Clinical Trials Directory

Trials / Sponsors / Shanghai Changzheng Hospital

Shanghai Changzheng Hospital

Academic / Other · 123 registered clinical trials56 currently recruiting.

StatusTrialPhaseStarted
Not Yet RecruitingThe Effect of Radiotherapy After Separation Surgery for Spinal Metastases
Spinal Metastases, Spinal Tumor, Radiotherapy
N/A2026-05-01
Not Yet RecruitingPostoperative Neurological Recovery and Risk Factor Analysis in Patients With Paralysis Due to Spinal Metastas
Metastatic Spinal Tumors, Spinal Cord Compression, Paralysis
2026-05-01
RecruitingMTS109 in Patients With Refractory Autoimmune Diseases
Systemic Lupus Erythematosus, Idiopathic Inflammatory Myopathies, Systemic Sclerosis (SSc)
EARLY_Phase 12026-03-24
RecruitingAnlotinib Combined With Sintilimab as First-line Treatment for Advanced Non-liver Metastatic Colorectal Cancer
Colorectal Cancer
Phase 22026-02-24
RecruitingA Study on the Correlation Between Tear Iron Levels and the Severity of Dry Eye Disease.
Dry Eye Disease, Iron
2026-02-06
Not Yet RecruitingSafety and Preliminary Efficacy Evaluation of LC-K76 Plus Anti-PD-1 Therapy in Patients With Metastatic Castra
mCRPC
EARLY_Phase 12026-02-01
Not Yet RecruitingSafety and Efficacy Evaluation of LC-K76 in Patients With Metastatic Hormone-Sensitive Prostate Cancer
mHSPC, mHNPC, Prostate Cancer Adenocarcinoma
EARLY_Phase 12026-02-01
RecruitingEye Tracking Study on Eye Movement Function and Visual Attention Patterns in Patients With Thyroid-Associated
Thyroid Associated Ophthalmopathies, Eye Tracking
2026-01-31
RecruitingEfficacy and Safety of Rifaximin-α in Treating MASLD
Metabolic Dysfunction-Associated Steatotic Liver Disease
EARLY_Phase 12026-01-15
Not Yet RecruitingApplication of Quantum Detection-Driven Artificial Intelligence Algorithms for Single-Molecule cfDNA Character
Benign Prostate Hypertrophy(BPH), Prostate Cancer (Diagnosis), Prostate Neoplasm
2025-12-01
Not Yet RecruitingObservational Study of Sacral Nerve Function After Sacral Tumor Resection
Sacral Tumors
2025-08-01
Not Yet RecruitingEvaluation of the Efficacy and Safety of Absorbable vs Traditional Bone Wax for Facet Fusion After Lumbar Fusi
Lumbar Fusion Surgery, Fusion of Joint
N/A2025-07-01
RecruitingCardiovascular-Kidney-Metabolic Syndrome in Shanghai Zicitizens
Metabolic Syndrome, Diabetes, Obesity and Overweight
2025-07-01
Not Yet RecruitingMSC303 Subcutaneous Injection for the Treatment of Immunologic Glomerular Disease.
