| Not Yet Recruiting | Sonication-based OCD Neurosurgical Intervention Via Capsulotomy NCT06131502 | Brigham and Women's Hospital | Phase 1 / Phase 2 |
| Not Yet Recruiting | Neural Mechanisms of the Sensorymotor Circuit in Sensory Phenomena in OCD NCT07480408 | Shanghai Mental Health Center | N/A |
| Not Yet Recruiting | tDCS and Symptom Provocation in Treatment-Resistant OCD NCT07429500 | Centre Hospitalier Henri Laborit | N/A |
| Recruiting | The STEP-MIED Trial: Digital Stepped-Care for Emotional Disorders NCT07458100 | Peking University | N/A |
| Not Yet Recruiting | Locating Biomarkers in OCD Through Behavioral Tasks NCT03313622 | Baylor College of Medicine | — |
| Not Yet Recruiting | Assessments of Obsessive-compulsive Symptoms in Patients With Substances Use Disorder NCT07395453 | Assiut University | — |
| Recruiting | Psilocybin Whole Mushroom for the Treatment of Obsessive-compulsive Disorder. NCT07347405 | Francisco A Moreno | Phase 1 |
| Active Not Recruiting | Efficacy and Underlying Mechanisms of Group-Based Natural Psychotherapy for Anxiety Disorder NCT07518264 | Beijing HuiLongGuan Hospital | N/A |
| Not Yet Recruiting | Deep Brain Stimulation for Refractory Obsessive-Compulsive Disorder NCT06660225 | Nader Pouratian | N/A |
| Not Yet Recruiting | Valbenazine in Obsessive Compulsive Disorder NCT07111988 | University of Chicago | Phase 2 |
| Recruiting | Pilot Study of RR-HNK in OCD NCT06575075 | Carolyn Rodriguez | Phase 1 / Phase 2 |
| Not Yet Recruiting | Deep Brain Stimulation of the Anterior Cingulate Bundle (ACB) and the Ventral Anterior Limb of the Internal Ca NCT07303946 | Rhode Island Hospital | N/A |
| Not Yet Recruiting | Psilocybin for Treatment of OCD-2 NCT06992999 | Francisco A Moreno | Phase 1 / Phase 2 |
| Not Yet Recruiting | The Effect of Immersive Virtual Reality Treatment With Cognitive Behaviour Therapy for Obsessive-Compulsive Di NCT04534907 | Shanghai Mental Health Center | N/A |
| Recruiting | Transcranial Magnetic Stimulation and Psychotherapy for Treating Obsessive-Compulsive Disorder NCT07146438 | Adam Frank | N/A |
| Not Yet Recruiting | Feasibility and Efficacy Trial of a Culturally Adapted Guided Self-Help CBT Manual for OCD NCT07239401 | Pakistan Association of Cognitive Therapists | N/A |
| Not Yet Recruiting | Project EMPOWER-OCD NCT07158801 | Boston University Charles River Campus | Phase 1 |
| Recruiting | MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study) NCT05783817 | Carolyn Rodriguez | Phase 2 |
| Recruiting | Recovery in Telling Life Stories NCT07082777 | University of Aarhus | N/A |
| Recruiting | Precision Analytic Research Methods in OCD NCT07011901 | Icahn School of Medicine at Mount Sinai | N/A |
| Recruiting | Accelerated rTMS Therapeutic Approach for Refractory Obsessive-Compulsive Disorder NCT07198594 | Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University | N/A |
| Active Not Recruiting | The Combination of Pharmacotherapy and Cognitive Behavioral Psychotherapy Under the Recovery Perspective. NCT06993662 | Rakitzi, Stavroula | Phase 1 |
| Recruiting | Treating Adolescent Obsessive Compulsive Disorder With Transcranial Magnetic Stimulation NCT07065669 | University of California, San Francisco | N/A |
| Recruiting | Accelerated rTMS in Hospitalized Patients With OCD: a Feasibility and Mechanistic Study NCT07135414 | University Hospital, Ghent | N/A |
| Not Yet Recruiting | Using Virtual Reality Before Transcranial Magnetic Stimulation for the Treatment of OCD NCT06442527 | Yale University | N/A |
| Recruiting | Effect of a Family-Based CBT Self-Help Intervention for Adolescents With OCD NCT06942494 | Shanghai Mental Health Center | N/A |
| Enrolling By Invitation | Psychopathology in Adolescence NCT07259109 | IRCCS Centro Neurolesi Bonino Pulejo | — |
| Recruiting | Retrospective Analyses of TrakStar Database NCT06917339 | Neuronetics | — |
| Recruiting | Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness NCT06376734 | Brigham and Women's Hospital | Phase 2 |
| Not Yet Recruiting | Implementation of Internet-Based Psychotherapy for OCD in Primary Health Care in Two Cities in the State of Sã NCT06658756 | University of Sao Paulo General Hospital | N/A |
| Active Not Recruiting | EEG Evaluation of CBT for Obsessive-Compulsive Disorder NCT07000812 | Uskudar University | N/A |
| Recruiting | Efficacy and Influencing Factors of ALIC-NAc Deep Brain Stimulation in Treatment-Refractory Obsessive-Compulsi NCT07031544 | Shanghai Mental Health Center | N/A |
| Recruiting | ICBT for OCD in Children With Autism NCT06582225 | Karolinska Institutet | N/A |
| Recruiting | Evaluating the Feasibility, Safety and Efficacy of Psychotherapy Assisted Psilocybin for Treatment of Severe O NCT04882839 | Beersheva Mental Health Center | Phase 2 |
| Completed | ERP Plus Improv Group Therapy for OCD (IMPROVE Study) NCT06265233 | Stanford University | N/A |
| Recruiting | Improving Obsessive-compulsive Disorder Treatments: from Lesions to Neuromodulation Targets NCT06490965 | Fundacao Champalimaud | N/A |
| Recruiting | Brief Culturally Adapted CBT for OCD NCT07232823 | Pakistan Association of Cognitive Therapists | N/A |
| Recruiting | Mechanisms of Exposure Therapy for OCD NCT06173752 | Mclean Hospital | N/A |
