erasme University Hospital | — |
| Recruiting | Nutrition Care in Patients Living With Chronic Pain NCT06277232 | Linkoeping University | N/A |
| Recruiting | Embo Registry; National Registry for Artery Embolization NCT06477965 | Vascular Solutions of North Carolina | — |
| Completed | Effectiveness of Endovascular Plug Embolization in Pelvic Congestion Syndrome NCT06553014 | Halil Ibrahim Altun | — |
| Completed | Efficacy of Pain Neuroscience Education and Pre-anesthetic Assessment in Reducing Levels of Anxiety, Stress an NCT05435508 | Instituto Neurociencia Del Dolor | N/A |
| Not Yet Recruiting | Evaluation of Work Productivity and Activities of the Fibromyalgia Patients' Relatives NCT06357793 | Başakşehir Çam & Sakura City Hospital | — |
| Completed | The Effects of Neuroscience Based Proprioceptive Exercise Training NCT06554483 | Pamukkale University | N/A |
| Unknown | Effectiveness of the Sana Device on Fibromyalgia Symptoms NCT05394610 | Sana Health | N/A |
| Completed | Breathwork for Chronic Musculoskeletal Pain NCT06455839 | Florida State University | N/A |
| Enrolling By Invitation | Efficacy of a Chronic Pain Treatment Prior to Gender-affirming Surgery NCT06443164 | Oregon Health and Science University | N/A |
| Completed | Understanding and Managing Pain for Thalidomide Survivors NCT06398132 | University of Nottingham | — |
| Unknown | Focal Microvibration and Chronic Lumbosacral Radicular Pain NCT06301061 | Federico II University | N/A |
| Completed | Impact of Sedation on Patient Satisfaction, Radiation Exposure, and Complications in Lumbar Transforaminal Epi NCT06539390 | Kanuni Sultan Suleyman Training and Research Hospital | — |
| Recruiting | Stellate Ganglion Block for Prevention of Post Mastectomy Depression NCT06263907 | Mansoura University | N/A |
| Recruiting | Lumbar ESPB in Hip Replacement Surgery NCT06282666 | Medical University of Lublin | N/A |
| Completed | The Effects of Music on Neck Pain NCT06285383 | KTO Karatay University | N/A |
| Recruiting | MIVetsCan: Cannabidiol (CBD)-Care Trial NCT06213233 | Kevin Boehnke | Phase 2 |
| Completed | The Effect of Listening to Music on Chronic Low Back Pain NCT06263803 | KTO Karatay University | N/A |
| Completed | The PainSMART Research Program: Evaluating a Pain Education Strategy for Patients Seeking Primary Care Physiot NCT06187428 | Kajsa Johansson | N/A |
| Completed | Online Psychology Program for Chronic Pain After Surgery NCT06455345 | University Health Network, Toronto | N/A |
| Recruiting | Evaluation of Cognitive Behavioral Therapy for Long-term Pain in Rheumatic Disease, Including Validation of AE NCT06413914 | Diakonhjemmet Hospital | N/A |
| Active Not Recruiting | Intravenous Methadone in Perioperative Acute and Chronic Management in Chinese Adult Cardiac Surgical Patients NCT05913284 | Chinese University of Hong Kong | Phase 3 |
| Recruiting | VR and Cooled Genicular Nerve Radio Frequency Ablation for Chronic Knee Pain NCT06336447 | Northwestern University | N/A |
| Recruiting | Evaluating the Efficacy of the Pain Identification and Communication Toolkit NCT06168604 | Weill Medical College of Cornell University | N/A |
| Recruiting | Translation and Validation of the COMM and ASI-SR NCT06084520 | Uppsala University | — |
| Completed | Turkish Version of the Worry About Pain Questionnaire NCT06052228 | Istinye University | — |
| Unknown | Great Occipital Nerve Block Using Different Approach NCT06149299 | Keimyung University Dongsan Medical Center | N/A |
| Completed | Prevalence of Pain in Hospitalized Cirrhotic Patients NCT06062108 | Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer | — |
| Unknown | Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Back Pain NCT06071962 | Apurano Pharmaceuticals GmbH | Phase 3 |
| Unknown | Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Ge NCT06072001 | Apurano Pharmaceuticals GmbH | Phase 3 |
| Unknown | Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral NCT06071936 | Apurano Pharmaceuticals GmbH | Phase 3 |
| Unknown | Efficacy and Tolerability of AP707 in Patients With Chronic Back Pain NCT06072560 | Apurano Pharmaceuticals GmbH | Phase 3 |
| Unknown | Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative NCT06071988 | Apurano Pharmaceuticals GmbH | Phase 3 |
| Unknown | Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis NCT06071949 | Apurano Pharmaceuticals GmbH | Phase 3 |
| Completed | Usability Evaluation of a Mindfulness-based Serious Game NCT06522425 | Samsung Medical Center | N/A |
| Unknown | Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Diabetic Polyneuropathy NCT06072573 | Apurano Pharmaceuticals GmbH | Phase 3 |
