| Withdrawn | Feasibility of a Novel Resistance Exercise in Individuals With Osteoporosis NCT05060380 | University of Alabama at Birmingham | N/A |
| Not Yet Recruiting | Study in Patients With Osteoporosis and Fragility Fractures to Estimate the Extent and Impact of Delayed Admin NCT07512453 | Azienda Ospedaliero, Universitaria Pisana | — |
| Not Yet Recruiting | The Comparison of Ibandronate and Zoledronic Acid After Denosumab Discontinuation NCT07406685 | National Taiwan University Hospital | Phase 4 |
| Recruiting | The Osteoporotic Fracture Classification-based Scoring System for Treatment Decision in Thoracolumbar Osteopor NCT07027306 | AO Foundation, AO Spine | — |
| Not Yet Recruiting | U.S. Prospective Evaluation of EPIONE Device for Percutaneous MSK Procedures NCT07325578 | Quantum Surgical | N/A |
| Enrolling By Invitation | Contribution of Bone to Urine Citrate NCT06811363 | University of Texas Southwestern Medical Center | — |
| Not Yet Recruiting | Evaluation of Dora Care for Supporting Fracture Liaison Services (FLS) NCT07464171 | Ufonia | N/A |
| Not Yet Recruiting | Study on the Intervention Effect of Denosumab on High-Risk Patients With Osteoporotic Fractures in Type 2 Diab NCT07063797 | Peking Union Medical College Hospital | N/A |
| Recruiting | Patient Education in Osteoporosis (RCT-PATOS) NCT07367776 | University Hospital, Linkoeping | N/A |
| Recruiting | OsteoPorotic fracTure preventION System (OPTIONS) Research Study NCT06731608 | Brigham and Women's Hospital | N/A |
| Not Yet Recruiting | AGE Burden and Response to Antiresorptive Therapy in Osteoporosis NCT07329543 | Bursa City Hospital | — |
| Recruiting | Step-down Therapy After Long-term Osteoporosis Treatment NCT07281586 | National Taiwan University Hospital | Phase 4 |
| Completed | AI-Generated Audiovisual Education and Osteoporosis Knowledge NCT07436000 | Kars State Hospital | N/A |
| Recruiting | Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine NCT07083557 | Bettina Mittendorfer | — |
| Recruiting | Comparison of Bone Mineral Density in the Third Trimester Between Women in Singleton and Twin Pregnancies Usin NCT07508553 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | N/A |
| Recruiting | REMS25: Study on the Use of REMS Technology in Diseases Commonly Associated With Reduced Bone Mineral Density NCT07412782 | Meyer Children's Hospital IRCCS | N/A |
| Recruiting | Romosozumab and Denosumab, Alone or Combined, in Postmenopausal Osteoporosis NCT07283887 | National Taiwan University Hospital | Phase 4 |
| Recruiting | Clinical Study to Estimate Bone Mineral Density With the POROUS Ultrasound Device NCT07187518 | POROUS GmbH | N/A |
| Recruiting | Chiropractor Delivered Virtual Intervention After Vertebral frActure NCT07288684 | University of Waterloo | N/A |
| Enrolling By Invitation | Compare the Pharmacokinetics, Pharmacodynamics, Safety and Immunogenicity of SAL023 and Italy-Manufactured Eve NCT07384104 | Shenzhen Salubris Pharmaceuticals Co., Ltd. | Phase 1 |
| Recruiting | GLP-1R Actions on Muscle and the Skeleton NCT07154719 | Pennington Biomedical Research Center | Phase 4 |
| Recruiting | Bone Turnover Markers and Treatment Efficacy in Postmenopausal Osteoporosis NCT07242612 | Khyber Medical University Peshawar | N/A |
| Recruiting | Impact of Screening and Multicomponent Exercise on Fall Rates, Fractures, and Cardiovascular Health in Diabete NCT06745544 | Aalborg University Hospital | N/A |
| Recruiting | Generative AI Impact on Rheumatoid Arthritis Complications Diagnosis NCT07301892 | Guang'anmen Hospital of China Academy of Chinese Medical Sciences | — |
| Withdrawn | Study to Compare the Efficacy, Pharmacokinetics, Pharmacodynamics, Safety, and Immunogenicity of MAB-22 Versus NCT06504966 | Xentria, Inc. | Phase 3 |
| Not Yet Recruiting | The Effect of Semaglutide on Bone Health NCT07165158 | The First Affiliated Hospital of Xiamen University | Phase 4 |
| Not Yet Recruiting | Tele-Rehabilitation Intervention in Community-Based Healthcare for Patients With Osteoporosis (DHEAL-COM-OP) NCT06984380 | Istituto Nazionale di Ricovero e Cura per Anziani | N/A |
| Recruiting | Baduanjin With Resistance Training Program NCT06853132 | Yale University | N/A |
| Not Yet Recruiting | A Clinical Study Evaluating the Dermal Safety of Soluble Denosumab Microneedle Patches NCT07085520 | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | Phase 1 |
| Recruiting | Self-questionnaire in Osteoporosis NCT07067827 | CHU de Quebec-Universite Laval | — |
| Completed | Osteoporosis After Stroke NCT07059468 | Gaziler Physical Medicine and Rehabilitation Education and Research Hospital | — |
| Recruiting | Health Literacy and Osteoporosis Awareness NCT07419451 | Bandırma Onyedi Eylül University | — |
| Not Yet Recruiting | Resting-state Imaging and OSteoporosiS NCT07030205 | University Hospital, Clermont-Ferrand | N/A |
| Not Yet Recruiting | The Relationship Between Osteoporosis and Sarcopenia Parameters in Postmenopausal Women Under 60 NCT07045012 | Beylikduzu State Hospital | — |
| Active Not Recruiting | Intravenous Infusion of Human Mesenchymal Stem Cells (HMM910 ) in Postmenopausal Women With Osteoporosis at Hi NCT06949137 | HELP Therapeutics Co., Ltd. | Phase 1 |
| Completed | Bone Density Change in Postmenopausal Rheumatoid Arthritis NCT07336693 | Istanbul University - Cerrahpasa | — |
