NCT02236065

Combination Therapy of Cord Blood and G-CSF for Patients With Brain Injury or Neurodegenerative Disorders

A Pilot Study of Combination Therapy of Allogeneic Umbilical Cord Blood and Granulocyte-colony Stimulating Factor for Patients With Brain Injury or Neurodegenerative Disorders

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: MinYoung Kim, M.D. · Academic / Other
• Sex: All
• Age: 19 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

This open label trial is conducted to investigate the efficacy and safety of the combination therapy of allogeneic umbilical cord blood (UCB) and granulocyte-colony stimulating factor (G-CSF) for patients with brain injury or neurodegenerative disorders.

Detailed description

Current treatments for brain injury or neurodegenerative disorders are palliative rather than curative. Preclinical and some clinical studies suggest that UCB and G-CSF can be used as restorative approach for such disorders.

Conditions

• Brain Injury
• Cerebral Palsy
• Amyotrophic Lateral Sclerosis
• Parkinson's Disease

Interventions

Type	Name	Description
PROCEDURE	Umbilical cord blood therapy
BIOLOGICAL	Filgrastim

Timeline

• Start date: 2014-08-01
• Primary completion: 2016-07-01
• Completion: 2016-07-01
• First posted: 2014-09-10
• Last updated: 2017-10-12

Locations

1 site across 1 country: South Korea