| Not Yet Recruiting | TH104 for the Treatment of Pruritus in Primary Biliary Cholangitis NCT06733519 | Tharimmune Inc | Phase 2 |
| Recruiting | Safety and Tolerability of Difelikefalin in Adolescents on Haemodialysis With Moderate-to-Severe Pruritus NCT06593392 | Vifor Fresenius Medical Care Renal Pharma | Phase 2 |
| Not Yet Recruiting | Assessing the Efficacy and Safety of Photobiomodulation for the Treatment of Pruritus NCT07450716 | Massachusetts General Hospital | EARLY_Phase 1 |
| Recruiting | VR-PMR for Post-Burn Symptoms NCT07317271 | Johns Hopkins University | N/A |
| Not Yet Recruiting | Methotrexate Versus Apremilast for Pruritus in Psoriasis NCT07432386 | Zarmeen Khawar | Phase 4 |
| Recruiting | Drug-induced Liver Injury: Itching Study NCT06446609 | University of Nottingham | — |
| Recruiting | Cervical Traction to Reduce Gabaergic Medication Use for Neuropathic Itch NCT06751056 | Mayo Clinic | N/A |
| Not Yet Recruiting | Aprepitant in the Management of Immune Checkpoint Inhibitors Pruritus in Solid Cancer Patients NCT06931119 | Rabin Medical Center | Phase 1 |
| Not Yet Recruiting | A Clinical Study to Assess the Safety and Effectiveness of Utixira Lotion and Utixira Tablet in Healthy Adult NCT06924840 | SAVA Healthcare Limited | N/A |
| Not Yet Recruiting | Efficacy and Tolerance of Cannabidiol in Patients with Severe Pruritus: a Multicenter, Double-blind, Randomize NCT06435299 | University Hospital, Brest | Phase 3 |
| Recruiting | Evaluation of the Efficacy and Tolerance of the Medical Device RL3020-DP0364 in Adult Population With Stable M NCT06800755 | Pierre Fabre Dermo Cosmetique | N/A |
| Recruiting | Reducing Itch With Hypnosis and Virtual Reality NCT06787794 | Universiteit Leiden | N/A |
| Completed | Effect of Topically Applied Olive Oil on Pruritus in Hemodialysis Patients: Pretest-posttest Model With Contro NCT06737484 | Inonu University | N/A |
| Unknown | A Study of HSK21542 in a Peritoneal Dialysis Pruritus Population. NCT06290375 | Xizang Haisco Pharmaceutical Co., Ltd | Phase 2 |
| Completed | Effect of Lidocaine Infusion on Neuraxial Opioid-induced Pruritus After Cesarean Section NCT06225323 | Aswan University | N/A |
| Unknown | The Effect of Cold Gel Pack Application on Itching in Burn Patients in the Maturation Stage NCT06334679 | Marmara University | N/A |
| Recruiting | The Efficacy of 3% Kanuka Oil Versus 1% Hydrocortisone Cream in Patients With Atopic Dermatitis NCT06488742 | Nexgen Dermatologics, Inc. | N/A |
| Recruiting | Swiss Itch Registry NCT06120907 | University Hospital, Basel, Switzerland | — |
| Terminated | Study to Evaluate the Efficacy and Safety of Oral Difelikefalin for Moderate to Severe Pruritus in Subjects Wi NCT05978063 | Cara Therapeutics, Inc. | Phase 2 / Phase 3 |
| Completed | Bioequivalence Study of Nalfurafine Hydrochloride Orally Disintegrating Tablets on Fasting and Fed in Humans NCT07478133 | Shandong New Time Pharmaceutical Co., LTD | N/A |
| Completed | A Study to Evaluate the Anti-pruritic Effectiveness of ASN008 in Adults With Mild to Moderate Atopic Dermatiti NCT05870865 | Formation Bio, Inc. | Phase 2 |
| Not Yet Recruiting | Establishment of a Patient Library in Patients With Pruritus Sine Materia NCT05678309 | University Hospital, Brest | — |
| Unknown | Efficacy of CeraVe® Moisturizing Cream on Skin Pruritus in Elderly Patients NCT05779150 | Shanghai Zhongshan Hospital | N/A |
| Withdrawn | Treatment of Chronic Itch in Atopic Dermatitis With Opioid Antagonist Naltrexone NCT04325802 | University of Minnesota | Phase 2 |
| Completed | Does Indoxyl Sulfate Have a Role in Uremic Pruritus? NCT05634083 | Benha University | N/A |
