NCT03143634

The Modular Protocol for Mental Health (MPMH)

The Modular Protocol for Mental Health (MPMH): A Pilot Randomised Clinical Trial of a Transdiagnostic Psychological Treatment for Mood and Anxiety Disorders in Adults

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 43 (actual)
• Sponsor: Medical Research Council Cognition and Brain Sciences Unit · Other Government
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Currently, our best psychological treatments for anxiety and mood disorders only focus on individual diagnoses. So, there are separate treatments for Panic Disorder, or Depressive Disorder, or Social Anxiety, etc. These 'diagnosis-specific' treatments work well for people whose problems fit neatly into a single diagnosis. However, they work far less well for people with complex problems involving multiple diagnoses, and 50% of patients fail to respond well to these existing treatments. The purpose of this study is to test a new psychological treatment for anxiety and mood problems (the Modular Protocol for Mental Health \[MPMH\]). Instead of focusing on any single diagnosis, MPMH combines the best treatment techniques into 10 modules to target problems common across all of the different mood and anxiety diagnoses (e.g., intense emotions, negative thinking, upsetting memories, distressing habits). MPMH should therefore be a better treatment for the large numbers of individuals whose problems do not fit neatly into a single diagnosis and for whom any treatments targeting a single diagnosis would leave significant difficulties unaddressed.

Conditions

• Major Depressive Disorder
• Generalized Anxiety Disorder
• Posttraumatic Stress Disorder
• Social Anxiety Disorder
• Panic Disorder
• Agoraphobia
• Obsessive-Compulsive Disorder
• Illness Anxiety Disorder

Interventions

Type	Name	Description
BEHAVIORAL	The Modular Protocol for Mental Health	This intervention is based on evidence-based cognitive-behavioural approaches to psychological disorders and offers a flexible approach to treatment delivery that targets the maladaptive processes common to mood and anxiety disorders.
BEHAVIORAL	Treatment-as-usual	This intervention will consist of psychological therapies delivered by high-intensity therapists or clinical psychologists.

Timeline

• Start date: 2017-07-18
• Primary completion: 2020-07-31
• Completion: 2020-07-31
• First posted: 2017-05-08
• Last updated: 2020-09-29

Locations

1 site across 1 country: United Kingdom