| Not Yet Recruiting | The Coma Family Program (COMA-F): A Resilience Program for Caregivers of Patients With Severe Acute Brain Inju NCT07331324 | Massachusetts General Hospital | N/A |
| Not Yet Recruiting | The Association Between Tau & GFAP and Postoperative Neurological Impairment in Patients Undergoing Cardiac Su NCT06899971 | Boston Children's Hospital | — |
| Not Yet Recruiting | fNIRS for Disorders of Consciousness NCT07485361 | University of California, Los Angeles | — |
| Not Yet Recruiting | Effects of Virtual Reality With Multisensory Stimulation on Emotional and Behavioral Disorders in Individuals NCT07371260 | Hopital La Musse | N/A |
| Not Yet Recruiting | Neuroprotective Effect of Mild Hypothermia Versus Normothermia During Cardiopulmonary Bypass of Coronary Arter NCT07316868 | Turku University Hospital | N/A |
| Recruiting | Multifaceted Intervention to Restore Resilience and Overcome Risk NCT06988787 | Icahn School of Medicine at Mount Sinai | N/A |
| Recruiting | Paired Vagus Nerve Stimulation in Mobilization of Patients With Prolonged Disorders of Consciousness NCT06930716 | Icahn School of Medicine at Mount Sinai | N/A |
| Enrolling By Invitation | A Feasibility Study in Combat Athletes With Mild Traumatic Brain Injury NCT06901310 | Michael Harl | N/A |
| Recruiting | Q Therapeutic System for Chronic Stroke Recovery NCT06979466 | Burke Rehabilitation Hospital | N/A |
| Not Yet Recruiting | The Study on the Efficacy of tDCS Stimulation of the Cerebellum Combined With XingNaoJing Injection in Patient NCT06927336 | The Second Affiliated Hospital of Kunming Medical University | Phase 4 |
| Active Not Recruiting | Cognitive Functions in Severe Acquired Brain Injury After Cranioplasty NCT06895109 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Active Not Recruiting | Early Myofascial Manual Treatment in Subjects With Spasticity Following Acquired Brain Injury NCT06898242 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | N/A |
| Not Yet Recruiting | Pain Control and Quality of Recovery After Intravenous Methadone Versus Intravenous Remifentanil in Craniotomy NCT06810336 | University of Virginia | EARLY_Phase 1 |
| Recruiting | University of Central Florida CereBank NCT06876857 | University of Central Florida | — |
| Not Yet Recruiting | Expanding Access to mTBI Treatment for Veterans and Service Members With Co-occurring Substance Use NCT06620900 | Shepherd Center, Atlanta GA | N/A |
| Not Yet Recruiting | Validation of a 3D Instrumented Serious Game to Evaluate Upper Limb Impairments in Children With Neuromotor Di NCT06774456 | University Hospital, Geneva | N/A |
| Not Yet Recruiting | Protective Effect of Angong Niuhuang Against Negative Inflammatory Response and Neurologic Dysfunction After C NCT06723366 | Nanjing Medical University | N/A |
| Recruiting | ACT for Mental Health in Neurological Disorders NCT06897553 | Bielefeld University | N/A |
| Recruiting | Motor Performance Improvement After Visual Rehabilitation NCT06698172 | Instituto de Investigación Sanitaria Aragón | N/A |
| Enrolling By Invitation | Somatic and Ear Acupuncture for Dysphagia Rehabilitation and Decannulation After Severe Acquired Brain Injurie NCT06888219 | Fondazione Don Carlo Gnocchi Onlus | N/A |
| Recruiting | Feasibility and Safety of Intranasally Administered Breast Milk in HIE NCT06747260 | Semmelweis University | EARLY_Phase 1 |
| Not Yet Recruiting | Acquired Brain Injury and Neurorehabilitation: the Influence of Psychological Characteristics NCT06661512 | Institut Guttmann | — |
| Recruiting | Development and Implementation of an Intervention Enhancing Involvement of Relatives to Patients With Acquired NCT06796335 | Rigshospitalet, Denmark | — |
| Recruiting | Prognostic Value of Neurometabolic Networks in CRC (PVNM-CRC) NCT06930586 | The First Affiliated Hospital of Zhengzhou University | — |
| Completed | Protein S100B Versus Neutrophils/Lymphocytes Ratio in Early Prediction of Brain Injury NCT07093723 | Tanta University | — |
