Trials / Active Not Recruiting
Active Not RecruitingNCT05857137
Psychosis TMS Study
Investigational TMS Study of Cognitive Impairment in Early Psychosis
- Status
- Active Not Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- Sponsor
- Massachusetts General Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 35 Years
- Healthy volunteers
- Not accepted
Summary
The main goal of this study is to investigate the neural mechanisms of working memory function in patients with early psychosis using Transcranial Magnetic Stimulation (TMS) in conjunction with functional MRI. TMS is a noninvasive method used to modulate brain activity via changing magnetic fields applied over the surface of the scalp.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | Active TMS | Continuous theta burst stimulation (cTBS) will be administered over the left inferior parietal lobule for approximately 3 minutes at 120% of the resting motor threshold. |
| DEVICE | Placebo TMS | Placebo TMS will be applied over the left inferior parietal lobule for approximately 3 minutes. |
Timeline
- Start date
- 2023-04-04
- Primary completion
- 2026-04-15
- Completion
- 2026-07-30
- First posted
- 2023-05-12
- Last updated
- 2026-02-10
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated device study
Source: ClinicalTrials.gov record NCT05857137. Inclusion in this directory is not an endorsement.