| Not Yet Recruiting | The Oswestry Metabolic BONE Cohort NCT07014306 | Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust | — |
| Recruiting | Dairy vs Plant-based Beverages for Improving Bone Health During Exercise NCT06946316 | University of Saskatchewan | N/A |
| Not Yet Recruiting | Chronotherapeutic Optimization of Teriparatide Administration in Postmenopausal Osteoporosis NCT06951776 | Peking University Third Hospital | N/A |
| Recruiting | Orthorexia Nervosa in Postmenopausal Osteoporosis NCT06947213 | Beylikduzu State Hospital | — |
| Recruiting | Effects of Cycle Therapy vs Sequential Therapy With Romosozumab and Denosumab in Postmenopausal Osteoporosis P NCT06938152 | National Taiwan University Hospital | Phase 4 |
| Recruiting | Assessment of Mineral and Bone Disorders in Kidney Transplant Recipients NCT07141043 | Grigore T. Popa University of Medicine and Pharmacy | — |
| Not Yet Recruiting | Holistic Integration for Healthy Longevity and Aging in Place NCT06882434 | National Taiwan University Hospital | N/A |
| Recruiting | A Study of Amorphous Calcium Carbonate in Postmenopausal Women NCT06728462 | Universal Integrated Corp. | N/A |
| Recruiting | Clinical Study to Predict the Risk of Bone Fractures With the POROUS Ultrasound Device NCT06567054 | POROUS GmbH | N/A |
| Recruiting | A Prospective Observational Study of Artificial Intelligence Morphometric Evaluation of Vertebral Fractures NCT06449742 | IRCCS San Raffaele | — |
| Recruiting | Digital Implementation of the German S3 Clinical Practice Guideline for Multimorbidity NCT06831994 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Completed | Association Between Isokinetic Lower Extremity Muscle Strength and Bone Mineral Density in Elderly Women With NCT07084857 | Cairo University | — |
| Recruiting | Effect of Acetylcholinesterase Inhibitors on Bone Metabolism NCT06041789 | Duke University | Phase 2 |
| Recruiting | Combined Anabolic Therapy NCT06558188 | Massachusetts General Hospital | Phase 4 |
| Completed | Telemedicine Intention, Need, Expectations, and Perceived Challenges Among Women With Osteoporosis NCT06969313 | Antalya Training and Research Hospital | — |
| Active Not Recruiting | Virtual Intervention for Vertebral frActure: a Pilot, Feasibility Study for a Multicentre Randomized Controlle NCT06650410 | University of Waterloo | N/A |
| Not Yet Recruiting | A Single-center, Open, Randomized, Single-dose, Cross-over Bioequivalence Study to Evaluate the Effects of the NCT06753864 | The Affiliated Hospital of Qingdao University | Phase 1 |
| Enrolling By Invitation | Longitudinal Evaluation of a Fracture Liaison Service NCT06847776 | Central Hospital, Nancy, France | — |
| Recruiting | Dynamics in Bone Turnover Markers During and After Short-term Glucocorticoid Treatment in Patients With an Inf NCT06395883 | Diakonhjemmet Hospital | — |
| Recruiting | EFFECT OF CIRCUIT TRAINING ON BONE MINERAL DENSITY IN POST MENOPAUSAL PERIOD NCT06950463 | Cairo University | N/A |
| Not Yet Recruiting | Prevalence of Osteoporosis Among Inflammatory Bowel Disease Patients in Assiut University Hospitals NCT06600334 | Dina Fathy | — |
| Recruiting | RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE NCT06455085 | University of Alabama at Birmingham | N/A |
| Active Not Recruiting | Incidence of Fragility Fractures and Osteoporosis Screening in Chronic Stroke Patients NCT06804252 | University of Palermo | — |
| Not Yet Recruiting | Mobility Assessment in Multi-morbidity NCT06473168 | Northumbria University | — |
| Recruiting | Qualitative Study Exploring the Determinants Involved in the Management of Osteoporosis in Frail Elderly Peopl NCT07303166 | University Hospital, Strasbourg, France | — |
| Enrolling By Invitation | Skeletal Maturation and Endocrine Health in Young Adults NCT06509776 | Holbaek Sygehus | — |
| Completed | Effect of Wii Fit Balance Board Games on Balance in Patients With Osteoporosis Post Mastectomy NCT07364279 | Cairo University | N/A |
| Completed | A Study of TeriQ Patch in Healthy Adult Female Participants NCT06644040 | QuadMedicine | Phase 1 |
| Completed | Investigation of Knowledge and Practices Regarding Pediatric Osteoporosis in Türkiye NCT06699225 | Fatih Sultan Mehmet Training and Research Hospital | — |
| Not Yet Recruiting | Digital Diagnostics and Intervention Services for Parkinson's Disease NCT06534177 | University of Exeter | — |
| Recruiting | Nurse-led Primary Healthcare Intervention Model in Women's Health Management in Hong Kong NCT06628388 | The University of Hong Kong | N/A |
| Completed | SB: Promoting Bone Health in Women NCT06843486 | Instituto Politécnico de Bragança | Phase 1 / Phase 2 |
| Enrolling By Invitation | Prevention of Injury in Skilled Nursing Facilities Through Optimizing Medications NCT06304428 | Duke University | N/A |
| Completed | Balance and Muscle Strength as Indicators of Fracture Risk in Postmenopausal Women NCT06645600 | Beylikduzu State Hospital | — |
| Recruiting | Primary Care Management of Osteoporosis in Older Women NCT06431867 | Bradford Institute for Health Research | — |
| Recruiting | Physical Activity Guarantees Bone Density. NCT06606769 | Poznan University of Physical Education | N/A |
| Recruiting | AI Model for Bone Mineral Density Prediction From X-Ray Images NCT06652061 | Bangladesh University of Engineering and Technology | — |
