NCT03205683

Intraneural Facilitation as a Treatment for Carpal Tunnel Syndrome

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Loma Linda University · Academic / Other
• Sex: All
• Age: 19 Years – 74 Years
• Healthy volunteers: Accepted

Summary

We hypothesize that a standard course of INF can result in significant improvement in CTS as measured by clinical, electrodiagnostic, or ultrasound measures.

Detailed description

INF is a novel non-invasive therapy based on the principle of restoring vascular function at the capillary level in peripheral nerve. his therapy has been shown to improve clinical function in patients with diabetic-associated polyneuropathy, a model for various forms of ischemic neuropathy. CTS is a common condition where regional compression at the wrist results in ischemic focal demyelination of the distal median nerve. This results in sensory dysfunction, pain, and eventually axon loss and weakness if the compression is sufficiently severe and prolonged. Standard therapy for CTS includes wrist splints, regional lidocaine injections, ergonomic adjustments, various forms of occupation therapy, and ultimately surgical release of the carpal tunnel ligament. However, all of these are either temporary in their effect or invasive. The diagnosis of CTS relies on clinical, electrodiagnostic or NCS, and ultrasound methods.

Conditions

• Carpal Tunnel Syndrome

Interventions

Type	Name	Description
OTHER	Intraneural facilitation (INF)	INF is a novel non-invasive therapy based on the principle of restoring vascular function at the capillary level in peripheral nerve.
OTHER	Sham INF	Will be performed by a different therapist than actual INF. The patient will be asked to do the following combination of passive range of motion (PROM) and active ROM activities to promote blood flow in the affected arm.

Timeline

• Start date: 2018-01-29
• Primary completion: 2019-02-22
• Completion: 2019-02-22
• First posted: 2017-07-02
• Last updated: 2019-09-10

Locations

1 site across 1 country: United States