| Unknown | Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Diabetic Polyneuropathy NCT06071975 | Apurano Pharmaceuticals GmbH | Phase 3 |
| Completed | Empowered Relief Delivered by Nurses NCT05934435 | Washington State University | N/A |
| Recruiting | UltrasouNd-guided Percutaneous Intercostal Nerve Cryoneurolysis for Analgesia Following Traumatic Rib Fracture NCT05865327 | Sunnybrook Health Sciences Centre | N/A |
| Recruiting | Relieving Chronic Pain in Older Adults With Transcranial Direct Current Stimulation NCT05617027 | Université de Sherbrooke | N/A |
| Enrolling By Invitation | Pain Pressure Threshold in Elbow Pain NCT06068907 | Istanbul University - Cerrahpasa | — |
| Completed | Comparison of Ultrasound-Guided Perimeniscal Steroid and 5% Dextrose Injections in Knee Osteoarthritis NCT06308887 | Kastamonu University | Phase 4 |
| Recruiting | Precision Medicine for Nociception, Sngception and Proprioception. NCT06161038 | National Taiwan University Hospital | N/A |
| Completed | APM in the Evoke SCS System to Program Patients With Chronic Pain of the Trunk and/or Limbs NCT06057480 | Saluda Medical Pty Ltd | N/A |
| Recruiting | Pain AND Opioids After Surgery NCT05877157 | University of Aberdeen | — |
| Enrolling By Invitation | Hypnotic Cognitive Therapy Reduce Acute & Chronic SCI Pain in Inpatient Rehabilitation NCT05047120 | University of Washington | N/A |
| Unknown | Safety and Efficacy of Low-intensity Laser Therapy in the Treatment of Chronic Musculoskeletal Pain NCT06009900 | Tongji Hospital | N/A |
| Completed | Virtual Reality - A New Vision on Pain NCT06045741 | Sykehuset i Vestfold HF | — |
| Recruiting | Screening Trial for Pain Relief in Schwannomatosis (STARFISH) NCT05684692 | Massachusetts General Hospital | Phase 2 |
| Recruiting | 7 Tesla MRI Brain Imaging to Decipher Filgotinib's Mode of Analgesic Action in Rheumatoid Arthritis NCT05697159 | NHS Greater Glasgow and Clyde | — |
| Recruiting | Perfusion MRI-targeted Joint Embolization for Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee NCT05700682 | Palo Alto Veterans Institute for Research | — |
| Terminated | The Effects of Daily Anti-inflammatory Supplementation on Foundation Pain Index Scores in Chronic Opiate Patie NCT05896878 | Hudson Medical | N/A |
| Recruiting | Offset Mechanisms in Evaluation of Lumbar Medial Branch Blocks NCT05961800 | University of Pittsburgh | N/A |
| Completed | Pain at Work Toolkit in Employees With Chronic Pain NCT05838677 | University of Nottingham | N/A |
| Unknown | Combined Physical and Psychological Intervention in Carpal Tunnel Syndrome Patients With Nociplastic Pain NCT05915611 | Ahram Canadian University | N/A |
| Completed | Feasibility of Remote Tai Chi NCT05693805 | Boston University | N/A |
| Completed | Comparison of Unilateral and Bilateral Transforaminal Epidural Steroid Injection NCT06240793 | Ankara University | N/A |
| Completed | Pulsed Radiofrequency to the Suprascapular Nerve NCT06527014 | Ankara City Hospital Bilkent | N/A |
| Recruiting | Sleep, Pain and Stress in Adolescents With Persistent Pain NCT05677412 | Helsinki University Central Hospital | N/A |
| Active Not Recruiting | Resilience Coaching for Adolescents With Chronic Musculoskeletal Pain NCT05834725 | Children's Hospital of Philadelphia | N/A |
| Unknown | Pain Management In Knee Osteoarthritis NCT05844319 | Istanbul University | N/A |
| Completed | Respiratory Biofeedback Sensor for Yoga Practice for Youth With Chronic Pain. NCT05791435 | Nemours Children's Clinic | N/A |
| Unknown | Dexmedetomidine and Morphine as Adjuvants to US Guided Erector Spinae Plane Blocks in Elective Thoracic Surger NCT05843344 | Dr Kassiani Theodoraki | N/A |
| Terminated | Study to Evaluate Neuromodulation Subject Experience With Contemporary Spinal Cord Stimulation (SCS) Modalitie NCT05775510 | MedtronicNeuro | — |
| Active Not Recruiting | Acceptability and Efficacy of Pain Reprocessing Therapy in Racially/ Ethnically Diverse Adults With Chronic Ba NCT05820204 | University of Colorado, Denver | N/A |
| Unknown | Evaluation of the Effect of a Food Supplement Based on Hydrolyzed Collagen on Joint Function. NCT05917925 | Francisco Javier Martínez Noguera | N/A |
| Active Not Recruiting | Pain Reduction Through Empowered Recovery (PRIME) Study NCT05619510 | Johns Hopkins University | N/A |
| Recruiting | Predictive and Impact of Pain After 6 Months of Radiotherapy, in Head and Neck Cancer NCT05505188 | University Hospital, Caen | N/A |
| Completed | Students' Understanding and Beliefs About Pain Before and After a One-day Pain Science Education Conference: a NCT05722587 | Teesside University | N/A |
| Unknown | Prediction of Clinical Outcome in Lumbar ESPB NCT05723367 | Keimyung University Dongsan Medical Center | — |
