| Not Yet Recruiting | Stratification and Treatment in Early Psychosis Study -ASSIST NCT07326124 | University of Oxford | Phase 3 |
| Recruiting | Multimodal Intervention to Support Hospital-to-Community Transition in Bipolar Disorder NCT07213492 | McMaster University | N/A |
| Not Yet Recruiting | Online Intervention To Improve Motivation NCT07157293 | University of Alabama at Birmingham | N/A |
| Not Yet Recruiting | Cognitive Strategies in Early Psychosis 2 NCT07263022 | University of Minnesota | Phase 3 |
| Not Yet Recruiting | The Mouth Matters in Mental Health Trial -2 NCT07470437 | Lancashire and South Cumbria NHS Foundation Trust | N/A |
| Not Yet Recruiting | Pilot Study of Sensor-Informed Smartphone-based Mental Health Interventions for Mood in Early Psychosis NCT07503093 | Mclean Hospital | N/A |
| Recruiting | Effects of Action-Based Cognitive Remediation on Substance Misuse in Early Phase Psychosis NCT07056894 | Nova Scotia Health Authority | N/A |
| Not Yet Recruiting | Improving Health Literacy in Patients With Schizophrenia Spectrum Disorder NCT07488156 | Louisiana State University Health Sciences Center in New Orleans | N/A |
| Not Yet Recruiting | Comparison of Accelerated Intermittent Theta Burst Stimulation vs High Frequency Transcranial Magnetic Stimula NCT07445620 | All India Institute of Medical Sciences, Bhubaneswar | N/A |
| Not Yet Recruiting | What is the Feasibility of Narrative Exposure Therapy (NET) for People Experiencing Psychosis? NCT07237529 | University of Nottingham | N/A |
| Not Yet Recruiting | Stratification and Treatment in Early Psychosis Study - ENHANCE NCT06778564 | University of Oxford | Phase 3 |
| Not Yet Recruiting | Strategic Timing of Resistance Training to Guard Against Antipsychotic-Induced Metabolic Syndrome NCT07386483 | University College Dublin | N/A |
| Recruiting | Acceptability, Feasibility and Preliminary Outcomes of the Kiso Mind App for Outpatients With Schizophrenia Sp NCT07395206 | Charite University, Berlin, Germany | N/A |
| Recruiting | Precision Brain Stimulation to Reduce Cannabis Craving in Schizophrenia NCT07196462 | Vanderbilt University Medical Center | N/A |
| Recruiting | Acute Psychiatric Care at Home for Lower-risk Patients With Acute Psychiatric Illness Who Require Inpatient Ca NCT07364825 | Brigham and Women's Hospital | N/A |
| Not Yet Recruiting | Assessment and Evolution of Narrative Identity and Its Relationship to Subjective Multidimensional Well-being NCT07330843 | Centre Hospitalier Universitaire de Nīmes | — |
| Not Yet Recruiting | A Case Series of Culturally-adapted CBTp for Black People in the UK NCT07252206 | University of Manchester | N/A |
| Not Yet Recruiting | Testing the Efficacy of the Cannabis Clinic for Patients With Psychosis (CCP) Intervention for Cannabis Use Re NCT07245212 | King's College London | N/A |
| Not Yet Recruiting | Narrative Identity and Its Relationship to Subjective Multidimensional Well-being in First Episode Psychosis NCT06464848 | Centre Hospitalier Universitaire de Nīmes | — |
| Not Yet Recruiting | Early Psychosis: Investigating Cognition NCT07196423 | University of Nottingham | N/A |
| Recruiting | Immune Mechanisms of Antipsychotic Treatment Response NCT06687694 | King's College London | — |
| Recruiting | Mentalization Based Treatment (MBT) in Help Seeking Youths With a Clinical High-Risk Condition for Psychosis ( NCT07093671 | Marco Armando | N/A |
| Not Yet Recruiting | A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzhei NCT06947941 | Bristol-Myers Squibb | Phase 3 |
| Recruiting | Study on the Use of Exergames to Support Older Adults With Psychosis NCT07060742 | Tobias Melcher | N/A |
| Not Yet Recruiting | Enhancing Comprehension of Consent in Patients With Psychotic Disorders NCT06975670 | Makerere University | N/A |
| Not Yet Recruiting | DIALOG: Understanding Disorganisation: A Language-focused Global Initiative in Psychosis NCT06978465 | Douglas Mental Health University Institute | — |
| Recruiting | A Novel Blood Test as a Biomarker in Mental Health NCT06856161 | Fraser Health | — |
| Recruiting | Cannabis Potency Effects on Brain White Matter in Early Phase Psychosis NCT07001878 | Nova Scotia Health Authority | Phase 4 |
| Active Not Recruiting | Youth Nominated Support Team NCT05558332 | University of California, Irvine | N/A |
| Recruiting | Enhancing Rehabilitation for Veterans With Serious Mental Illness NCT06586164 | VA Office of Research and Development | N/A |
| Active Not Recruiting | Imagery Rescripting as a Treatment for Early Psychosis NCT06539780 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Recruiting | A Mental Health Services Engagement Program for Racial and Ethnic Minority Young Adults NCT06508450 | New York University | N/A |
| Recruiting | Virtual Reality and Artificial Intelligence in Treatment for Patients With Psychosis NCT06728241 | Oslo University Hospital | N/A |
| Recruiting | Ketosis Impact on Signs & Symptoms of Schizophrenia and Bipolar disorderS NCT06426134 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Not Yet Recruiting | Individual Placement and Support and/or Cognitive Remediation Therapy Added to TAU in Patients With Early Schi NCT03974620 | Pakistan Institute of Living and Learning | N/A |