| Completed | Online Exposure Therapy for Obsessive-Compulsive Disorder (OCD) Study NCT06470893 | University of Miami | N/A |
| Active Not Recruiting | Targeted Circuit-Based Transcranial Focused Ultrasound Intervention for Obsessive-Compulsive Disorder TUS-OCD NCT06722339 | University of Plymouth | N/A |
| Recruiting | Concentrated Exposure and Response Prevention for Children With Obsessive-compulsive Disorder NCT06621381 | Uppsala University Hospital | N/A |
| Recruiting | Feasibility, Clinical Effects, and Safety of Psilocybin-assisted Psychotherapy for Treatment-resistant OCD NCT06299319 | Centre for Addiction and Mental Health | Phase 1 |
| Recruiting | Effect of the French Version If the Metagognitive Bibliotherapy Program "MYMCT" on Obsessive-compulsive Sympto NCT06494735 | Centre Hospitalier Universitaire de Nice | N/A |
| Enrolling By Invitation | Pathogenesis of Pediatric Obsessive-compulsive Disorder: Based on the Microbiota-gut-brain Axis NCT06754319 | Shanghai Mental Health Center | — |
| Recruiting | Safety and Efficacy of Pramipexole Treatment in Resistant Obsessive-Compulsive Disorder (OCD) NCT06611592 | Clinical Academic Center (2CA-Braga) | Phase 2 |
| Recruiting | Identifying Local Field Potential Biomarkers for Obsessive-compulsive Disorder Treatment With Deep Brain Stimu NCT06542224 | West China Hospital | N/A |
| Recruiting | A Multicenter Pediatric Deep Brain Stimulation Registry NCT06585618 | Boston Children's Hospital | — |
| Recruiting | Efficacy and Influencing Factors of Deep Transcranial Magnetic Stimulation in the Treatment of OCD NCT06692114 | Zhen Wang | N/A |
| Recruiting | Towards Remission and Full Recovery From Obsessive-compulsive Disorder NCT06318806 | Ciusss de L'Est de l'Île de Montréal | N/A |
| Recruiting | Metacognitive Therapy for Obsessive-Compulsive Disorder NCT06466057 | Northeast Normal University | N/A |
| Recruiting | Discovering Factors in the Clinical Study Journey of Patients With OCD NCT05881356 | Power Life Sciences Inc. | — |
| Recruiting | Personalized DBS for OCD Guided by Stereoencephalography Mapping NCT06347978 | Andrew Moses Lee, MD, PhD | N/A |
| Enrolling By Invitation | Unique Electroencephalography (EEG) Markers of Habit Behaviors in Obsessive-Compulsive Disorder (OCD) NCT06882902 | Shanghai Mental Health Center | N/A |
| Recruiting | Brief-intensive CBT Versus Once-weekly CBT in Anxiety-related Disorders NCT05942391 | Universitair Ziekenhuis Brussel | N/A |
| Recruiting | Using Personalized Assessments in the Treatment of Childhood OCD NCT06407648 | Johns Hopkins University | N/A |
| Unknown | Traditional Islamically Integrated Psychotherapy for Muslims With OCD in Pakistan NCT06302712 | International Islamic University Malaysia | N/A |
| Active Not Recruiting | TMS + Exposure Therapy for Pediatric OCD NCT05931913 | Bradley Hospital | N/A |
| Recruiting | Virtual Reality Exposure Therapy for Obsessive-Compulsive Disorder: Outpatients Trial NCT07206199 | National Institute of Mental Health, Czech Republic | N/A |
| Withdrawn | Pilot Study of CBT With tDCS for Adults Being Treated for Obsessive Compulsive Disorder NCT05964998 | Rogers Behavioral Health | N/A |
| Completed | esTOCma, an App Used by Teachers: an RCT NCT06334887 | University of Valencia | N/A |
| Recruiting | Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2) NCT05940324 | Stanford University | Phase 2 |
| Recruiting | An OCD Prevention Programme for at Risk Adults NCT06262464 | Babes-Bolyai University | N/A |
| Completed | Transcranial Direct Current Stimulation (tDCS) in Different Psychiatric Disorders NCT07452835 | Menoufia University | N/A |
| Active Not Recruiting | An Automated Navigation System for Deep Brain Electrode Implantation NCT06396494 | Beijing Tiantan Hospital | — |
| Active Not Recruiting | Effectiveness of a Self-guided Mobile Application in Improving Obsessive Compulsive Disorder Symptoms NCT06202677 | National University of Singapore | N/A |
| Unknown | Effectiveness of Accelerated Deep TMS in OCD NCT06177470 | Pamukkale University | N/A |
| Completed | HANDS-ON: a Personalized, Brief and Intensive Exposure-based Intervention for Youth With Persistent Anxiety or NCT06152913 | Accare | N/A |
| Recruiting | SPACE: a Parent-based Treatment for Pediatric OCD NCT06356090 | Chaim Huijser | N/A |
| Recruiting | tDCS Associated With Symptom Provocation in the Management of Patients With Resistant Obsessive Compulsive Dis NCT06017713 | Centre Hospitalier Henri Laborit | N/A |
| Unknown | A Precision Medicine Approach to Target Engagement for Emotion Regulation NCT05651295 | Matthew Southward | N/A |
| Recruiting | Accelerated Rotational Field Deep TMS for Treating OCD NCT07116785 | Ben-Gurion University of the Negev | N/A |
| Unknown | Effect on Obsessive-Compulsive Beliefs and Symptoms of MCT-OCD NCT06029738 | University of Gaziantep | N/A |
| Recruiting | Diagnostic Accuracy of the Stepped Screening Protocol and Its Screening Tools in the Perinatal Period. NCT05961306 | University Hospital, Ghent | — |
| Recruiting | Study on Therapeutic Mechanism of Natural Psychotherapy for Neurosis NCT06443125 | Xiang Yang Zhang | N/A |
| Unknown | pBFS Guided High-dose rTMS Therapy for Treatment-Resistant Obsessive-Compulsive Disorder NCT05964062 | Changping Laboratory | N/A |
