NCT02001948

Intrathecal Morphine for Inguinal Hernia Repair.

The Comparison of Two Different Doses of Morphine Added to Spinal Bupivacaine for Inguinal Hernia Repair.

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 46 (actual)
• Sponsor: Ankara University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study was to compare the effects of two different doses of intrathecal morphine (0.1 mg and 0.4 mg) combined with 7.5 mg of heavy bupivacaine on postoperative block regression times, postoperative analgesia and the severity of side effects, for inguinal hernia repairs.

Detailed description

The purpose of this study was to compare spinal anesthesia with low dose heavy bupivacaine combined with 0.1 mg or 0.4 mg of morphine in inguinal hernia repair surgeries. Anesthesia onset time (sensory and motor blocks) as well as postoperative recovery (first mobilisation, first voiding) time were compared. Also the postoperative pain management and side effects (nausea, vomiting and pruritus) were assessed.

Conditions

• Inguinal Hernia
• Nausea
• Vomiting
• Pruritus
• Postoperative Pain

Interventions

Type	Name	Description
DRUG	intrathecal morphine 0.1 mg combined with intrathecal heavy bupivacaine 7.5 mg
DRUG	intrathecal morphine 0.4 mg combined with intrathecal heavy bupivacaine 7.5 mg
DEVICE	standard monitoring with Datex Ohmeda anesthesia monitor, GE, Finland	electrocardiography, heart rate, pulse oximetry and noninvasive arterial blood pressure
DRUG	intravenous cannulation and premedication	18-gauge intravenous cannula was inserted at the forearm opposite to the surgical side and routine iv premedication (midazolam 0.03 mg/kg) was given

Timeline

• Start date: 2009-07-01
• Primary completion: 2010-07-01
• Completion: 2010-07-01
• First posted: 2013-12-05
• Last updated: 2013-12-05

Locations

1 site across 1 country: Turkey (Türkiye)