NCT02404402

LED Treatment to Improve Cognition and Promote Recovery in TBI

Noninvasive LED Treatment to Improve Cognition and Promote Recovery in Blast TBI

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 8 (actual)
• Sponsor: VA Office of Research and Development · Federal
• Sex: All
• Age: 21 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

This study investigates the efficacy of a novel neuromodulation treatment, light emitting diodes (LED), on cognition, neuropsychiatric status and quality of life in individuals with traumatic brain injury (TBI).

Detailed description

The most common traumatic brain injury (TBI)-associated problems are cognitive deficits and neuropsychiatric problems, such as sleep disturbance and PTSD. This study evaluates a novel neuromodulation intervention, light emitting diodes (LED), for treatment of patients with TBI. LED is a noninvasive, non-thermal, painless treatment, which does not involve any needles or any form of surgery. LED treatment improves cellular activity of the brain tissue that has been damaged by TBI. Half of the study participants will receive active LED treatment, and a control group will receive sham LED. This study takes place in Boston, Massachusetts: at the VA Boston Healthcare System.

Conditions

• Traumatic Brain Injury
• Posttraumatic Stress Disorder

Interventions

Type	Name	Description
OTHER	LED	Low Level Light Therapy
OTHER	sham LED	Inactive (sham) LED treatment

Timeline

• Start date: 2015-05-01
• Primary completion: 2025-06-30
• Completion: 2025-06-30
• First posted: 2015-03-31
• Last updated: 2026-04-15

Locations

1 site across 1 country: United States