| Active Not Recruiting | Effects of Repeated Psilocybin Dosing in OCD NCT05370911 | Yale University | Phase 1 |
| Unknown | pBFS Guided rTMS Therapy for Treatment-resistant Obsessive-Compulsive Disorder NCT05964049 | Changping Laboratory | N/A |
| Active Not Recruiting | A Clinical Trial of Tolcapone in Obsessive Compulsive Disorder NCT05624528 | University of Chicago | Phase 2 |
| Unknown | A Clinical Trial of Fecal Microbiota Transplantation in a Population With Obsessive-compulsive Disorder NCT05720793 | Valerie Taylor | Phase 2 |
| Recruiting | Neurostimulation Versus Therapy for Problems With Emotions NCT05712057 | Duke University | N/A |
| Recruiting | ITreatOCD: Predicting the Efficacy of Internet-based Cognitive Behavioral Therapy in Obsessive-compulsive Diso NCT05906069 | Pedro Morgado | N/A |
| Enrolling By Invitation | MODELING OBSESSIVE COMPULSIVE DISORDER AND EXPLORING TREATMENT RESPONSE USING INNOVATIVE THERAPIES AND STEM CE NCT07488663 | ASST Fatebenefratelli Sacco | N/A |
| Recruiting | Imagery Rescripting as a Stand-alone Treatment for OCD and BDD. NCT06346301 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Completed | Cognitive Flexibility and Response to TMS Therapy NCT06769243 | Gulhane Training and Research Hospital | N/A |
| Recruiting | SEEG-Guided DBS for OCD NCT05623306 | Katherine Scangos | N/A |
| Unknown | Art Therapy in an Intensive OCD Program NCT05855902 | Sunnybrook Health Sciences Centre | — |
| Unknown | Immersive Virtual Reality & Obsessive Compulsive Disorder NCT05841017 | Consorci Hospitalari de Vic | N/A |
| Unknown | Disgust Reduction Through Evaluative Conditioning (DREC) and tDCS in Contamination-Based OCD NCT05907369 | Ferdowsi University of Mashhad | N/A |
| Withdrawn | New Stereotactic Frame System for Neurosurgery NCT04283812 | Mayo Clinic | N/A |
| Recruiting | Neural Mechanisms of Response Inhibition Training for OCRD NCT05377125 | University of Wisconsin, Milwaukee | N/A |
| Recruiting | Neurosurgical Outcome Network NCT06724029 | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | — |
| Recruiting | CBT Augmentation to Promote Medication Discontinuation in Pediatric OCD NCT05609916 | Baylor College of Medicine | N/A |
| Active Not Recruiting | Effects of Psilocybin in Obsessive Compulsive Disorder NCT05546658 | Johns Hopkins University | EARLY_Phase 1 |
| Completed | dTMS in Obsessive Compulsive Disorder NCT06077370 | Pamukkale University | N/A |
| Enrolling By Invitation | Cognitive Rehabilitation and Exposure Therapy for Geriatric Hoarding NCT05254015 | University of California, San Diego | N/A |
| Unknown | Four-day Intensive Treatment Versus Standard Cognitive Behavioral Therapy for Adults With Obsessive-compulsive NCT05608278 | Karolinska Institutet | N/A |
| Recruiting | Virtual Reality Exposure Therapy for Obsessive-Compulsive Disorder: A Randomized Controlled Trial in Inpatient NCT07245134 | National Institute of Mental Health, Czech Republic | N/A |
| Recruiting | CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy NCT05467683 | University of Texas at Austin | N/A |
| Completed | PsilOCD: A Pharmacological-Challenge Feasibility Study NCT06258031 | Imperial College London | Phase 1 |
| Completed | Computerized Intervention Targeting the Error-Related Negativity and Balance N1 in Anxious Children NCT05503017 | Florida State University | N/A |
| Unknown | Function-metabolism Coupling in Decision-making Confidence Neural Network of Obsessive-compulsive Disorder NCT05563935 | Shanghai Mental Health Center | N/A |
| Recruiting | Ketamine in OCD: Efficacy and Effects on Stress and Cognition NCT05577585 | Medical University of Vienna | N/A |
| Recruiting | Developing Brain, Impulsivity and Compulsivity NCT04631042 | National Institute of Mental Health (NIMH) | — |
| Completed | Light Therapy for Obsessive-compulsive Disorder (OCD) NCT05391503 | University of Colorado, Boulder | N/A |
| Completed | Transcranial Direct Current Stimulation Potentiation of Fear Extinction in OCD NCT05521074 | Massachusetts General Hospital | N/A |
| Terminated | Effect of SC-ICBT for Adults With OCD:A Three-Arm Randomized Controlled Trial NCT05528224 | Shanghai Mental Health Center | N/A |
| Enrolling By Invitation | Ketamine Safety and Tolerability in Psychiatric Inpatient Care (KetGD) NCT05565352 | Medical University of Gdansk | — |
| Active Not Recruiting | Acceptance and Commitment Therapy (ACT) in Groups for Obsessive Compulsive Disorder: A Clinical Trial in Brazi NCT06548893 | Universidade Federal do Paraná | N/A |
| Active Not Recruiting | Imaging-Guided Low Intensity Focused Ultrasound (LIFU) NCT05467085 | Baylor College of Medicine | N/A |
| Unknown | Evaluation of the Long Term Efficacy and Durability of the BrainsWay Deep TMS in OCD Subjects NCT05404360 | Brainsway | N/A |
| Recruiting | Individually Targeted Neuromodulation for Contamination-based OCD NCT05048251 | Mclean Hospital | N/A |
| Enrolling By Invitation | Ventral Capsulotomy for Intractable OCD NCT05659082 | Butler Hospital | Phase 3 |
| Withdrawn | Efficacy of Treatment With Pramipexole or Risperidone in Patients With Refractory Obsessive-compulsive Disorde NCT05401019 | Clinical Academic Center (2CA-Braga) | Phase 2 |