| Unknown | Clinical Efficacy of Axillary Block in Cervical Radiculopathy NCT05723354 | Keimyung University Dongsan Medical Center | N/A |
| Completed | Prediction of Clinical Outcome in Thoracic ESPB NCT05723380 | Keimyung University Dongsan Medical Center | — |
| Completed | Sympatholytic Effect of Thoracic ESP NCT05723393 | Keimyung University Dongsan Medical Center | N/A |
| Unknown | Prediction of Clinical Outcome in Axillary Block NCT05723419 | Keimyung University Dongsan Medical Center | — |
| Completed | Dry Cupping Therapy in Knee Osteoarthritis NCT04331158 | Universidade Federal do Rio Grande do Norte | N/A |
| Unknown | Telemedicine Improves Pain-related Disabilities in Following up Cancer Pain Outpatient NCT05628246 | Mahidol University | N/A |
| Recruiting | Web-based Pain Coping Skills Training for Breast Cancer Survivors With AI-Associated Arthralgia NCT05703178 | Northwestern University | Phase 3 |
| Completed | The Effect of Pain Education on Chiropractic Students' Understanding of Chronic Pain NCT05359900 | Teesside University | N/A |
| Recruiting | Comparative Effectiveness of Online 8-session CBT vs. 1-Session Empowered Relief for Chronic Pain - The PROGRE NCT05612750 | Stanford University | N/A |
| Completed | Multimodal Intervention in Patients With Non-specific Chronic Low Back Pain: the HEALTHY BACK Project NCT06114264 | IBS Granada | N/A |
| Recruiting | Opioid-free Anaesthesia in Breast Cancer Surgery NCT06404983 | University of Ioannina | N/A |
| Withdrawn | Study on the Use of Intraoperative Neurophysiological Monitoring in Spinal Cord Stimulator Trials NCT05540756 | University of Chicago | — |
| Unknown | Comparison of Alfredson and Silbernagel Protocol in Competitive Athletes With Achilles Tendinopathy NCT05659134 | Charles University, Czech Republic | N/A |
| Unknown | Continuous Sciatic Nerve Block vs Epidural Analgesia in Lower Limb Amputation for Postoperative Pain NCT05608733 | Universidad de Antioquia | Phase 3 |
| Recruiting | Light Exposure on Pain in Hypermobile Ehlers-Danlos Syndrome NCT05561270 | New York Institute of Technology | N/A |
| Completed | Ultrasound-Guided Vs Non-Guided Prolotherapy for Internal Derangement of Temporomandibular Joint. a Randomized NCT05627830 | Cairo University | N/A |
| Unknown | Progressive Relaxation Training Effect On Pain, Activity And Social Participation In Women With Tension-Type H NCT06050382 | Hacettepe University | N/A |
| Unknown | Opioid Sparing Anesthesia in Cervical Spine Surgery NCT05717361 | Evangelismos Hospital | N/A |
| Unknown | Tapentadol Versus Tramadol Analgesia Post Cardiac Surgery NCT04718116 | Aretaieion University Hospital | N/A |
| Unknown | Effectiveness of Pressure Biofeedback Therapy and Progressive Muscle Relaxation Technique in Improving Pain an NCT05616702 | Dow University of Health Sciences | N/A |
| Completed | App-delivered Cognitive-behavioral Therapy for Insomnia Among Patients With Musculoskeletal Complaints NCT05572697 | Norwegian University of Science and Technology | N/A |
| Unknown | Performance and Long-term Safety of FlowOx2.0™ in Patients With Multiple Sclerosis - Impact on Spasticity and NCT05562453 | Otivio AS | N/A |
| Withdrawn | VR Mindfulness Study NCT05592782 | University of California, Los Angeles | N/A |
| Recruiting | APP-based Precise Management System of Chronic Intractable Pain NCT05761392 | Beijing Tsinghua Chang Gung Hospital | N/A |
| Completed | Alpha Entrainment for Pain and Sleep (Extension) NCT05699837 | University of Manchester | N/A |
| Completed | Using Immersive Virtual Reality to Treat Complex Regional Pain Syndrome in Adults NCT05888142 | University of Washington | N/A |
| Completed | Pain Neuroscience Education and Therapeutic Exercise as a Treatment for Breast Cancer Survivors Living With Se NCT05452499 | Universidad Autónoma de Yucatán | N/A |
| Not Yet Recruiting | PROCO Neck: The Course and Neuroplasticity in Neck Pain-Associated Disorders and Whiplash-Associated Disorders NCT05468684 | University of applied sciences | — |
| Completed | PR-VR At-home Program During and After COVID-19 NCT04912817 | The Hospital for Sick Children | N/A |
| Unknown | Optimizing Psychological Treatment for Pain After Breast Cancer NCT05444101 | University of Aarhus | N/A |
| Completed | Evaluation of the Effect of the AI500™ SINGLE-DOSE GEL Medical Device in Patients With Reduced Knee Function NCT05886608 | Contrad Swiss SA | N/A |
| Completed | Comparison of Analgesic Efficacy of Intrathecal Levobupivacaine With and Without Oral Tizanidine in Lower Limb NCT07310628 | All India Institute of Medical Sciences | Phase 4 |
| Completed | Pain Severity in Fibromyalgia Syndrome NCT05481086 | Kutahya Health Sciences University | — |
