| Suspended | Ketamine-assisted Psychotherapy for Adolescent PTSD (KAP) NCT06378528 | University of Wisconsin, Madison | EARLY_Phase 1 |
| Not Yet Recruiting | Increasing Treatment Access in Trauma Exposed Children: Developing an Adapted Step One Intervention (RCT) NCT07396974 | The University of Texas Health Science Center, Houston | N/A |
| Not Yet Recruiting | Focused Ultrasound for PTSD in Veterans NCT06820138 | VA Office of Research and Development | Phase 2 |
| Not Yet Recruiting | A Randomized Controlled Trial of a Web-Based Moral Elevation Intervention for Veterans With PTSD NCT06788678 | VA Office of Research and Development | N/A |
| Recruiting | Biomolecular Characteristics of Reminder-Focused Positive-Psychiatry NCT04529031 | University of California, Los Angeles | N/A |
| Not Yet Recruiting | Increasing Treatment Access in Trauma Exposed Children: Developing an Adapted Step One Intervention (Pilot) NCT07396935 | The University of Texas Health Science Center, Houston | N/A |
| Not Yet Recruiting | Improving Cognitive Rehabilitation Outcomes NCT07055633 | VA Office of Research and Development | N/A |
| Not Yet Recruiting | Self-Help Cognitive Processing Therapy (CPT)/Women Veterans Network (WoVeN) Study NCT07250061 | Boston University | N/A |
| Recruiting | CIH Stepped Care for Co-occurring Chronic Pain and PTSD NCT06219408 | University of Washington | N/A |
| Recruiting | Adaptive Decision-making And Personalized Treatment for PTSD (ADAPT-PTSD) NCT07176273 | The University of Texas Health Science Center at San Antonio | N/A |
| Not Yet Recruiting | Prolonged Exposure Therapy to Treat Posttraumatic Stress Disorder in Pregnant Patients NCT06670079 | University of Vermont | N/A |
| Recruiting | Psilocybin and Methylenedioxymethamphetamine (MDMA) for Post-traumatic Stress Disorder (PTSD) NCT06989957 | Johns Hopkins University | Phase 1 |
| Not Yet Recruiting | School-based Practices in Arts and Resilience for Kids NCT06945497 | Wayne State University | N/A |
| Recruiting | Exploring Efficacy of Multi-Mode Cognitive Processing Therapy (CPT) for PTSD NCT07105345 | Far Eastern Memorial Hospital | N/A |
| Not Yet Recruiting | Adaptation of Written Exposure Therapy in Substance Treatment NCT07108608 | Potomac Health Foundations | N/A |
| Recruiting | Ketamine, SGB and Combination Treatment for TBI NCT06608277 | Northwestern University | Phase 2 |
| Recruiting | Dose Optimization of MDMA-Assisted Therapy for PTSD NCT06418178 | Bronx VA Medical Center | Phase 2 |
| Withdrawn | Intervention Evaluation WEH (Women Who Have Experienced Homelessness) NCT06570525 | Rush University Medical Center | Phase 1 |
| Recruiting | Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Af NCT05624931 | Boston University Charles River Campus | N/A |
| Completed | Testing STAR and TexSTAR: A Video and Text Messaging Intervention NCT06456190 | University of Wisconsin, Madison | N/A |
| Completed | Adapting and Piloting Behavioral Activation for Veterans With Alcohol Use Disorder and Posttraumatic Stress Di NCT06249386 | RTI International | N/A |
| Recruiting | Depressive Symptoms After Cardiac Surgery NCT06706323 | Roland von Känel | — |
| Recruiting | Mobile Anger Reduction Intervention NCT06094933 | VA Office of Research and Development | N/A |
| Recruiting | Multicenter iTBS Neuromodulation for PTSD Treatment NCT06434766 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Active Not Recruiting | CBT vs. Supportive Texts for PTSD & Hazardous Drinking (Project Better Study 2) NCT06648395 | University of Washington | N/A |
| Active Not Recruiting | Adaption of the STAIR-NT Trauma Intervention for Polysubstance Populations NCT06307340 | NYU Langone Health | N/A |
| Not Yet Recruiting | Guided Internet-based Trauma-focused CBT Programme for Post-traumatic Stress Disorder 'Spring' NCT06475716 | Vilnius University | N/A |
| Withdrawn | Effects of CBD Oil on Memory Reconsolidation and Trauma-Related Symptoms NCT05892276 | University of Texas at Austin | N/A |
| Recruiting | Resilient Roots: Supporting Youth and Families NCT06535516 | University of Rochester | N/A |
| Active Not Recruiting | tAN for PTSD and OUD in Buprenorphine Therapy NCT06130501 | University of Cincinnati | N/A |
| Recruiting | Trauma Screening/Referral and Interpersonal Violence Prevention for Women with Substance Use Disorders NCT06608979 | Clemson University | N/A |
| Recruiting | Novel Telemedicine-Delivered Prolonged Exposure Therapy for Treating PTSD in Individuals With OUD NCT06288711 | University of Vermont | N/A |
| Recruiting | Multimodal Image Analysis and Guidance of Neuromodulation for Trauma-Related Symptoms NCT06449326 | University of New Mexico | N/A |
| Recruiting | A Mechanistic Trial of the Neurobiology of Extinction Learning and Intraparietal Sulcus Stimulation NCT06234969 | University of Pennsylvania | N/A |
| Recruiting | Brief-intensive CBT Versus Once-weekly CBT in Anxiety-related Disorders NCT05942391 | Universitair Ziekenhuis Brussel | N/A |
| Unknown | Investigating a Novel Sensory-based Program for Veterans With PTSD NCT05766241 | McMaster University | N/A |
| Recruiting | Integration of Cognitive Processing Therapy and Relapse Prevention for Alcohol Use Disorder and PTSD NCT05959434 | Texas A&M University | Phase 2 |