| Unknown | Priming in Repetitive Transcranial Magnetic Stimulation in the Treatment of Obsessive Compulsive Disorder NCT06049706 | Suellen Andrade | N/A |
| Recruiting | Caloric Vestibular Stimulation for Modulation of Insight in Obsessive-Compulsive Spectrum Disorders NCT03918577 | Stanford University | N/A |
| Enrolling By Invitation | Rituximab Treatment for Psychosis And/or Obsessive Compulsive Disorder with Probable Immune System Involvement NCT04323566 | Uppsala University Hospital | Phase 2 |
| Recruiting | Study on the Efficacy Mechanism of Natural Psychotherapy for Neurosis NCT05552014 | Beijing HuiLongGuan Hospital | N/A |
| Completed | Epidiolex in Obsessive Compulsive Disorder and Related Disorders NCT04978428 | University of Chicago | Phase 2 |
| Recruiting | Glucose Consumption During Deep Brain Stimulation With Functional [18F]FDG-Brain-PET in Obsessive-Compulsive D NCT05577598 | Medical University of Vienna | N/A |
| Completed | TMS for Improving Response Inhibition in Adolescents With OCD NCT05104697 | Bradley Hospital | N/A |
| Recruiting | Interpretation Bias as a Mechanism of Treatment Response in OCD NCT05224414 | Mclean Hospital | N/A |
| Completed | Internet-Based, Parent-Led Cognitive-Behavioral Therapy for Anxiety in Youth With ASD NCT05284435 | Baylor College of Medicine | N/A |
| Active Not Recruiting | Individualized Neuroimaging Biomarkers for Predicting rTMS Response in OCD NCT05829681 | Stanford University | N/A |
| Active Not Recruiting | Transdiagnostic Versus Diagnosis-specific Cognitive-behavioral Therapy NCT05249543 | Karolinska Institutet | N/A |
| Withdrawn | Multimodal Assessment of Cannabinoid Target Engagement in Adults With Obsessive-Compulsive Disorder NCT04880278 | New York State Psychiatric Institute | Phase 1 / Phase 2 |
| Completed | Obsessions and Suicidality in Youth With Bipolar 1 Disorder NCT05878808 | Cairo University | — |
| Recruiting | Study of Dextromethorphan in OCD and Related Disorders NCT04899687 | Stanford University | Phase 2 |
| Completed | Relationship Between Repetitive Negative Thinking and CBT Outcomes NCT06370559 | South London and Maudsley NHS Foundation Trust | — |
| Completed | ESTOCMA: Mental Health Application for Enhancing Mental Health Literacy About Obsessive-compulsive Disorder NCT04777292 | University of Valencia | N/A |
| Completed | Neural Correlates of Compulsivity NCT05195476 | Columbia University | — |
| Unknown | iTBS-DCS in Obsessive Compulsive Disorder NCT05177601 | University of Calgary | Phase 2 |
| Recruiting | Neural Mechanisms of Obsessive-compulsive Disorder (OCD) Treatment Failure NCT05520398 | University College, London | — |
| Active Not Recruiting | Mindfulness-Based Interventions for OCD NCT04914923 | Sunnybrook Health Sciences Centre | N/A |
| Unknown | Psychiatric Comorbidity and Quality of Life in Patients With Obsessive Compulsive Disorder(Case Control Study NCT05105581 | Assiut University | — |
| Unknown | An ERP-based Mobile Intervention as an Adjunctive Treatment for OCD NCT05166707 | BIXINK Therapeutics Co., Ltd. | N/A |
| Recruiting | Deep Brain Stimulation Surgery for the Treatment of Refractory Obsessive-Compulsive Disorder NCT05995951 | Rabin Medical Center | N/A |
| Completed | Effects of an EMDR Intervention on Traumatic and Obsessive Symptoms NCT06110702 | University of Pisa | N/A |
| Completed | A Wearable AI Feedback Tool for Pediatric OCD NCT05064527 | Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital | — |
| Recruiting | Bilateral Lateral OFC rTMS in Obsessive Compulsive Disorder NCT04934007 | Centre Hospitalier Henri Laborit | N/A |
| Unknown | Memantine for Refractory OCD Patients NCT05015595 | University of Roma La Sapienza | Phase 3 |
| Recruiting | Cortical Stimulation to Treat Obsessive Compulsive Disorder NCT04958096 | Andrew Moses Lee, MD, PhD | N/A |
| Completed | Smart Sensory Technology in Psychotherapy for Pediatric OCD NCT05291611 | University Hospital Tuebingen | N/A |
| Completed | The Efficacy and Safety of ALIC/NAcc-DBS for Treatment-refractory OCD NCT04967560 | Shanghai Mental Health Center | N/A |
| Completed | Digital Health Interventions for Obsessive Compulsive Disorder (OCD) NCT04136626 | Massachusetts General Hospital | N/A |
| Active Not Recruiting | Phase II Adaptive Deep Brain Stimulation for Obsessive-Compulsive Disorder NCT04806516 | Baylor College of Medicine | N/A |
| Completed | Increasing Treatment Efficacy Using SMART Methods for Personalizing Care NCT04642898 | Shannon E. Sauer-Zavala | N/A |
| Recruiting | Evaluation of Primary Care Behavioral Health (PCBH) With the Addition of Self-help CBT - A Randomized Multicen NCT04900064 | Linnaeus University | N/A |
| Unknown | Adjunctive Celecoxib in Childhood-onset OCD Study NCT04673578 | University of British Columbia | Phase 2 |
| Active Not Recruiting | Brain Recordings in Patients Undergoing Deep Brain Stimulation (DBS) for Severe Obsessive-Compulsive Disorder NCT05915741 | Baylor College of Medicine | — |
| Completed | Improving Attentional and Cognitive Control in the Psychological Treatment of Intrusive Thoughts NCT04225624 | Massachusetts General Hospital | N/A |
| Recruiting | Efficacy of Nitrous Oxide in OCD: Pilot Study NCT03826693 | Stanford University | Phase 2 |