| Recruiting | Evaluation of the Impact of the AVanCer Program Provided by the ARRPAC Day Center NCT05795686 | Hospices Civils de Lyon | N/A |
| Unknown | Macro- and Microcirculation Crosstalk in Brain-damaged Patients Under Anesthesia or in Intensive Care NCT05285514 | Assistance Publique - Hôpitaux de Paris | — |
| Recruiting | Innovative Multimodal and Attention Training to Improve Emotion Communication in Veterans With TBI and PTSD NCT05478759 | VA Office of Research and Development | N/A |
| Recruiting | Comparing Telehealth to In-person a Combined Metacognitive Training in Veterans With mTBI/PTSD NCT05380050 | VA Office of Research and Development | N/A |
| Completed | Brain Death and Organ Donation in Tunisian Intensive Care Units NCT06948669 | Faculty of Medicine, Sousse | — |
| Withdrawn | Whole-Body Hypothermia for Neonates With Hypoxic-Ischemic Encephalopathy(HIE) NCT05581927 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | N/A |
| Recruiting | Electrocorticographic Monitoring of Brain Retraction Injury (EMBRI) NCT06409806 | University College, London | N/A |
| Active Not Recruiting | NRF for Improved Re-Entry Outcomes for Offenders With Brain Injury (Brain Injury RE) NCT05708092 | Icahn School of Medicine at Mount Sinai | N/A |
| Recruiting | Biofeedback for Hemianopia Vision Rehabilitation NCT05397873 | University Health Network, Toronto | N/A |
| Unknown | Biofeedback Gait Retraining for Stiff Knee Gait Correction NCT05105763 | Kessler Foundation | N/A |
| Unknown | Effectiveness of Aquatic Theraphy in Spasticity: Watsu and Halliwick NCT05151497 | University of Cadiz | N/A |
| Completed | Implementation of the Pittsburgh Infant Brain Injury Score NCT05034718 | University of Pittsburgh | N/A |
| Completed | Relationship Between Intracranial Blood Flow and Peripheral Perfusion in Patients With Craniocerebral Injury NCT06016751 | Peking Union Medical College Hospital | — |
| Completed | Development and Validation of Automated Indicators on the Appropriateness of Oral Anticoagulant Prescriptions NCT02898090 | University Hospital, Bordeaux | — |
| Terminated | Comparison of Two Initial Evaluation Scales of the Severity of Brain Injury Adults Patients on the Neurologica NCT03157453 | Poitiers University Hospital | — |
| Completed | Motivation and Self-awareness in Acquired Brain Injury (ABI) NCT02913755 | University of Glasgow | N/A |
| Completed | tES With Random Noise Stimulation Applied to Children With Brain Injury NCT02656433 | Spanish Foundation for Neurometrics Development | N/A |
| Completed | Therapeutic Hypothermia and eArly Waking NCT03065946 | Mid and South Essex NHS Foundation Trust | — |
| Completed | Prediction of Brain Injury in Premature Infants NCT02814383 | Baylor College of Medicine | — |
| Completed | Laughter Therapy Effects on Mood, Stress and Self-efficacy in People With Neurological Diseases. NCT02750982 | Brown, Theodore R., M.D., MPH | N/A |
| Completed | Assessment and Rehabilitation of Central Sensory Impairments for Balance in mTBI NCT02748109 | Oregon Health and Science University | N/A |
| Unknown | Efficacy of an Early Rehabilitation on Decannulation Time of Patients With Severe Acquired Brain Injury NCT02990871 | Ospedale Generale Di Zona Moriggia-Pelascini | — |
| Unknown | Injectable Collagen Scaffold™ Combined With MSCs Transplantation for Brain Injury NCT02767817 | Chinese Academy of Sciences | Phase 1 |
| Unknown | A Study of IBRF Disorders of Consciousness Advanced Care/MultiModal Care Protocol in Severe Disorders of Consc NCT02696512 | International Brain Research Foundation | Phase 1 / Phase 2 |
| Active Not Recruiting | GLP-1 and Hyperoxia for Organ Protection in Heart Surgery NCT02673931 | Rigshospitalet, Denmark | N/A |
| Unknown | Neuromonitoring in Patients During Aortic Valve Replacement NCT02697786 | Marija Bozhinovska | Phase 3 |
| Completed | S100 Biomarker in the Acute Management of Mild Head Injuries NCT02650765 | Tampere University Hospital | — |