| Active Not Recruiting | Using Data Science To Center Patient Perspectives in Mechanism Discovery NCT06233968 | Cambridge Health Alliance | — |
| Completed | Writing Wrongs: Expressive Writing for Microaggressions NCT06276725 | Auburn University | N/A |
| Recruiting | Prolonged Exposure for Swedish Immigrants NCT06193161 | Karolinska Institutet | N/A |
| Recruiting | The Predictive Role of Immune-inflammatory Biomarkers and Their Interaction With the Oxytocin System in Trauma NCT06348472 | Shalvata Mental Health Center | — |
| Recruiting | Mitigating PTSD-CUD After Sexual Assault NCT05989841 | University of Nevada, Las Vegas | Phase 1 / Phase 2 |
| Recruiting | Efficacy of Internet-delivered Trauma-focused CBT for Young People With PTSD NCT06185244 | Karolinska Institutet | N/A |
| Recruiting | Advancing Couple and Family Alcohol Treatment Through Patient-Oriented Research and Mentorship NCT05786157 | Medical University of South Carolina | N/A |
| Recruiting | Trauma BPE Prolonged Exposure Therapy for Injured Individuals Admitted to a Level I Trauma Center NCT06210711 | Baylor Research Institute | N/A |
| Unknown | Effects of Games on Memory Reconsolidation and Trauma Symptoms NCT06129435 | University of Texas at Austin | N/A |
| Recruiting | Biomarkers in the Retina for Prognosticating Mental Health Treatments NCT06363968 | VA Puget Sound Health Care System | N/A |
| Unknown | Testing a Peer-led Trauma-focused Intervention for Significant Others of Those With BPD NCT06135090 | York University | Phase 1 |
| Completed | Clinical Trial to Preliminarily Assess the Safety and Feasibility of SAT-014, a Software for Alleviating Sympt NCT06439407 | S-Alpha Therapeutics, Inc. | N/A |
| Recruiting | Mechanisms Underlying the Efficacy of Prolonged Exposure NCT05663151 | VA Boston Healthcare System | N/A |
| Completed | An Efficient Treatment for Posttraumatic Injury for Firefighters NCT05950035 | Palo Alto Veterans Institute for Research | N/A |
| Unknown | CBITS - Treat Trauma in Child Welfare NCT06038357 | University Hospital Ulm | N/A |
| Completed | A Pilot Participatory Program Evaluation of a Virtual Trauma Support Program for Autistic Adults NCT05862467 | University of Wyoming | N/A |
| Recruiting | Testing a PTSD m-Health Intervention to Improve Alcohol Treatment Outcomes NCT05564663 | Michigan State University | N/A |
| Recruiting | Piloting Virtual Reality Environments to Treat PTSD in Healthcare Workers NCT04887116 | Weill Medical College of Cornell University | EARLY_Phase 1 |
| Unknown | A Precision Medicine Approach to Target Engagement for Emotion Regulation NCT05651295 | Matthew Southward | N/A |
| Recruiting | Enhancing Psychotherapy for Veterans and Service Members With PTSD and Anxiety NCT05843695 | Baylor College of Medicine | N/A |
| Recruiting | Intensive Multi-Couple Therapy for PTSD Versus Relationship Education in Military Couples NCT06047691 | Penn State University | N/A |
| Recruiting | Positive Processes and Transition to Health (PATH) NCT06093906 | Case Western Reserve University | N/A |
| Recruiting | Enhancing Week-long Psychological Treatment for PTSD With Ketamine NCT05737693 | Yale University | Phase 2 |
| Recruiting | Diagnostic Accuracy of the Stepped Screening Protocol and Its Screening Tools in the Perinatal Period. NCT05961306 | University Hospital, Ghent | — |
| Recruiting | Impact of Cognitive Behavioral Therapy on PTSD-CVD Link NCT06429293 | Massachusetts General Hospital | N/A |
| Completed | Emotional Regulation in People With Co-occurring Posttraumatic Stress Disorder and Substance Use Disorder NCT05531318 | King's College London | — |
| Recruiting | Repurposing Low-Dose Clonidine for PTSD in Veterans NCT04877093 | Wake Forest University Health Sciences | Phase 3 |
| Recruiting | Group Written Exposure Therapy for Posttraumatic Stress Disorder NCT05729789 | St. Joseph's Healthcare Hamilton | N/A |
| Recruiting | Brief Behavioral Treatment for Insomnia in Veterans With Posttraumatic Stress Disorder NCT05780177 | VA Office of Research and Development | N/A |
| Completed | Sensory Modulation Dysfunction and Posttraumatic Stress Disorder NCT05967962 | Tel Aviv University | N/A |
| Recruiting | Investigating Cardiac Health of Adults With Trauma NCT05700201 | Nova Southeastern University | N/A |
| Recruiting | Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder NCT05516277 | University of California, Los Angeles | N/A |
| Recruiting | The Effectiveness of CFT for Reducing Self-criticism in Patients with Complex PTSD: a Single-case Experimental NCT05791760 | University of Twente | N/A |
| Recruiting | Integrated CBT to Improve Functioning in Veterans With Anxiety and Substance Use NCT04871100 | VA Office of Research and Development | N/A |
| Completed | SibACCESS: Developing a Telehealth Intervention to Address Unmet Psychosocial Needs of Siblings of Children Wi NCT04889755 | Boston University Charles River Campus | N/A |
| Withdrawn | Assessing and Enhancing Social Support NCT05187156 | VA Office of Research and Development | N/A |
| Withdrawn | Telehealth-Massed Imaginal Exposure for PTSD NCT05450224 | Medical University of South Carolina | N/A |
| Withdrawn | Pimavanserin for Insomnia in Veterans With Posttraumatic Stress Disorder: Proof of Concept NCT04809116 | Baylor College of Medicine | Phase 4 |