| Unknown | Intervention Through EMDR and CBT With Women Victim of Childhood Sexual Abuse. A Randomized Controlled Trial. NCT04813224 | Universidad Internacional de Valencia | N/A |
| Suspended | Neuroinflammation in Patients With OCD NCT04786548 | New York State Psychiatric Institute | Phase 2 |
| Terminated | Long-term Safety Study of Adjunctive Troriluzole in Subjects With Obsessive Compulsive Disorder NCT04708834 | Biohaven Pharmaceuticals, Inc. | Phase 3 |
| Unknown | Accelerated Continue Theta-burst Stimulation (acTBS)Treatment for Obsessive Compulsive Disease NCT05221632 | Anhui Medical University | N/A |
| Completed | Efficacy and Safety Study of Adjunctive Troriluzule in Obsessive Compulsive Disorder NCT04693351 | Biohaven Pharmaceuticals, Inc. | Phase 3 |
| Terminated | Transcranial Direct Current Stimulation (tDCS) in Pediatric Obsessive Compulsive Disorder (OCD) NCT04548609 | Massachusetts General Hospital | N/A |
| Unknown | ON/OFF Stimulation and Reward Motivation in Patients With Deep Brain Stimulators NCT01590862 | Massachusetts General Hospital | N/A |
| Unknown | Neuroimaging Biomarkers for Predicting rTMS Response in OCD NCT04286126 | Stanford University | N/A |
| Completed | Narrative Therapy for Treatment-Resistant Obsessive-Compulsive Disorder NCT04154085 | Sunnybrook Health Sciences Centre | N/A |
| Recruiting | Short and Intensive Treatment of Children and Adolescents With Obsessive-Compulsive Disorder NCT04730011 | Susanne Walitza | N/A |
| Completed | Using Online Delivered Therapy and Brain Imaging to Better Understand OCD NCT04630197 | Callum Stephenson | N/A |
| Completed | Theta Burst Stimulation Plus Habit Override Training for Compulsive Behaviors NCT04580043 | Rebecca Price | N/A |
| Completed | Efficacy and Safety Study of Adjunctive Troriluzole in Obsessive Compulsive Disorder NCT04641143 | Biohaven Pharmaceuticals, Inc. | Phase 3 |
| Unknown | The Use of Transcranial Ultrasound Treatment of Obsessive-Compulsive Disorder NCT04775875 | Neurological Associates of West Los Angeles | N/A |
| Completed | A Trial of Parent-coached Exposure Therapy for Children With Anxiety Disorders and OCD NCT05777161 | Mayo Clinic | N/A |
| Recruiting | University of Iowa Interventional Psychiatry Service Patient Registry NCT04480918 | Mark Niciu | — |
| Completed | Virtual Reality System for Anxiety and OCD NCT03636022 | Minnesota HealthSolutions | N/A |
| Recruiting | Efficacy of Augmentation of Cognitive Behavioral Therapy With Transcranial Direct Current Stimulation for Obse NCT04527302 | Shanghai Mental Health Center | N/A |
| Terminated | Trial of Naproxen Sodium for the Treatment of OCD in Children With PANDAS NCT04015596 | Massachusetts General Hospital | Phase 4 |
| Recruiting | Pragmatic Trial of Obsessive-compulsive Disorder NCT04539951 | Shanghai Mental Health Center | Phase 2 |
| Completed | Psychosocial, Behavioral, and Radiologic Changes Following Radiosurgery for Benign Neurologic Disease NCT04688554 | Vanderbilt University Medical Center | — |
| Completed | Radical Openness for Adolescents Pilot NCT05913557 | Washington University School of Medicine | EARLY_Phase 1 |
| Completed | Child and Adolescent OCD Outcomes From Exposure and Response Prevention Video Teletherapy Treatment NCT06466447 | NOCD | — |
| Withdrawn | Is There a New Gold Standard for the Treatment of Obsessive-Compulsive Disorder? NCT04436952 | University of Alberta | N/A |
| Completed | Electroencephalography (EEG) Predictors of Transcranial Direct Current Stimulation (tDCS) in Obsessive-Compuls NCT04426773 | Shanghai Mental Health Center | N/A |
| Unknown | EEG Results of Deep TMS in Patients With OCD NCT05188833 | Istanbul Medipol University Hospital | N/A |
| Recruiting | Evaluation Study: Obsessive-compulsive Disorders in Childhood and Young Adulthood NCT04723485 | Susanne Walitza | — |
| Completed | Sensory Symptoms in Tourette Syndrome and Obsessive-Compulsive Disorder NCT04335175 | Vanderbilt University Medical Center | — |
| Completed | Impact of COVID-19 on Mental Health of OCD Patients and live-in Family Members NCT05656456 | University Hospital, Ghent | — |
| Completed | Targeting Taboo Thoughts In Obsessive-Compulsive Disorder NCT04313439 | Karolinska Institutet | N/A |
| Withdrawn | A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Obsessive-Compulsive Disorder NCT04211402 | ProgenaBiome | — |
| Unknown | The Neurocircuitry of Relief During Avoidance Learning in Patients With Obsessive-compulsive Disorder NCT04685018 | KU Leuven | — |
| Unknown | The Efficacy and Mechanism of DBS in VIC and NAcc for Refractory OCD NCT04228744 | Ruijin Hospital | N/A |
| Withdrawn | The Cost of Obsessive-compulsive Disorder (OCD) in China NCT04215549 | Shanghai Mental Health Center | — |
| Completed | Clinical Outcomes From NOCD Treatment of Obsessive-Compulsive Disorder Using Exposure and Response Prevention NCT04701372 | NOCD | — |
| Completed | Chart Review of Patients Undergoing Ketamine Infusions NCT04209296 | Brain and Cognition Discovery Foundation | — |
| Completed | Modulating Prefrontal Circuits Underlying Behavioral Flexibility in OCD: A TMS Study NCT04165577 | Butler Hospital | N/A |
