NCT05852288

Role of Inflammation in Carpal Tunnel Syndrome

Role of Inflammation in Carpal Tunnel Syndrome: A Prospective Cohort Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 50 (estimated)
• Sponsor: Ahram Canadian University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

This study aims to investigate the role of inflammation in carpal tunnel syndrome (CTS) using a prospective cohort study design. The study will involve a sample of at least 50 individuals with CTS who will undergo a comprehensive clinical and biochemical evaluation to assess the role of inflammation in CTS. The primary outcome measures include inflammatory markers, such as C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α), as well as clinical measures of CTS severity. Data will be analyzed using regression analysis to determine the relationship between inflammation and CTS. The study is expected to provide information on the role of inflammation in CTS and inform the choice of drug and concentration for transdermal drug administration.

Conditions

• Carpal Tunnel Syndrome
• Median Neuropathy, Carpal Tunnel

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Inflammatory markers	Participants in this cohort will undergo a comprehensive clinical and biochemical evaluation to assess the role of inflammation in CTS. The evaluation will include assessments of inflammatory markers, such as C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α), as well as clinical measures of CTS severity.

Timeline

• Start date: 2023-05-15
• Primary completion: 2023-09-01
• Completion: 2023-09-15
• First posted: 2023-05-10
• Last updated: 2023-05-10

Locations

1 site across 1 country: Egypt