| Withdrawn | The Sub-Sero Study NCT03994965 | Bjorn H. Ebdrup | Phase 2 |
| Not Yet Recruiting | VR Based Therapy to Treat Anxiety in Dual Diagnosis NCT06315660 | Mental Health Centre Sct. Hans | N/A |
| Completed | DMHI for At-Risk College Students NCT06608498 | University of Washington | N/A |
| Recruiting | Clozapine-related Immunodeficiency in Parkinsons Disease NCT06634641 | Centre Hospitalier Universitaire, Amiens | Phase 4 |
| Not Yet Recruiting | The Personalized Psychological Treatment for Psychosis NCT06603922 | Polish Academy of Sciences | N/A |
| Not Yet Recruiting | Evaluating the Effects of Adjunctive Aripiprazole on Weight and Metabolic Outcomes in Females NCT06590298 | Universiti Putra Malaysia | Phase 4 |
| Enrolling By Invitation | Open Label Extension Study of NCT06221852 NCT06558201 | Mclean Hospital | N/A |
| Not Yet Recruiting | A Pilot Trial of Tapering Antipsychotics for Patients in Remitted Psychosis Co-administering With N-Acetylcyst NCT06546475 | National Taiwan University Hospital | Phase 4 |
| Recruiting | Cerebellar Modulation of Cognition in Psychosis NCT06107764 | Mclean Hospital | N/A |
| Recruiting | Investigating the Effect of a Single-dose of Levetiracetam on Brain Function, Chemistry and Cognitive Performa NCT06224530 | King's College London | N/A |
| Recruiting | Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health Trajectories NCT06978452 | Douglas Mental Health University Institute | — |
| Not Yet Recruiting | Focus Groups on Cognitive Function in Psychosis NCT06364241 | King's College London | — |
| Recruiting | Predicting Psychotic Relapse Using Speech-Based Early Detection NCT06978894 | Douglas Mental Health University Institute | — |
| Recruiting | A Probiotic Strategy for Antipsychotic-induced Metabolic Dysfunction NCT06729671 | University College Cork | N/A |
| Enrolling By Invitation | Magnetoencephalography in Psychosis Program NCT06978881 | Douglas Mental Health University Institute | — |
| Not Yet Recruiting | Belief-updating, Speech and Psychosis NCT06042712 | King's College London | — |
| Recruiting | Effects of Online Metacognitive Training Group on Distressing Beliefs NCT06703827 | City, University of London | N/A |
| Withdrawn | Sleep Quality, Cognitive Performance, and Computerized Cognitive Training NCT06328140 | George West Mental Health Foundation d/b/a Skyland Trail | — |
| Recruiting | Culturally Adapted Psychosocial Interventions for Early Psychosis in a Low-resource Setting NCT05814913 | Pakistan Institute of Living and Learning | N/A |
| Recruiting | Learning Through Play Plus for Psychosis NCT06301347 | Pakistan Institute of Living and Learning | N/A |
| Recruiting | Ketogenic and Nutritional Interventions for First Episode Bipolar Disorder NCT06221852 | Mclean Hospital | N/A |
| Recruiting | The Effectiveness of Individualized Imagery Scripts on Sleep, Psychosis, and Suicidality Among Inpatients With NCT06194344 | The University of Texas Health Science Center, Houston | N/A |
| Active Not Recruiting | REWRITALIZE Your Recovery - Evaluation of a Creative Writing Group Intervention NCT06251908 | Amager Hospital | N/A |
| Recruiting | Enhanced Coordinated Specialty Care for Early Psychosis NCT06071858 | Mclean Hospital | N/A |
| Recruiting | Study of Language Disorders and Interactions Between Mnesic Capabilities and Semantic Competencies in Patients NCT06036316 | Centre Psychothérapique de Nancy | N/A |
| Recruiting | HYEEG Discourse in Psychosis: A Neurobehavioural Study NCT06978803 | Douglas Mental Health University Institute | — |
| Active Not Recruiting | CLinical Utility of Early Intervention Including the 5-Step Precision Medicine (5SPM) Method in First-episode NCT06453174 | Instituto de Investigación Biomédica de Salamanca | — |
| Completed | KF2022#3-trial: Effect of Tea and Cola Beverage on Absorption of Risperidone Oral Solution NCT06218979 | Helsinki University Central Hospital | Phase 1 |
| Completed | Enhancing Mental Health Outcomes for Patients With Psychosis in Malawi Through Community-based Rehabilitation NCT06080477 | University of North Carolina, Chapel Hill | N/A |
| Unknown | Multidisciplinary Design to Optimize Schizophrenia Treatment Based on Multi-omics Data and Systems Biology Ana NCT06060886 | Consorcio Centro de Investigación Biomédica en Red (CIBER) | Phase 4 |
| Recruiting | Combining mHealth and Nurse-delivered Care to Improve the Outcomes of People With Serious Mental Illness in We NCT05703711 | University of Washington | N/A |
| Unknown | Effect of Acceptance and Commitment Therapy on Psychotic Severity NCT06160869 | Port Said University | N/A |
| Recruiting | Effect of Nutritional Counseling on Anthropometry and Biomarkers in Patients Diagnosed With Schizophrenia/Psyc NCT06197048 | Vestre Viken Hospital Trust | N/A |
| Completed | Physical Activity Level in Psychosis Patients NCT06408740 | Bandırma Onyedi Eylül University | — |
| Recruiting | Strengthening Care in Collaboration With People With Lived Experience of Psychosis in Uganda NCT05863572 | George Washington University | N/A |
| Terminated | Psychological Treatment in Psychiatric Inpatient Care NCT06012981 | Uppsala University | N/A |
| Completed | Optimizing Mental Health for Young People at Clinical High Risk for Psychosis (CHR) NCT05757128 | Centre for Addiction and Mental Health | N/A |