| Completed | Transcranial Direct Current Stimulation (tDCS) in the Treatment of Drug-naïve Obsessive-compulsive Disorder(OC NCT04086446 | Shanghai Mental Health Center | N/A |
| Completed | Transdiagnostic Treatment Personalization NCT04584879 | Shannon E. Sauer-Zavala | N/A |
| Recruiting | Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD NCT04131829 | Yale University | Phase 1 / Phase 2 |
| Active Not Recruiting | Development of Adaptive Deep Brain Stimulation for OCD NCT04281134 | Baylor College of Medicine | N/A |
| Recruiting | Reinforcement Learning and Obsessive-compulsive Disorder: Exploring the Role of the Orbitofrontal Cortex NCT06566781 | Fundacao Champalimaud | — |
| Active Not Recruiting | Study of the Effectiveness of Transcranial Direct Current Stimulation on Obsessive Compulsive Disorder NCT04106102 | Centre Hospitalier Universitaire de Nice | N/A |
| Recruiting | Family Involvement in CBGT of OCD: a Randomized Controlled Trial NCT04071990 | University Hospital, Ghent | N/A |
| Unknown | Deep Brain Stimulation (DBS) for the Treatment of Refractory Obsessive-compulsive Disorder (OCD) NCT04217408 | Sunnybrook Health Sciences Centre | N/A |
| Completed | Rituximab for Obsessive-compulsive Disorder. (RITS-PO-2019) NCT03983031 | Region Örebro County | Phase 1 |
| Completed | Parent-Led Cognitive-Behavioral Teletherapy for Anxiety in Youth With ASD NCT04111874 | Baylor College of Medicine | N/A |
| Completed | Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Obsessive Compulsive Disorder NCT03649685 | Shanghai Mental Health Center | N/A |
| Completed | Exercising With Anxiety: Can Cognitive Behavioural Techniques Help People With Anxiety-related Disorders Exerc NCT04026152 | University of Regina | N/A |
| Suspended | A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease NCT04031469 | ProgenaBiome | — |
| Completed | Clinical and Electrophysiological Outcomes of tDCS in Patients With Treatment Resistant OCD NCT05595421 | Tri-Service General Hospital | N/A |
| Withdrawn | Waitlist-Control Trial of Smartphone CBT for Obsessive-Compulsive Disorder (OCD) NCT03767491 | Massachusetts General Hospital | N/A |
| Completed | Definitive Selection of Neuroimaging Biomarkers in Anxiety Disorder and Obsessive-compulsive Disorder: A Longi NCT03894085 | Central South University | N/A |
| Unknown | TMS-induced Plasticity Improving Cognitive Control in OCD NCT03667807 | Amsterdam UMC, location VUmc | N/A |
| Completed | Neurostimulation and OCD, a MRI Study NCT03918837 | Hospital Center Guillaume Régnier | N/A |
| Unknown | Evaluating the Effects of a Computerized Training Program Coupled With Cognitive Behavioral Therapy (CBT) for NCT03855943 | Hebrew University of Jerusalem | N/A |
| Unknown | Neurofeedback for Treatment-resistant Obsessive-compulsive Disorder (OCD) NCT03956771 | Pedro Morgado | N/A |
| Completed | Cognitive Bias Modification for OCD NCT03799419 | Mclean Hospital | N/A |
| Completed | Evaluating Unilateral Deep Brain Stimulation in Patients With Obsessive Compulsive Disorder NCT03894397 | KU Leuven | N/A |
| Terminated | School Withdrawal in Adolescents NCT03904784 | Centre Hospitalier Intercommunal Creteil | — |
| Completed | Alternative Treatment to Reduce Chronicity in OCD: Research Into Brain Response and Adequacy of Treatment NCT03929081 | GGZ Centraal | N/A |
| Completed | Towards Personalized Medicine for OCD NCT03852186 | Rigshospitalet, Denmark | N/A |
| Active Not Recruiting | Combined Cortical/Subcortical Recording and Stimulation as a Circuit-Oriented Treatment for Obsessive-Compulsi NCT03184454 | Massachusetts General Hospital | N/A |
| Completed | Stepped-Care Cognitive-Behavioral Treatment for Youth With ASD and Anxiety NCT03720795 | Baylor College of Medicine | N/A |
| Completed | Efficacy of Targeted Memory Reactivation for Enhancing Exposure Therapy NCT04663672 | University of Texas at Austin | N/A |
| Unknown | Enhancing the Acceptability of Psychological Treatments for Obsessive-compulsive Disorder NCT03661905 | Concordia University, Montreal | N/A |
| Recruiting | Pharmacogenetics of Antidepressant-Induced Disinhibition NCT03953014 | University of Calgary | — |
| Completed | Microbiome in Obsessive-compulsive Disorder NCT03638791 | Karolinska Institutet | — |
| Completed | Efficacy of Psilocybin in OCD: a Double-Blind, Placebo-Controlled Study. NCT03356483 | Yale University | Phase 1 |
| Completed | Randomized Controlled Trial of Standard ERP and OC-Go NCT03601312 | University of California, Los Angeles | N/A |
| Completed | Predicting Treatment Response in Patients With OCD NCT03993535 | University of Sao Paulo | Phase 4 |
| Completed | SMART ERP for the Behavioral Treatment of Youth With Obsessive Compulsive Disorder (OCD) NCT03672565 | University of British Columbia | N/A |
| Recruiting | Deep Brain Stimulation for Obsessive-compulsive Disorder NCT06628752 | Umeå University | N/A |
| Active Not Recruiting | Inference-Based Cognitive Therapy Versus Exposure and Response Prevention for Obsessive-Compulsive Disorder NCT03677947 | Centre de Recherche de l'Institut Universitaire en santé Mentale de Montréal | N/A |
| Terminated | Probiotic Treatment in Adult Obsessive-Compulsive Disorder NCT02334644 | McMaster University | Phase 4 |