| Unknown | Evaluation of a Rumination Intervention for Individuals With PTSD: A Case Series NCT05625126 | University of Oxford | N/A |
| Completed | Written Exposure in Substance Treatment NCT06296940 | Potomac Health Foundations | N/A |
| Terminated | GAMBIT Task With PTSD and Healthy Control Participants NCT05313334 | Icahn School of Medicine at Mount Sinai | N/A |
| Recruiting | Testing a Scalable Model of Care to Improve Patients Access to Mental Health Services After Traumatic Injury NCT05497115 | Medical University of South Carolina | N/A |
| Terminated | Using Wearable Technology to Detect Symptoms of Posttraumatic Stress Disorder NCT05534100 | Rush University Medical Center | — |
| Completed | Enhancing Cognitive Processing Therapy for Posttraumatic Stress Disorder Via Stellate Ganglion Block Treatment NCT05534126 | Rush University Medical Center | N/A |
| Completed | CBT Texts for PTSD & Hazardous Drinking (Project Better) NCT05372042 | University of Washington | N/A |
| Completed | Online Intervention to Promote Resilience to Traumatic Stress During Pregnancy NCT04992767 | University of Illinois at Chicago | N/A |
| Completed | Long-term Quality of Life and Prognostic Factors in Severe COVID-19 Patients and Their Relatives NCT05520047 | Centre Hospitalier Régional Metz-Thionville | — |
| Unknown | Cognitive Processing Therapy (CPT) for Posttraumatic Stress Disorder and Borderline Personality Disorder (PTSD NCT04230668 | Palo Alto University | N/A |
| Recruiting | Written Exposure Therapy for Veterans With SUD and PTSD NCT05327504 | VA Office of Research and Development | N/A |
| Recruiting | Respiratory Training in the Treatment of Transdiagnostic Pathological Anxiety NCT05427708 | University of Texas at Austin | N/A |
| Withdrawn | Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSD NCT04968938 | Lykos Therapeutics | Phase 2 |
| Recruiting | Evaluation of the PE Coach Mobile Application Among Veterans With PTSD NCT04959695 | VA Office of Research and Development | N/A |
| Completed | Tackling Intrusive Traumatic Memories After Childbirth NCT05381155 | Centre Hospitalier Universitaire Vaudois | N/A |
| Recruiting | Family Involvement in Treatment for PTSD (FIT-PTSD): A Brief, Feasible Method for Enhancing Outcomes, Retentio NCT05267665 | VA Office of Research and Development | N/A |
| Recruiting | Evaluation of Trauma Center-Based Intervention for Adolescent Traumatic Injury Survivors NCT05086757 | Medical University of South Carolina | N/A |
| Unknown | PFI Hazardous Drinkers With Subclinical PTSD NCT04836442 | University of Houston | N/A |
| Completed | NightWare and Cardiovascular Health in Adults With PTSD NCT05365607 | University of Colorado, Denver | N/A |
| Suspended | Treating Nightmares in Posttraumatic Stress Disorder With Clonidine and Doxazosin NCT05360953 | Charite University, Berlin, Germany | Phase 2 |
| Unknown | STAIR for Trauma and Emotion Dysregulation NCT05397613 | Stanford University | N/A |
| Recruiting | Efficacy of Reboxetine and Methylphenidate Treatment on Attentional, Sensory and Emotional Dysregulation in Ad NCT05133804 | University of Haifa | Phase 2 |
| Active Not Recruiting | A Comparison of Prolonged Exposure Therapy, Pharmacotherapy, and Their Combination for PTSD NCT04961190 | University of Pennsylvania | Phase 4 |
| Completed | Family Support Intervention in Intensive Care Units NCT05280691 | Rahel Naef | N/A |
| Completed | Enhancing Prolonged Exposure With Cannabidiol to Treat Posttraumatic Stress Disorder NCT05132699 | The University of Texas Health Science Center at San Antonio | Phase 1 / Phase 2 |
| Completed | Clinical Trial to Evaluate the Safety and Efficacy of MeRT Treatment in Post-Traumatic Stress Disorder NCT02990793 | Wave Neuroscience | N/A |
| Withdrawn | Gaze-Contingent Music Reward Treatment for PTSD NCT05057624 | Research Foundation for Mental Hygiene, Inc. | N/A |
| Completed | The Pitt Center for Emergency Responder Wellness NCT05357586 | University of Pittsburgh | N/A |
| Active Not Recruiting | Telehealth 2.0: Evaluating Effectiveness and Engagement Strategies for CPT-Text for PTSD NCT05037175 | Stanford University | N/A |
| Terminated | Couple's Retreats for Posttraumatic Stress Disorder NCT05274061 | The University of Texas Health Science Center at San Antonio | N/A |
| Active Not Recruiting | Transdiagnostic Versus Diagnosis-specific Cognitive-behavioral Therapy NCT05249543 | Karolinska Institutet | N/A |
| Completed | Using mHealth to Improve Emotional Recovery After Pediatric Injury NCT04579198 | Medical University of South Carolina | N/A |
| Completed | Written Exposure Therapy for Nurses NCT06432374 | University of Texas at Austin | EARLY_Phase 1 |
| Recruiting | Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms NCT05414708 | Walter Reed National Military Medical Center | N/A |
| Unknown | Testing the Efficacy of a Mindfulness- and Acceptance-Based Smartphone App for PTSD: A Randomized Controlled T NCT04861311 | University of Nevada, Las Vegas | Phase 1 |
| Unknown | Testing a Mindfulness/Acceptance-Based Smartphone App for Nurses Impacted by the COVID-19 Pandemic NCT05157035 | University of Nevada, Las Vegas | EARLY_Phase 1 |