| Not Yet Recruiting | Effectiveness of Smart-Video Based Game Therapy and Otago-Based Structured Exercises in Women With Osteoporosi NCT06506409 | Medipol University | N/A |
| Not Yet Recruiting | The Effect of Digital Education for Osteoporosis Patients on Fracture Risk and Related Health Outcomes. NCT06603545 | Sahlgrenska University Hospital | N/A |
| Recruiting | Impact of Milk and Yogurt Supplementation on Bone Health, Body Composition, and Gut Microbiota in Canadian You NCT06265246 | University of Saskatchewan | N/A |
| Recruiting | Romosozumab Versus Denosumab in GIOP: a 2-year Extension Study NCT06472050 | Tuen Mun Hospital | Phase 4 |
| Recruiting | Synbiotic to Attenuate Resorption of the Skeleton NCT06389539 | Hebrew SeniorLife | N/A |
| Completed | Effects of Increased Greek Yogurt Consumption in Senior Adults NCT06530394 | Brock University | N/A |
| Active Not Recruiting | Evaluation of Efficacy and Safety of Prolia in Subjects of Male Osteoporosis in Mainland China NCT06332014 | Amgen | Phase 4 |
| Recruiting | Peripheral Mononuclear Cells to Screen, Monitor and Stratify the Population at Risk of Osteoporosis and Fractu NCT06551155 | Istituto Ortopedico Rizzoli | — |
| Not Yet Recruiting | Effects of First-Line Oral Hypoglycemics in Bone Markers of Treatment Naïve Saudi Adults With Type 2 Diabetes NCT06439758 | King Saud University | Phase 4 |
| Not Yet Recruiting | The Added Value of Bone Microstructure Assessment in the Management of Osteoporotic Bone NCT06513442 | Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust | — |
| Completed | Yoga Improves Bone Density and Metabolism in Elderly Osteoporosis NCT07126002 | Beijing Sport University | N/A |
| Not Yet Recruiting | Studying Patient Experiences in Osteoporosis Clinical Trials NCT05937945 | Power Life Sciences Inc. | — |
| Recruiting | Investigation of Q Angle in Osteoporosis Patients NCT06475794 | Firat University | — |
| Recruiting | The PREVENT Trial: a Pragmatic Cluster Randomized Controlled Trial of a Multifaceted Fracture Prevention Model NCT04947722 | McMaster University | N/A |
| Recruiting | Calibr-Ì: Comparative Evaluation of Phantomless Calibration Methods to Quantify Bone Mineral Density for Oppor NCT06454617 | Istituto Ortopedico Rizzoli | — |
| Completed | The Long-term Effect of Daily Jarlsberg Cheese Intake in Patient With Osteopenia NCT06358443 | Meddoc | N/A |
| Completed | "Living an Active Life with Osteoporosis" - a Digital Patient Education Program on Osteoporosis. a Feasibility NCT06729424 | University Hospital, Linkoeping | N/A |
| Not Yet Recruiting | A Study on the Prevention and Treatment of GIOP With Eldecalcitol NCT06385093 | Chinese SLE Treatment And Research Group | Phase 4 |
| Completed | The Effect of Long-term Use of Bisphosphonates on Femur Morphology NCT06621069 | Second Affiliated Hospital, School of Medicine, Zhejiang University | — |
| Recruiting | The Effect of Denosumab on Muscle and Strength and Insulin Sensitivity NCT07271771 | Aarhus University Hospital | Phase 4 |
| Completed | Insomnia in Postmenopausal Osteoporosis NCT06646549 | Beylikduzu State Hospital | — |
| Recruiting | A Pilot Study of Vitamin K2 (Menaquinone-7, Soloways ™) in Patients With Osteopenia/Osteoporosis Carrying a VD NCT06867952 | S.LAB (SOLOWAYS) | N/A |
| Recruiting | Comparison of Computed Tomography Data With Routine Measurements Concerning Bone and Muscle Health of Aged Ind NCT06488872 | University Department of Geriatric Medicine FELIX PLATTER | — |
| Recruiting | EffCaMgCit to Prevent Mineral Metabolism and Renal Complications of Chronic PPI Therapy NCT05998863 | University of Texas Southwestern Medical Center | Phase 3 |
| Recruiting | Effects of Liposomal Encapsulation on Calcium Powder Absorption and Metabolism NCT06372158 | National Yang Ming Chiao Tung University | N/A |
| Completed | Effect of Aerobic Exercise Versus Resistance Exercise on Bone Density in Postmenopausal Diabetic Women NCT06505044 | Deraya University | N/A |
| Unknown | Comparison of Detection Rates Between Two Commonly Used Bone Density Measurement Methods NCT06299865 | Xiaoqian Zhang | — |
| Recruiting | Preserving Geriatric Muscle With an Osteoporosis Medication NCT06118905 | Susan L. Greenspan | Phase 4 |
| Active Not Recruiting | Time-specific Exercise in Circadian Context NCT06746649 | Comenius University | N/A |
| Unknown | Clinical Controlled Study on the Efficacy of Denosumab in Treating Osteoporosis in the Domestic Population and NCT06154707 | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | Phase 3 |
| Enrolling By Invitation | Precision Medicine Approach for Osteoporosis - Follow Up Study NCT06264609 | Paul F Netzel | Phase 4 |
| Unknown | Study to Evaluate the Efficacy and Safety of PBK_L2201 in Postmenopausal Women With Osteoporosis NCT06154187 | Pharmbio Korea Co., Ltd. | Phase 3 |
| Withdrawn | Comparison of the Effectiveness of a Web Fracture Liaison Service (e_FLS) to Fracture Liaison Services in Fran NCT05303350 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Kinesiophobia in Postmenopausal Osteoporosis NCT06520709 | Beylikduzu State Hospital | — |
| Recruiting | A Study to Improve the Collaboration Between Primary and Secondary Health Care on the Treatment of Osteoporosi NCT05904353 | University Hospital, Akershus | N/A |
| Completed | Effectiveness of a Web-Based Osteoporosis Awareness Education Program Based on the Health Belief Model Among F NCT06977776 | Kirsehir Ahi Evran Universitesi | N/A |