| Active Not Recruiting | Development of Adaptive Deep Brain Stimulation for OCD (Phase 1a) NCT03457675 | Baylor College of Medicine | N/A |
| Unknown | Improving Access to Child Anxiety Treatment NCT03528109 | Bradley Hospital | N/A |
| Active Not Recruiting | Measuring Automated Behavioral Observations & Vocal Expressions (ABOVE) NCT03459456 | Baylor College of Medicine | — |
| Completed | The Role of Cognitive Control in the Transdiagnostic Conceptualization of "Intrusive Thoughts" NCT03414619 | Massachusetts General Hospital | N/A |
| Completed | Neurobiology of Sensory Phenomena in Obsessive-Compulsive Disorder NCT03451409 | NYU Langone Health | — |
| Completed | Decision-making Impairments in OCD: An Integrated Behavioral Economics Model NCT03420495 | Massachusetts General Hospital | N/A |
| Completed | Computerized Training for Individuals Diagnosed With Obsessive-Compulsive and Related Disorders NCT03182075 | Stanford University | N/A |
| Completed | Bioequivalence Study of Paroxetine Tablets and Paxil® Under Fasting and Fed Conditions in Chinese Healthy Volu NCT03504475 | Beijing Tongren Hospital | Phase 1 |
| Recruiting | Neurobiological Markers of Treatment Response for Anxiety and OCD NCT05663489 | Haukeland University Hospital | — |
| Completed | Tolcapone in Obsessive Compulsive Disorder NCT03348930 | University of Chicago | Phase 2 / Phase 3 |
| Completed | An eHealth Intervention for Obsessive Compulsive Disorder in Youth With Autism Spectrum Disorder NCT03473080 | Karolinska Institutet | N/A |
| Unknown | Deep Brain Stimulation of the Bilateral Habenula for Treatment-Refractory Obsessive-Compulsive Disorder NCT03463590 | Ruijin Hospital | N/A |
| Completed | Collabri Flex - Effect of Collaborative Care for People With Anxiety Disorders in General Practice NCT03113175 | Amager Hospital | N/A |
| Unknown | Mindfulness-Based Cognitive Therapy: Efficacy and fMRI-based Response Predictors in a Group of OCD Patients NCT03128749 | Corporacion Parc Tauli | N/A |
| Terminated | Cognitive Checking Intervention for Maladaptive Beliefs About Memory NCT03241056 | University of Manitoba | N/A |
| Completed | Troriluzole (BHV-4157) in Adult Participants With Obsessive Compulsive Disorder NCT03299166 | Biohaven Pharmaceuticals, Inc. | Phase 2 / Phase 3 |
| Completed | tDCS for Treatment Resistant Obsessive Compulsive Disorder NCT03304600 | Centre Hospitalier Henri Laborit | N/A |
| Completed | Internet-delivered CBT for Paediatric OCD NCT03263546 | Karolinska Institutet | N/A |
| Completed | Effects of Marijuana on Symptoms of OCD NCT03274440 | New York State Psychiatric Institute | Phase 1 / Phase 2 |
| Withdrawn | Patient-specific, Effective, and Rational Functional Connectivity Targeting for DBS in OCD NCT03244852 | Massachusetts General Hospital | — |
| Completed | Theta Burst Stimulation for Compulsive Behavior Non-invasive Brain Stimulation Study NCT03265015 | University of Pittsburgh | N/A |
| Withdrawn | Acceptance and Commitment Therapy in SSRI-Resistant Obsessive Compulsive Disorder NCT02955654 | Shanghai Mental Health Center | N/A |
| Unknown | Pharmacogenetics in Primary Care Psychotropics NCT03232502 | University of Arizona | Phase 3 |
| Unknown | Cognitive Behavioral Group Treatment for Obsessive-compulsive Disorder in Youth NCT04891367 | Aarhus University Hospital | N/A |
| Completed | Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment for Obsessive Compulsive Disease NCT03393078 | Anhui Medical University | N/A |
| Completed | Virtual Reality System to Increase Access to Exposure Therapy for Anxiety and OCD NCT02713516 | Mayo Clinic | N/A |
| Completed | The Modular Protocol for Mental Health (MPMH) NCT03143634 | Medical Research Council Cognition and Brain Sciences Unit | Phase 1 / Phase 2 |
| Completed | Effects of Ondansetron in Obsessive-compulsive and Tic Disorders NCT03239210 | NYU Langone Health | Phase 4 |
| Unknown | Psycho-education Intervention for Postpartum OCD and it's Influence on Symptom Severity and Treatment Self Ref NCT03172728 | Tel-Aviv Sourasky Medical Center | N/A |
| Unknown | Effects of Transcranial Direct Current Stimulation (tDCS) on Individuals With Prader-Willi Syndrome NCT03324906 | Federal University of São Paulo | N/A |
| Completed | Initial Development and Dissemination of OC-Go NCT03126305 | University of California, Los Angeles | — |
| Completed | Trial of MR-guided Focused Ultrasound (MRgFUS) Bilateral Capsulotomy for the Treatment of Refractory Obsessive NCT03156335 | Sunnybrook Health Sciences Centre | N/A |
| Completed | Mindfulness Meditation Utilizing an EEG Biofeedback Device for the Treatment for Obsessive Compulsive Disorder NCT03273699 | Sunnybrook Health Sciences Centre | N/A |
| Unknown | rTMS Over the Supplementary Motor Area for Treatment-resistant Obsessive-compulsive Disorder. NCT03211221 | CNS Onlus | Phase 1 / Phase 2 |
| Completed | The Study of Mindfulness Based Cognitive Therapy and Obsessive-Compulsive Disorder NCT03179839 | Shanghai Mental Health Center | N/A |
| Completed | Unified Protocol for Adolescents (UP-A) Change Processes NCT03102008 | University of Miami | N/A |
| Completed | Fear Conditioned Response in Healthy Subjects and in OCD Patients Pre and Post Treatment With Sertraline. NCT03068429 | University of Sao Paulo | Phase 4 |
