| Not Yet Recruiting | A Phase 2a Efficacy, Safety, Tolerability, and PK Study of SYT-510 in Participants With Generalized Anxiety Di NCT07478744 | Synendos Therapeutics AG | Phase 2 |
| Not Yet Recruiting | RE104 Safety and Efficacy Study in Generalized Anxiety Disorder NCT07489651 | Reunion Neuroscience Inc | Phase 2 |
| Not Yet Recruiting | Mapsd Dual-target cTBS (Auditory Cortex and M1) for Generalized Anxiety Disorder NCT07403591 | Anhui Medical University | N/A |
| Not Yet Recruiting | Pharmacokinetic Study of Buagafuran Capsules in Participants With Hepatic Impairment and Normal Hepatic Functi NCT07457190 | Beijing Union Pharmaceutical Factory Ltd | Phase 1 |
| Not Yet Recruiting | Metacognitive Therapy Compared to Cognitive-behavioral Therapy NCT07382323 | Karolinska Institutet | N/A |
| Not Yet Recruiting | Ultra-brief Psychological Treatments for Emotional Symptoms and Disorders NCT06909669 | Universidad de Córdoba | N/A |
| Not Yet Recruiting | Testing a Precision Psychotherapy System for Low-income Patients NCT05118594 | National Council of Scientific and Technical Research, Argentina | N/A |
| Not Yet Recruiting | Electroacupuncture for Generalized Anxiety Disorder: Clinical Efficacy and Neuroimaging Mechanisms NCT07392645 | Lishu Gao | N/A |
| Recruiting | Internet-Delivered Cognitive Behavioral Intervention for Youths With Anxiety Disorders NCT06661460 | Lund University | N/A |
| Recruiting | Implementing Team-Based Treatment for Pediatric Anxiety in Community Mental Health Settings NCT06934525 | Bradley Hospital | N/A |
| Recruiting | Cohort Study on Medical Students' Mental Health NCT07305701 | Centre Hospitalier Régional d'Orléans | — |
| Recruiting | Prospective Clinical Trial of Crisugabalin Capsules in the Treatment of Generalized Anxiety Disorder NCT07330648 | Anhui Medical University | Phase 2 |
| Recruiting | Navigated cTBS for the Treatment of Generalized Anxiety Disorder NCT07121712 | WANG KAI | N/A |
| Recruiting | Stepped Versus Stratified Care for Anxiety Disorders in Youth NCT06942429 | Region Skane | N/A |
| Recruiting | Mindful Self-compassion for Anxiety and Depression: Impact of Delivery Method NCT07028216 | Georgetown University | N/A |
| Recruiting | Transdiagnostic Internet-delivered Intervention for Adolescents With Anxiety and Depression NCT06724666 | Babes-Bolyai University | N/A |
| Recruiting | Teletherapy vs. In-Person Cognitive Behavioral Therapy for Generalized Anxiety Disorder NCT07119515 | Government College University Faisalabad | N/A |
| Not Yet Recruiting | Understanding of Participation Trends Within Generalized Anxiety Disorder Patients Involved in Clinical Trials NCT06254157 | Power Life Sciences Inc. | — |
| Enrolling By Invitation | Metacognitive Therapy for Depression and Generalized Anxiety Disorder in Primary Care, Blended Version of Medi NCT06928428 | Region Stockholm | N/A |
| Recruiting | RCT of Short-Term Psychoanalytic vs. Cognitive Behavioral Therapy for GAD NCT06831708 | Beykoz University | N/A |
| Recruiting | Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness NCT06376734 | Brigham and Women's Hospital | Phase 2 |
| Recruiting | A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Panorama) NCT06809595 | Definium Therapeutics US, Inc. | Phase 3 |
| Recruiting | Neurofeedback Enhanced Cognitive Reappraisal Training - Phase 4 NCT06563310 | University of Michigan | N/A |
| Recruiting | Use of CBD in the Treatment of Anxiety NCT06672666 | University of Florida | Phase 2 |
| Completed | Treating Young Adult Generalized Anxiety Disorder With Text-Message Delivered Cognitive Behavioral Therapy NCT06774573 | The University of Tennessee, Knoxville | N/A |
| Recruiting | A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Voyage) NCT06741228 | Definium Therapeutics US, Inc. | Phase 3 |
| Not Yet Recruiting | Efficacy and Safety of Inhaled NC-107 As Compared to Placebo After 4 Weeks of Treatment in Patients with Anxie NCT06656806 | Trinity Hypertension & Metabolic Research Institute | EARLY_Phase 1 |