| Withdrawn | Exercise and Posture in Individuals with Osteoporosis NCT04509427 | University of Alabama at Birmingham | N/A |
| Unknown | Awareness of Osteoporosis in Ankylosing Spondylosis Patients NCT05760105 | Uskudar State Hospital | — |
| Recruiting | Clinical Validation of BBCT-hip NCT06270758 | Istituto Ortopedico Rizzoli | — |
| Completed | Effectiveness of the Adherence for Exercise Rehabilitation in Older People (AERO) Program in People with Osteo NCT06164847 | Hochschule Osnabruck | N/A |
| Active Not Recruiting | Strength Training for Osteoporosis Prevention During Early Menopause NCT05961371 | University of Calgary | N/A |
| Active Not Recruiting | Effectiveness of Implementation of Opportunistic AI-screening for Vertebral Fractures in Clinical Practice NCT07100756 | University Hospital, Linkoeping | — |
| Completed | Awareness of Osteoporosis in Multiple Sclerosis Patients NCT05760651 | Uskudar State Hospital | — |
| Recruiting | Cardiovascular Risk in Digital Osteoarthritis NCT05923736 | University Hospital, Clermont-Ferrand | N/A |
| Recruiting | The Optimised Use of Romozosumab Study NCT06059222 | University of Aarhus | Phase 4 |
| Recruiting | The Impact of Hormonal Contraceptive Use and Lifestyle Factors on Fracture Risk and Bone Quality in Young Fema NCT06608862 | Bundeswehr University Munich | — |
| Not Yet Recruiting | Relation Between NAFLD and BM DENSITY NCT06038253 | Assiut University | — |
| Recruiting | Surgeon-Initiated Bone Health Referral Pathway in Patients Undergoing Lower Extremity Arthroplasty NCT05845021 | Johns Hopkins University | N/A |
| Unknown | Risk of Osteoporotic Fracture in Home Care Patients in Turkey NCT05738785 | Uskudar State Hospital | — |
| Recruiting | Smart Wearable Device (gaitQ): Walk Better Project NCT05913219 | University of Exeter | — |
| Recruiting | Osteosarcopenia in Axial Spondyloarthritis NCT06577350 | Ankara University | — |
| Completed | The Bone-Myoregulation Reflex and Development of Sarcopenia in Osteoporosis NCT06017245 | Istanbul Physical Medicine Rehabilitation Training and Research Hospital | N/A |
| Completed | Comparison of Lumbar Muscle Thickness Measurements in Osteoporotic and Osteopenic Patients NCT05823558 | Sisli Hamidiye Etfal Training and Research Hospital | — |
| Unknown | Awareness of Osteoporosis in HIV Patients NCT05769413 | Uskudar State Hospital | — |
| Enrolling By Invitation | Osteo Match Cages Versus PEEK Cages in Osteoporotic Patients NCT05981222 | Peking University Third Hospital | — |
| Unknown | Surveying Knowledge, Attitudes, and Practices of Primary Care Physicians in Turkey Regarding Osteoporosis Mana NCT05851131 | Uskudar State Hospital | — |
| Unknown | Awareness of Osteoporosis in Patients With Hepatitis B Infection NCT05768737 | Uskudar State Hospital | — |
| Recruiting | Epidemiological Study of Osteoporosis in the Elderly Population of Shandong Province NCT06915935 | The Second Hospital of Shandong University | — |
| Terminated | Bone Microarchitecture in Men With Hemophilia NCT05127681 | Hospices Civils de Lyon | N/A |
| Unknown | Awareness of Osteoporosis in Patients With Hyperthyroidism NCT05760417 | Uskudar State Hospital | — |
| Unknown | An Assessment of Treatment Adherence of Osteoporosis Patients From a Biopsychosocial Perspective NCT05943600 | Istanbul University | — |
| Unknown | Effect of Nocturnal Parenteral Nutrition on Bone Turnover and Energy Metabolism NCT05868785 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Unknown | Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SHR-2017 Injection in Po NCT05930704 | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | Phase 1 |
| Completed | Opportunistic Fragility Fracture Risk Estimates From Radiographs NCT06110442 | University of Exeter | — |
| Unknown | Awareness of Osteoporosis in Patients With Hypothyroidism NCT05760131 | Uskudar State Hospital | — |
| Unknown | Awareness of Osteoporosis in Patients With Hepatitis C Infection NCT05769400 | Uskudar State Hospital | — |
| Unknown | Recombinant Human Bone Morphogenetic Protein-2(rhBMP-2) in Patients With Osteoporosis After Lumbar Fusion NCT05911477 | Xijing Hospital | N/A |
| Unknown | Awareness of Osteoporosis in Diabetes Mellitus Patients NCT05760118 | Uskudar State Hospital | — |
| Unknown | The Living With a Long-Term Condition Study NCT06072287 | King's College London | — |
| Completed | Brief Osteoporosis Education to Increase Awareness in Middle Aged and Elderly. NCT05936177 | Selkin Yılmaz Muluk | N/A |
| Completed | Effect of Progressive Loading Protocol on Bone Mineral Density NCT05889104 | Imam Abdulrahman Bin Faisal University | N/A |
| Withdrawn | Thoracic Kyphosis and Osteoporosis: Study of Their Relationship With Respiratory Functions in Chronic Obstruct NCT04757714 | Centre Hospitalier Régional d'Orléans | N/A |
| Not Yet Recruiting | Bone Microstructure by Using HR-pQCT After Esophagectomy NCT05812235 | Nagasaki University | — |
| Completed | Assess Safety and Compare PK of New Oral hPTH(1-34) Tablet Formulations vs. EBP05 Tablets and Subcutaneous For NCT05965167 | Entera Bio Ltd. | Phase 1 |
| Active Not Recruiting | Relationship Between Thoracic Hyperkyphosis and Fall Risk in Women with Fragility Vertebral Fractures NCT06842758 | University of Palermo | — |
| Unknown | Osteoporosis Awareness in Rheumatoid Arthritis Patients NCT05740085 | Uskudar State Hospital | — |