| Unknown | The Safety and Efficacy of Long-term Treatment of PINS Stimulator System for Patients With Obsessive-Compulsiv NCT02253472 | Beijing Pins Medical Co., Ltd | EARLY_Phase 1 |
| Completed | Dealing With Intrusive Thoughts in OCD - a Comparison of Detached Mindfulness and Cognitive Restructuring NCT03002753 | Christoph-Dornier-Stiftung für Klinische Psychologie | N/A |
| Unknown | Exposure and Response Prevention Therapy for Obsessive-compulsive Disorder NCT02602886 | Ruijin Hospital | N/A |
| Terminated | Repetitive Transcranial Magnetic Stimulation (rTMS) for Obsessive-Compulsive Disorder (OCD) NCT02904356 | Columbia University | N/A |
| Completed | BIP in Jämtland Härjedalen: Increased Access to CBT Within Regular Health Care in Northern Sweden NCT02926365 | Karolinska Institutet | N/A |
| Recruiting | European Study of Quality of Life in Resistant OCD Patients Treated by STN DBS NCT02844049 | University Hospital, Grenoble | N/A |
| Completed | Integrating Pharmacogenomic Testing Into a Child Psychiatry Clinic NCT02855580 | University of Florida | — |
| Terminated | What Are You Looking for? Psychometric and Experimental Analyses of Reassurance Seeking in Obsessive-compulsiv NCT02909660 | Concordia University, Montreal | N/A |
| Completed | Cannabinoid Medication for Adults With OCD NCT02911324 | New York State Psychiatric Institute | Phase 1 / Phase 2 |
| Withdrawn | rTMS in Treatment Refractory Obsessive-Compulsive Disorder NCT02450695 | McMaster University | N/A |
| Unknown | Inhibitory Control of the Mind : Neural Bases and Impact for Obsessive-compulsive Disorders NCT02850393 | University Hospital, Caen | N/A |
| Withdrawn | Brief Intervention for OCD Fears NCT02790710 | New York State Psychiatric Institute | Phase 4 |
| Active Not Recruiting | Understanding How Ketamine Brings About Rapid Improvement in OCD NCT02624596 | Stanford University | Phase 2 |
| Completed | Cognitive Bias Modification for Thought-Action Fusion NCT03921255 | University of Wisconsin, Milwaukee | N/A |
| Unknown | Internet-delivered Transdiagnostic Intervention for Anxiety and Depression NCT02739607 | West University of Timisoara | N/A |
| Completed | Transcranial Direct Current Stimulation (tDCS) for Treatment-Resistant Obsessive-Compulsive Disorder (FRONT) NCT02743715 | University of Sao Paulo | N/A |
| Terminated | Cognitive Training in Obsessive Compulsive Disorder NCT02818088 | University of Stellenbosch | N/A |
| Completed | Internet-based Cognitive-behavior Therapy for Children With Obsessive-compulsive Disorder NCT02663167 | Karolinska Institutet | N/A |
| Terminated | Tapering Off Antidepressants NCT02661828 | Emory University | N/A |
| Unknown | Deep Brain Stimulation of NAc/ALIC to Prevent Treatment-Refractory Obsessive Compulsive Disorder NCT02601677 | Tang-Du Hospital | N/A |
| Completed | Translational Approach to the Understanding and Treatment of Obsessive-Compulsive Disorder (OCD). Can D-Cyclos NCT02656342 | Haukeland University Hospital | Phase 4 |
| Unknown | Developing Computerised CBT for Adults With OCD NCT02398045 | Institute of Psychiatry, London | EARLY_Phase 1 |
| Unknown | Novel Deep Brain Stimulation in Ventral Capsule and Stratum for Refractory Obsessive-Compulsive Disorder NCT02590445 | Ruijin Hospital | Phase 2 / Phase 3 |
| Completed | Methods for Managing Intrusive Thoughts NCT03416504 | University of North Carolina, Chapel Hill | N/A |
| Completed | Enhancement of Therapeutic Learning in OCD Using tDCS NCT03572543 | Yale University | N/A |
| Completed | Internet-based vs Face-to-face Cognitive Behavioural Therapy for Obsessive-compulsive Disorder NCT02541968 | Karolinska Institutet | N/A |
| Recruiting | Psychiatric Neurosurgery (PNS) for Obsessive Compulsive Disorder (OCD): A Qualitative Analysis of Patient and NCT02537795 | Universitaire Ziekenhuizen KU Leuven | — |
| Completed | Internet Delivered CBT for OCD in Adolescents With ASD - A Clinical Case Series NCT02660099 | Karolinska Institutet | N/A |
| Completed | Neurofeedback for Obsessive-Compulsive Disorder (OCD) NCT02206945 | Yale University | N/A |
| Completed | Mindfulness for Parents of OCD-affected Children NCT03212703 | University of British Columbia | N/A |
| Unknown | Neurocircuitry of Obsessive-Compulsive Disorder: Modulation by Transcranial Magnetic Stimulation NCT02704117 | Butler Hospital | Phase 3 |
| Completed | Transcranial Magnetic Stimulation (TMS) in Obsessive Compulsive Disorder (OCD): Mechanisms and Biomarkers NCT02355002 | Massachusetts General Hospital | N/A |
| Unknown | Repetitive Transcranial Magnetic Stimulation in Obsessive Compulsive Disorder NCT02884674 | University Hospital, Grenoble | N/A |
| Unknown | Initial Severity and Antidepressant Efficacy for Anxiety Disorders: an Individual Patient Data Meta-analysis NCT02476136 | prof. Peter de Jonge | — |
| Unknown | Safety and Effectiveness of Capsulotomy in Refractory OCD NCT02375152 | Ruijin Hospital | Phase 2 / Phase 3 |
| Withdrawn | China Refractory Obsessive-Compulsive Disorder Deep Brain Stimulation Study NCT02398318 | Ruijin Hospital | Phase 2 / Phase 3 |
| Unknown | tDCS as an add-on Treatment in SSRI-resistant OCD NCT02407288 | Hôpital le Vinatier | N/A |