| Active Not Recruiting | Physical Exercise as Adjunctive Therapy for Affective Disorder and Anxiety NCT05157386 | Region Stockholm | — |
| Completed | RCT for Innovating Stress-related eHealth NCT05305235 | University of North Carolina, Chapel Hill | N/A |
| Completed | Art Therapy QEEG Study for Service Members with a Traumatic Brain Injury and Posttraumatic Stress Symptoms NCT04776304 | Walter Reed National Military Medical Center | N/A |
| Completed | Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol NCT04912089 | University of California, San Diego | N/A |
| Withdrawn | TDCS-Augmented Prolonged Exposure Therapy NCT04327362 | Medical University of South Carolina | N/A |
| Withdrawn | TTI-0102 for Veterans With TBI NCT04262895 | VA Office of Research and Development | Phase 1 / Phase 2 |
| Completed | Development and Evaluation of a Tonic Immobility Focused Psychoeducational Intervention NCT05113277 | Florida State University | N/A |
| Unknown | Effectiveness of Basic Body Awareness Therapy in Post-traumatic Stress Disorders: A Randomized Clinical Trial NCT04396314 | Universitat de Lleida | N/A |
| Completed | Impact of Post-Traumatic Stress Disorder Treatment by Reconsolidation Therapy on Fibromyalgia Syndrome NCT04950426 | Centre Hospitalier Henri Laborit | Phase 2 |
| Completed | The Effect of a Combined Nature-based and Virtual Mindfulness Intervention on Perceived Stress in Healthcare W NCT04846790 | National Institutes of Health Clinical Center (CC) | N/A |
| Terminated | Testing the Efficacy of an Eye-tracking-based Treatment in Reducing Stress-related Symptoms in Veterans With P NCT05243459 | Tel Aviv University | Phase 2 / Phase 3 |
| Completed | Implementing a Skills Training Evidence-Based Treatment for Posttraumatic Stress Disorder in Primary Care NCT04937504 | Boston Medical Center | N/A |
| Completed | A Mobile Health Solution for Homework During CBT NCT04931199 | University of South Florida | N/A |
| Active Not Recruiting | Understanding and Testing Recovery Processes for PTSD and Alcohol Use Following Sexual Assault NCT04124380 | University of Washington | N/A |
| Completed | Multisite Feasibility of Compassion Meditation for Veterans With Posttraumatic Stress Disorder (PTSD) NCT04793698 | Veterans Medical Research Foundation | N/A |
| Completed | Cognitive Behavioural Therapy for Complicated Grief Reactions in Old Age NCT04694807 | University of Aarhus | N/A |
| Unknown | Intervention Through EMDR and CBT With Women Victim of Childhood Sexual Abuse. A Randomized Controlled Trial. NCT04813224 | Universidad Internacional de Valencia | N/A |
| Completed | Effects of Delta9-tetrahydrocannabinol (THC) on Retention of Memory for Fear Extinction Learning in PTSD: R33 NCT04080427 | Wayne State University | Phase 1 |
| Completed | Mobile Intervention for Veterans With PTSD and Anger NCT03733028 | VA Office of Research and Development | N/A |
| Completed | A Case Formulation Approach to Cognitive Processing Therapy NCT04407767 | VA Office of Research and Development | N/A |
| Completed | An Evaluation of Insomnia Treatment to Reduce Cardiovascular Risk in Patients With Posttraumatic Stress Disord NCT04498754 | Duke University | N/A |
| Completed | Preventing Trauma Symptoms in the Aftermath of Sexual Abuse in Children and Adolescents in Burundi NCT05136105 | University of Konstanz | N/A |
| Completed | The PaTHS Descriptive Correlational Longitudinal Study NCT04785482 | Children's Mercy Hospital Kansas City | — |
| Completed | Neurobiological Similarities of Tinnitus and PTSD NCT05981391 | The University of Texas Health Science Center at San Antonio | — |
| Completed | Comparing Group Therapies for Veterans With Depression and PTSD NCT03979040 | VA Office of Research and Development | N/A |
| Completed | PTSD Mobile App for Cancer Survivors NCT04058795 | Duke University | N/A |
| Completed | Mobile Mindfulness for Alcohol Use and PTSD Among Veterans NCT04769986 | University of Southern California | N/A |
| Completed | Couple HOPES (Helping Overcome PTSD and Enhance Satisfaction) NCT04763681 | York University | N/A |
| Recruiting | EMDR Treatment in PTSD Following Cardiac Events NCT04672551 | University of Zurich | N/A |
| Completed | Reducing Cannabis Overuse With Prazosin NCT04721353 | VA Puget Sound Health Care System | Phase 4 |
| Completed | Teaching Loved Ones to Help Veterans Optimize Their PTSD Care and Healing NCT04241094 | VA Office of Research and Development | N/A |
| Completed | Comparing Individual Therapies for Veterans With Depression, PTSD, and Panic Disorder NCT04293341 | VA Office of Research and Development | N/A |
| Completed | Treating Nightmares in Posttraumatic Stress Disorder With Dronabinol NCT04448808 | Charite University, Berlin, Germany | Phase 2 |
| Unknown | An Augmented Training Program for Preventing Post-Traumatic Stress Injuries Among Diverse Public Safety Person NCT05530642 | University of Regina | N/A |
| Completed | A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP2) NCT04077437 | Lykos Therapeutics | Phase 3 |
| Unknown | The Effects of Perioperative Painting Art Therapy (LOM® Solution Centered Art Therapy) in Surgical Patients NCT04524260 | University of Zurich | N/A |
| Completed | SMART-DAPPER: Leveraging the Depression And Primary-care Partnership for Effectiveness-implementation Research NCT03466346 | University of California, San Francisco | N/A |