| Unknown | PATHophysiology of OSteoporosis: Role of Hidden Cortisol Excess and Its Predictors in Bone Fragility NCT06324084 | Istituto Auxologico Italiano | — |
| Recruiting | Study of the Prevalence of Osteo-metabolic Complications in Patients With Thyroid Cancer NCT06627998 | IRCCS San Raffaele | — |
| Completed | The Effect of a 12-week Self-composed Vegan Diet With or Without Concurrent Resistance Exercise on Thigh Muscl NCT05809466 | Wageningen University | N/A |
| Completed | Bone Markers in Pediatric IF NCT05909228 | The Hospital for Sick Children | — |
| Unknown | Diagnostic Performances of Mandibular CBCT in Osteoporosis NCT05721118 | Nantes University Hospital | — |
| Active Not Recruiting | A Study of Romosozumab in Women With Multiple Myeloma and Osteoporosis NCT05775094 | Memorial Sloan Kettering Cancer Center | Phase 1 |
| Unknown | China Elderly Comorbidity Medical Database NCT06316544 | Beijing Friendship Hospital | — |
| Recruiting | Deep Phenotyping of Bone Disease in Type 2 Diabetes and Relations to Diabetic Neuropathy NCT05642143 | Aalborg University Hospital | — |
| Active Not Recruiting | Muscle Impact of Treating Osteoporosis NCT05666310 | Nami Safai Haeri | Phase 4 |
| Active Not Recruiting | Multifaceted Intervention Using Telehealth to Reduce the Risk of Falls and Fractures in Older Men NCT05927623 | McGill University Health Centre/Research Institute of the McGill University Health Centre | N/A |
| Unknown | OsteoPorosis Treatment Identification Using Machine Learning NCT05678569 | NHS Greater Glasgow and Clyde | — |
| Recruiting | OSTEOMICS: Identifying Regulators of Bone Homeostasis NCT05732870 | Relation Therapeutics | — |
| Recruiting | Structured Data Collection of Patients Undergoing Liver Transplantation and Evaluated for Bone Mineral Metabol NCT06838702 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | — |
| Unknown | Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY) NCT05473325 | Willows Health | — |
| Completed | Osteoporotic Precisely Screening Using Chest Radiograph and Artificial Neural Network (OPSCAN) NCT05721157 | National Defense Medical Center, Taiwan | N/A |
| Completed | GRACE - Study of AGN1 LOEP in Osteopenic and Osteoporotic Patients NCT05966974 | AgNovos Healthcare, LLC | — |
| Withdrawn | Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for Oste NCT05152381 | The Foundation for Orthopaedics and Regenerative Medicine | Phase 1 |
| Unknown | Effect of Focal Vibration Within a Multicomponent Exercise Program for Older Women With Osteoporosis a Single- NCT05538377 | Universitat Internacional de Catalunya | N/A |
| Active Not Recruiting | Sickle Cell Disease (SCD) Bone Pain Study NCT05283148 | University of California, Davis | N/A |
| Completed | Real-World Evidence of Adherence to Denosumab Therapy and Fracture Risk Associated With Drug Withdrawal: A Cro NCT06414616 | Trakya University | — |
| Not Yet Recruiting | Menier's Disease - Bone Density Study NCT05322538 | HaEmek Medical Center, Israel | N/A |
| Not Yet Recruiting | The Bone-parathyroid Crosstalk in Primary Hyperparathyroidism NCT05556499 | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio | — |
| Active Not Recruiting | Osteoporosis Patient Education in Denmark NCT05401968 | University of Southern Denmark | N/A |
| Terminated | Sacral Fracture Fusion/Fixation for Rapid Rehabilitation NCT05426356 | SI-BONE, Inc. | N/A |
| Active Not Recruiting | Finding the Optimal Resistance Training Intensity For Your Bones NCT05541432 | University of Waterloo | N/A |
| Completed | Efficacy of Structured Exercise-Nutritional Intervention on Sarcopenia in Patients With Osteoporosis NCT06287502 | Kowloon Hospital, Hong Kong | N/A |
| Unknown | Efficacy of Zoledronic Acid to Prevent Bone Loss Following Denosumab Discontinuation NCT05405894 | University of Calgary | — |
| Withdrawn | Quantitative Ultrasound Use to Increase Geriatric Follow-up for Osteoporosis NCT04691869 | Cedars-Sinai Medical Center | N/A |
| Completed | The iCARE Study: Education Modules for Fracture Prevention NCT05445336 | McMaster University | — |
| Recruiting | Mode of Exercise and Bone Biomarkers in Older Veterans NCT05266976 | VA Office of Research and Development | N/A |
| Completed | Assessment of Cortical Bone Mechanics Technology (CBMT) Fracture Discrimination Capability NCT05721898 | Ohio University | — |
| Completed | Evaluation of Balance and Functionality in Postmenopausal Osteoporosis Using Quadriceps Femoris Muscle Thickne NCT06760598 | Istanbul University - Cerrahpasa | — |
| Completed | A First-in-Human Study Evaluating AGA2118 in Men and Postmenopausal Women NCT05225857 | Angitia Biopharmaceuticals | Phase 1 |
| Completed | A Comparison of Serum and Urine N-telopeptide Marker NCT05326815 | The Cleveland Clinic | — |
| Completed | Prevalence and Associated Factors of Sarcopenia Among Elderly Patients in Osteoporosis Clinic NCT05688150 | Kowloon Hospital, Hong Kong | — |
| Unknown | A Phase III Clinical Study of Minodronate Tablets in Postmenopausal Women With Osteoporosis NCT05305183 | Shandong New Time Pharmaceutical Co., LTD | Phase 3 |
| Unknown | Effect of a Multicomponent Intervention on Functional Capacity After Hip Fracture NCT05435534 | Fundacion Miguel Servet | N/A |
| Unknown | Prevalence of Hidden Hypercortisolism in Osteoporosis NCT05762549 | Istituto Auxologico Italiano | — |
