NCT00571441

Estimating Volume Using LiDCO

Estimating Volume Using LiDCO Versus Other Measures of Volume

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 34 (actual)
• Sponsor: Duke University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

We hypothesize that the stroke volume variation measured using the commercially available LiDCO monitor provides a reasonable estimate of volume when compared to standard measures. This study will collate data that is already being collected by the bedside nurses.

Detailed description

Objective: To compare measurement of stroke volume variance with intake/output measurements, weight, BUN/Creatnine values, and central venous pressure. Design: Non-experimental, non-randomized observational comparative study. Setting: The sixteen bed Neurocritical Care Unit at Duke University Hospital. Patients: 45 adult (over 18 years) subjects with intracranial pathology who require volume resuscitation. Only patients with current LiDCO monitoring will be considered eligible for inclusion in the study. Interventions: This is an observational study. Subjects will receive standard-of-care treatment without additional intervention. Data Analysis: All data will be collected by the principal investigator / study coordinator. Personal patient information will be removed (deidentified) from the permanent data collection records to protect patient confidentiality. Data collected will be entered into a Microsoft Excel electronic spreadsheet and will be saved on a USB Disk drive to be stored in a locked cabinet in the investigator's office. Statistical analysis using SAS v9.1, (Cary, NC) will be conducted with a level of significance set at .05 (alpha) using standardized comparative analysis techniques.

Conditions

• Brain Injury
• Ischemic Stroke
• Hemorrhagic Stroke

Timeline

• Start date: 2007-12-01
• Primary completion: 2008-09-01
• Completion: 2008-12-01
• First posted: 2007-12-12
• Last updated: 2016-01-21

Locations

1 site across 1 country: United States