| Completed | Electrophysiological Evaluation of Voluntary Attention NCT02567201 | Hospices Civils de Lyon | N/A |
| Unknown | Cough Assessment in Patients With Severe Acquired Brain Injury NCT02495558 | IRCCS San Camillo, Venezia, Italy | N/A |
| Completed | Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia Nervosa NCT02615119 | Laureate Institute for Brain Research, Inc. | N/A |
| Completed | Sub-Threshold Exercise Treatment for Adolescents With Sports Related Concussion NCT02710123 | University at Buffalo | N/A |
| Completed | Using Ferumoxytol-Enhanced MRI to Measure Inflammation in Patients With Brain Tumors or Other Conditions of th NCT02452216 | Michael Iv | EARLY_Phase 1 |
| Completed | Gastrointestinal Transit Time in Patients With Severe Acquired Brain Injury NCT02428790 | University of Aarhus | — |
| Completed | Early Stepping Verticalization in ICU for ABI Patients NCT02828371 | Ospedale Generale Di Zona Moriggia-Pelascini | N/A |
| Completed | Analysis of TCLT in TBI Patients: a Prospective, Randomized Controlled Trial NCT02393079 | University of Sao Paulo General Hospital | N/A |
| Completed | Evaluation Report of the Urea / Urine Creatinine as a Marker of Nutritional Status Predictive of ICU Care Asso NCT02911246 | Nantes University Hospital | — |
| Unknown | PariS -TBI Study: Paris Severe Traumatic Brain Injury Study - 8 Years NCT02050633 | Assistance Publique - Hôpitaux de Paris | — |
| Terminated | Pharmacokinetics and Clinical Response of Tolvaptan in Neurocritical Care Patients NCT02215148 | University of North Carolina, Chapel Hill | — |
| Completed | MIND (Management of Traumatic Brain Injury Diagnosis) NCT02262286 | Abbott Diagnostics Division | — |
| Unknown | Exploring the Effectiveness of Sensor-based Balance Training on Patient Outcome Measures NCT02777060 | University of Arizona | N/A |
| Unknown | The Effect of Dexmedetomidine to Cognition of Geriatrics in Prolonged Surgery NCT02123355 | Shaanxi Provincial People's Hospital | Phase 4 |
| Completed | Effects of Delayed Cord Clamp and/or Indomethacin on Preterm Infant Brain Injury NCT02221219 | Hong Huang | Phase 1 / Phase 2 |
| Completed | Combination Therapy of Cord Blood and G-CSF for Patients With Brain Injury or Neurodegenerative Disorders NCT02236065 | MinYoung Kim, M.D. | N/A |
| Unknown | NeuroAiD Safe Treatment Registry NCT02536079 | CHIMES Society | — |
| Completed | Myobloc Atrophy Study NCT02052024 | Georgetown University | Phase 4 |
| Unknown | Using Tablets for Upper Extremity Rehabilitation Post Acquired Brain Injury NCT02136433 | Sheba Medical Center | N/A |
| Completed | Effects of Viral Reactivation on Outcomes of Brain-injured Patients ( IBIS-VIRUS) NCT02003196 | Nantes University Hospital | — |
| Unknown | Evaluation of the Acceptability, Feasibility and Effectiveness of Two Methods of Involvement of Patients With NCT02023138 | Laval University | N/A |
| Completed | Use of the Passy Muir Swallowing Self Trainer NCT02848664 | James Madison University | — |
| Completed | Mechanical Ventilation in Brain-injured Patients NCT01885507 | Nantes University Hospital | — |
| Completed | Children With Hemiparesis Arm and Hand Movement Project (CHAMP Study) NCT01895660 | Virginia Polytechnic Institute and State University | Phase 2 |
| Completed | Criteria of Extubation Failure of Brain Injured Patients. Elaboration of a Prognostic Score. NCT02235376 | University Hospital, Clermont-Ferrand | — |
| Unknown | Remotely Deployed TBI Study NCT01882244 | VA Northern California Health Care System | N/A |
| Completed | Safety Study for Adolescents With Concussion NCT02714192 | University at Buffalo | N/A |
| Completed | Assessment of Dystussia in Traumatic Brain Injury NCT02240329 | University of Florida | EARLY_Phase 1 |
| Completed | Prospective Research in Infants With Mild Encephalopathy NCT01747863 | McGill University Health Centre/Research Institute of the McGill University Health Centre | — |
| Completed | Bilateral Movement Training for People With Stroke NCT02247674 | Chueh-Ho Lin | N/A |