| Recruiting | Meditation in Inflammatory Dermatosis NCT05500794 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Study to Evaluate EP547 in Subjects With Cholestatic Pruritus Due to Primary Biliary Cholangitis or Primary Sc NCT05525520 | Escient Pharmaceuticals, Inc | Phase 2 |
| Unknown | The Role of Skin Microbiota in Hepatic or Renal Pruritus NCT05604469 | Zagazig University | — |
| Terminated | CR845-310302: A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease NCT05356403 | Cara Therapeutics, Inc. | Phase 3 |
| Terminated | Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid NCT05387707 | Cara Therapeutics, Inc. | Phase 3 |
| Completed | Food Effect Study of Linerixibat Tablets in Healthy Adult Participants NCT05435170 | GlaxoSmithKline | Phase 1 |
| Completed | DIalysis Symptom COntrol-Pruritus Outcome Trial NCT05180968 | University of Manitoba | Phase 3 |
| Completed | Phase I Study of Linerixibat in Adults With Moderate Hepatic Impairment and Healthy Controls NCT05393076 | GlaxoSmithKline | Phase 1 |
| Completed | Defining N-Acetyl Cysteine as a Treatment for Inhibiting Prurogenic Stimuli NCT05287724 | Wright State University | EARLY_Phase 1 |
| Completed | A Clinical Trial Evaluating the Efficacy and Safety of HSK21542 in Patients with Chronic Kidney Disease-Associ NCT05135390 | Haisco Pharmaceutical Group Co., Ltd. | Phase 3 |
| Terminated | A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With NCT05342623 | Cara Therapeutics, Inc. | Phase 3 |
| Completed | Gabapentin Versus Loratadine in Uremic Pruritus NCT05750875 | King Edward Medical University | Phase 4 |
| Completed | Bioavailability and Tolerability of Fexofenadine Hydrochloride Topical Lotion 1% NCT05461456 | OrchestratePharma GmbH | Phase 1 |
| Recruiting | Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of NCT05263206 | Sanofi | Phase 3 |
| Completed | Linerixibat and Obeticholic Acid Drug Interaction Study in Healthy Adult Participants NCT05133830 | GlaxoSmithKline | Phase 1 |
| Completed | A Clinical Trial Evaluating the Efficacy, Safety, and Pharmacokinetics of HSK21542 Injection in Liver Disease NCT04999787 | Haisco Pharmaceutical Group Co., Ltd. | Phase 2 |
| Completed | Efficacy of Abrocitinib for Reducing Pruritus in Adults With Prurigo Nodularis and Chronic Pruritus of Unknown NCT05038982 | Johns Hopkins University | Phase 2 |
| Completed | Global Linerixibat Itch Study of Efficacy and Safety in Primary Biliary Cholangitis (PBC) (GLISTEN) NCT04950127 | GlaxoSmithKline | Phase 3 |
| Terminated | Psychogenic and Neurogenic Components in Patients With Psychogenic or Neuropathic Pruritus NCT05024851 | University Hospital, Brest | — |
| Completed | Treatment of Pruritus With Intramuscular Promethazine NCT04805073 | University of Florida | Phase 4 |
| Completed | The Efficacy of VR and AR on Pruritus NCT04289038 | Hacettepe University | N/A |
| Completed | Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Sub NCT04706975 | Cara Therapeutics, Inc. | Phase 2 |
| Completed | Blue Light in the Treatment of Inflammatory Skin Diseases NCT06516783 | Medical University of Lodz | N/A |
| Unknown | Enhanced Recovery After Cesarean Section With Low Dose Intrathecal Morphine. NCT04618146 | Minia University | N/A |
| Completed | Postoperative Pain After Caesarian Section NCT05659823 | Conrad Arnfinn Bjørshol | Phase 4 |
| Unknown | Adding Nalbuphine for Control of Intrathecal Morphine Pruritus NCT04589429 | Minia University | Phase 2 |
| Withdrawn | Treatment of Chronic Itch in Atopic Dermatitis With Topical Naltrexone NCT04154033 | University of Minnesota | Phase 2 |
