Trials / Completed
CompletedNCT04396977
Inter-arm and Inter-period Reproducability of the Dermal Blood Flow Response After a Histamine Skin Prick.
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 14 (actual)
- Sponsor
- Universitaire Ziekenhuizen KU Leuven · Academic / Other
- Sex
- Male
- Age
- 18 Years – 45 Years
- Healthy volunteers
- Accepted
Summary
To evaluate the inter-arm and inter-period reproducibility of the dermal blood flow response induced by a skin prick of histamine, subjects will receive histamine (10 mg/ml) and negative control skin pricks on the volar surface of both forearms during two subsequent study visits to allow an intra-individual comparison. Changes in dermal blood flow will be measured during the hour after the skin pricks with laser Doppler and/or laser speckle contrast imaging.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Histamine 10 mg/ml skin prick | Skin prick through 5 µL histamine diHCl (10 mg/ml) |
| PROCEDURE | Placebo (saline) skin prick | Skin prick through 5 µL saline (0.9% NaCl) |
Timeline
- Start date
- 2019-02-28
- Primary completion
- 2019-05-07
- Completion
- 2019-05-07
- First posted
- 2020-05-21
- Last updated
- 2020-05-21
Locations
1 site across 1 country: Belgium
Source: ClinicalTrials.gov record NCT04396977. Inclusion in this directory is not an endorsement.