| Completed | Early Verticalization in neuroICU With ERIGO: a Safety and Feasibility Study NCT02100592 | Ospedale Generale Di Zona Moriggia-Pelascini | Phase 1 / Phase 2 |
| Completed | The Effects of Mindfulness Based Stress Reduction on Patients With Traumatic Brain Injury NCT01613872 | Spaulding Rehabilitation Hospital | N/A |
| Terminated | Sevoflurane Sedation on Intra Cranial Pressure in Traumatic Brain Injury Patients NCT01374633 | Assistance Publique - Hôpitaux de Paris | Phase 2 |
| Unknown | The Evaluation of Balance Control by Quantification of Temporospatial Measures While Forward and Side Reaching NCT01451216 | Sheba Medical Center | — |
| Completed | Neural Bases of Cognitive Rehabilitation for Brain Injury NCT01120756 | VA Office of Research and Development | N/A |
| Completed | Vasospasm in Pediatric Traumatic Brain Injury NCT01461902 | Duke University | — |
| Completed | Cognitive Impairment Following Cardiac Arrest and Target Temperature Management NCT01946932 | Region Skane | N/A |
| Completed | Navigated Brain Stimulation in Diagnosis of Minimally Conscious State NCT01467908 | Clinical Institute of the Brain, Russia | N/A |
| Completed | Vestibular Consequences of Blast-related Mild Traumatic Brain Injury (TBI) NCT01021137 | VA Office of Research and Development | — |
| Completed | Applicability and Safety of Vibration Therapy in Intensive Care Unit (ICU) Patients NCT01286610 | Charite University, Berlin, Germany | N/A |
| Completed | Neuroendocrine Dysfunction in Traumatic Brain Injury: Effects of Testosterone Therapy NCT01201863 | Craig Hospital | Phase 4 |
| Unknown | Optimization of Human Cortical Stimulation NCT01198964 | University of Washington | — |
| Completed | Traumatic Brain Injury (TBI) Screening Instruments NCT00875329 | US Department of Veterans Affairs | — |
| Unknown | Effect of Rozerem on Sleep Among People With Traumatic Brain Injury NCT01207050 | Kessler Foundation | Phase 4 |
| Suspended | Efficacy Study of NH001 in Vegetative State & Minimally Conscious State Following a Traumatic Brain Injury NCT00761228 | NeuroHealing Pharmaceuticals Inc. | Phase 2 |
| Completed | Melatonin As A Novel Neuroprotectant In Preterm Infants- Dosage Study NCT00649961 | Imperial College London | Phase 2 |
| Completed | PariS-TBI Study : Paris Severe Traumatic Brain Injury Study NCT01437683 | Assistance Publique - Hôpitaux de Paris | — |
| Terminated | OSCAR - An Internet-based Supportive Coaching for Informal Caregivers of Adult Individuals With an Acquired Br NCT01112969 | University of Bern | Phase 2 |
| Completed | Training in Goal-directed Attention Regulation for Individuals With Brain Injury NCT01035606 | VA Office of Research and Development | N/A |
| Completed | Cerebral Antibiotics Distribution After Acute Brain Injury NCT01059890 | Poitiers University Hospital | Phase 1 |
| Completed | Amantadine for the Treatment of Traumatic Brain Injury Irritability and Aggression: A Multi-site Study NCT00779324 | Wake Forest University Health Sciences | N/A |
| Unknown | Evaluation the Intracranial Volume Pressure Response in Increased Intracranial Pressure NCT01126658 | Chang Gung Memorial Hospital | — |
| Completed | MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose Caffeine NCT00809055 | Washington University School of Medicine | Phase 4 |
| Completed | Duration of Hypothermia for Neuroprotection After Pediatric Cardiac Arrest NCT00797680 | University of Pittsburgh | Phase 2 |
| Completed | Safety of N-acetylcysteine in Maternal Chorioamnionitis (NAC in Chorio) NCT00724594 | Medical University of South Carolina | Phase 1 / Phase 2 |
| Completed | A Pilot Study of Rehabilitation Among Intensive Care Unit (ICU) Survivors: the RETURN Trial NCT00715494 | Vanderbilt University | N/A |
| Unknown | Improving Psychological Wellness After Acquired Brain Injury NCT00866632 | Toronto Rehabilitation Institute | N/A |
| Terminated | Heart Rate Variability (HRV) Among Children With Brain Damage NCT00746291 | Alyn Pediatric & Adolescent Rehabilitation Hospital | N/A |