| Completed | Pain Relief After High Thoracic Eretor Spinae Block NCT05487313 | Keimyung University Dongsan Medical Center | N/A |
| Completed | Comparison of Pain Relief After Upper and Lower Lumbar Erector Spinae Plane Block NCT05487339 | Keimyung University Dongsan Medical Center | N/A |
| Unknown | Comparison of Pain Relief Between High Thoracic Erector Spinae Plane Block and Cervical Epidural Injection NCT05487326 | Keimyung University Dongsan Medical Center | N/A |
| Unknown | Pain-related Long Covid in Covid-19 Survivors NCT05520931 | Aalborg University | — |
| Unknown | Opioid Sparing Anesthesia in Lumbar Spine Surgery NCT05594407 | Aretaieion University Hospital | N/A |
| Unknown | Serratus Anterior Plane Block to Prevent Chronic Postoperative Pain in Breast Cancer NCT05494281 | Moroccan Society of Surgery | N/A |
| Completed | The Adolescent Surgery Experience: A Mixed Methods Analysis NCT05482919 | Children's Hospital of Philadelphia | — |
| Completed | Effectiveness and Safety of tDCS for Pain NCT05612165 | Pusan National University Yangsan Hospital | N/A |
| Completed | Dexmedetomidine or Hyalase : Which of Them Can Augment Lumbar Epidural Steroid Injection in Failed Back Surger NCT05370963 | Minia University | EARLY_Phase 1 |
| Withdrawn | Real-Time Accurate Pathology Inspection and Decompression Study NCT05347108 | KM Clinical Research Group | — |
| Unknown | Management of Knee Pain by Cooled Radiofrequency in Classical Anatomical Targets and Revised Targets NCT05363241 | Universidade Federal de Alfenas | N/A |
| Completed | Intra-articular Pulsed Radiofrequency in Chronic Knee Pain NCT06017674 | Başakşehir Çam & Sakura City Hospital | N/A |
| Completed | Dexmedetomidine Versus Hyalase Treatment of Carpal Tunnel Syndrome NCT05280223 | Assiut University | N/A |
| Completed | Fluoroscopic vs Ultrasound Guided Sacroiliac (SI) Joint Injection NCT05235295 | Diskapi Teaching and Research Hospital | N/A |
| Active Not Recruiting | Diagnostic and Prognostic Biomarkers for High-impact Chronic Pain: Development and Validation NCT04994249 | Stanford University | — |
| Completed | An Evaluation of a Public Health Campaign in a High School Setting Targeting Pain Related Knowledge and Belief NCT05636345 | Teesside University | N/A |
| Unknown | Opioid-free Anesthesia in Thyroidectomies NCT05243940 | Aretaieion University Hospital | N/A |
| Completed | Clonidine is Better Than Zopiclone for Insomnia Treatment in Chronic Pain Patients NCT05277038 | Salem Anaesthesia Pain Clinic | — |
| Completed | The Loneliness Epidemic Tailoring Interventions to Reduce Loneliness and Pain NCT05387447 | University of Nebraska | N/A |
| Unknown | Ozone Therapy in Patients With Diabetic Neuropathy NCT05000463 | Assiut University | N/A |
| Completed | Examining the Effects of Float-REST for Recovery in Individuals With Chronic Lower Back Pain NCT05260918 | West Virginia University | N/A |
| Completed | Predictive Factors on the Results of Epidural Adhesiolysis in Patient With Chronic Spinal Pain NCT05235308 | Diskapi Teaching and Research Hospital | — |
| Completed | Assessment of the Efficacy of Digital CBT for Anxiety in Adults With Chronic Musculoskeletal Pain NCT04907656 | Boston University Charles River Campus | N/A |
| Recruiting | Evaluation of a Collaborative Intervention to Promote Employer Contact and RTW Among People With CMD or Chroni NCT05216861 | Uppsala University | N/A |
| Recruiting | Prospective Study of Sensation and Satisfaction in Cancer and Transgender Mastectomy Patients NCT06094257 | Weill Medical College of Cornell University | — |
| Completed | Effectiveness of Ultrasound Versus Fluoroscopy Guided S1 Injections and Radiofrequency NCT05247892 | Diskapi Teaching and Research Hospital | N/A |
| Recruiting | Diabetic Neuropathy in Spinal Cord Stimulator Patients NCT04687215 | University of Chicago | — |
| Completed | Integrated Supported Biopsychosocial Self-Management for Back Related Leg Pain NCT05022121 | University of Minnesota | N/A |
| Terminated | H-coil TMS to Reduce Pain: A Pilot Study Evaluating Relative Efficacy of the H1 vs H7 Coil NCT04203199 | Wake Forest University Health Sciences | N/A |
| Completed | Nurse-led Pain Education Clinical Trial in Chronic Pain Patients NCT05482152 | Universiteit Antwerpen | N/A |
| Unknown | Effect of Ultrasound Guided Thoracic Interfascial Plane Block Versus Erector Spinae Plane Block After Mastecto NCT05176938 | Tanta University | N/A |
| Unknown | Pulsed Radiofrequency Versus Pulse Dose Pulsed Radiofrequency of the Pudendal Nerve in Patients With Pudendal NCT05024682 | Assiut University | N/A |