| Unknown | Recovery Learning for Adolescents After Traumatic Experiences NCT04467320 | University of Bath | N/A |
| Completed | Tackling Intrusive Traumatic Memories After a Difficult Birth NCT04286724 | Antje Horsch | N/A |
| Completed | MGH Trauma-related Nightmares SDI Study NCT05195684 | Massachusetts General Hospital | N/A |
| Completed | Testing of a Mobile Web App to Decrease Posttraumatic Stress Symptoms in Women After Sexual Assault NCT04334356 | University of North Carolina, Chapel Hill | N/A |
| Completed | Tele-based Psychological Emotional Support for Informal CARegivers of COVID-19 Patients in Intensive Care NCT04409821 | Rigshospitalet, Denmark | N/A |
| Completed | Mobile Phone Based Intervention to Protect Mental Health in Healthcare Workers at Frontline Against COVID19 NCT04393818 | Fundació d'investigació Sanitària de les Illes Balears | Phase 3 |
| Terminated | Efficacy of TBCT, MBHP and PPT for PTSD During the Covid-19 Pandemics NCT04852770 | Fundação Bahiana de Infectologia | N/A |
| Completed | Couple HOPES (Helping Overcome PTSD and Enhance Satisfaction) NCT04231578 | Toronto Metropolitan University | N/A |
| Completed | Pilot Study Testing a Web-Based Moral Elevation Intervention for Veterans With PTSD and Moral Injury NCT03906240 | VA Office of Research and Development | N/A |
| Withdrawn | Administration of Prazosin to Prevent PTSD in Adult Women After Sexual Assault NCT03997864 | University of Colorado, Denver | Phase 4 |
| Completed | Integrated Intervention Post-Sexual Assault NCT04724746 | Medical University of South Carolina | N/A |
| Completed | Decreasing Suicide Risk Among Service Members With Posttraumatic Stress NCT04225130 | Boston VA Research Institute, Inc. | N/A |
| Completed | Predicting Treatment Outcomes With Intensive Outpatient Treatment for PTSD NCT04307498 | The University of Texas Health Science Center at San Antonio | N/A |
| Completed | Examining Changes in Microbiota Over the Course of PTSD Treatment NCT04109196 | Rush University Medical Center | N/A |
| Completed | Telephone Delivery of Cognitively Augmented Behavioral Activation (CABA) NCT04200976 | Portland VA Medical Center | N/A |
| Terminated | Predicting SSRI Efficacy in Veterans With PTSD NCT04183205 | VA Office of Research and Development | Phase 4 |
| Completed | Leveraging Implementation Science to Increase Access to Trauma Treatment for Incarcerated Drug Users NCT04007666 | University of Arkansas | N/A |
| Completed | Exercising With Anxiety: Can Cognitive Behavioural Techniques Help People With Anxiety-related Disorders Exerc NCT04026152 | University of Regina | N/A |
| Completed | Intervention for IPV-exposed Pregnant Women NCT04068662 | University of Notre Dame | N/A |
| Terminated | Neurosteroids in PTSD - Biomarkers to Therapeutics NCT03491007 | VA Office of Research and Development | Phase 2 |
| Completed | Narrative Exposure Therapy (NET) NCT03777553 | VA Office of Research and Development | N/A |
| Completed | RECONsolidation of Traumatic Memories to ResOLve Post Traumatic Stress Disorder (RECONTROLPTSD) NCT03827057 | Uniformed Services University of the Health Sciences | Phase 2 / Phase 3 |
| Completed | The Role of Expectations in the Development of Intrusive Memories NCT03950869 | Philipps University Marburg | N/A |
| Completed | Remote Study of NightWare for PTSD With Nightmares NCT03934658 | NightWare | N/A |
| Completed | Neurosteroids for PTSD in Veterans NCT03799562 | VA Office of Research and Development | Phase 2 |
| Recruiting | Risk and Resiliency Factors in the RCMP: A Prospective Investigation NCT05527509 | University of Regina | N/A |
| Unknown | Floatation-REST (Reduced Environmental Stimulation Therapy) for Anxiety and Depression NCT03899090 | Laureate Institute for Brain Research, Inc. | N/A |
| Completed | Umuryango Ukomera Uri Hamwe - Families Are Strong Together NCT04061954 | University of Konstanz | N/A |
| Completed | Inflammation and Threat Sensitivity in PTSD NCT03048929 | University of California, San Francisco | EARLY_Phase 1 |
| Completed | Improving Function Through Primary Care Treatment of Posttraumatic Stress Disorder (PTSD) NCT03581981 | VA Office of Research and Development | N/A |
| Completed | Assessment and Treatment of Cognitive Functioning Deficits in Veterans With PTSD NCT03696225 | VA Office of Research and Development | N/A |
| Completed | Biopsychosocial Effect of Service Dog Training on Post-traumatic Stress (PTS) and Post Concussive Symptoms NCT03907254 | Henry M. Jackson Foundation for the Advancement of Military Medicine | N/A |
| Unknown | Assessment of Dissociative Traumatic Disorders NCT04379648 | Januel | N/A |
| Unknown | NightWare Open Enrollment Study NCT03828656 | NightWare | N/A |
| Terminated | Exercise Maintenance in Chronic Pain and PTSD NCT03644927 | Boston University | N/A |
| Completed | 3MDR to Treat PTSD With mTBI (3MDR) NCT03796936 | Walter Reed National Military Medical Center | Phase 2 |
| Completed | Targeted Strategies to Accelerate Evidence-Based Psychotherapy (EBP) Implementation in Military Settings NCT03663452 | Palo Alto Veterans Institute for Research | N/A |
