NCT01946932

Cognitive Impairment Following Cardiac Arrest and Target Temperature Management

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 287 (actual)
• Sponsor: Region Skane · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a steering group approved substudy to the Target Temperature Management trial (TTM, ClinicalTrials.gov Identifier: NCT01020916). TTM compares the effect of two strictly controlled temperature regimes for survivors of out-of-hospital cardiac arrest. The primary aim of this sub-study is to compare the amount of cognitive impairment in cardiac arrest survivors treated with 33 degrees and 36 degrees and with a matched group of control patients with myocardial infarction. Our secondary aims are: * To investigate the impact of cognitive impairment on our patients' ability to participate in society and their health related quality of life. * To investigate the relationship between our patients cognitive impairments and their relatives/informants health related quality of life and feelings of burden. * To test the hypothesis that the simple cognitive screening battery used in the TTM main trial is sensitive enough to detect all patients with significant cognitive disability.

Conditions

• Heart Arrest
• Out-of-hospital Cardiac Arrest
• Cognition Disorders
• Brain Injury

Interventions

Type	Name	Description
OTHER	Temperature treatment

Timeline

• Start date: 2011-06-01
• Primary completion: 2013-11-01
• Completion: 2013-11-01
• First posted: 2013-09-20
• Last updated: 2013-12-05

Locations

20 sites across 5 countries: Denmark, Italy, Netherlands, Sweden, United Kingdom