Lupus Nephritis (LN), ANCA-Associated Glomerulonephritis
Phase 1 / Phase 22025-06-20
RecruitingA Dose-Expansion Trial of Intravenous HNF4α srRNA for Unresectable or Metastatic Colorectal Cancer
Colorectal Cancer Metastatic, Colorectal Cancer Recurrent, Colorectal Cancer Stage IV
EARLY_Phase 12025-06-10
RecruitingHiSCs in the Treatment of Rheumatoid Arthritis
Rheumatoid Arthritis (RA)
N/A2025-05-01
RecruitingEvaluation of the Efficacy and Safety Observation of IBI311 Treatment in Patients With Inactive TAO
Thyroid Associated Ophthalmopathies
Phase 42025-04-15
RecruitingEfficacy and Safety of Sequential Hormone Therapy and Tetuzumab Therapy in Patients With Moderate to Severe TA
Thyroid Associated Ophthalmopathies
Phase 42025-04-15
RecruitingThe Aim of This Study is to Assess the Efficacy and Safety of Chidamide, Regorafenib in Combination With Iparo
Advanced Colorectal Cancer in the Third-line Treatment and Beyond, pMMR/MSS Advanced Colorectal Cancer
Phase 22025-04-10
RecruitingThe Safety and Efficacy of Sequential Hormone Therapy and IBI311 Therapy in Patients With Active Moderate to S
Thyroid Associated Ophthalmopathies
Phase 42025-04-10
Not Yet RecruitingEfficacy and Safety of LC-Z300-01 on Proteinuria in Diabetic Patients
Diabetic Kidney Disease
N/A2025-04-01
Not Yet Recruiting5-MTHF Supplementation for Treatment of Type 1 Diabetes Patients
Type 1 Diabetes Mellitus
N/A2025-04-01
RecruitingA Study on the Changes of Glucose Metabolism and Exocrine Function in Patients With Chronic Pancreatitis
Chronic Pancreatitis Pancreatic Exocrine Insufficiency Blood Glucose
EARLY_Phase 12025-04-01
RecruitingClinical Study of Safety and Efficacy of Universal PSMA CAR- T in Refractory CRPC
Metastatic Prostate Cancer, Castration-resistant Prostate Cancer, Metastatic Castration-resistant Prostate Cancer
Phase 12025-03-27
Active Not RecruitingSafety and Efficacy Evaluation of Anti IGF-1R Monoclonal Antibody Combined With Anti-PD-1 Monoclonal Antibody
mCRPC
EARLY_Phase 12025-03-10
Not Yet RecruitingEfficacy and Safety of LC-Z300-01 in Chinese With Type 2 Diabetes
Diabetes, Type 2 Diabetes
Phase 2 / Phase 32025-03-01
Not Yet RecruitingThe Characteristics of Blood Glucose Profile and the Changes of Hormones in PPDM-C Population
Chronic Pancreatitis, Diabetes
2025-02-11
RecruitingPancreatic Cancer and Diabetes Mellitus
Pancreatic Cancer, Surgery, Diabetes Mellitus
2025-01-03
RecruitingUCMSCs Combined With Allogeneic Islet Transplantation for the Treatment of Diabetes
Diabetes
N/A2024-12-30
Recruitinga Study of CT0596 in Relapsed/Refractory Multiple Myeloma and Relapsed/Refractory Plasma Cell Leukemia
Relapsed/Refractory Multiple Myeloma, Relapsed/Refractory Plasma Cell Leukemia
EARLY_Phase 12024-12-11
Not Yet RecruitingCarvedilol and Alverine in Portal Hypertension
Hypertension, Portal
Phase 2 / Phase 32024-11-15
RecruitingA Clinical Trial Evaluating the Safety and Efficacy of Intravenous HNF4α SrRNA in Treating Metastatic CRC Pati
Metastatic Colorectal Cancer (mCRC)
EARLY_Phase 12024-11-12
RecruitingA Clinical Trial Evaluating the Safety and Efficacy of Intravenous HNF4α srRNA in Treating Advanced ICC Patien
Intrahepatic Cholangiocarcinoma
EARLY_Phase 12024-11-07
RecruitingA Clinical Trial Evaluating the Safety and Efficacy of Intravenous CD-801 in Treating Advanced HCC Patients
Advanced Hepatocellular Carcinoma
EARLY_Phase 12024-10-12
CompletedThe Application of Multimodal Artificial Intelligence Systems in Prostate Cancer Diagnosis and Prognosis Analy