| Completed | Long-acting Injectable Antipsychotics for Mental Ill-Health in Pregnancy and Postpartum NCT05766007 | University of Liverpool | — |
| Recruiting | Real-life Assessment of Brexpiprazole (Rexulti) in Schizophrenia and in Depressive Disorders NCT05962216 | Dr. Albert Kar-Kin Chung | — |
| Completed | mHealth for Psychosis Help-seeking NCT05905601 | University of Washington | N/A |
| Not Yet Recruiting | Efficiency of a Composite Personalised Care on Functional Outcome in Early Psychosis NCT05796401 | Centre Hospitalier St Anne | Phase 3 |
| Recruiting | Determining the Role of Social Reward Learning in Social Anhedonia NCT05617898 | University of Alabama at Birmingham | N/A |
| Withdrawn | Cognitive Behavioural Therapy-Informed Groups for Psychosis NCT05584215 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Active Not Recruiting | EPI-MINN: Targeting Cognition and Motivation - National NCT05877716 | University of Minnesota | N/A |
| Recruiting | Effectiveness of Trauma Therapy Using Prolonged Exposure for Patients With PTSD and a Comorbid Psychotic Disor NCT06048172 | Medicalschool Hamburg | N/A |
| Withdrawn | Relationship Between Efficacy of Lumateperone and Brain Glutamate and Dopamine NCT05890768 | University of New Mexico | Phase 4 |
| Completed | Feasibility Trial of a Lifestyle Intervention for CHR-P NCT05532683 | University of California, Los Angeles | N/A |
| Active Not Recruiting | Psychosis TMS Study NCT05857137 | Massachusetts General Hospital | N/A |
| Unknown | Tele-group Cognitive Behavioural Family Intervention (tgCBFI) for People With Schizophrenia and Their Families NCT05808244 | The Hong Kong Polytechnic University | N/A |
| Completed | Motivational Interviewing for Patients With Acute Psychosis NCT05911529 | Psychiatric University Hospital, Zurich | N/A |
| Recruiting | Outcomes From Remediation and Behavioural Intervention Techniques NCT05731414 | University of Toronto | N/A |
| Recruiting | Targeting Emotion Dysregulation to Reduce Suicide in People With Psychosis NCT05440214 | University of Maryland, Baltimore | N/A |
| Unknown | Online Exercise Intervention for Psychosis Patients Receiving Residential Care NCT04631952 | The University of Hong Kong | N/A |
| Recruiting | Piloting of an Intervention to Reduce Problematic Alcohol Use in Early Phase Psychosis Patients NCT05365347 | Nova Scotia Health Authority | N/A |
| Active Not Recruiting | A Combined Aerobic and Resistance Training Program for Adults With Psychotic Disorders NCT05719116 | Solli Distriktspsykiatriske Senter | N/A |
| Completed | Service User and Staff Views on Digital Remote Monitoring for Psychosis NCT05670197 | Manchester Academic Health Science Centre | — |
| Active Not Recruiting | Value of Gym-based Exercise Training for Young Adults Receiving Antipsychotic Medication: The Vega Trial NCT05461885 | Rigshospitalet, Denmark | N/A |
| Recruiting | Multiomic Diagnostics in Youth With Psychosis NCT05457140 | Rady Pediatric Genomics & Systems Medicine Institute | N/A |
| Recruiting | Cognitive Behavior Therapy (CBT) Informed Mobile-Application for First Episode Psychosis NCT05567575 | Pakistan Institute of Living and Learning | N/A |
| Unknown | Bridging Gaps in the Neuroimaging Puzzle: New Ways to Image Brain Anatomy and Function in Health and Disease U NCT05769933 | CSEM Centre Suisse d'Electronique et de Microtechnique SA - Recherche et Developpement | — |
| Completed | Cognitive Behavioral Suicide Prevention for Psychosis: Aim 2 NCT05345184 | University of Michigan | N/A |
| Unknown | Pilot Study to Evaluate the Effectiveness of Online Familiar Metacognitive Training (MCTf) NCT05358457 | Fundació Sant Joan de Déu | N/A |
| Completed | Acceptability and Feasibility of MOL in Acute Inpatient Units NCT05377294 | University of Manchester | N/A |
| Completed | State Representation in Early Psychosis - Project 4 NCT05664594 | University of Minnesota | N/A |
| Completed | Remote State Representation in Early Psychosis NCT05538832 | University of Minnesota | EARLY_Phase 1 |
| Recruiting | Neurobehavioral Mechanisms of Social Isolation and Loneliness in Serious Mental Illness NCT04940663 | Massachusetts General Hospital | N/A |
| Withdrawn | Exercise Target Brain Oscillations in Psychosis NCT05338424 | University of Minnesota | — |
| Completed | CBTpro: Scaling up CBT for Psychosis Using Simulated Patients and Spoken Language Technologies NCT05127837 | University of Washington | N/A |
| Active Not Recruiting | AMP SCZ® Observational Study: PREDICT-DPACC NCT05905003 | Brigham and Women's Hospital | — |
| Enrolling By Invitation | A Comprehensive Third-generation Intervention for People With Psychosis and Post-traumatic Stress Symptoms NCT05619822 | Universidad Complutense de Madrid | N/A |
| Completed | Community Reinforcement and Family Training for Early Psychosis (CRAFT-EP) and Substance Use: A Pilot Study NCT05380583 | Mclean Hospital | N/A |
| Completed | Attachment-focused iMAgery Therapy for PSychosis (A-iMAPS) NCT05042050 | University of Manchester | N/A |
| Recruiting | Examining the Effects of Estradiol on Neural and Molecular Response to Reward NCT05282277 | University of North Carolina, Chapel Hill | Phase 4 |
