NCT04491058

Assessment of Subsynovial Connective Tissue Thickness in Carpal Tunnel Syndrome

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 92 (actual)
• Sponsor: KU Leuven · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The general aim of this research is to gain insight in the role of SSCT in the etiology and progression of CTS. We hypothesize that (degenerative) damage of the SSCT occurs early on in the pathogenesis of CTS. Fibrotic damage to the SSCT will lead to altered morphology and biomechanical characteristics. This eventually may lead to damage of the median nerve. To examine the SSCT an ultrasound technique described by Van Doesburg et al. 2012 will be used First, the reliability of the US technique to characterize morphology of the SSCT will be investigated. Secondly, cross-sectional data will be collected in healthy subjects and CTS patients to provide descriptive parameters and to describe differences between patients and controls. In the final part a prospective study will be conducted to look at changes of SSCT thickness over time and after treatment.

Conditions

• Carpal Tunnel Syndrome

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	SSCT thickness measurement	Thickness measurement with ultrasound

Timeline

• Start date: 2020-08-11
• Primary completion: 2024-05-06
• Completion: 2024-05-06
• First posted: 2020-07-29
• Last updated: 2025-02-21

Locations

1 site across 1 country: Belgium