| Not Yet Recruiting | Effects of rTMS on the Anxiety State of Older Patients With GAD NCT05883774 | Yi Yang | N/A |
| Recruiting | Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder NCT06701903 | Intra-Cellular Therapies, Inc. | Phase 2 |
| Recruiting | Internet-delivered Cognitive-Behavioral Therapy for Adolescents With Autism and Anxiety NCT06537128 | Baylor College of Medicine | N/A |
| Recruiting | Adjunctive Treatment With L-methylfolate for Treatment-Resistant Generalized Anxiety Disorder: a Pilot Study NCT06218030 | Queen's University | Phase 4 |
| Recruiting | Study of ITI-1284 as an Adjunctive Treatment in Patients With Generalized Anxiety Disorder NCT06480383 | Intra-Cellular Therapies, Inc. | Phase 2 |
| Withdrawn | Cognitive Behavioral Therapy (CBT) for Late Life Anxiety NCT05380115 | Wake Forest University Health Sciences | N/A |
| Enrolling By Invitation | Operation of Brain Stimulation Equipment Under Remote Viewing Effectiveness Registry NCT06512324 | Biomedical Discoveries and Neuroscientific Foundations LLC | — |
| Active Not Recruiting | The Effect of Psychoeducation Based on Acceptance and Commitment Therapy Applied to Patients Diagnosed With Ge NCT06972563 | Arzu Çalışkan | N/A |
| Recruiting | The Effectiveness of Transdiagnostic CBT Protocol on Anxiety Disorders NCT06422728 | Ibn Haldun University | N/A |
| Active Not Recruiting | A Study of a N, N-dimethyltryptamine (DMT) Analog (CYB004) in Participants With Generalized Anxiety Disorder ( NCT06051721 | Cybin IRL Limited | Phase 2 |
| Recruiting | Massage for GAD: Neuroimaging and Clinical Correlates of Response NCT06506253 | University of Utah | N/A |
| Completed | Neurofeedback Enhanced Cognitive Reappraisal Training NCT06132659 | University of Michigan | N/A |
| Unknown | Behavioural Experiments for Generalized Anxiety in Adolescents - Pilot Study NCT06282133 | Universite du Quebec en Outaouais | N/A |
| Completed | CES for the Treatment of GAD in Young Adults NCT06124014 | Electromedical Products International, Inc. | N/A |
| Recruiting | Trigeminal Nerve Stimulation in Treatment-resistant Generalized Anxiety Disorder: a Feasibility Study NCT06278909 | Dr. Rafael Freire | N/A |
| Completed | Adaptation and Feasibility of the Community-Based Anxiety Program Tailored for Autism (CAPTA) NCT06046170 | Baylor College of Medicine | N/A |
| Completed | Transcranial Direct Current Stimulation (tDCS) in Different Psychiatric Disorders NCT07452835 | Menoufia University | N/A |
| Unknown | Transcutaneous Vagus Nerve Stimulation for Generalized Anxiety Disorder NCT06134323 | Xijing Hospital | N/A |
| Active Not Recruiting | Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive Disorder NCT05967468 | Baylor College of Medicine | N/A |
| Completed | Pivotal RCT to Test Safety and Efficacy of Digital Therapeutics 'ANZEILAX' for Managing Generalized Anxiety Di NCT06010654 | HAII corp.ltd | N/A |
| Recruiting | Phase 3 Clinical Trial of Buagafuran Capsules in the Treatment of GAD NCT06243640 | Beijing Union Pharmaceutical Factory Ltd | Phase 3 |
| Recruiting | Phase Ⅲ Clinical Trial of Buagafuran Capsules in the Treatment of GAD NCT06243614 | Beijing Union Pharmaceutical Factory Ltd | Phase 3 |
| Recruiting | A Study to Evaluate Efficacy and Safety of Toludesvenlafaxine Hydrochloride Sustained-release Tablets in Gener NCT05970510 | Luye Pharma Group Ltd. | Phase 3 |
| Completed | ENCALM: A Study of ENX-102 as a Monotherapy Treatment in Patients With Generalized Anxiety Disorder NCT05749055 | Engrail Therapeutics INC | Phase 2 |
| Unknown | Development of Online EMDR Therapy System and Its Comparative Testing With Face-to-Face EMDR Therapy for Treat NCT05785312 | Khushal Khan Khattak Univeristy, Karak, Pakistan | N/A |
| Active Not Recruiting | Effects and Mechanisms of Change of Internet Delivered Cognitive Behavior Therapy for Generalized Anxiety Diso NCT05849493 | Karolinska Institutet | N/A |