| Unknown | Study Evaluating Denosumab on Vascular and Bone Metabolism in Osteoporotic Chronic Kidney Disease (HDENOBS) NCT05234047 | University Hospital, Montpellier | — |
| Completed | Incidence of the Treatment faIlure in Osteoporosis NCT05499403 | Centre Hospitalier Universitaire Vaudois | — |
| Unknown | TST002 Intervenous Injection in Postmenopausal Women and Men With Reduced Bone Mineral Density NCT05391776 | HJB (Hangzhou) Co., Ltd. | Phase 1 |
| Completed | Mitigation of Major Hip Injury Due to Fall With a Smart Belt NCT05245097 | ActiveProtective Technologies, Inc | N/A |
| Completed | Effects of DHEA and Exercise on Bone Marrow Fat in Postmenopausal Women NCT05316272 | University of Colorado, Denver | N/A |
| Unknown | Study to Document the Phenomenon of Vitamin D Deficiency and Its Added Value in Patients with Low-energy Osteo NCT06643650 | National and Kapodistrian University of Athens | — |
| Unknown | Resistance Exercise Training to Improve Bone and Articular Cartilage Health in Women NCT05889598 | Loughborough University | N/A |
| Completed | Study to Investigate the Efficacy and Safety After Administration of Daewoong Zoledronic Acid for the Purpose NCT05614778 | Daewoong Pharmaceutical Co. LTD. | — |
| Unknown | Application of BHOHB SPINAL-METER and CervicalMeter for Posture Assessment NCT06012032 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Completed | A Clinical Trial to Evaluate Efficacy of Once or Twice ZOledronic Acid After Different Duration of denOsumMab NCT05361408 | Yonsei University | Phase 4 |
| Recruiting | Metabolic Profiling of Hematopoietic Stem Cells in Clonal Hematopoiesis (CHIP) NCT05246813 | Imelda Hospital, Bonheiden | — |
| Completed | Skeletal Response to Simulated Night Shift NCT05074277 | University of Colorado, Denver | N/A |
| Completed | Effect Of Whole Body Vibration Versus Weight Bearing Exercises On Osteoporosis In Breast Cancer Patients After NCT05970250 | Cairo University | N/A |
| Completed | The Optimal Sequential Therapy After Long Term Denosumab Treatment NCT05091099 | National Taiwan University Hospital | Phase 4 |
| Recruiting | Zoledronate Early to Hip Fracture Patients - Safe and Effective? NCT05025293 | Lene Bergendal Solberg | Phase 4 |
| Enrolling By Invitation | Quest to Analyze One Thousand Humans Meditating NCT06583395 | Tobias Moeller-Bertram | — |
| Completed | Chinese Osteoporotic Fracture Registration Network Platform NCT05339425 | Peking Union Medical College Hospital | — |
| Unknown | Assessment of TRACP-5b in Primary and Secondary Osteoporosis NCT05103592 | Assiut University | — |
| Active Not Recruiting | The Optimal Long Term Treatment Strategy of Anti-resorptive Medications NCT05091086 | National Taiwan University Hospital | Phase 4 |
| Active Not Recruiting | Treatment With Romosozumab Versus Denosumab to Improve Bone Mineral Density and Architecture in Subacute SCI NCT05101018 | James J. Peters Veterans Affairs Medical Center | Phase 4 |
| Completed | S-32 PG 242 Short Stem NCT05083728 | St. Louis Joint Replacement Institute | — |
| Active Not Recruiting | Skeletal Effects of Chronic Night Shift NCT05091021 | University of Colorado, Denver | — |
| Completed | A Study to Test the Efficacy, Safety and Tolerability of Romosozumab Treatment in Postmenopausal Chinese Women NCT05067335 | UCB Biopharma SRL | Phase 3 |
| Unknown | Effects of Denosumab on Bone Fusion in Osteoporotic Patients After Lumbar Fusion NCT05203588 | Shanghai Changzheng Hospital | Phase 4 |
| Completed | Exercise Mode and Acute Bone Resorption NCT04815824 | VA Office of Research and Development | N/A |
| Completed | Effects of OsteoStrong vs. Individually Adapted and Combined Training on Bone Health NCT05721014 | Karolinska Institutet | N/A |
| Completed | Analysis of Bone Quality in Adult Patients With Inflammatory Bowel Disease NCT05171153 | Quironsalud | — |
| Terminated | Increasing Bone Density by Application of Surface Electrical Stimulation NCT02734719 | University of Belgrade | N/A |
| Completed | Interest of Nutritional Care of Children With Sickle Cell Disease on Bone Mineral Density and Body Composition NCT04754711 | Centre Hospitalier Régional d'Orléans | N/A |
| Unknown | Comprehensive Risk Assessment and Prevention Plan of Osteoporosis and Sarcopenia for the Elderly Participating NCT05104034 | National Taiwan University Hospital | N/A |
| Completed | A Study of High-Dose Vit D Versus Standard of Care Vit D Supplementation NCT05016310 | Wake Forest University Health Sciences | N/A |
| Active Not Recruiting | Romosozumab Use to Build Skeletal Integrity NCT05058976 | Susan L. Greenspan | Phase 4 |
| Recruiting | Biobank for Inflammatory Chronic Diseases and Osteoporosis NCT05039216 | University Hospital, Toulouse | — |
| Recruiting | Bone Loss Prevention With Zoledronic Acid or Denosumab in Critically Ill Adults NCT04608630 | Australian and New Zealand Intensive Care Research Centre | Phase 2 |
| Active Not Recruiting | MR-based Characterization of Bone Marrow in Its Relevance to Skeletal Disease in Patients With Diabetes NCT04950283 | University Hospital Tuebingen | — |
| Recruiting | RECONFIRM - Study of AGN1 LOEP in Patients with Osteoporosis NCT05202678 | AgNovos Healthcare, LLC | N/A |
| Unknown | Phase IV Clinical Trial to Evaluate Efficacy and Safety of MASI BONE S (Alendronate Sodium Trihydrate) in Post NCT05387200 | Yonsei University | Phase 4 |