| Recruiting | E-Detection Tool for Emerging Mental Disorders NCT05127278 | King's College London | — |
| Completed | Imagery Interventions for Auditory Vocal Hallucinations NCT05603260 | Hella Janssen | N/A |
| Completed | Investigation of the Effects of Family-Focused Therapy in the Early Period of Bipolar Disorder and Psychotic D NCT05809193 | Dokuz Eylul University | N/A |
| Completed | Medication Reviews in Severe Mental Illness NCT05243160 | Psychiatric Research Unit, Region Zealand, Denmark | N/A |
| Completed | Psychological Interventions for Complex PTSD And Schizophrenia-Spectrum Disorder: PICASSO Trial NCT05281640 | Edinburgh Napier University | N/A |
| Completed | Community Reinforcement Approach and Family Training for Substance Use in Early Psychosis Intervention NCT05300633 | Centre for Addiction and Mental Health | N/A |
| Recruiting | Neural Basis of Social Cognition Deficits NCT05185128 | Loma Linda University | N/A |
| Active Not Recruiting | Cognitive Remediation for Social Cognition in Schizophrenia and Related Disorders NCT05017532 | Douglas Mental Health University Institute | N/A |
| Completed | State Representation in Early Psychosis NCT05273164 | University of Minnesota | — |
| Active Not Recruiting | CBT-I to Improve Functional Outcomes in Veterans With Psychosis NCT04646200 | VA Office of Research and Development | N/A |
| Unknown | Online Yoga and the Impact on Psychosis NCT05046912 | The Royal Ottawa Mental Health Centre | N/A |
| Completed | Targeting Individual Alpha Frequencies to Enhance Perceptual Timing NCT04856657 | University of Minnesota | — |
| Completed | Improving Hallucinations by Targeting the rSTS With tES NCT05165654 | Beth Israel Deaconess Medical Center | N/A |
| Recruiting | Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk NCT05131035 | Northwell Health | N/A |
| Completed | Cultural Adaptation of Group CBT Psychosis Manual and Establishing Its Efficacy in Pakistan NCT07005388 | Punjab Institute of Mental Health | N/A |
| Completed | Effect and Cost-effectiveness of the Everyday Life Rehabilitation Intervention NCT05056415 | Umeå University | N/A |
| Unknown | Application of UP for Transdiagnostic Treatment of Emotional Disorders for UHR for Psychosis Patients NCT04929938 | Fundació Sant Joan de Déu | N/A |
| Completed | Cognitive Behavioral Suicide Prevention for Psychosis: Aim 1 NCT04689867 | University of Michigan | N/A |
| Unknown | The Effect of Psycho-education on Clinical Outcomes Among Patients With a First Episode Psychosis in Central U NCT04602585 | Makerere University | N/A |
| Active Not Recruiting | EPI-MINN: Targeting Cognition and Motivation NCT05112432 | University of Minnesota | N/A |
| Completed | Effects of Music Beat on Motor Function in Individuals At Risk for Psychotic Onset and Schizophrenia Patients NCT04929795 | Dr WANG Shumei | N/A |
| Recruiting | Effectiveness of the Combination of Water Aerobics and Metacognitive Training NCT05455593 | Fundació Sant Joan de Déu | N/A |
| Recruiting | Toward a Computationally-Informed, Personalized Treatment for Hallucinations NCT04366518 | Yale University | EARLY_Phase 1 |
| Unknown | Virtual Reality Avatar Therapy for People Hearing Voices NCT04099940 | Psychiatric University Hospital, Zurich | N/A |
| Completed | Social Skills and Emotion Regulation Training "SSERT" for Trauma in Psychosis NCT05100875 | Douglas Mental Health University Institute | N/A |
| Recruiting | Add-on MEmaNtine to Dopamine Modulation to Improve Negative Symptoms at First Psychosis NCT04789915 | Bjorn H. Ebdrup | Phase 1 |
| Unknown | Source-monitoring & Psychosis NCT04236531 | Hôpital le Vinatier | N/A |
| Unknown | Implementation of Digital CBT for Insomnia in First Episode Psychosis NCT05050201 | NHS Greater Glasgow and Clyde | N/A |
| Unknown | On Track Chile For First Episode Psychosis NCT04247711 | University of Chile | N/A |
| Unknown | Ketogenic Diet for Psychotic Disorders NCT03873922 | Kuopio University Hospital | N/A |
| Terminated | Young People and Illness Management and Recovery (IMR) NCT04778085 | University Hospital, Akershus | — |
| Recruiting | Biomarkers in Clozapine-responding Schizophrenia NCT05316883 | Jimmi Nielsen | Phase 4 |
| Recruiting | Neuroimmunology Registry and Biobank NCT06958341 | Charite University, Berlin, Germany | — |
| Unknown | Effectiveness of Trauma Therapy in Patients With PTSD and Comorbid Psychotic Disorder NCT04911010 | University of Hamburg-Eppendorf | N/A |
| Active Not Recruiting | Family-Focused Therapy for Individuals at High Clinical Risk for Psychosis: A Confirmatory Efficacy Trial NCT04338152 | University of California, Los Angeles | N/A |
| Withdrawn | Group Cognitive Behavioural Family Intervention (CBFI) for People With Schizophrenia and Their Families NCT04065360 | Hospital Authority, Hong Kong | N/A |
| Completed | USS Training to Improve Social Function in People With Psychosis NCT04557124 | VA Office of Research and Development | N/A |
| Unknown | Study to Compare Clozapine vs Treatment as Usual in People With Intellectual Disability & Treatment-resistant NCT04529226 | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | Phase 2 |