| Recruiting | Clinical Trial of Shugan Jieyu Capsule in Generalized Anxiety Disorder NCT05772104 | Sichuan Jishengtang Pharmaceutical Co., Ltd. | Phase 3 |
| Completed | Mental Health Assessment and Prescribing by Alberta Pharmacists NCT04410575 | University of Alberta | N/A |
| Completed | A Clinical Study That Will Measure How Well SEP-363856 Works and How Safe it is in Adults With Generalized Anx NCT05729373 | Otsuka Pharmaceutical Development & Commercialization, Inc. | Phase 2 / Phase 3 |
| Completed | Generalized Anxiety Therapy Effectiveness NCT05748652 | Big Health Inc. | N/A |
| Completed | Feasibility and ML Training Investigation of the Senseye DT for Diagnosis of Adults with PTSD NCT05717439 | Senseye, Inc. | — |
| Unknown | Virtual Reality for Generalized Anxiety Disorders NCT05895721 | Clinical Research Centre, Malaysia | N/A |
| Completed | Level of Physical Activity and Fear Learning NCT05203731 | NYU Langone Health | N/A |
| Recruiting | Where We All Meet: ACT Approach to Adolescents Anxiety Disorders NCT05906849 | University of Coimbra | N/A |
| Completed | Internet Delivered Cognitive Behavior Therapy Based on Intolerance of Uncertainty NCT05820568 | Karolinska Institutet | N/A |
| Recruiting | CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy NCT05467683 | University of Texas at Austin | N/A |
| Completed | Computerized Intervention Targeting the Error-Related Negativity and Balance N1 in Anxious Children NCT05503017 | Florida State University | N/A |
| Recruiting | Electroclinical Correlation of Anxiety NCT05393518 | University Hospital, Bordeaux | N/A |
| Active Not Recruiting | Clinical Trial of a Group Self-management Support Program for Anxiety Disorders NCT05124639 | Université de Sherbrooke | N/A |
| Unknown | Augmenting Mental Health Support Through a Supportive Text Messaging Program NCT05411302 | Vincent Agyapong | N/A |
| Recruiting | Respiratory Training in the Treatment of Transdiagnostic Pathological Anxiety NCT05427708 | University of Texas at Austin | N/A |
| Completed | Dietary Counselling Plus Omega-3 Supplementation in the Treatment of Generalized Anxiety Disorder NCT05573672 | The Canadian College of Naturopathic Medicine | Phase 2 |
| Completed | Clinical Markers of Panic and Generalized Anxiety Disorder NCT06071819 | University of Milano Bicocca | — |
| Recruiting | BreathinG-induced Myocardial and Cerebral Perfusion in Anxiety Disorders NCT05574140 | McGill University Health Centre/Research Institute of the McGill University Health Centre | — |
| Completed | Comparing the Efficacy of Two Neurofeedback Protocols for Generalized Anxiety Disorder NCT06361953 | Shahid Beheshti University of Medical Sciences | N/A |
| Terminated | rTMS Pilot for Anxiety NCT05306977 | University of Pennsylvania | N/A |
| Completed | Digital Interventions As an Add-on Tool in Generalized Anxiety Disorder Treatment NCT05375851 | Hospital de Clinicas de Porto Alegre | N/A |
| Completed | Internet-Based, Parent-Led Cognitive-Behavioral Therapy for Anxiety in Youth With ASD NCT05284435 | Baylor College of Medicine | N/A |
| Active Not Recruiting | Transdiagnostic Versus Diagnosis-specific Cognitive-behavioral Therapy NCT05249543 | Karolinska Institutet | N/A |
| Active Not Recruiting | Treatment of Anxiety Disorders With Trigeminal Nerve Stimulation NCT04931134 | Dr. Rafael Freire | N/A |
| Recruiting | Mindful Self-Compassion for Anxiety Disorders and Depression NCT05671419 | Georgetown University | N/A |
| Recruiting | Validating an Autonomous Interactive Internet-Based Delivery of an Empirically Supported Cognitive Behavioral NCT05117255 | University of Minnesota | N/A |
| Unknown | Triage Survey for Psychiatry Research Eligibility NCT05800925 | Adams Clinical | — |
| Active Not Recruiting | Physical Exercise as Adjunctive Therapy for Affective Disorder and Anxiety NCT05157386 | Region Stockholm | — |