| Unknown | EFFECT OF FLOW RESTRICTION ON BONE QUALITY WITHIN A MULTICOMPONENT EXERCISE PROGRAM FOR OLDER WOMEN WITH OSTEO NCT04760145 | Universitat Internacional de Catalunya | N/A |
| Unknown | Determining Feasibility of a Model of Care for Secondary Fracture Prevention NCT04931602 | Aga Khan University | — |
| Unknown | Study and Follow-up of the Clinical Effectiveness and Comparative Safety of Biosimilar Teriparatide in the Man NCT05369013 | STADA, Spain | — |
| Completed | Effect of Oral Vitamin D3 and Calcium Supplementation on Muscle and Bone Health Among Rural Post-menopausal Wo NCT06900387 | Dr. Anuradha Khadilkar | N/A |
| Unknown | Effect of Fatty Liver Disease on Bone Density NCT04850547 | Sohag University | — |
| Unknown | A Study on Vertebral Bone Strength by Micro-CT-Like Image NCT04954417 | Peking University Third Hospital | — |
| Recruiting | RESTORE - Study of AGN1 LOEP to Prevent Secondary Hip Fractures NCT04796350 | AgNovos Healthcare, LLC | N/A |
| Unknown | Osteoporosis Treatment Protocol in Patients With Fragility Fractures: Application and Efficacy NCT04861142 | University General Hospital of Heraklion | — |
| Unknown | The Effect of Virtual Reality Exercises on Balance in Patients With Osteoporosis NCT04780997 | Nigde Omer Halisdemir University | N/A |
| Completed | Awareness Model in Prevention of Osteoporosis NCT06028243 | Ankara Yildirim Beyazıt University | N/A |
| Unknown | Identifying Risk Factors for Falls in Patients With a High Risk of Fracture Using Connected Insoles (FeetMe Mo NCT05155761 | FeetMe | N/A |
| Unknown | Hands-Up: Exercise and Education Program After a Wrist Fracture NCT03997682 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Recruiting | Sarcopenia, Fall and Osteoporosis in Chronic Kidney Disease NCT04515342 | Herlev Hospital | — |
| Unknown | Intervention Study of Drugs in Patients Osteopenia and Osteoporosis NCT04719572 | Chinese PLA General Hospital | N/A |
| Completed | Romosozumab in Women With Chronic SCI NCT04708886 | Northwestern University | Phase 2 |
| Recruiting | Health ImprOvement Program of Bone in China NCT05906147 | Second Xiangya Hospital of Central South University | — |
| Withdrawn | Influence of Verticalization on Bone Mineral Density and Biological Parameters of Bone Remodeling in Children NCT04761666 | Centre Hospitalier Universitaire, Amiens | — |
| Unknown | Pedicle Screw Fixation in Osteoporotic Lumbar Spine NCT04399421 | Peking University Third Hospital | — |
| Unknown | Changes in Weight, Body Composition and Metabolic Parameters After Discontinuing Dolutegravir or Tenofovir Dis NCT04903847 | Thomas Benfield | Phase 4 |
| Unknown | A Retrospective Comparison Between CPS and HC Techniques for Osteoporotic Fractures in the Thoracic or Lumbar NCT05130242 | Taipei Veterans General Hospital, Taiwan | — |
| Completed | Vitamin D Deficiency and Body Composition in the Patients With Hemophilia NCT05517070 | Tsung-Ying Li | — |
| Terminated | Effect of Vitamin K Supplementation on Circulating Levels of Osteocalcin on the Bone Metabolism and Aging NCT04669782 | University of Milano Bicocca | N/A |
| Unknown | Vitamin D Status and Bone Metabolism Status in Children With Congenital Epidermolysis Bullosa NCT05141838 | National Medical Research Center for Children's Health, Russian Federation | Phase 4 |
| Completed | Study to Evaluate and Compare the Bioequivalence of Two Abaloparatide-sMTS Treatments in Healthy Women. NCT04936984 | Radius Health, Inc. | Phase 1 |
| Recruiting | Image-guided Computational and Experimental Analyses of Fractured Patient's Bone (GAP) NCT04787679 | Laura Maria Vergani | — |
| Completed | Post-fracture Medication and Mortality NCT05366621 | National Cheng-Kung University Hospital | — |
| Completed | Healthy Bones, Healthy Life: Habitual Physical Activity on Bone & Metabolic Health in Pediatric Cancer Survivo NCT04472286 | University of Nebraska | — |
| Completed | Replication of the VERO Osteoporosis Trial in Healthcare Claims Data NCT04879420 | Brigham and Women's Hospital | — |
| Completed | Development of Cellular Models for Osteoblast Response Study to Adipocytic Secretions in an Osteoporosis Conte NCT04377880 | University Hospital, Lille | — |
| Completed | MoveStrong at Home: A Feasibility Study of a Model for Remote Delivery of Functional Strength and Balance Trai NCT04663685 | University of Waterloo | N/A |
| Completed | Replication of the HORIZON Pivotal Fracture Trial in Healthcare Claims Data NCT04736693 | Brigham and Women's Hospital | — |
| Active Not Recruiting | CONFIRM EXTENSION - Long-term Follow-up Study of Patients Treated with AGN1 LOEP NCT04511364 | AgNovos Healthcare, LLC | N/A |
| Completed | A Multiple Dose Study to Evaluate the Effect of SHR-1222 Injection in Postmenopausal Osteoporosis Patients NCT04435158 | Jiangsu HengRui Medicine Co., Ltd. | Phase 1 |
| Unknown | Osteoporosis and Haemophilia NCT04524481 | PD Dr. Andreas Strauß | — |
| Active Not Recruiting | Denosumab (DMAB) Discontinuation and Switching in Glucocorticoid-Induced Osteoporosis (GIOP): a Pilot Study NCT04177940 | University of Alabama at Birmingham | Phase 4 |
| Unknown | Evaluation of Clinical and Bone Density Improvement After Implantation of Allogenic Mesenchymal Stem Cell From NCT04501354 | Ahmad Jabir Rahyussalim | Phase 2 |
| Completed | The Postprandial Calcium Absorption of a Milk Derived Calcium Permeate - RENEW Acute Study NCT04550078 | Inge Tetens | N/A |