| Recruiting | A Study to Reduce Persistent Post-mastectomy Pain Using Opioid-free Anesthesia NCT05146778 | Gangnam Severance Hospital | N/A |
| Completed | Pulsed Radiofrequency Treatment in Lumbar Facet-Related Pain NCT06157294 | Başakşehir Çam & Sakura City Hospital | N/A |
| Completed | More Individualized Care: Assessment and Recovery Through Engagement NCT05122676 | Kaiser Permanente | N/A |
| Completed | Psychobiological Mechanisms Underlying Chronic Pain NCT04674670 | susanne becker | N/A |
| Completed | The Effects of Cervical Mobilization on Cognitive Performance NCT05377645 | İSMAİL CEYLAN | N/A |
| Unknown | Opioid-free Anesthesia in Laparoscopic Cholecystectomies NCT05089526 | Aretaieion University Hospital | N/A |
| Recruiting | fMRI and IVCM Cornea Microscopy of CXL in Keratoconus NCT04439552 | Boston Children's Hospital | — |
| Recruiting | iCanCope With Post-Operative Pain (iCanCope PostOp) NCT05382962 | The Hospital for Sick Children | N/A |
| Recruiting | Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN) NCT04874038 | University Health Network, Toronto | Phase 3 |
| Completed | A Study of Cybis™ 10:25 THC:CBD Oil in Adults With Chronic Back/Neck Pain NCT04976738 | Cymra Life Sciences | Phase 1 / Phase 2 |
| Unknown | The Study of Hemp Oil CBD for Evaluation of Efficacy and Safety in Treatment of Pain, Anxiety and Insomnia Man NCT04729244 | Advanced Pain and Rehab Specialists | Phase 1 |
| Completed | Naldebain for Pain Management of Laparoscopic Cholecystectomy NCT04808544 | E-DA Hospital | Phase 2 / Phase 3 |
| Completed | Precision Medicine for Sng/Pain Control NCT05154695 | National Taiwan University Hospital | N/A |
| Unknown | Flippin Pain: A Public Health Campaign Evaluation NCT04903379 | Teesside University | N/A |
| Unknown | The Relationship of Disability With Depression, Anxiety and Sleep Quality in Patients With Coccygodynia NCT05047380 | Cumhuriyet University | — |
| Unknown | Development and Usability Testing of a Progressive WebApp for Women With Heart Disease NCT03800082 | University of Toronto | N/A |
| Unknown | Pharmacist-led Pharmacogenomic Clinical Service Within the Program of All-inclusive Care for the Elderly NCT04971902 | Tabula Rasa HealthCare | — |
| Unknown | Using Oral Valacyclovir to Treat Patients With Refractory IC/BPS NCT05094414 | Buddhist Tzu Chi General Hospital | Phase 1 |
| Completed | Comparing the Impact of Mindful Interoceptive Mapping and Mindful Breathing on Pain and Opioid Use NCT04523766 | University of Utah | N/A |
| Unknown | Naldebain for Pain Control After Bariatric Surgery NCT04651361 | E-DA Hospital | Phase 2 / Phase 3 |
| Unknown | Thumb and Wrist Proprioception Exercises. NCT04930718 | University of Malaga | N/A |
| Completed | Does Dry Needling Affect Treatment Outcomes of Interlaminar Epidural Steroid Injection in Cervical Disc Hernia NCT04914637 | Marmara University | N/A |
| Completed | Efficacy of Ultrasound Guided ESP Vs Video-assisted PVB Catheter Placement in Minimally Invasive Thoracic Surg NCT04729712 | Mater Misericordiae University Hospital | N/A |
| Unknown | COMPARISON OF SYSTEMIC INFLAMMATION-RELATED HEMATOLOGICAL PARAMETERS IN ACUTE AND CHRONIC LOW BACK PAIN NCT04897620 | Ufuk University | — |
| Completed | Evaluation of a Patient-Centred, Multidisciplinary Opioid Tapering Program for Individuals With Chronic Non-Ca NCT04902547 | University of Manitoba | N/A |
| Unknown | Developing a PROM for Recurrent Urinary Tract Infection NCT05086900 | University of Reading | — |
| Unknown | The Effect of Both Ultrasound and Fluoroscopy Guide Erector Spinae Plane Blocks NCT05044247 | National Taiwan University Hospital | N/A |
| Unknown | Morphine Versus Ketamine as Adjuvants in Paravertebral Blocks NCT04852484 | Aretaieion University Hospital | N/A |
| Unknown | Opioid-free Anesthesia With a Mixture of Dexmedetomidine-lidocaine-ketamine NCT04858711 | Aretaieion University Hospital | N/A |
| Completed | Position Sense, Force Control and Pain Intensity in Basal Thumb Osteoarthritis NCT04819139 | University of Malaga | N/A |
| Unknown | Pain Neuroscience Education and Graded Exposure to Movement in Breast Cancer Survivors NCT04965909 | University of Seville | N/A |
| Active Not Recruiting | PI-targeted PNE+MI Compared to BIOMEDICAL Education in BCS NCT04730154 | Universitair Ziekenhuis Brussel | N/A |
| Active Not Recruiting | Intermittent vs. Continuous Dorsal Root Ganglion Stimulation NCT04727216 | Spine and Pain Institute of New York | N/A |
| Unknown | S3 Root Pulsed Radiofrequency Added to Superior Hypogstric Plexus Block NCT04782206 | Assiut University | N/A |
| Completed | Resistance Training and Clinical Status in Patients With Post Discharge Symptoms After Covid-19 NCT04797871 | Universidad Pública de Navarra | N/A |