| Unknown | Cannabidiol for the Treatment of Anxiety Disorders: An 8-Week Pilot Study NCT03549819 | McMaster University | Phase 3 |
| Recruiting | MBSR Mechanisms in GAD NCT05064813 | NYU Langone Health | N/A |
| Terminated | Empower Neuromodulation System - Pilot Study for Anxiety Treatment NCT04901481 | Theranova, L.L.C. | N/A |
| Unknown | Acceptability/Feasibility of IU Intervention NCT05172427 | Ohio University | N/A |
| Withdrawn | A Study To Assess Adverse Events and Change in Disease Activity With Oral Cariprazine When Added to Antidepres NCT04965272 | AbbVie | Phase 2 |
| Completed | Digital Therapeutic for Major Depressive Disorder (MDD) and Generalized Anxiety Disorder (GAD) NCT05016050 | Happify Inc. | N/A |
| Recruiting | Low-Intensity Focused Ultrasound Pulsation (LIFUP) for the Treatment of Generalized Anxiety Disorder (GAD) NCT04557891 | University of California, Los Angeles | N/A |
| Completed | Parent-based Treatment for Youth With Anxiety and Obsessive-compulsive Disorder NCT04922502 | Baylor College of Medicine | N/A |
| Recruiting | Evaluation of Primary Care Behavioral Health (PCBH) With the Addition of Self-help CBT - A Randomized Multicen NCT04900064 | Linnaeus University | N/A |
| Completed | Decision Aid for Patients With Generalized Anxiety Disorder: Protocol for a Randomized Controlled Trial NCT04364958 | Servicio Canario de Salud | N/A |
| Completed | Improving Attentional and Cognitive Control in the Psychological Treatment of Intrusive Thoughts NCT04225624 | Massachusetts General Hospital | N/A |
| Active Not Recruiting | Patient-centered Treatment of Anxiety After Low-Risk Chest Pain in the Emergency Room NCT04811521 | Indiana University | N/A |
| Completed | Comparing the Efficacy of E-CBT to Mental Health Coaching for GAD NCT04754438 | Dr. Nazanin Alavi | N/A |
| Withdrawn | Cannabinoids for the Treatment of Anxiety Disorders: An 8-Week Pilot Study NCT04569760 | McMaster University | Phase 3 |
| Active Not Recruiting | Internet-delivered Cognitive Behavioral Treatment of Depression and Anxiety in Latin American College Students NCT04780542 | Instituto Nacional de Psiquiatría Dr. Ramón de la Fuente | N/A |
| Terminated | Cognitive Behavioral Therapy Group for Older Adults Delivered by Telethealth NCT04714164 | Nova Scotia Health Authority | N/A |
| Suspended | Group CBT for Intolerance of Uncertainty NCT04512378 | University of Manitoba | N/A |
| Completed | Optimizing Cognitive Remediation NCT04395157 | VA Office of Research and Development | — |
| Active Not Recruiting | Brain Stimulation & Generalized Anxiety Study NCT04751864 | ProofPilot | Phase 4 |
| Completed | Evaluation of Effects of CBD Products on Anxiety Among U.S. Women NCT05108220 | Radicle Science | — |
| Unknown | An Augmented Training Program for Preventing Post-Traumatic Stress Injuries Among Diverse Public Safety Person NCT05530642 | University of Regina | N/A |
| Recruiting | A Transdiagnostic, Self-guided Internet Intervention ("Velibra") for Waitlist Patients With Anxiety Disorders NCT04793828 | Charite University, Berlin, Germany | N/A |
| Completed | Computerized Cognitive Training in Middle-Aged Adults With Generalized Anxiety Disorder: A Pilot Study NCT04421690 | University of Missouri-Columbia | N/A |
| Completed | Anxiety Symptoms in Relation to Use of Hemp-derived, Full Spectrum Cannabidiol (CBD) NCT05023759 | Formula30A LLC | — |
| Completed | Efficacy of Online CBT for GAD Compared to Pharmaceutical Interventions NCT04478526 | Dr. Nazanin Alavi | N/A |
| Completed | Transdiagnostic Internet-delivered REBT Intervention for Adolescents' Internalizing Problems NCT04179526 | Babes-Bolyai University | N/A |
| Unknown | Physical and Psychological Health Trajectories in the Context of Coronary Heart Disease NCT04433832 | Laval University | — |
| Completed | Parent-Led Cognitive-Behavioral Teletherapy for Anxiety in Youth With ASD NCT04111874 | Baylor College of Medicine | N/A |