| Withdrawn | A Study to Evaluate Efficacy and Safety of Denosumab for Prevention and Treatment of Osteoporosis in 1st Time NCT04231682 | Albert Einstein Healthcare Network | Phase 2 |
| Completed | Effects of COVID-19 Induced Deconditioning After Long-term High Intensity Resistance Exercise NCT04444661 | University of Erlangen-Nürnberg Medical School | — |
| Withdrawn | Liver Transplantation: Skeletal Effects NCT03399227 | Medical University of Vienna | — |
| Completed | Psychological Impact of Quarantine in Osteoporosis Patient During COVID-19 Outbreak NCT04351633 | University Hospital, Lille | — |
| Terminated | The Role of Incretins in Bone Remodeling in Humans NCT03966261 | University Hospital, Angers | — |
| Completed | Exploring Efficacy, Cost Effectiveness and Experiences Related to Adherence of Different Bisphosphonate Regime NCT04283786 | Nottingham University Hospitals NHS Trust | — |
| Withdrawn | Study of a Bone Assessment Technique, Bone Mineral Analyser, Concerning the Prediction of Improvement in Bone NCT04253340 | University Hospital, Rouen | N/A |
| Completed | Prevalence of Osteosarcopenic Obesity in Older Adults NCT04288401 | Istanbul Medeniyet University | — |
| Unknown | Efficacy of Cone Beam Computed Tomography in Diagnosing Osteoporosis NCT04365504 | Postgraduate Institute of Dental Sciences Rohtak | — |
| Terminated | Validation of the Turkish Version of QUALEFFO-31 NCT04259099 | Bugra Ince | — |
| Unknown | A Physical Activity Program for Female Nursing Home Residents at Risk of Osteoporosis NCT04168658 | Chengdu Jinjiang Maternity and Child Health Hospital | N/A |
| Completed | Effect of Soluble Corn Fiber Supplementation for 1 Year on Bone Metabolism in Adolescents NCT02916862 | Florida International University | Phase 2 |
| Completed | Bone-biomarkers of Spinal Cord Injury Patients NCT04403256 | Yeungnam University Hospital | — |
| Terminated | The Effects of 12-months of Denosumab on Bone Density in Prevalent Kidney Transplant Recipients NCT03960554 | Thomas Nickolas, MD MS | Phase 2 |
| Unknown | 3D-printed Porous Titanium Alloy Cages Versus PEEK Cages in Patients With Osteoporosis NCT04086784 | Peking University Third Hospital | — |
| Completed | Determinants of Bone and Muscle Quality and Strength in Obesity With and Without Diabetes NCT04093856 | Suzanne Morin | — |
| Completed | Abaloparatide Before Total Knee Arthroplasty NCT04167163 | University of Wisconsin, Madison | Phase 4 |
| Terminated | Bone Response to Exercise in Women on Antiresorptive Medications NCT04275011 | University of Waterloo | N/A |
| Completed | Performance of CT Parameters Compared to Bone Mineral Density to Detect Bone Fragility in Rheumatoid Arthritis NCT04413448 | Central Hospital, Nancy, France | — |
| Withdrawn | Knee Osteoarthritis Outcome Measures in Arthritic Patients With Osteoporosis NCT03217513 | Edward Fox | — |
| Completed | Denosumab in Treating Patients With Bone Loss Due to Donor Stem Cell Transplant NCT03925532 | Roswell Park Cancer Institute | Phase 2 |
| Completed | Endocrine, Bone And Metabolic Disorders In Adults After Allogeneic Stem-cell Transplant NCT04488432 | University Hospital, Brest | — |
| Active Not Recruiting | Trial of Parkinson's And Zoledronic Acid NCT03924414 | California Pacific Medical Center Research Institute | Phase 4 |
| Completed | Nordic Walking for Individuals With Osteoporosis, Vertebral Fracture or Hyperkyphosis NCT03885466 | University of Saskatchewan | N/A |
| Completed | Effect of Sulfur Thermal Water on Circulating H2S Levels and Markers of Bone Metabolism in Osteopenic Subjects NCT06095349 | Istituto Ortopedico Rizzoli | N/A |
| Completed | DPP4-Inhibitors and Bone Metabolism in Diabetes NCT06770894 | Azienda Policlinico Umberto I | Phase 3 |
| Completed | The Effects of Bovine Colostrum in Bone Metabolism in Humans NCT04040010 | Petros Dinas | N/A |
| Completed | Models of Primary Osteoporosis Screening in Male Veterans NCT04079868 | VA Office of Research and Development | N/A |
| Withdrawn | Denosumab for Glucocorticoid-treated Children With Rheumatic Disorders NCT02418273 | Indiana University | Phase 1 / Phase 2 |
| Terminated | RCT of Vibration Effect on Vertebral BMD in Disabled Patients NCT04180267 | Chinese University of Hong Kong | N/A |
| Completed | Effects of Lagenbone on Bone Mineral Density NCT04557553 | Southern California University of Health Sciences | N/A |
| Unknown | Association of Cystatin C and Bone Mineral Density in Diabetic Patients. NCT04019938 | Fifth Affiliated Hospital, Sun Yat-Sen University | — |
| Completed | A Six-month Phase 2 Study of Oral hPTH(1-34) (EBP05) in Postmenopausal Women With Low Bone Mass NCT04003467 | Entera Bio Ltd. | Phase 2 |
| Unknown | Study of NaQuinate in Healthy Volunteers NCT04036617 | Haoma Medica Limited | Phase 1 |
| Unknown | Three Year Evaluation of a Cohort of Patients Presenting Osteoporotic Fractures NCT03994094 | Centre Hospitalier le Mans | — |
| Suspended | Vitamin D Status and Bone Health of Older Adults in Care Facilities NCT04399291 | University of Ulster | — |
| Completed | Is Osteoporosis Education Effective in Parkinsonian Patients NCT04536610 | Dokuz Eylul University | N/A |
| Completed | Nutrition Education to Promote Calcium Intake Among 30-65 Year-old Women in Vietnam NCT04196426 | Texas Tech University | N/A |
| Unknown | Osteoporosis in Primary Hyperparathyroidism NCT04085419 | University Medical Centre Ljubljana | Phase 4 |