| Completed | Optimizing Psychological Treatment for Pain After Breast Cancer: A Pilot Study NCT04841928 | University of Aarhus | N/A |
| Completed | Evaluation of the Effect of Caudal Epidural Pulsed Radiofrequency Stimulation on Chronic Pain NCT05062993 | Diskapi Teaching and Research Hospital | N/A |
| Completed | Technology on the Occurrence of Muscoskeletal Disorders in Students NCT05253950 | University of Thessaly | — |
| Completed | Group intEgrative MINdfulness Over the Internet Using an Online Platform NCT04340739 | University of Massachusetts, Worcester | — |
| Completed | Effects of Transcranial Direct Current Stimulation on Pain Control in Chronic Painful Total Knee Arthroplasty NCT04579952 | Istituto Ortopedico Rizzoli | N/A |
| Completed | Cognitive Behavioural Therapy to Optimize Post-Operative Recovery Trial NCT04274530 | McMaster University | N/A |
| Completed | Use of Virtual Reality in Pain Management in Hospitalized Patients NCT05545033 | Changi General Hospital | N/A |
| Completed | Caregiver Burden and Correlation With Clinical Outcome in Spinal Cord Stimulation for Chronic Neuropathic Pain NCT04737746 | AZ Delta | — |
| Completed | Chronic Pain Diagnosis and Treatment in Torture Survivors NCT04629963 | Weill Medical College of Cornell University | N/A |
| Completed | Chronic Pain in COVID-19 Patients Discharged From Intensive Care Unit NCT04940208 | Mikhail Dziadzko, MD, PhD | — |
| Active Not Recruiting | Project 1 Aim 2, Adaptations of the Brain in Chronic Pain With Opioid Exposure NCT05463367 | Northwestern University | Phase 2 |
| Completed | Radiofrequency (RF) Ablation Prospective Outcomes Study NCT04673032 | Boston Scientific Corporation | — |
| Unknown | Ultrasound Versus Fluoroscopy Guided Superior Hypogastric Plexus Block in Cancer Bladder Patients NCT05083702 | National Cancer Institute, Egypt | N/A |
| Completed | Investigating Biological Targets, Markers, and Intervention for Chronic Pain NCT04625504 | Vanderbilt University Medical Center | N/A |
| Unknown | Lidocaine and Magnesium and Ketamine in Gynecological Surgery NCT04622904 | Aretaieion University Hospital | N/A |
| Completed | Internet-based Cognitive Behavioral Therapy and Physiotherapy in Persons With Chronic Widespread Pain NCT04624139 | Vastra Gotaland Region | N/A |
| Completed | Mobilization With Movement in Carpal Tunnel Syndrome. NCT04733209 | İSMAİL CEYLAN | N/A |
| Completed | How Does Mindfulness Meditation Buffer the Negative Effects of Pain and Suffering in the COVID-19 World? (Pain NCT04602286 | The University of Queensland | N/A |
| Unknown | Clinical Trial of Ultrasound Combined With Computed Tomography Guided Lumbar Sympathetic Ganglion Block NCT04167956 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Unknown | Pain and Opioid Management in Older Adults NCT05037682 | University of Oklahoma | N/A |
| Active Not Recruiting | SPRINT: Signature for Pain Recovery IN Teens NCT04285112 | Stanford University | — |
| Completed | Ibuprofen and Neural Mobilization Treatment in Carpal Tunnel Syndrome. NCT04328805 | Universidad Europea de Madrid | Phase 4 |
| Completed | Changes in Affective Pain Processing in Human Volunteers NCT04280796 | susanne becker | N/A |
| Completed | Investigation of the Effectiveness of a Structured Squat-based Program in Knee Osteoarthritis Rehabilitation NCT04588558 | Istanbul Medipol University Hospital | N/A |
| Terminated | A Group Therapy Based on the Bio-psycho-social Treatment Approach for Women With Chronic Pelvic and Chronic Be NCT04057664 | Swiss Paraplegic Research, Nottwil | — |
| Unknown | The Effect of Intradermal Local Anesthetic Injection in FBSS (Failed Back Surgery Syndrome) NCT04268602 | Haydarpasa Numune Training and Research Hospital | N/A |
| Completed | Real-World Experience of Patients Treated for Musculoskeletal Injuries With SAM in Routine Care NCT05254470 | ZetrOZ, Inc. | — |
| Completed | Analgesic Effect of Resistance Training for Breast Cancer Survivors NCT04509284 | Aalborg University | N/A |
| Recruiting | Using Technology to Track Pain and Pain-related Outcomes NCT04267588 | Johns Hopkins University | — |
| Completed | An Evaluation of a Public Health Campaign Related to Persistent Pain in the United Kingdom NCT06151678 | Teesside University | — |
| Unknown | Back Pain and Arthroplasty in Orthopedists NCT04505332 | Uludag University | N/A |
| Unknown | Paracetamol Discontinuation in the Elderly After Long-term Consumption NCT04523740 | University Hospital Bispebjerg and Frederiksberg | N/A |
| Unknown | Transitioning to a Valve -Gated Intrathecal Drug Delivery System NCT04312685 | Bux, Anjum, MD | N/A |