| Completed | Posttraumatic Stress Disorder in Parents and Children After Discharge From the Pediatric Intensive Care Unit NCT05186844 | Eskisehir Osmangazi University | — |
| Withdrawn | Risk Prediction for Alzheimer Dementia With Brain Imaging and Genetics NCT03641768 | Duke University | N/A |
| Completed | Implementation of Group Problem Management Plus (PM+) in Adult Syrian Refugees in Turkey: RCT (STRENGTHS) NCT03960892 | Istanbul Sehir University | N/A |
| Unknown | Health and Quality of Life Among Resettled Syrians in Norway NCT03742128 | Norwegian Center for Violence and Traumatic Stress Studies | — |
| Completed | Effectiveness of Group Focused Psychosocial Support for Adults Affected by Humanitarian Crises NCT03747055 | George Washington University | N/A |
| Completed | A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP1) NCT03537014 | Lykos Therapeutics | Phase 3 |
| Completed | A Self-Management Program for Completers of Trauma-Focused Therapy for PTSD NCT03225859 | VA Office of Research and Development | N/A |
| Completed | Neuromodulatory Treatments for Pain Management in TBI NCT03418129 | Duke University | N/A |
| Completed | Swiss TrAumatic biRth Trial NCT03576586 | Centre Hospitalier Universitaire Vaudois | N/A |
| Completed | The Use of a Novel Peer Education Program for Improving PTSD Treatment Engagement Among Veterans NCT03521999 | VA Office of Research and Development | N/A |
| Completed | Enhancement of PTSD Treatment With Computerized Executive Function Training NCT03260127 | VA Office of Research and Development | N/A |
| Completed | Implementation of Problem Management Plus (PM+) in Adult Syrian Refugees in Turkey: Pilot NCT03567083 | Istanbul Sehir University | N/A |
| Completed | Cognitive Training for PTSD NCT03316196 | VA Office of Research and Development | N/A |
| Active Not Recruiting | Predicting Responses to PTSD Treatment With Iris and Cardiovascular Tests NCT03539614 | VA Office of Research and Development | Phase 3 |
| Completed | Acupuncture for PTSD NCT02869646 | VA Office of Research and Development | N/A |
| Completed | Prevention of Mental Health Problems in People Exposed to a Recent Highly Stressful Event. NCT04314115 | Universidad Santo Tomas, Chile | N/A |
| Completed | Study of Safety and Effects of MDMA-assisted Psychotherapy for Treatment of PTSD (Canada) NCT03485287 | Lykos Therapeutics | Phase 2 |
| Completed | Reintegrating Children Living at Landfills in Burundi Into Society by Means of a Comprehensive Family Program NCT03846154 | University of Konstanz | N/A |
| Completed | Outcomes After Spinal Cord Injury (OASIS) NCT03624218 | Baylor Research Institute | N/A |
| Completed | Yoga/Pranayama for Posttraumatic Stress Disorder NCT03748121 | Universität Duisburg-Essen | N/A |
| Completed | An Open-Trial of Web-Prolonged Exposure (Web-PE) Among Active-Duty Military NCT03337750 | University of Pennsylvania | N/A |
| Completed | Improving Veteran Adherence to Treatment for PTSD Through Partnering With Families NCT03256227 | VA Office of Research and Development | N/A |
| Unknown | Shortened Prolonged Exposure Therapy for Chronic PTSD in Taiwanese Adults NCT03391297 | Chang Gung University | N/A |
| Completed | Efficacy Trial of Stress Check-Up NCT03423394 | University of Washington | N/A |
| Completed | Bounce Back Now: A Low-Cost Intervention to Facilitate Post-Disaster Recovery NCT03403738 | Medical University of South Carolina | N/A |
| Terminated | RCT: Fentanyl Plus Ketamine Versus Fentanyl Alone for Acute Burn Pain NCT03305055 | Johns Hopkins University | Phase 4 |
| Completed | Treating Violence-related PTSD and Substance Risk in Low-income, Urban Adolescents NCT03737383 | State University of New York at Buffalo | N/A |
| Completed | Improving Psychosocial Functioning in Older Veterans With PTSD NCT02803125 | VA Office of Research and Development | N/A |
| Unknown | Neuroeconomics of Social Behavior Following Trauma Exposure NCT03383536 | Mclean Hospital | — |
| Completed | Effectiveness and Acceptability of Stellate Ganglion Block for Posttraumatic Stress Disorder Symptoms - Accept NCT03302312 | RTI International | — |
| Unknown | Addressing Traumatic Stress Symptoms in Children NCT03334942 | Children's Hospital of Philadelphia | N/A |
| Unknown | Stress, Sleep and Cardiovascular Risk NCT03487991 | Howard University | N/A |
| Completed | The Mobile PTSD Coach App in Acute Injury Survivors NCT03247179 | University of Pittsburgh | N/A |
| Completed | A Comparison of CPT Versus ART Versus WL NCT03384706 | University of Cincinnati | N/A |
| Completed | Sensation Awareness Focused Training for Spouses NCT03129204 | University of South Florida | N/A |
| Completed | Improving Sleep to Reduce Risk for Substance Use Disorder NCT03226132 | Florida State University | N/A |
| Completed | The Modular Protocol for Mental Health (MPMH) NCT03143634 | Medical Research Council Cognition and Brain Sciences Unit | Phase 1 / Phase 2 |
| Completed | Study of the Effects of Oxytocin on Attentional Bias and Startle in PTSD NCT03211013 | Palo Alto Veterans Institute for Research | EARLY_Phase 1 |
| Completed | Effects of Delta-9 Tetrahydrocannabinol (THC) on Retention of Memory for Fear Extinction Learning in PTSD: R61 NCT03008005 | Wayne State University | Phase 4 |
| Completed | Cancer Distress Coach Mobile App Trial NCT02986152 | Duke University | N/A |