| Completed | Evaluate the Safety, Tolerability, and PK of EP547 in Healthy Subjects and Subjects With Cholestatic or Uremic NCT04510090 | Escient Pharmaceuticals, Inc | Phase 1 |
| Completed | The Effect of Propofol on Dexamethasone-induced Perineal Pruritus NCT04337073 | Yangzhou University | EARLY_Phase 1 |
| Completed | Dupilumab for the Treatment of Moderate to Severe Chronic Hepatic Pruritus NCT04256759 | Mayo Clinic | Phase 2 |
| Completed | Prevalence of a Localized or Diffuse Pruritus in a Population With One or Several, Primitive or Secondary, Bra NCT03673878 | University Hospital, Brest | — |
| Completed | B244 Topical Spray for the Treatment of Pruritus in Adults With a History of Atopic Dermatitis NCT04490109 | AOBiome LLC | Phase 2 |
| Unknown | A Study of SHR0410 in Hemodialysis Patients With Pruritus NCT04317209 | Jiangsu HengRui Medicine Co., Ltd. | Phase 1 |
| Completed | Non-pharmacological Mitigation of Psoriasis NCT04745429 | Medical University of Lodz | N/A |
| Completed | The Effect of Midazolam on Dexamethasone-induced Perineal Pruritus NCT04326738 | Yangzhou University | EARLY_Phase 1 |
| Completed | Influence of H1-antihistamines on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin. NCT04399525 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Completed | Pruritus and Melanoma and Cutaneous Carcinomas Treated With Immunotherapy NCT04365244 | University Hospital, Brest | — |
| Completed | A Study of SHR4010 in Patients With Hemodialysis NCT04099927 | Jiangsu HengRui Medicine Co., Ltd. | Phase 1 |
| Completed | Topical Acetaminophen for Itch Relief: a Proof of Concept Study in Healthy Subjects NCT03997851 | University of Miami | Phase 1 / Phase 2 |
| Completed | Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Sub NCT04018027 | Cara Therapeutics, Inc. | Phase 2 |
| Completed | Influence of Antipruritics on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin. NCT04399148 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Completed | Frequency and Characteristics of Pruritus in Patients With Monoclonal Gammopathy NCT03832140 | University Hospital, Brest | — |
| Completed | Study Determining Safety and Efficacy of Avena Sativa (Oat) Skincare Products for Treating Skin Dryness and It NCT03796052 | Johnson & Johnson Consumer Inc. (J&JCI) | N/A |
| Completed | A Trial of SHR0410 Injection in Hemodialysis Participants. NCT03857568 | Atridia Pty Ltd. | Phase 1 |
| Completed | Inter-arm and Inter-period Reproducability of the Dermal Blood Flow Response After a Histamine Skin Prick. NCT04396977 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Completed | Study of the Efficacy, Safety, and Tolerability of Serlopitant for the Treatment of Chronic Pruritus of Unknow NCT03841331 | Vyne Therapeutics Inc. | Phase 2 |
| Completed | Dermal Blood Flow Response to Escalating Doses of Histamine, Administered by a Skin Prick NCT04399213 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Completed | Study to Evaluate ASN008 Topical Gel (TG) NCT03798561 | Asana BioSciences | Phase 1 |
| Completed | Study Evaluating the Benefit of Music Therapy on Pruritus in Patients With Pruritic Dermatitis NCT03701971 | University Hospital, Brest | N/A |
| Completed | Enhancing SKIN Health and Safety in Aged CARE NCT03824886 | PD Dr. Jan Kottner | N/A |
| Completed | Scalp Pruritus Measurement Using Visual Analog Scale and 5-d Itch Scale in Children With Pediculosis Capitis NCT04415034 | Indonesia University | — |
| Completed | Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Prurig NCT03677401 | Vyne Therapeutics Inc. | Phase 3 |