| Completed | Comparison of DTM™ SCS Therapy Combined With Conventional Medical Management (CMM) to CMM Alone in the Treatme NCT06442410 | MedtronicNeuro | N/A |
| Completed | Spinal Cord Stimulation in the Treatment of Chronic, Intractable Pain Using the Nalu™ Neurostimulation System NCT04503109 | Nalu Medical, Inc. | N/A |
| Completed | The Effects of Relaxation Techniques on Pain, Fatigue and Kinesiophobia in Multiple Sclerosis Patients: A Thre NCT04833673 | Hacettepe University | N/A |
| Unknown | Long Term Use of a High Energy Pulsed Heating Device in the Management of Chronic Pain NCT04407884 | Soovu Labs Inc. | N/A |
| Completed | Project Relief: Developing Brain Stimulation as a Treatment for Chronic Pain NCT04156802 | Wake Forest University Health Sciences | N/A |
| Unknown | Upper Extremity paın and Ultrasound Use NCT04477135 | Nefise Nazlı YENIGUL | N/A |
| Withdrawn | Intradural Percutaneous Stimulation NCT03380104 | Matthew Howard | N/A |
| Unknown | Pain Sensitivity Evaluation in Respiratory Patients NCT04297098 | Universidad de Granada | — |
| Completed | myoActivation® for Chronic Pain in a Marginalized Population NCT04261959 | University of British Columbia | — |
| Active Not Recruiting | Sleep Intervention for Chronic Insomnia Using Virtual Reality Pilot Study NCT04253691 | University of Missouri-Columbia | N/A |
| Completed | The Effect of Palmitylethanolamide on Central and Peripheral Sensitization After Heat-induced Hyperalgesia NCT04662827 | Medical University of Graz | N/A |
| Completed | Establishing Clinical Utility of a New Diagnostic Test for Patients Suffering From Pain: A CPV® Randomized Con NCT04266821 | Qure Healthcare, LLC | N/A |
| Completed | Mobile-Based Contingency Management to Promote Daily Self-monitoring in Primary Care Patients NCT03962491 | Virginia Commonwealth University | N/A |
| Completed | hBET for Pain and Sleep Feasibility NCT04176861 | University of Manchester | N/A |
| Unknown | Validity, Reliability and Responsiveness of Pain Sensitization Questionnaire NCT04162730 | Acibadem University | — |
| Completed | Injection of Dorsal Scapular n at Different Levels, Dose it Make Difference? NCT04693312 | Assiut University | Phase 2 / Phase 3 |
| Completed | Cooperative Pain Education and Self-management: Expanding Treatment for Real-world Access (COPES ExTRA) NCT03469505 | Yale University | N/A |
| Unknown | Can a Relaxometer Improve Cognitive Impairment of Fibromyalgia Patients NCT04170387 | Azienda Ospedaliera Universitaria Integrata Verona | N/A |
| Completed | Is it Necessary to Fix Mesh in Laparoscopic Hernia Repair NCT05152654 | Hitit University | N/A |
| Completed | Prevalence of Chronic Pain and Its Risk Factors After a Surgical Intensive Care Unit Stay. Prospective Observa NCT04164342 | University Hospital, Angers | N/A |
| Unknown | Nutraceuticals and Functional Foods NCT05509075 | University of Catanzaro | — |
| Unknown | Intercostobrachial Nerve Sparing to Reduce Post-Surgical Pain NCT03421522 | McMaster University | N/A |
| Completed | Ketamine to Improve Recovery After Cesarean Delivery - Part 1 NCT04037085 | Grace Lim, MD, MS | Phase 2 |
| Completed | Linking Epigenomics With Prescription Opioid Abuse and High Impact Musculoskeletal Pain NCT03947749 | University of Florida | — |
| Completed | Pain Neuroscience Education in Patients with Fibromyalgia NCT04050839 | Kutahya Health Sciences University | N/A |
| Completed | Assessing Opioid Care Practices Using CPV Patient Simulation Modules NCT04080037 | Qure Healthcare, LLC | N/A |
| Completed | Meditation Based Lifestyle Modification in Chronic Pain NCT04089618 | Diakonie Kliniken Zschadraß | N/A |
| Recruiting | Pain and Weight Treatment: Development and Trial of PAW NCT04046562 | Connecticut Children's Medical Center | N/A |
| Completed | The Impact of Music on Nociceptive Processing NCT04087564 | Brigham and Women's Hospital | N/A |
| Completed | Pawsitive Impacts of Therapy Dog Visits NCT04727749 | University of Saskatchewan | N/A |
| Completed | Post-market, Randomized, Controlled, Prospective Study Evaluating Intrathecal Pain Medication (IT) Versus Conv NCT04096391 | Evolve Restorative Center | N/A |
| Completed | The Turkish Cross-Cultural Adaptation, Validity and Reliability of VMPCI NCT04258384 | Yeditepe University | — |
| Withdrawn | Phenol Neurolysis of Genicular Nerves for Chronic Knee Pain NCT03973177 | Northwestern University | Phase 4 |
| Recruiting | Evaluate the Impact of Targeted Physical Activity on Clinically Debilitated Dialysis Patients. NCT06374537 | University of Illinois at Chicago | N/A |
| Completed | Effects of Motor Imagery and Action Observation Training on Pain Perception in Patients With Chronic Neck Pain NCT03905577 | Universidad Autonoma de Madrid | N/A |