| Completed | Closed Loop Vagal Nerve Stimulation for Patients With Posttraumatic Stress Disorder NCT02992899 | Emory University | Phase 3 |
| Completed | Riluzole Effects on Hippocampus Biomarkers NCT04630444 | Mclean Hospital | EARLY_Phase 1 |
| Completed | A Pilot Evaluation of the Pregnant Moms' Empowerment Program NCT05011825 | University of Notre Dame | N/A |
| Completed | Adressing PTSD Symptoms and Aggressive Behavior in Vulnerable Children in Burundi NCT03498482 | University of Konstanz | N/A |
| Completed | An RCT of a Primary Care-Based PTSD Intervention: Clinician-Supported PTSD Coach NCT02685358 | VA Office of Research and Development | N/A |
| Completed | Evaluating Safety and Efficacy of Cannabis in Participants With Chronic Posttraumatic Stress Disorder NCT02517424 | Tilray | Phase 2 |
| Completed | Reminder Focused Positive Psychiatry in Adolescents With ADHD and PTSD NCT04336072 | University of California, Los Angeles | N/A |
| Completed | Suvorexant and Sleep's Benefits to Therapeutic Exposure for Posttraumatic Stress Disorder NCT02849548 | Howard University | Phase 4 |
| Completed | Pilot Study of the Safety and Efficacy of Four Different Potencies of Smoked Marijuana in 76 Veterans With PTS NCT02759185 | Multidisciplinary Association for Psychedelic Studies | Phase 2 |
| Completed | Study of Effectiveness and Implementation of a Mental Health Intervention With Conflict-affected Communities i NCT03058302 | Johns Hopkins Bloomberg School of Public Health | N/A |
| Completed | Cognitive Behavioral Therapy to Increase CPAP Adherence in Veterans With PTSD NCT02641496 | VA Office of Research and Development | N/A |
| Completed | FOCUS:Families OverComing Under Stress NCT02992405 | Cedars-Sinai Medical Center | N/A |
| Completed | Examining the Effects of Reduced Environmental Stimulation on Anxiety NCT03051074 | Laureate Institute for Brain Research, Inc. | N/A |
| Completed | A Smartphone Intervention With Telemedicine Support for Management of Post-traumatic Stress Disorder: A Random NCT02956902 | Ontario Shores Centre for Mental Health Sciences | N/A |
| Completed | Mobile Health Application for Family and Behavioral Health Provider Communication NCT02954146 | InferLink Corporation | N/A |
| Completed | Sleep and Wellbeing Study NCT03012685 | University of Oxford | — |
| Completed | Study to Promote Innovation in Rural Integrated Telepsychiatry NCT02738944 | University of Washington | N/A |
| Completed | Online Coping Skills Counseling for Problem Gambling and Trauma NCT03145792 | University of Windsor | N/A |
| Completed | The Attachment, Regulation and Competency (ARC) Framework NCT05155228 | Justice Resource Institute | N/A |
| Completed | NET for SGBV Survivors in Eastern DR Congo NCT02989987 | University of Konstanz | N/A |
| Completed | Comparative Effectiveness of Two Treatments for Veterans With PTSD NCT02586064 | VA Office of Research and Development | N/A |
| Completed | Imaging Biomarkers of Mild Traumatic Brain Injury: a Longitudinal Cohort Study NCT02868684 | First Affiliated Hospital Xi'an Jiaotong University | — |
| Completed | An Early Intervention to Increase Maternal Self-efficacy After Preterm Birth NCT02736136 | Centre Hospitalier Universitaire Vaudois | N/A |
| Completed | A Controlled Trial of Losartan in Posttraumatic Stress Disorder NCT02709018 | University of California, San Diego | N/A |
| Completed | MDMA-Assisted Cognitive-Behavioral Conjoint Therapy (CBCT) in Dyads in Which 1 Member Has Chronic PTSD NCT02876172 | Lykos Therapeutics | Phase 1 / Phase 2 |
| Completed | Evaluation of Outcomes Following Surf Therapy NCT02857751 | United States Naval Medical Center, San Diego | — |
| Completed | CAP: Doxazosin in the Treatment of Co-Occurring PTSD and Alcohol Use Disorders NCT02500602 | VA Office of Research and Development | Phase 2 |
| Completed | Effectiveness and Acceptability of Stellate Ganglion Block for Posttraumatic Stress Disorder Symptoms - Effect NCT03077919 | RTI International | N/A |
| Completed | Suvorexant and Trauma Related Insomnia NCT02704754 | Howard University | Phase 4 |
| Completed | Emotional Working Memory Training for Veterans With PTSD Symptoms NCT02766296 | Milwaukee VA Medical Center | N/A |
| Completed | Strategic Memory and Reasoning Training for Cognitive Problems NCT04554537 | Dr. Kristin Samuelson | N/A |
| Completed | CAP-Ketamine for Antidepressant Resistant PTSD NCT02655692 | VA Office of Research and Development | Phase 2 |
| Completed | Establishing Efficacy of a Functional-Restoration Based CAM Pain Management Program in Post-9/11 Veterans NCT02657317 | The University of Texas Health Science Center at San Antonio | N/A |
| Completed | Trauma-Focused Equine-Assisted Therapy (TF-EAT) for Veterans With PTSD NCT03068325 | Research Foundation for Mental Hygiene, Inc. | N/A |
| Completed | CPT Group for DBT Clients With Co-Occurring Borderline Personality Disorder and PTSD NCT02574429 | St. Joseph's Healthcare Hamilton | N/A |
| Unknown | TOP Implementation Project NCT02737098 | VA Office of Research and Development | N/A |
| Completed | Integrated Treatment for Posttraumatic Stress Disorder and Substance Abuse in Young Adults NCT02667119 | UConn Health | N/A |
