Trials / Completed
CompletedNCT04805073
Treatment of Pruritus With Intramuscular Promethazine
Assessing Efficacy of Intramuscular Promethazine for the Treatment of Intrathecal Morphine Induced Pruritus
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 72 (actual)
- Sponsor
- University of Florida · Academic / Other
- Sex
- Female
- Age
- 18 Years – 99 Years
- Healthy volunteers
- Accepted
Summary
Neuraxial narcotics are commonly used in obstetric patients for cesarean delivery to help with pain control over the first 24 hours after the surgery. The aim is to evaluate effectiveness of promethazine (IMP) treatment of intrathecal morphine induced pruritus (ITIMIP). A treatment for ITMIP, other than naloxone, will allow for increased use of intrathecal narcotics and decrease the use of systemic opioids in the initial post-operative period.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Promethazine | 1cc 25mg/ml Promethazine (study medication) |
| DRUG | Placebo | 1cc 0.9% Sodium Chloride (placebo) |
Timeline
- Start date
- 2021-08-09
- Primary completion
- 2024-05-30
- Completion
- 2024-05-30
- First posted
- 2021-03-18
- Last updated
- 2025-05-04
- Results posted
- 2025-05-04
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT04805073. Inclusion in this directory is not an endorsement.