NCT06899971

The Association Between Tau & GFAP and Postoperative Neurological Impairment in Patients Undergoing Cardiac Surgery

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Boston Children's Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Patients born with heart defects often undergo surgical procedures on a heart lung machine. With improvements in medical and surgical management, their survival has significantly improved, but their brain insult has not been paid much attention. This study is to determine the relationship between specific proteins in the blood and brain injury in patients less than 18-year-old undergoing heart surgery.

Conditions

• Cardiac Surgery Requiring Cardiopulmonary Bypass
• Brain Injury
• Congenital Heart Defect

Interventions

Type	Name	Description
OTHER	Collecting discarded blood samples	Discarded blood samples will be collected from routine clinical labs collected before and after surgery.

Timeline

• Start date: 2026-05-01
• Primary completion: 2026-12-31
• Completion: 2027-12-31
• First posted: 2025-03-28
• Last updated: 2026-03-17

Locations

1 site across 1 country: United States