| Completed | Developing Clinical Tools to Communicate Genetic Risk for Individuals Who Are Clinical High Risk for Psychosis NCT04325568 | New York University | Phase 1 |
| Completed | CBT to Reduce Insomnia and Improve Social Recovery in Early Psychosis NCT04180709 | University of Cambridge | N/A |
| Unknown | Be Outspoken and Overcome Stigmatizing Thoughts (BOOST) Group for Early Psychosis NCT05571228 | Queen's University | N/A |
| Completed | RELATE - Efficacy and Feasibility of a Cognitive Behavioural Module for Distressing Auditory Verbal Hallucinat NCT04578314 | University of Hamburg-Eppendorf | N/A |
| Completed | Families With Substance Use and Psychosis: A Pilot Study NCT04284813 | Mclean Hospital | N/A |
| Terminated | FAAH Availability in Psychiatric Disorders: A PET Study NCT04404712 | Yale University | EARLY_Phase 1 |
| Completed | ED to EPI: Using SMS to Improve the Transition From the Emergency Department to Early Psychosis Intervention NCT04298450 | Centre for Addiction and Mental Health | N/A |
| Unknown | Effects of Rhythmic Auditory Stimulation on Movements in Individuals at Risk for Psychotic Onset and Schizophr NCT04553835 | Dr WANG Shumei | N/A |
| Unknown | Clozapine Versus Olanzapine as Treatment for Comorbid Psychotic Disorder and Substance Use Disorder NCT03857581 | Augusta University | Phase 4 |
| Completed | Psychoeducative Treatment of FEP With Mobile Training. ThinkApp NCT03161249 | International University of La Rioja | N/A |
| Completed | Pilot Study of Motivational Interviewing for Loved Ones NCT04010747 | Boston Medical Center | N/A |
| Recruiting | Goals in Focus: CBT for Motivational Negative Symptoms of Psychosis NCT05252039 | University of Hamburg-Eppendorf | N/A |
| Completed | Multi-modal Assessment of Gamma-aminobutyric Acid (GABA) Function in Psychosis NCT04004416 | University of Michigan | Phase 4 |
| Completed | Early Psychosis Intervention - Spreading Evidence-based Treatment NCT03919760 | Centre for Addiction and Mental Health | N/A |
| Unknown | Shared Decision Making in Psychiatric Inpatient Care NCT04175366 | Umeå University | N/A |
| Recruiting | Normobaric Oxygen Therapy for Individuals With First-Episode Psychosis NCT04368039 | Nicholas Breitborde | N/A |
| Recruiting | Dundrum Forensic Redevelopment Evaluation Study: D-FOREST Study. NCT05074732 | Health Service Executive, Ireland | — |
| Recruiting | Genetic Counselling in the Prevention of Mental Health Consequences of Cannabis Use NCT03601026 | Nova Scotia Health Authority | N/A |
| Unknown | VR Therapy for Psychosis Negative Symptoms (V-NeST) NCT03995420 | Institute of Psychiatry, London | N/A |
| Unknown | The Clinical and Socio-demographic Characteristics of Young People Aged 12 to 25 Consulting on Ambulatory Stru NCT04365621 | Januel | N/A |
| Completed | Extreme Challenges - Psychopathology & Treatment Experiences Among Severly Selfharming Inpatients in Norway NCT03768674 | Oslo University Hospital | — |
| Completed | Feasibility of an Early Detection Program for Early Psychosis on a College Campus NCT03983421 | University of New Mexico | — |
| Completed | Effects of Intranasal Insulin on Neuroimaging Markers and Cognition in Patients With Psychotic Disorders NCT03943537 | Mclean Hospital | Phase 2 |
| Unknown | Mindfulness Intervention and Relapse in Psychosis NCT04060498 | The University of Hong Kong | N/A |
| Unknown | Cognitive Remediation and Social Recovery in Early Psychosis NCT04273685 | National University of Ireland, Galway, Ireland | N/A |
| Completed | Improving Access to Early Psychosis Coordinated Specialty Care NCT04277585 | University of North Carolina, Chapel Hill | N/A |
| Terminated | Mechanisms of Cognitive Change NCT04103775 | Colorado State University | N/A |
| Completed | Psychological Therapy for Dissociation, Trauma and Voices: A Single Case Experimental Design NCT04127526 | NHS Greater Glasgow and Clyde | N/A |
| Unknown | ReMindCare App for Patients From First Episode of Psychosis Unit. NCT03807388 | Instituto de Investigacion Sanitaria INCLIVA | N/A |
| Withdrawn | HOPE TEAM - Clinical High Risk Group CBSST NCT03738046 | University of Pittsburgh | N/A |
| Completed | Virtual Reality Assisted CBT for Social Difficulties: a Feasibility Study in Early Intervention for Psychosis NCT04310475 | King's College London | N/A |
| Unknown | Effects of Transcranial Direct Current Stimulation (tDCS) on Motor Function in Schizophrenia Patients and Indi NCT04086160 | Dr WANG Shumei | N/A |
| Completed | Walking for Health: an Intervention to Increase Physical Activity and Reduce Sedentary Behaviour in People Wit NCT04134871 | University of Ulster | N/A |
| Unknown | Method of Level (MOL) Therapy for Psychosis NCT04038112 | University of Manchester | N/A |
| Completed | Hippocampal Memory Circuits in Delusions NCT03822910 | NYU Langone Health | — |
| Unknown | Perinatal Mental Health Care in Switzerland NCT04185896 | Bern University of Applied Sciences | — |
| Completed | Transcranial Direct Current Stimulation and Cognitive Remediation Therapy for Psychosis NCT02085421 | University of Minnesota | N/A |
| Completed | Museum-based Group Art Therapy in Mental Health Recovery NCT03985904 | Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud | N/A |
| Completed | Action-based Cognitive Remediation for First Episode Psychosis NCT03814122 | University of Manitoba | N/A |