| Completed | Chronic Pain and Minor Breast Cancer Surgery NCT03912948 | Institut Claudius Regaud | — |
| Unknown | Noninvasive Brain Stimulation for Pain Relief NCT04283643 | University of Virginia | N/A |
| Completed | Audio-visual Stimulation: Sleep Dose Response NCT03569865 | University of Washington | N/A |
| Terminated | Burst Spinal Cord Stimulation (Burst-SCS) Study NCT03718325 | University of Michigan | N/A |
| Unknown | Impact of the Use of FeelWell™ Compression Garment on Individuals With a BMI ≥35 NCT03798873 | Feelwell Compression | N/A |
| Completed | Activate For Life: mHealth Intervention To Address Pain And Fatigue In Low-income Older Adults Aging In Place NCT03853148 | Medical University of South Carolina | N/A |
| Unknown | The Effect of Chronic Pain Relief Over Knee Joint Area by Gua Sha Therapy NCT03821194 | Taipei Veterans General Hospital, Taiwan | N/A |
| Completed | Oldpain2go®: an Exploratory (Pre-Feasibility) Study. NCT03804567 | Teesside University | N/A |
| Completed | Comparison of Respiratory Muscle, Pain, Functional Performance and Cognitive Status in Obstructive Lung Diseas NCT04048408 | Hacettepe University | — |
| Completed | Bowel ENDOmetriosis; Evaluation of Diagnostics and Quality of Life NCT03779256 | Oslo University Hospital | — |
| Completed | Persistant Post-mastectomy Pain in Breast Cancer : Incidence and Risk Factors NCT04676438 | Moroccan Society of Surgery | — |
| Unknown | Subjective Observational Study of Patients Using Transdermal Cream Medication And/Or Transdermal Patches With NCT03768011 | Data Collection Analysis Business Management | — |
| Completed | Omnitram Safety and Efficacy in the Treatment of Diabetic Neuropathy NCT03664921 | Syntrix Biosystems, Inc. | Phase 2 |
| Completed | Pain Management Support Study for Cancer Survivors NCT03782506 | Drexel University | N/A |
| Completed | Qualitative Study for Pain Measurement Using Innovative Health Technology NCT03727373 | University Hospital Schleswig-Holstein | — |
| Active Not Recruiting | EHR Precision Drug Treatment in Neonates NCT04850079 | Children's Hospital Medical Center, Cincinnati | — |
| Completed | Platelet Rich Plasma Versus Radio Frequency for Chronic Knee Arthritis NCT03886142 | Assiut University | N/A |
| Completed | Association of Acupuncture and Cupping in Advanced Knee Osteoarthritis NCT04168593 | University of Sao Paulo General Hospital | N/A |
| Completed | Evaluation of Specialized Water Dance Intervention NCT03908801 | Region Örebro County | N/A |
| Withdrawn | Ketamine Sickle Cell Disease NCT03502421 | University of South Florida | Phase 3 |
| Completed | Internet-based Cognitive Behavioral Therapy for Adolescents With Sleep Problems- a Feasibility Trial NCT04616157 | Karolinska Institutet | N/A |
| Completed | Intraoperative Versus CT Guided Celiac Plexus Neurolysis in Unresectable Pancreatic Cancer NCT03770247 | Mansoura University | N/A |
| Active Not Recruiting | Neurotechnology Following Traumatic Brain Injury NCT03649958 | Brain State Technologies, LLC | N/A |
| Completed | Utility of an APP for the Monitoring of Irruptive Oncological Pain NCT03597737 | Universitat Jaume I | N/A |
| Completed | Trial Applying Policy to Eliminate or Reduce Inappropriate Narcotics in the General-population NCT03400384 | Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal | N/A |
| Completed | Neuroimaging of Pain: Changes in Regional Brain Functioning Associated With Amplified Pain and Intensive Treat NCT03703921 | Children's Mercy Hospital Kansas City | — |
| Completed | CT-guided Ablation of the Ganglion Impar for Pelvic Tumors: Comparethe Addition of Ketorolac or Dexamethasone NCT03789227 | Mansoura University | N/A |
| Terminated | TransGrade Multimodal Neuromodulation of the Dorsal Root Ganglion Ensemble for Refractory Neuropathic Pain NCT03318250 | Guy's and St Thomas' NHS Foundation Trust | N/A |
| Completed | Buspirone for Opioid Tapering NCT03521960 | Johns Hopkins University | Phase 1 |
| Completed | Mindfulness for Pain Management in Patients With Cancer NCT03351010 | University of Michigan | N/A |
| Completed | Feasibility Study of a Modified Yoga Program for Elders NCT04343625 | University of Michigan | N/A |
| Completed | Hyperalgesia, Persistent Pain, and Fentanyl Dosing in On-Pump Coronary Artery Bypass Grafting NCT03450161 | University Hospital, Ghent | Phase 4 |
| Completed | The Sequelae of Mastectomy and Quadrantectomy Respect to the Reaching Movement in Breast Cancer Survivors NCT04145739 | University of Roma La Sapienza | N/A |
| Completed | Ultra-high Frequency (500 KHz) Spinal Cord Stimulation for Treatment of Chronic Back Pain or Lower Limb Pain NCT03543085 | GiMer Medical | N/A |