NCT06746649

Time-specific Exercise in Circadian Context

Healthy Aging: Effects of Time-specific Exercise on Functional, Structural, Metabolic and Immune Parameters in Circadian Context

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 34 (actual)
• Sponsor: Comenius University · Academic / Other
• Sex: All
• Age: 65 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The project aims to explore the mechanisms, by which physical activity can support healthy ageing and decrease the negative impact of ageing on the circadian system, musculoskeletal system and immunity.

Detailed description

The main aim of the project is to examine the effect of as well as of the three-month, timely specific training intervention on the functionality of circadian organization in elderly volunteers. The additive aim is to examine the effect of lifelong endurance physical activity, along with the experimental training intervention on the body composition, bone density, and selected hormonal, biochemical, histological and molecular indicators of metabolic health. Partial aims are as follows:n to explore the effect of morning and afternoon training on the most significant parameters, identified by the previous cross-sectional study, in sedentary elderly. Furthermore, to clarify adaptation mechanisms of experimental training protocol on selected parameters, that may explain possible differences in mechanisms of active and passive aging.

Conditions

• Osteopenia
• Osteoporosis
• Aging

Interventions

Type	Name	Description
PROCEDURE	Combined training	12-week long time specific combined training 2 times a week

Timeline

• Start date: 2024-02-01
• Primary completion: 2024-07-04
• Completion: 2025-03-30
• First posted: 2024-12-24
• Last updated: 2024-12-24

Locations

1 site across 1 country: Slovakia