| Withdrawn | Enhancement of Treatment of Delusions in Schizophrenia Through Neuromodulation NCT03062553 | University of British Columbia | N/A |
| Completed | Melatonin Effects on Sleep and Circadian Rhythm in Youth and Young Adults With At-risk Symptoms NCT03826563 | Children's Hospital of Philadelphia | N/A |
| Completed | Effects of Aerobic Exercise, Cognitive Remediation and Combined Intervention in Schizophrenia NCT06810362 | IRCCS San Raffaele | N/A |
| Unknown | Body-Mind-Spirit Intervention for Women With Early Psychosis NCT03751852 | The University of Hong Kong | N/A |
| Completed | OnTrack>An Online Role-Playing Game for Young People With First Episode Psychosis NCT03390491 | Center for Social Innovation, Massachusetts | N/A |
| Completed | CSC OnDemand: An Innovative Online Learning Platform for Implementing Coordinated Specialty Care NCT03465371 | Center for Social Innovation, Massachusetts | N/A |
| Unknown | Can Imagination Change Upsetting Memories of Trauma? NCT03607630 | King's College London | Phase 1 / Phase 2 |
| Unknown | From Prevention to Community Integration: IPCST for Severe Mental Illness in Chinese Communities (Hong Kong an NCT03565055 | The Hong Kong Polytechnic University | N/A |
| Completed | Technology-Enabled Collaborative Care for Youth NCT03610087 | Centre for Addiction and Mental Health | N/A |
| Completed | Piloting MOL Intervention for Neuroleptic Decision Making NCT03537040 | University of Manchester | N/A |
| Recruiting | Semantic and Syntactic Computerized Analysis of Free Speech NCT03525054 | University Hospital, Brest | — |
| Active Not Recruiting | Trajectories of Treatment Response as Window Into the Heterogeneity of Psychosis: a Longitudinal Multimodal Im NCT03442101 | University of Alabama at Birmingham | — |
| Completed | Improving Psychological Therapy for Psychosis: A Case Series NCT03920384 | University of Edinburgh | N/A |
| Completed | CBT-I for Psychosis: Guidelines, Preliminary Efficacy, and Functional Outcomes NCT02535923 | VA Office of Research and Development | N/A |
| Unknown | Early Detection of Respiratory Disorders in Psychosis NCT03476473 | Fundación Marques de Valdecilla | — |
| Unknown | Searching for Early Biomarkers of Long-term Hepatic, Metabolic and Endothelial Dysfunction in Non-affective Ps NCT03481465 | Fundación Marques de Valdecilla | — |
| Terminated | The Norwegian Prednisolone in Early Psychosis Study NCT03340909 | Haukeland University Hospital | Phase 2 |
| Completed | Just Do You Program for Young Adults With Serious Mental IIlness NCT03423212 | New York University | N/A |
| Unknown | Influence of Amphetamine-induced Sensitization on Dopamine Synthesis and Release NCT03223844 | Medical University of Vienna | N/A |
| Completed | The Evaluation of the Use of a New Physical Health Plan NCT03178279 | King's College London | N/A |
| Unknown | Neuroinflammation Markers in Subjects With Psychotic Symptoms NCT05815225 | Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud | — |
| Recruiting | IVIG and Rituximab in Antibody-associated Psychosis - SINAPPS2 NCT03194815 | University of Cambridge | Phase 2 |
| Completed | Impact of Video Presentations on Medical Students' Attitudes Toward Mental Illness NCT03231761 | George Washington University | N/A |
| Completed | Levetiracetam in Early Psychosis NCT03129360 | NYU Langone Health | Phase 2 |
| Unknown | Guided Dose Reduction of Antipsychotic in Patients With Psychosis in Remitted States NCT03248180 | National Taiwan University Hospital | — |
| Completed | Aspirin in Young Psychotic Patients NCT02685748 | Clinic for Psychiatric Disorders, Dr Laza Lazarevic | Phase 2 / Phase 3 |
| Completed | Is Cognitive Training Neuroprotective in Early Psychosis? NCT03049800 | University of Minnesota | — |
| Completed | Minnesota Community-Based Cognitive Training in Early Psychosis NCT03079024 | University of Minnesota | N/A |
| Completed | The Relationship Between Autobiographical Memory and Motivation NCT03677635 | King's College London | N/A |
| Completed | Testing the Effectiveness of The Welcome Basket Intervention NCT02946255 | Centre for Addiction and Mental Health | N/A |
| Completed | Cognitive AppRoaches to coMbatting Suicidality NCT03114917 | University of Manchester | N/A |
| Terminated | A Study of MP-101 in Dementia-Related Psychosis and/or Agitation and Aggression NCT03044249 | Mediti Pharma Inc. | Phase 2 |
| Completed | Mobile Enhancement of Motivation in Schizophrenia NCT03059771 | Indiana University | N/A |
| Withdrawn | Thermoregulation Among Individuals With First-episode Psychosis NCT04369677 | Nicholas Breitborde | — |
| Completed | Mindfulness, Group Therapy and Psychosis; Training Decreases Anxiety and Depression NCT04711460 | University of Minnesota | — |
| Terminated | rTMS Treatment for Cannabis Use Disorders in Psychosis NCT03069612 | Centre for Addiction and Mental Health | N/A |
| Completed | CSC OnDemand: An Innovative Online Learning Platform for Implementing Coordinated Specialty Care NCT02933567 | Center for Social Innovation, Massachusetts | N/A |
| Completed | Prefrontal Cortical Engagement Through Non-Invasive Brain Stimulation in Schizophrenia NCT02975973 | Baylor College of Medicine | N/A |
