NCT05678309

Establishment of a Patient Library in Patients With Pruritus Sine Materia

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 175 (estimated)
• Sponsor: University Hospital, Brest · Academic / Other
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

Very little is currently known about the pathophysiology of pruritus sine materia according to the etiology. The creation of this cohort should make it possible to improve our clinical and biological knowledge according to the etiology, by collecting blood, skin, feces, and clinical data.

Detailed description

At inclusion, 52.5 ml of blood will be collected, then an additional skin biopsy and a skin swab. Five questionnaires will be filled in by the patient. At 6 months, then every years for 5 years, the same 5 questionnaires will be collected as well as the clinical data. However, no more biological samples will be collected.

Conditions

• Pruritus
• Chronic Pruritus
• Itch

Interventions

Type	Name	Description
OTHER	Blood samples	At inclusion : * 52.5 ml of blood : * 24 ml plasma * 20 ml serum * 6 ml DNA * 2.5 ml RNA
OTHER	skin swab sample	At inclusion a skin swab sample will be collected
OTHER	skin biopsy sample	At inclusion a skin biopsy sample will be collected
OTHER	Questionnaires	At inclusion, at 6 months and every year, the patient will respond to 5 questionnaires : Brest questionnaire, 5-D itch scale, Dermatology Life Quality Index, Itchy Quality of Life and Hospital Anxiety and Depression Scale

Timeline

• Start date: 2023-04-01
• Primary completion: 2033-02-01
• Completion: 2033-02-01
• First posted: 2023-01-10
• Last updated: 2023-04-03

Locations

1 site across 1 country: France