NCT04245098

Carpal Tunnel Syndrome and Amyloidosis

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Corporacion Parc Tauli · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Carpal tunnel syndrome has been suggested to be an early sign of amyloidosi. The investigators will evaluate tissue samples obtained from patients undergoing carpal tunnel release surgery for amyloid.

Detailed description

Carpal tunnel syndrome (CTS) can be caused by the deposition and accumulation of misfolded proteins called amyloid and is often an early manifestation of systemic amyloidosis. Patients with cardiac amyloidosis often have carpal tunnel syndrome that precedes cardiac manifestations by several years, and many patients will have undergone surgery for idiopathic carpal tunnel syndrome since the protein also deposits in the transversal carpal ligament of the hand. The investigators sought to identify the prevalence and type of amyloid deposits in patients undergoing carpal tunnel surgery and evaluate for cardiac involvement

Conditions

• Amyloidosis
• Carpal Tunnel Syndrome

Interventions

Type	Name	Description
PROCEDURE	Carpal tunnel syndrome surgery	Biopsy

Timeline

• Start date: 2020-01-08
• Primary completion: 2022-01-08
• Completion: 2023-01-08
• First posted: 2020-01-28
• Last updated: 2020-01-28

Locations

1 site across 1 country: Spain