Healthy People, Benign Prostatic Hyperplasia, Prostate Cancer
2024-10-10
RecruitingEstablishment of Multiparametric Prediction Models for Moderate to SevereThyroid Associated Ophthalmopathy
Thyroid Associated Ophthalmopathy
2024-10-09
Active Not RecruitingEndocrine and Exocrine Secretory Function Alterations After Moderately Severe and Severe Acute Pancreatitis
Acute Pancreatitis (AP), Diabetes Mellitus
2024-10-08
RecruitingAnti-CD70-CAR-T Cell Injection for the Treatment of Locally Advanced or Relapsed/Metastatic CD70+ Inoperable R
Renal Cell Carcinoma
EARLY_Phase 12024-09-06
RecruitingIrinotecan Hydrochloride Liposome Injection (Ⅱ) Combined with Fluorouracil, Folinic Acid, Vermofenib and Cetux
Colorectal Carcinoma
Phase 22024-09-01
WithdrawnThe Safety and Efficacy of CD-801 in Patients With Advanced Intrahepatic Cholangiocarcinoma
Intrahepatic Cholangiocarcinoma
EARLY_Phase 12024-08-28
RecruitingEfficacy and Safety of Rifaximin in Treating MAFLD
Metabolic-associated Fatty Liver Disease
EARLY_Phase 12024-08-10
RecruitingInhaled Mesenchymal Stem Cell-Derived Exosomes in the Treatment of Post-Infectious Cough: A Single-Center Rand
Post-Infectious Cough
Phase 1 / Phase 22024-07-16
RecruitingApplication of a Novel Biomarker Based on Plasma cfDNA Assay in the Early Diagnosis of Prostate Cancer
Prostate Cancer
2024-07-09
RecruitingStudy of CT071 Injection in High Risk Newly Diagnosed Multiple Myeloma
Multiple Myeloma
EARLY_Phase 12024-06-06
Not Yet RecruitingThe Efficacy and Safety of Alverine in the Treatment of Portal Hypertension in Patients With Liver Cirrhosis
Hypertension, Portal
Phase 2 / Phase 32024-06-01
RecruitingCapeOX Combined With Bevacizumab Plus Anti-PD1 Antibody as Neoadjuvant Therapy for Locally Recurrent Colorecta
Locally Recurrent Colorectal Cancer
Phase 22024-06-01
Not Yet RecruitingThe Safety and Efficacy of Alverine in the Treatment of Cirrhotic Portal Hypertension
Hypertension, Portal
Phase 2 / Phase 32024-06-01
RecruitingUCMSCs Combined With Standard Therapy for the Treatment of Newly Diagnosed Type 1 Diabetes
Newly Diagnosed Type 1 Diabetes Mellitus
N/A2024-05-23
RecruitingAnti-CD19-CD3E-CAR-T Cells in Relapsed/Refractory Autoimmune Disease
Systemic Lupus Erythematosus (SLE), Sjogren's Syndrome, Systemic Sclerosis
N/A2024-04-20
RecruitingClinical Study of Safety and Efficacy of Enhanced PSMA CAR- T in Refractory CRPC
Metastatic Castration-resistant Prostate Cancer, Castration-resistant Prostate Cancer
EARLY_Phase 12024-03-03
Not Yet RecruitingA Study of Surufatinib Combined With Serplulimab in the Treatment of Advanced Solid Tumors With Neuroendocrine
Advanced Solid Tumors With Neuroendocrine Differentiation
N/A2024-01-28
RecruitingExtraperitoneal SINgle-port rObotic-assisted Radical Prostatectomy (RARP) Versus Transperitoneal Multi-port RA
Prostate Adenocarcinoma, Localized Prostate Carcinoma
N/A2024-01-08
Not Yet RecruitingIntraoperative Radiotherapy in Treating Spinal Metastases
Spinal Metastases
N/A2024-01-01
RecruitingOral Prednisone in Treating LCH of Bone in Childhood and Adolescence
Langerhans Cell Histiocytosis of Bone
Phase 22023-11-04
UnknownThe Effect of Transcutaneous Electrical Acustimulation on Small Bowel Preparation for Capsule Endoscopy
Quality of Small Bowel Preparation
N/A2023-11-01
CompletedA Clinical Trial for the Safety and Efficacy of CD-801 in Patients With Advanced Hepatocellular Carcinoma
Advanced Hepatocellular Carcinoma
EARLY_Phase 12023-10-13