| Completed | Scratch and Sleep Quantification in Atopic Dermatitis NCT03490877 | University of Rochester | — |
| Completed | A Study to Evaluate the Safety and Efficacy of CR845 in Chronic Kidney Disease Patients With Moderate-to-Sever NCT03617536 | Cara Therapeutics, Inc. | Phase 2 |
| Completed | Effect of Granisetron on Morphine Induced Pruritus in Cesarean Section NCT03483870 | Assiut University | Phase 2 |
| Completed | Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Prurig NCT03546816 | Vyne Therapeutics Inc. | Phase 3 |
| Withdrawn | A Study of the Efficacy and Safety of Orvepitant in Subjects With Pruritus Associated With Atopic Dermatitis NCT03464526 | Nerre Therapeutics Ltd. | Phase 2 |
| Terminated | Study of the Long Term Safety of Serlopitant for the Treatment of Pruritus (Itch) NCT03540160 | Vyne Therapeutics Inc. | Phase 3 |
| Completed | Acupuncture for Prevention of Itch in Caesarean Section NCT03458572 | Sheffield Teaching Hospitals NHS Foundation Trust | N/A |
| Completed | Safety, Tolerability and Efficacy of SNA-120 for Treatment of Pruritus and Psoriasis in Subjects Treated With NCT03448081 | Sienna Biopharmaceuticals | Phase 2 |
| Terminated | Does IV Ondansetron Prevent Pruritus After Intrathecal Morphine in Pediatric Patients? NCT03262038 | University of Michigan | Phase 4 |
| Completed | Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Plaque NCT03343639 | Vyne Therapeutics Inc. | Phase 2 |
| Unknown | Mechanisms of Action of Photo(Chemo)Therapy in Skin Diseases NCT03340155 | Medical University of Graz | N/A |
| Completed | Safety, Efficacy, and Tolerability of SNA-120 in Subjects With Pruritus Associated With Psoriasis Vulgaris NCT03322137 | Sienna Biopharmaceuticals | Phase 2 |
| Terminated | Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine NCT03096444 | Gil Yosipovitch | Phase 2 |
| Completed | Evaluate the Efficacy and Safety of HL151 Versus Talion Tab. in Pruritus Cutaneus NCT03317301 | Hanlim Pharm. Co., Ltd. | Phase 3 |
| Unknown | Desensitization of Nociceptive Afferents by Application of Topical Capsaicin, Trans-cinnamaldehyde and L-menth NCT03132142 | Aalborg University | N/A |
| Completed | The Color of Itch; Itch Modification by Color Viewing NCT03928223 | University Hospital, Basel, Switzerland | — |
| Completed | In-Use Test With a Cosmetic Product to Treat Pruritus NCT03477058 | Dr. August Wolff GmbH & Co. KG Arzneimittel | N/A |
| Completed | Quality of Recovery After Dexamethasone, Ondansetron or Placebo Intrathecal Morphine Administration NCT03035942 | Pontificia Universidade Catolica de Sao Paulo | Phase 4 |
| Terminated | Study of the Efficacy, Safety & Tolerability of Serlopitant for Pruritus (Itch) After Burn Injury NCT02975271 | Vyne Therapeutics Inc. | Phase 2 |
| Completed | Study of the Efficacy, Safety, and Tolerability of Serlopitant for Pruritus (Itch) in Atopic Dermatitis NCT02975206 | Vyne Therapeutics Inc. | Phase 2 |
| Completed | Neurokinin-1 Receptor Antagonist for the Treatment of Itch in EB Patients NCT02654483 | Jean Yuh Tang | Phase 2 |
| Completed | A Study to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-SK-1405 NCT02846181 | Sanwa Kagaku Kenkyusho Co., Ltd. | Phase 1 |
| Completed | Pruritus and Pemphigoid in Nursing Home Patients NCT02823067 | M.F. Jonkman | — |
| Completed | Ondansetron vs Ondansetron Plus Dexamethasone for Relieving Intrathecal Morphine Side Effects After C-section NCT02793843 | Makassed General Hospital | N/A |
| Completed | Effects of High-concentration Topical Capsaicin on Histaminergic and Non-histaminergic Itch NCT02769910 | Hjalte Holm Andersen | Phase 1 / Phase 2 |