| Completed | RCT Examining the Effectiveness of Digital Picture Frame Use in Inpatient Setting NCT02950571 | Centre for Addiction and Mental Health | N/A |
| Completed | Cognitive Training Delivered Remotely to Individuals With Psychosis (ROAM) NCT02782442 | University of Minnesota | N/A |
| Completed | COllaborative Shared Care to IMprove Psychosis Outcome NCT02895269 | University of Ibadan | N/A |
| Terminated | Non-Invasive Direct Current Stimulation for Cognition in Schizophrenia NCT02739347 | Baylor College of Medicine | N/A |
| Unknown | Efficacy of Social Cognitive Training (SCT) in Recent-onset Psychosis NCT03962426 | Ludwig-Maximilians - University of Munich | N/A |
| Terminated | Cognitive Remediation in Youth at Risk of Serious Mental Illness NCT02582528 | University of Calgary | N/A |
| Completed | Participatory Messaging in the UCLA Psychiatry Partial Hospitalization and Intensive Outpatient Programs NCT02708940 | University of California, Los Angeles | N/A |
| Completed | Improving Adherence to Cognitive Rehabilitation NCT02481713 | VA Office of Research and Development | N/A |
| Completed | Minocycline and/or Omega-3 Fatty Acids Added to Treatment as Usual for At Risk Mental States NCT02569307 | Pakistan Institute of Living and Learning | Phase 2 |
| Completed | Compassion Focused Therapy for Distressing Experiences NCT02733575 | King's College London | N/A |
| Completed | Cbt for Psychosis and Affect on Psychosis Symptoms NCT02653729 | Aisha Andleeb | Phase 2 |
| Unknown | Understanding and Helping Families: Parents With Psychosis NCT02622048 | University of Manchester | N/A |
| Completed | Computer-Aided Learning for Managing Stress NCT02531243 | Beth Israel Deaconess Medical Center | N/A |
| Completed | Smartphone Applications Youth With Early Psychosis in Community Outpatient Settings NCT03286595 | University of California, Davis | N/A |
| Completed | Study of Immunotherapy in Autoantibody Positive Psychosis NCT02449746 | University of Cambridge | N/A |
| Completed | Effect of N-acetylcysteine on Brain Glutamate NCT02483130 | King's College London | — |
| Completed | OnTrack>An Online Role-Playing Game: A Small Business Innovation Research (SBIR) Grant NCT02415764 | Center for Social Innovation, Massachusetts | Phase 1 |
| Unknown | The Music Study in Refractory Psychosis NCT02431949 | University of British Columbia | — |
| Completed | Feasibility and Acceptability of a Smartphone App to Assess Early Warning Signs of Psychosis Relapse NCT03558529 | Manchester Academic Health Science Centre | — |
| Completed | A Study of the Effectiveness of Cognitive Adaptation Training in Early Intervention for Psychosis NCT02430935 | Centre for Addiction and Mental Health | N/A |
| Completed | Occupational Recovery After First Episode Psychosis NCT03317132 | Fraser Health | N/A |
| Completed | Researching the Effectiveness of Acceptance-Based Coping During Hospitalization NCT02336581 | Butler Hospital | N/A |
| Completed | Adaptation of Cognitive Enhancement Therapy for Persons at Clinical High Risk for Psychosis NCT02459210 | Beth Israel Deaconess Medical Center | N/A |
| Unknown | Neurocognitive Effectiveness in Treatment of First-episode Non-affective Psychosis: 3-years Follow-up NCT03883204 | Fundación Marques de Valdecilla | Phase 4 |
| Completed | Using Mobile Technology to Enhance Early Psychosis Treatment Delivery NCT03303456 | University of California, Davis | N/A |
| Unknown | Compensatory Cognitive Training in Clinical High Risk Latino Youth NCT02245607 | University of California, San Diego | N/A |
| Completed | Manualized Group Cognitive-behavioral Therapy for Social Anxiety in First Episode Psychosis NCT02294409 | Douglas Mental Health University Institute | N/A |
| Unknown | Mindfulness RCT for Early Psychosis NCT02244970 | The University of Hong Kong | N/A |
| Unknown | The BC Psychosis Program Biobank and Database for Genetic Polymorphisms and Their Associations With Psychosis NCT02322918 | University of British Columbia | — |
| Completed | Curcumin as a Novel Treatment to Improve Cognitive Dysfunction in Schizophrenia NCT02104752 | VA Greater Los Angeles Healthcare System | Phase 1 / Phase 2 |
| Completed | Treatment of Psychosis and Agitation in Alzheimer's Disease NCT02129348 | New York State Psychiatric Institute | Phase 2 |
| Unknown | Effectiveness of Second Generation Antipsychotics in First Episode Psychosis Patients: 3-year Follow-up NCT03090503 | Fundación Marques de Valdecilla | Phase 4 |
| Completed | Person-Centered Psychosis Care: An Educational Intervention NCT03182283 | Göteborg University | N/A |
| Completed | STEP-ED: Reducing Duration of Untreated Psychosis and Its Impact in the U.S. NCT02069925 | Yale University | N/A |
| Active Not Recruiting | Probing the Cannabinoid System in Individuals With a Family History of Psychosis NCT02102113 | Yale University | EARLY_Phase 1 |
| Completed | Glutamate, Brain Connectivity and Duration of Untreated Psychosis NCT02034253 | University of Alabama at Birmingham | — |
| Completed | Community-Based Cognitive Training in Early Schizophrenia NCT01973270 | University of California, San Francisco | N/A |
| Completed | Psychosis-Associated Neuroinflammation in Schizophrenia NCT02009826 | Universiteit Antwerpen | — |