| Enrolling By Invitation | Neurobiology of Posttraumatic Stress Disorder Dysfunction and Recovery Following Cognitive Processing Therapy NCT02695953 | Milissa Kaufman | — |
| Unknown | Low Back Pain and Comorbid Posttraumatic Stress Disorder NCT03244046 | University of Southern Denmark | N/A |
| Withdrawn | Results From a 24 Week Trial of EMDR Combined With Venlafaxine XR NCT02433353 | Bayne-Jones Army Community Hospital | Phase 4 |
| Completed | Prognostication of Need for Rehabilitation and Special Support in ICU Survivors NCT02679157 | Karolinska University Hospital | — |
| Completed | Mind-Body Skills Groups for Behavioral and Emotional Problems in War-Traumatized Male Adolescents in Gaza NCT02671487 | The Center for Mind-Body Medicine | N/A |
| Completed | FKBP5 Methylation and Childhood Emotional Abuse in Complex Posttraumatic Stress Disorder: Investigating the Re NCT06433843 | University Hospital Tuebingen | N/A |
| Terminated | Intensive 7-day Treatment for PTSD Combining Ketamine With Exposure Therapy NCT02727998 | Yale University | Phase 2 |
| Completed | Using Attentional Bias Modification to Address Trauma Symptoms NCT02615717 | University of Nebraska Lincoln | N/A |
| Completed | The Trauma of Betrayal: Treating Adjustment Disorder With Reconsolidation Blockade Under Propranolol NCT03151681 | Douglas Mental Health University Institute | Phase 2 / Phase 3 |
| Completed | Integrated Treatment for Co-occurring Eating Disorders and Posttraumatic Stress Disorder NCT03502564 | University Health Network, Toronto | N/A |
| Completed | Behavioral Activation + Cognitive Processing Therapy for PTSD and Comorbid MDD NCT02874131 | United States Naval Medical Center, San Diego | N/A |
| Completed | Building Resilience After Childhood Emergencies (BRACE) NCT02898883 | Case Western Reserve University | N/A |
| Completed | A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity NCT02655354 | University of Washington | N/A |
| Completed | Randomized Controlled Trial of Interpersonal Psychotherapy for Depression and PTSD Among HIV+ Women in Kenya NCT02320799 | University of California, San Francisco | N/A |
| Completed | Improving Functional Outcomes of Veterans With PTSD and Tobacco Dependence NCT02576899 | VA Office of Research and Development | Phase 1 |
| Completed | Supported Employment in Patient Aligned Care Teams NCT02400736 | VA Office of Research and Development | N/A |
| Completed | Stepped Care for Children After Trauma: Optimizing Treatment NCT02537678 | University of South Florida | N/A |
| Completed | Variable-length Cognitive Processing Therapy for Combat-Related PTSD NCT02313818 | Duke University | N/A |
| Completed | Cognitively Augmented Behavioral Activation for Veterans With Comorbid TBI/PTSD NCT02391402 | VA Office of Research and Development | N/A |
| Completed | Decreasing Youth Involvement in Violence in Burundi NCT02503488 | University of Konstanz | N/A |
| Completed | LED Treatment to Improve Cognition and Promote Recovery in TBI NCT02404402 | VA Office of Research and Development | N/A |
| Completed | Brief Restructuring Intervention Following Trauma Exposure NCT02808468 | University of Washington | N/A |
| Completed | Group CBT for Aggression in Veterans NCT02233517 | VA Office of Research and Development | N/A |
| Completed | A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity Pilot NCT02335125 | University of Washington | N/A |
| Completed | Adjunctive Brief Behavioral Treatment of Insomnia (BBTI) for Sleep Intervention (SI) NCT02248675 | VA Office of Research and Development | N/A |
| Completed | Compassion Meditation for PTSD NCT02372396 | Veterans Medical Research Foundation | N/A |
| Completed | Case Series for Traumatized Refugees With Khat Dependence NCT02259530 | University of Konstanz | N/A |
| Completed | Equine Assisted Psychotherapy for PTSD NCT03039361 | University of New Mexico | N/A |
| Completed | Loving-Kindness Meditation for PTSD NCT01962714 | VA Office of Research and Development | N/A |
| Terminated | Tobacco Treatment as Augmentation for Cognitive Processing Therapy for PTSD NCT02012452 | VA Office of Research and Development | N/A |
| Completed | Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety Disorders NCT01947647 | VA Office of Research and Development | N/A |
| Terminated | Randomized, Double-blind, Controlled of MDMA-assisted Psychotherapy in 12 Subjects With PTSD NCT01958593 | Lykos Therapeutics | Phase 2 |
| Completed | rTMS for PTSD Comorbid With Major Depressive Disorder NCT02273063 | Butler Hospital | N/A |
| Unknown | Controlled Trial of Early Intervention With Children and Adolescents Exposed to Nonrelational Traumatic Events NCT02299583 | Carolina Magdalene Maier | N/A |
| Completed | PRIME: Cognitive Outcome Following Major Burns NCT03242395 | Chelsea and Westminster NHS Foundation Trust | — |
| Completed | Client-directed Cognitive Processing Therapy NCT02684994 | University of Indianapolis | N/A |
| Completed | Clinical Effectiveness Trial of In-Home Cognitive Processing Therapy for Combat-Related PTSD NCT02290847 | The University of Texas Health Science Center at San Antonio | N/A |
| Completed | Treatment of Posttraumatic Stress Disorder and Aggressive Behavior in Soldiers and Ex-combatants NCT02242136 | University of Konstanz | N/A |