| Completed | Itch and Clinacal Caracteristics in Systemic Sclerosis NCT03297580 | University Hospital, Brest | — |
| Completed | Itch Relieving Effect of Botox: a Study in Healthy Subjects NCT02639052 | Temple University | Phase 1 / Phase 2 |
| Completed | A Study to Investigate the Receptor Occupancy of SK-1405 in Healthy, Caucasian, Male Subjects NCT02650076 | Sanwa Kagaku Kenkyusho Co., Ltd. | Phase 1 |
| Completed | Evaluating the Effect of Fumaria Parviflora L. in Uremic Pruritus NCT02671162 | Shiraz University of Medical Sciences | Phase 2 |
| Completed | Safety, Pharmacokinetics and Preliminary Efficacy of Asimadoline in Pruritus Associated With Atopic Dermatitis NCT02475447 | Tioga Pharmaceuticals | Phase 2 |
| Completed | Non Interventional Clinical Investigation of Ectoin Ear Spray in Skin Treatment of Outer Ear Canal Irritations NCT02558738 | Bitop AG | — |
| Completed | Itch and Pain Characteristics in Skin Carcinomas NCT03290989 | University Hospital, Brest | — |
| Completed | Study of Nalbuphine HCl ER Tablets in Patients With Prurigo Nodularis NCT02174419 | Trevi Therapeutics | Phase 2 / Phase 3 |
| Withdrawn | Impact of Vorinostat on Pruritus Signaling Pathways - Merck Study NCT01801670 | Boston University | — |
| Completed | L-menthol as a Topical Counter-irritant to TRPA1-induced Neurogenic Inflammation and Pain NCT02653703 | Aalborg University | N/A |
| Unknown | Efficacy of Laser Acupuncture on Pruritus in Patients With Chronic Kidney Disease Undergoing Hemodialysis NCT02432508 | China Medical University Hospital | N/A |
| Terminated | Study of Using Long Acting Antihistamine to Treat Opioid Induced Itching NCT01825655 | Virginia Commonwealth University | Phase 4 |
| Completed | Open Label Extension Study of Nalbuphine HCl ER in Hemodialysis Patients With Uremic Pruritus NCT02143973 | Trevi Therapeutics | Phase 2 / Phase 3 |
| Completed | Safety and Pharmacokinetics of IV CR845 in Hemodialysis Patients, and Its Efficacy in Patients With Uremic Pru NCT02229929 | Cara Therapeutics, Inc. | Phase 2 |
| Completed | Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritus NCT02143648 | Trevi Therapeutics | Phase 2 / Phase 3 |
| Completed | Serum Serotonin and Pruritus After Intrathecal Morphine in Cesarean Section NCT03209427 | Assiut University | Phase 4 |
| Completed | Topical Aprepitant in Prurigo Patients NCT01963793 | LEO Pharma | Phase 2 |
| Completed | Comparison of Epidural Oxycodone and Epidural Morphine NCT02277678 | KK Women's and Children's Hospital | Phase 3 |
| Completed | Study of Itch Control by VLY-686 in Healthy Volunteers After Intradermal Injections of Substance P NCT01919944 | Vanda Pharmaceuticals | Phase 1 |
| Completed | Blinded, Randomized Study Evaluating Aurstat Versus Control in the Treatment of Atopic Dermatitis Associated P NCT01905631 | The Center for Clinical and Cosmetic Research | Phase 2 |
| Terminated | Efficacy of Extended-release, Once Daily Tramadol for Post Operative Analgesia in Shoulder Arthroscopy NCT02247648 | Centre hospitalier de l'Université de Montréal (CHUM) | Phase 2 |
| Completed | Effects of Transcranial Direct Current Stimulation (tDCS) on Neuropathic Symptoms Following Burn Injury NCT01795079 | Spaulding Rehabilitation Hospital | N/A |
| Unknown | Acticoat Absorbent and BCT Antimicrobial for STSG Donor Site on Thigh NCT01769144 | Kaohsiung Veterans General Hospital. | N/A |
| Terminated | Study to Assess the Clinical Activity of a Sequential Dose of REGN846 on Refractory Pruritus in Patients With NCT01605708 | Regeneron Pharmaceuticals | Phase 1 / Phase 2 |
