NCT07005388

Cultural Adaptation of Group CBT Psychosis Manual and Establishing Its Efficacy in Pakistan

CULTURAL ADAPTATION OF GROUP CBT PSYCHOSIS MANUAL AND ESTABLISHING ITS EFFICACY IN PAKISTAN

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Punjab Institute of Mental Health · Other Government
• Sex: All
• Age: 65 Years
• Healthy volunteers: Not accepted

Summary

A study aimed to culturally adapt group Cognitive Behavioral Therapy for psychosis (CBTp) for Pakistani patients with schizophrenia. Fifty inpatients from PIMH were randomly assigned to experimental (N=25) and control (N=25) groups. Both groups showed significant improvement in symptoms post-intervention (p\<0.05). This suggests that culturally adapted group CBTp is effective for schizophrenia patients in hospital settings, addressing the scarcity of CBT-trained therapists in government hospitals in Pakistan.

Detailed description

A clinical trial was conducted aiming to culturally adapt and pilot test a group Cognitive Behavioral Therapy for psychosis (CBTp) protocol for Pakistani patients diagnosed with schizophrenia spectrum disorder. This research was particularly significant given the prevalence of psychosis in Pakistan and the scarcity of trained therapists, especially in government hospitals. Methodology: Participant Selection: Purposive sampling was utilized to select participants from the Psychiatric Institute of Mental Health (PIMH) who were diagnosed with schizophrenia spectrum disorder and were inpatients receiving medication. Sample Size: A total sample of N=50 was obtained, with participants randomly assigned to either the experimental (N=25) or control group (N=25). Assessment Measures: Various assessment measures were employed to evaluate the efficacy of the intervention, including the Positive and Negative Syndrome Scale of Schizophrenia (PANSS), Rosenberg's Self Esteem Scale, Insight Scale, Brief COPE, Perceived Stress Scale, and The Psychotic Symptom Rating Scales (PSYRATS). Intervention: The experimental group received manualized group CBT intervention consisting of 24 sessions over a duration of 3 months. The intervention was culturally adapted to suit the needs and context of Pakistani patients. Importantly, there were no dropouts from either group during the intervention period. Statistical Analysis: An analysis of covariance (ANCOVA) was conducted to compare pre- and post-intervention ratings between the experimental and control groups.

Conditions

• Psychotic Disorders
• Psychosis
• Schizophrenia and Related Disorders

Interventions

Type	Name	Description
BEHAVIORAL	Cognitive behavioral therapy for psychosis	Cognitive behavioral therapy for psychosis is a group protocol design specially for psychotic patients to treat their positive and negative symptoms

Timeline

• Start date: 2021-10-04
• Primary completion: 2023-05-03
• Completion: 2023-05-03
• First posted: 2025-06-05
• Last updated: 2025-06-05

Locations

1 site across 1 country: Pakistan