NCT02767817

Injectable Collagen Scaffold™ Combined With MSCs Transplantation for Brain Injury

The Safety and Efficacy Assessment of Injectable Collagen Scaffold™ Combined With Mesenchymal Stem Cells Transplantation in Patients With Brain Injury

• Status: Unknown
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Chinese Academy of Sciences · Other Government
• Sex: All
• Age: 35 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to assess the safety and efficacy of injectable collagen scaffold combined with Mesenchymal stem cells (MSCs) transplantation in patients with brain injury.

Conditions

• Brain Injury

Interventions

Type	Name	Description
PROCEDURE	Stereotactic Hematoma Evacuation	Stereotactic intracranial hematoma and insert the drainage tube to inhale haematoma. The drainage tube stayed in the position for 1-2 days until adequate drainage of hematomas, and then the drainage tube was pulled out.
BIOLOGICAL	MSCs Transplantation	Stereotactic intracranial hematoma and insert the drainage tube to inhale haematoma. The drainage tube stayed in the position for 1-2 days until adequate drainage of hematomas,and 10 million MSCs were transplanted into the hematoma cavity before the drainage tube was pulled out.
BIOLOGICAL	Injectable Collagen Scaffold with MSCs Transplantation	Stereotactic intracranial hematoma and insert the drainage tube to inhale haematoma. The drainage tube stayed in the position for 1-2 days until adequate drainage of hematomas, and injectable collagen scaffold combined with 10 million MSCs were transplanted into the hematoma cavity before the drainage tube was pulled out.

Timeline

• Start date: 2016-03-01
• Primary completion: 2021-12-01
• Completion: 2021-12-01
• First posted: 2016-05-10
• Last updated: 2020-12-23

Locations

1 site across 1 country: China