| Terminated | Effect of Neurokinin-1 Receptor (NK1R) Antagonism on Pruritus in Patients With Sezary Syndrome NCT01625455 | Vanderbilt University Medical Center | Phase 4 |
| Completed | Evaluating the Effect of Senna in Uremic Pruritus NCT02008864 | Shiraz University of Medical Sciences | N/A |
| Completed | Pruritus in Patients With Chronic Kidney Disease NCT01727180 | Far Eastern Memorial Hospital | — |
| Completed | PK Comparisons of Bepotastine Besilate 10 mg and Bepotastine Salicylate 9.64 mg NCT01897428 | Korea University Anam Hospital | Phase 1 |
| Completed | Safety Study of Levocetirizine and Fexofenadine NCT01586091 | Charite University, Berlin, Germany | Phase 4 |
| Completed | Naloxone for the Treatment of Opioid-Induced Pruritus NCT01071057 | University of British Columbia | Phase 2 / Phase 3 |
| Unknown | Explore the Mechanisms of Pruritus in Bullous Pemphigoid Patients During Remission NCT01265082 | National Taiwan University Hospital | — |
| Completed | Efficacy and Tolerability Study of Device, RD047-26 for the Treatment of Mild to Moderate Atopic Dermatitis in NCT01232985 | Oculus Innovative Sciences, Inc. | Phase 2 |
| Completed | Gabapentin for Prophylaxis Intrathecal Morphine-Induced Pruritus NCT01236859 | Prince of Songkla University | N/A |
| Withdrawn | Gabapentin for the Treatment of Pruritus Caused by Burn Injuries in Children NCT01092520 | The Hospital for Sick Children | Phase 1 |
| Completed | Intrathecal Morphine for Inguinal Hernia Repair. NCT02001948 | Ankara University | Phase 4 |
| Completed | Management of Pruritus With Xyzal in Atopic Dermatitis NCT00884325 | Derm Research, PLLC | Phase 4 |
| Completed | Evaluating the Effect of Cromolyn Sodium in Uremic Pruritus NCT00745199 | Shiraz University of Medical Sciences | Phase 2 |
| Completed | Observation of Use of Claritin (Loratadine) Tablet, RediTabs, and Dry Syrup in Children (Study P05834)(COMPLET NCT00762983 | Merck Sharp & Dohme LLC | — |
| Unknown | An Observational Study of Pruritus Amongst Hemodialysis Patients NCT00715260 | Acologix, Inc. | — |
| Completed | Hydroxyzine for the Prevention of Pruritus From Spinal Morphine in Transabdominal Hysterectomy Patients NCT01055236 | Mahidol University | Phase 4 |
| Completed | Evaluation of Post Burn Rehabilitation Population for Itch Control NCT00782054 | Swiss-American Products, Inc | Phase 4 |
| Completed | Uremic Pruritus, Cytokines and Polymethylmethacrylate Artificial Kidney NCT00442819 | China Medical University Hospital | Phase 4 |
| Completed | Epidemiology and Control of Mansonella Perstans Infection in Uganda NCT00215280 | DBL -Institute for Health Research and Development | N/A |
| Unknown | Gabapentin - A Solution to Uremic Pruritus? NCT00577967 | Hospital Authority, Hong Kong | N/A |
| Completed | Study Of Cutaneous Disease Accompanied With Pruritus In Pediatrics NCT00257582 | GlaxoSmithKline | Phase 3 |
| Completed | Fexofenadine in Pruritic Skin Disease NCT00261079 | Handok Inc. | Phase 4 |
| Completed | Optimal Dose of Prophylactic Naloxone in Reducing Opioid-Induced Side Effects in Children/Adolescents NCT00330343 | Johns Hopkins University | Phase 2 |
| Completed | Treatment of Cholestatic Pruritus With Sertraline NCT00058903 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 2 |
| Completed | Study of Effectiveness of Mexyn-A NCT00568204 | Evangelical Synod Medical Centre | N/A |
| Completed | Gabapentin to Treat Itch in Patients With Liver Disease NCT00058890 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 3 |
| Available | Linerixibat Compassionate Use for Cholestatic Pruritus Adult Patients With Primary Biliary Cholangitis (PBC) NCT05448170 | GlaxoSmithKline | — |