UnknownUtility of the Clamping Bean Test (CBT) for Covert Hepatic Encephalopathy Screening
Hepatic Encephalopathy, Covert Hepatic Encephalopathy
2023-10-09
UnknownThe Observation on the Efficacy of Dual Therapy Based on Vonoprazan in Eradicating Helicobacter Pylori
The Eradication Rate of Helicobacter Pylori
N/A2023-08-20
UnknownA Phase 2 Clinical Trial to Evaluate Zanubrutinib Combined With BR (Bendamustine/Rituximab) Regimen in Subject
Waldenström's Macroglobulinemia
Phase 22023-08-01
RecruitingEn Bloc Resection Versus Separation Surgery Combined With Radiotherapy for the Treatment of Spinal Oligometast
Spinal Metastases, Spinal Tumor, Radiotherapy
2023-07-01
UnknownStudy of FasT CAR-T GC012F Injection NDMM Patients
Multiple Myeloma
EARLY_Phase 12023-05-04
RecruitingCapeOX Combined With Bevacizumab Plus Anti-PD1 Antibody as Neoadjuvant Therapy for Microsatellite Stable Local
Locally Advanced Colorectal Cancer
Phase 22023-05-01
Active Not RecruitingStudy of CT071 Injection in RRMM or PPCL
Multiple Myeloma, Primary Plasma Cell Leukemia
EARLY_Phase 12023-04-28
UnknownTreating Donors With Intravenous Immunoglobulin to Reduce Donor-Derived Infections
Viremia, Bacteremia, Acute Rejection of Renal Transplant
Phase 42023-04-01
UnknownmNGS for Therapy of Urinary Infectious Diseases
Urinary Tract Infections, Sequelae of; Infection
2023-01-01
Enrolling By InvitationThe Instant Efficacy and Safety of Alverine in Decreasing Portal Hypertension: an Exploratory Pilot Study
Portal Hypertension
Phase 22022-10-28
UnknownPreoperative Nivolumab Plus Bevacizumab Combined With Chemotherapy Before Surgery in Patients With pMMR/MSS Co
Colorectal Cancer Liver Metastases
Phase 22022-10-01
UnknownRobotic Assisted Evacuation of Subacute and Chronic Supratentorial Deep Hypertensive Intracerebral Hemorrhage
Hypertensive Intracerebral Hemorrhage
N/A2022-09-01
UnknownTNFα Monoclonal Antibody for Acute Spinal Cord Injury
Spinal Cord Injuries
Phase 1 / Phase 22022-09-01
UnknownAnterior Spinal Canal Reconstruction and Fusion Surgery for Treating Degenerative Cervical Kyphosis With Steno
Degenerative Cervical Kyphosis With Stenosis
N/A2022-09-01
UnknownStudy of Dual Targeted CD19/BCMA FASTCART GC012F in Relapsed/ Refractory Multiple Myeloma
Multiple Myeloma
Phase 12022-06-13
UnknownAcute Hypertensive Cerebral Hemmorrhage Surgery
Hypertensive Intracerebral Hemorrhage
N/A2022-01-01
UnknownBCMA and CD19 Targeted Fast Dual CART for Chromosomal Abnomalities High-risk BCMA+ Multiple Myeloma
Multiple Myeloma
EARLY_Phase 12021-12-01
UnknownEffects of Denosumab on Bone Fusion in Osteoporotic Patients After Lumbar Fusion
Osteoporosis, Fusion of Spine, Lumbar Region
Phase 42021-10-09
RecruitingAllogeneic Regenerative Islet Transplantation for the Treatment of Brittle Type 1 Diabetes Mellitus
Brittle Type 1 Diabetes Mellitus
N/A2021-09-14
RecruitingMulti-centre Study to Evaluate ACAF Versus Laminoplasty in Treating Cervical Ossification of the Posterior Lon
Ossification of Posterior Longitudinal Ligament, Cervical Spondylosis With Myelopathy
N/A2021-08-17
UnknownStudy of FasT CAR-T GC012F Injection in High Risk TE NDMM Patients
Multiple Myeloma
Phase 1 / Phase 22021-06-28
UnknownArsenic Trioxide for Structural p53 Mutations
Arsenic Trioxide, p53 Mutations, Refractory Cancer
Phase 22021-01-01
UnknownAutologous Bone Marrow-derived Mononuclear Cells for Acute Spinal Cord Injury
Spinal Cord Injury
Phase 22020-10-01
CompletedQuantitative Assessment of Lumbar Facet Joint Degeneration, A Retrospective Study.