| Completed | Motor Imagery Practice in Neurological Rehabilitation NCT00618085 | Nuffield Orthopaedic Centre NHS Trust | Phase 2 |
| Completed | Precedex Versus Propofol-Awakening for Reducing Brain Injury Expansion NCT00538616 | Carmelo Graffagnino | Phase 1 / Phase 2 |
| Completed | Estimating Volume Using LiDCO NCT00571441 | Duke University | — |
| Completed | Preconditioning With Hyperbaric Oxygen in Cardiovascular Surgery NCT00817791 | Xijing Hospital | N/A |
| Completed | Neuropsychological Cognitive Behavioral Therapy for Patients With Acquired Brain Injury NCT00596765 | Philipps University Marburg | N/A |
| Completed | Automated Chest Physiotherapy to Improve Outcomes in Neuro NCT00571623 | Duke University | — |
| Completed | Functional and Anatomical Magnetic Resonance Imaging (MRI) of Chronic Brain Injury and Hyperbaric Oxygen (HBO2 NCT01126515 | Intermountain Health Care, Inc. | — |
| Terminated | High-Dose Erythropoietin in Extremely Premature Infants to Prevent/Attenuate Brain Injury: A Phase II Study NCT00589953 | Atlantic Health System | Phase 2 |
| Completed | Bone Loss, Fractures, and Management of Bone Health in People With Stroke in Managed Rehabilitation Settings NCT00462683 | Northwestern University | — |
| Unknown | Respiratory Mechanics in Brain Injured Patients NCT00639990 | Università degli Studi dell'Insubria | N/A |
| Terminated | Investigating the Role of the Premotor Cortex in Higher Cognitive Functions NCT00842413 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Rehabilitation of Children With Multiple Disabilities NCT01379443 | Children's Treatment Network | Phase 1 |
| Completed | Methylphenidate (Ritalin) and Memory/Attention in Traumatic Brain Injury (TBI) NCT00453921 | Dartmouth-Hitchcock Medical Center | N/A |
| Terminated | Combining Observational and Physiologic Sedation Assessment Tools NCT00538369 | Duke University | Phase 4 |
| Completed | Home Based Exercise Program for Brain Injury Children NCT00338871 | Alyn Pediatric & Adolescent Rehabilitation Hospital | N/A |
| Completed | The Connection Between Gait Variability Parameters and Balance Performance in Children With Physical Disabilit NCT00338858 | Alyn Pediatric & Adolescent Rehabilitation Hospital | N/A |
| Unknown | Study of Bedside EEG to Evaluate Brain Injury in Premature Newborns NCT00516334 | Brigham and Women's Hospital | — |
| Completed | Genomics, Single Nucleotide Polymorphisms (SNPs), and Clinical Neonatology NCT00315263 | Children's Mercy Hospital Kansas City | — |
| Completed | The Erythropoietin NeuroProtective Effect: Assessment in CABG Surgery (TENPEAKS) NCT00336466 | University of Calgary | Phase 2 |
| Completed | A Prospective Trial of Elective Extubation in Brain Injured Patients. NCT00729261 | Mayo Clinic | Phase 1 |
| Completed | Hyperbaric Oxygen Therapy in Chronic Stable Brain Injury NCT00830453 | Intermountain Health Care, Inc. | Phase 2 |
| Completed | The Use of Low Molecular Weight Heparin in Traumatic Brain Injury NCT00170378 | Hennepin Healthcare Research Institute | Phase 4 |
| Completed | Alveolar Recruitment in Brain Injury NCT01159392 | Hospital Clinic of Barcelona | — |
| Completed | Genotype Influence on Recovery After Traumatic Brain Injury NCT00018499 | US Department of Veterans Affairs | — |
| Unknown | Study of the Approximate Entropy of Adrenocorticotropic Hormone and Cortisol Secretion in Patients With Head I NCT00006270 | National Center for Research Resources (NCRR) | — |
| Unknown | Phase I/II Study of Neuroendocrine Dysfunction in Patients With Closed Head Injuries NCT00006271 | National Center for Research Resources (NCRR) | — |
| Completed | Neuropsychiatric Evaluation of Healthy Volunteers and Adults With Schizophrenia NCT00001323 | National Institute of Mental Health (NIMH) | — |
| Available | Intermediate Size Patient Population Expanded Access Protocol to Evaluate HB-adMSCs for the Treatment of Patie NCT07164482 | Hope Biosciences Research Foundation | — |