| Completed | Pediatric Bipolar Registry NCT02360267 | The University of Texas Health Science Center, Houston | — |
| Completed | Cognitive Remediation for First Episode of Psychosis Patients NCT01967420 | University of Manchester | N/A |
| Terminated | Brief Motivational Enhancement Therapy for Concurrent Disorders NCT01924039 | Centre for Addiction and Mental Health | N/A |
| Unknown | Cognitive Remediation in Schizophrenia NCT01903707 | University of Dublin, Trinity College | N/A |
| Completed | Effect Evaluation of Individual Placement and Support (IPS) NCT01964092 | NORCE Norwegian Research Centre AS | N/A |
| Unknown | Economic and Clinical Outcomes of Attendance in Psychosis Services Using SMS. NCT01793220 | King's College London | N/A |
| Completed | Intervention Module AGES NCT02101372 | Celso Arango | N/A |
| Terminated | Contrasting Group Therapy Methods for Psychosis NCT01764568 | University of British Columbia | N/A |
| Completed | Prevalence of Clinical and Laboratory Markers of Hypofibrinolysis in Psychotic Patients NCT01487291 | Universidade Federal do Rio de Janeiro | — |
| Completed | The Family Cognitive Adaptation Training Manual: A Test of Effectiveness NCT01768000 | Centre for Addiction and Mental Health | N/A |
| Unknown | The Pharmaco-genetic and Brain Mechanisms Associated With Cannabis- Induced Psychosis NCT01565174 | Hadassah Medical Organization | — |
| Completed | Effectiveness of Meta-Cognitive Training (EMC) in People With Psychosis of Brief Evolution. NCT02340559 | Fundació Sant Joan de Déu | N/A |
| Completed | Social Cognitive Training for Psychosis: Treatment Development NCT01579422 | Yale University | Phase 1 |
| Completed | Culturally Adapted Cognitive Behavior Therapy for Psychosis in Pakistan NCT02202694 | Pakistan Institute of Living and Learning | N/A |
| Completed | Culturally Adapted Family Intervention For Psychosis NCT02167347 | Pakistan Institute of Living and Learning | N/A |
| Completed | Neuroplasticity-oriented Cognitive Intervention in Early Onset and First Admission Schizophrenia NCT01781364 | University of Konstanz | N/A |
| Completed | Effectiveness of Cognitive Remediation in a Supported Education Setting NCT01492439 | Centre for Addiction and Mental Health | N/A |
| Completed | Brain Connectivity in Neurodevelopmental Disorders in Response to Treatment NCT01364818 | University of North Carolina, Chapel Hill | — |
| Completed | NAPLS Omega-3 Fatty Acid Versus Placebo Study NCT01429454 | University of California, San Diego | Phase 1 |
| Completed | Peer Support for Severe Mental Disorders NCT02276469 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Completed | Multi-site Communication Deficits in Schizophrenia NCT01317121 | Universitätsklinikum Hamburg-Eppendorf | — |
| Completed | A Novel Person-Centered Treatment Component for Substance Use Treatment NCT02005367 | Hampton VA Medical Center | N/A |
| Completed | Treatment to Enhance Cognition in Bipolar Disorder NCT01470781 | Mclean Hospital | N/A |
| Completed | To Rescue Cognition With Valaciclovir NCT01364792 | University Medical Center Groningen | Phase 2 |
| Completed | Social Cognition Intervention NCT01267019 | VA Office of Research and Development | N/A |
| Completed | Cognitive Behavioral Therapy for Patients With an Early Psychosis NCT01511406 | Oslo University Hospital | Phase 2 |
| Unknown | Clinical Intervention Psychosis and Addiction NCT01411566 | University of Cologne | EARLY_Phase 1 |
| Completed | e-Learning & Development of an Evidence-based Psychoeducational Programme for First Episode Psychosis NCT01783457 | Basque Health Service | N/A |
| Completed | Multi-disciplinary Treatment for Patients Experiencing First Episode of Psychosis NCT01216891 | Research Foundation for Mental Hygiene, Inc. | N/A |
| Completed | Effects of Aripiprazole and Haloperidol on Mesolimbic System Functioning NCT01161277 | Oslo University Hospital | Phase 4 |
| Terminated | Metyrosine (Demser®) for the Treatment of Psychotic Disorders in Patients With Velocardiofacial Syndrome NCT01127503 | Bausch Health Americas, Inc. | Phase 2 |
| Completed | A Usability Study of a Smoking Cessation Decision Aid in People With a Recent First Episode of Psychosis NCT01399112 | Northwell Health | N/A |
| Completed | Tolerance and Effect of Antipsychotics in Children and Adolescents With Psychosis NCT01119014 | Anne Katrine Pagsberg | Phase 4 |
| Completed | A Large Pragmatic Cluster Randomized Controlled Trial of a Multi-element Psychosocial Intervention for Early P NCT01436331 | Universita di Verona | N/A |
| Completed | Treatment of Alcohol Dependence and Comorbid Bipolar Disorder NCT01015586 | Medical University of South Carolina | Phase 4 |
| Completed | Prevention Trial of Family Focused Treatment in Youth at Risk for Psychosis NCT01907282 | University of California, Los Angeles | N/A |
| Completed | Optimizing Cognitive Remediation Outcomes in Schizophrenia NCT02105779 | University of California, San Francisco | N/A |
| Completed | Paternal Psychosis After Baby Born NCT01011088 | Nanjing Medical University | — |
| Completed | Intensive Computerized Brain Training (ICBT) in Youth With Early Onset Psychosis (EOP) NCT01027962 | University of North Carolina, Chapel Hill | N/A |