Facet Joint Pain; Low Back Pain, Facet Joints; Degeneration ; Deep Learning ;Artificial Intelligence, Facet Joint Disease
2020-09-01
CompletedAnlotinib Plus Sintilimab as First-line Treatment for Patients With Advanced Colorectal Cancer (APICAL-CRC)
Colorectal Cancer, Immunotherapy, Anlotinib
Phase 22020-06-01
RecruitingAnlotinib Plus Toripalimab as First-line Treatment for Advanced Gastric Cancer With ECOG 2 (APICAL-GC)
Gastric Cancer, Immunotherapy, Anlotinib
Phase 22020-02-10
UnknownBCMA and CD19 Targeted Fast Dual CAR-T for BCMA+ Refractory/Relapsed Multiple Myeloma
Multiple Myeloma
EARLY_Phase 12020-01-16
UnknownAutologous Platelet Rich Plasma on Low Back Pain
Low Back Pain
N/A2019-11-01
UnknownEvaluation of Ultrasensitive Chromosomal Aneuploidy Detection for Detecting Minimal Residual Disease in Multip
Multiple Myeloma
2019-10-20
UnknownAutologous Regenerative Islet Transplantation for Insulin-dependent Diabetes
Diabetes
N/A2019-09-30
UnknownEGFR Monoclonal Antibody for Advanced Gastric Cancer
Gastric Cancer, Cetuximab, Nimotuzumab
Phase 22019-07-01
UnknownPyrotinib in Combination With Trastuzumab in Treatment-refractory, HER2-positive Metastatic Colorectal Cancar.
Colorectal Cancer
N/A2019-07-01
UnknownAnlotinib in Advanced Solid Tumors With FGFR Alteration
Advanced Solid Tumor
N/A2019-07-01
UnknownRegorafenib Plus PD-1 Inhibitor in Patients With Colorectal Cancer
Colorectal Cancer, Immunotherapy
Phase 1 / Phase 22019-03-01
UnknownHigh-dose FOLFIRI in Advanced Colorectal Cancer Patients With Wild-type UGT1A1*6 and *28
Colorectal Cancer
Phase 22019-03-01
UnknownALK Inhibitor in Metastatic Colorectal Cancer With ALK Mutation.
Colorectal Cancer
N/A2019-03-01
UnknownCetuximab and Vemurafenib Plus FOLFIRI for BRAF V600E Mutated Advanced Colorectal Cancer (IMPROVEMENT)
Colorectal Cancer
Phase 22018-10-08
UnknownComputed Tomography Screening for Early Lung Cancer, COPD and Cardiovascular Disease in Shanghai, China
Lung Neoplasms, Mass Screening, Chronic Obstructive Pulmonary Disease
N/A2018-09-01
UnknownA Multi-center Study:Comparison of ACAF and ACCF in the Treatment of Cervical OPLL
Ossification of Posterior Longitudinal Ligament
N/A2018-01-01
UnknownEfficacy and Safety of Nerve Root Axial Decompression Surgery in The Treatment of Tethered Cord Syndrome
Tethered Cord Syndrome
N/A2017-06-16
UnknownWFA+M2BP in Evaluation of Portal Hypertension and Clinical Outcome in Patients With Liver Cirrhosis
Portal Hypertension, Cirrhosis
2017-06-01
UnknownComparison of ACAF and ACCF in the Treatment of Cervical OPLL
Ossification of Posterior Longitudinal Ligament
N/A2017-05-01
CompletedLow-dose Rifaximin in the Treatment of Covert Hepatic Encephalopathy
Covert Hepatic Encephalopathy
Phase 42017-05-01
CompletedPancreatic Surgery and Risk Factors
Pancreatic Surgey, Diabetes Mellitus
2017-01-01
CompletedEstablishment of Multimodal-multiparametric Progressive Prediction Models for Thyroid Associated Ophthalmopath
Thyroid-Associated Ophthalmopathy
2017-01-01
