Trials / Not Yet Recruiting
Not Yet RecruitingNCT05812235
Bone Microstructure by Using HR-pQCT After Esophagectomy
Bone Microstructure by Using High-resolution Peripheral Quantitative Computed Tomography After Esophagectomy
- Status
- Not Yet Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 118 (estimated)
- Sponsor
- Nagasaki University · Academic / Other
- Sex
- Male
- Age
- 50 Years – 90 Years
- Healthy volunteers
- Accepted
Summary
Esophagectomy is most curative treatment to esophageal cancer. However, osteoporosis , which is characterized by both the loss of bone mass and the deterioration of bone architecture, is a serious complication in the long course after surgery. The aim of the present study was to evaluate osteoporosis by using high-resolution peripheral quantitative computed tomography (HR-pQCT) in the long course after esophagectomy. At least 3 years should have elapsed since operation without recurrence of esophageal cancer.
Detailed description
The patients after esophagectomy loss appetite and decrease the weight. Esophagectomy especially cause severe sarcopenia and metabolic change. Osteoporosis, which is characterized by both the loss of bone mass and the deterioration of bone architecture, is a serious complication in the long course after esophagectomy. The primary tools for assessing volumetric density and bone structure are quantitative computed tomography (QCT) and more recently, high-resolution peripheral quantitative computed tomography (HR-pQCT). However the validation of osteoporosis with HR-pQCT in the long course after esophagectomy remain elusive. The aim of the present study was to evaluate osteoporosis by using HR-pQCT in the long course after esophagectomy. At least 3 years should have elapsed since esophagectomy without any recurrence.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | esophagectomy | esophagectomy |
Timeline
- Start date
- 2023-05-25
- Primary completion
- 2026-03-01
- Completion
- 2027-03-31
- First posted
- 2023-04-13
- Last updated
- 2023-04-24
Source: ClinicalTrials.gov record NCT05812235. Inclusion in this directory is not an endorsement.