UnknownBenidipine and Hydrochlorothiazide in Fosinopril Treated Chronic Kidney Disease Patients With Hypertension
Chronic Kidney Disease
Phase 42016-02-01
UnknownSurvey and Reduction of Mortality in Peridialysis Uremic Patients Via Intervention of Risk Factors
End Stage Renal Disease on Dialysis
N/A2016-01-01
UnknownDiscovery and Validate of Multi-genetic Biomarkers for Capecitabine in Chinese Colorectal Patients
Colorectal Cancer, Capecitabine
2016-01-01
UnknownSystemic Redesign and Demonstration for Early Detection, Evaluation and Management of Chronic Kidney Disease i
Chronic Kidney Diseases
2015-10-01
UnknownDuration and Adverse Events of Non-cuffed Catheter in Patients With Hemodialysis
Renal Failure Chronic Requiring Hemodialysis, Central Venous Catheterization, Inadequate Hemodialysis Blood Flow
N/A2015-01-01
UnknownStenosis of Arteria-Venous Fistula in Maintenance Hemodialysis Patients: Early Intervention Trial
Uremia, Arteriovenous Fistula, Stenosis
N/A2015-01-01
UnknownTiming for Arteriovenous Fistula Creation and Its Effect on Target Organs in Patients With Chronic Renal Failu
Renal Failure, Chronic
N/A2015-01-01
UnknownVascular Access Choice and Outcomes in the Elderly and Very Elderly With End Stage Renal Disease in China
End Stage Renal Disease
N/A2014-10-01
UnknownRifaximin Reduces the Complications of Decompensated Cirrhosis: a Randomized Controlled Trial
Cirrhosis
Phase 42014-08-01
UnknownScreening for Early Lung Cancer in Shanghai, China
Lung Cancer
Phase 22014-07-01
UnknownTriptolide-Containing Formulation as Treatment for Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Phase 32014-04-01
UnknownRifaximin Predicts the Complications of Decompensated Cirrhosis
Cirrhosis
Phase 42013-10-01
CompletedHyperglycemia and Acute Pancreatitis
Acute Pancreatitis (AP), Diabetes Mellitus
2013-01-01
CompletedA Study of PAD Followed by Autologous Stem Cell Transplantation (ASCT) to Treat Newly Diagnosed Multiple Myelo
Multiple Myeloma
Phase 22012-12-01
CompletedEfficacy and Safety of Palonosetron Hydrochloride in the Prevention of Nausea and Vomiting
Neoplasms, Chemotherapy-Induced Nausea and Vomiting
Phase 42011-07-01
UnknownSingle-Operator Versus Dual-Operator Double-balloon Endoscopy in Patients With Small-Bowel Disorders
Small-Bowel Disorders
Phase 42010-08-01
UnknownDouble- Versus Single-balloon Enteroscopy for Obscure Small-bowel Bleeding
Small-Bowel Disorders
Phase 42010-07-01
UnknownSurgery for Traumatic Optic Neuropathy
Traumatic Optic Neuropathy
N/A2010-01-01
UnknownEntecavir for Patients With Decompensated Hepatitis B Virus (HBV)-Related Cirrhosis
Hepatitis B Virus, Decompensated Cirrhosis
Phase 42008-01-01
CompletedThe Effect of the Preoperative Oral Carbohydrate Attenuating Immediate Postoperative Insulin Resistance on PI3
Colorectal Disease
Phase 42006-11-01
CompletedA Clinical Trial of the Vessel Sealing System (LigaSure) in Azygoportal Disconnection and Splenectomy in Patie
Liver Cirrhosis
Phase 42006-01-01
UnknownCervical Laminoplasty Versus Laminectomy and Fusion: the Long-term Results Comparison
Myelopathy Cervical
2005-01-01