| Recruiting | Risk and Resiliency Factors in the RCMP: A Prospective Investigation NCT05527509 | University of Regina | N/A |
| Completed | A 14 Week, Randomized, Placebo-Controlled Cross-Over Study of Methylphenidate Hydrochloride Controlled Release NCT03785223 | McMaster University | Phase 4 |
| Unknown | Floatation-REST (Reduced Environmental Stimulation Therapy) for Anxiety and Depression NCT03899090 | Laureate Institute for Brain Research, Inc. | N/A |
| Unknown | RECOVERY: A Transdiagnostic Intervention for Anxiety and Depression NCT03917550 | West University of Timisoara | N/A |
| Completed | Self-help Guided by Lay Providers for Anxiety in Older Adults NCT03768544 | Laval University | N/A |
| Completed | Music Therapy and Dialysis: A Pilot Investigation Into the Effectiveness of Patient-Selected Music Interventio NCT03925168 | Tulane University | N/A |
| Completed | Randomized Trial of Adult Participants With Generalized Anxiety Disorder NCT03829241 | Biohaven Pharmaceuticals, Inc. | Phase 3 |
| Completed | Self-selected or Predetermined Internet-based Treatment for Generalized Anxiety Disorder With Different Types NCT03807193 | Linkoeping University | N/A |
| Completed | Stepped-Care Cognitive-Behavioral Treatment for Youth With ASD and Anxiety NCT03720795 | Baylor College of Medicine | N/A |
| Terminated | Treatment of Adults With Generalized Anxiety Disorder Using Glutamine NCT04274114 | Hospital Universitario Dr. Jose E. Gonzalez | Phase 2 |
| Completed | Walking or High Intensity Exercise for Anxiety NCT03819426 | NYU Langone Health | N/A |
| Recruiting | Brief Smartphone Treatment Study NCT04846777 | Penn State University | N/A |
| Terminated | Transcranial Pulse Near-Infrared Light in Generalized Anxiety Disorder: a Placebo-Controlled Study NCT03420456 | Massachusetts General Hospital | N/A |
| Completed | Open Trial of an ACT Skills Group and Mobile App for Worry NCT03709433 | Utah State University | N/A |
| Completed | Pharmacogenomic-Guided Antidepressant Drug Prescribing in Cancer Patients NCT03674138 | H. Lee Moffitt Cancer Center and Research Institute | N/A |
| Completed | Brain Response Associated With Parent-based Treatment for Childhood Anxiety Disorders NCT03585010 | Yale University | N/A |
| Unknown | Improving Access to Child Anxiety Treatment NCT03528109 | Bradley Hospital | N/A |
| Completed | Treatments for Anxiety: Meditation and Escitalopram NCT03522844 | Georgetown University | Phase 4 |
| Completed | Cognitive-behavioral Therapy for Generalized Anxiety Disorder in Primary Care NCT03621371 | Karolinska Institutet | N/A |
| Completed | Predicting Treatment Response to Exposure Therapy Using Carbon Dioxide NCT03925987 | Laureate Institute for Brain Research, Inc. | N/A |
| Terminated | Echinacea Angustifolia (AnxioCalm) in Anxiety NCT03463018 | EuroPharma, Inc. | Phase 2 |
| Completed | The Role of Cognitive Control in the Transdiagnostic Conceptualization of "Intrusive Thoughts" NCT03414619 | Massachusetts General Hospital | N/A |
| Completed | SkillJoy Clinical Trial NCT05040061 | Skidmore College | N/A |
| Completed | Pharmacogenomic Testing to Optimize Antidepressant Drug Therapy NCT03591224 | John Papastergiou Pharmacy Ltd | N/A |
| Completed | Adapting an Effective CBT for Comorbidity to a Computer-Delivered Format NCT03300232 | University of Minnesota | N/A |
| Completed | Bioequivalence Study of Paroxetine Tablets and Paxil® Under Fasting and Fed Conditions in Chinese Healthy Volu NCT03504475 | Beijing Tongren Hospital | Phase 1 |
| Unknown | Rumination Focus Cognitive Behavior Therapy NCT03507114 | West University of Timisoara | N/A |
| Completed | 6-Session Treatment for Generalized Anxiety Disorder NCT03433625 | Universite du Quebec en Outaouais | N/A |
| Completed | Collabri Flex - Effect of Collaborative Care for People With Anxiety Disorders in General Practice NCT03113175 | Amager Hospital | N/A |
| Completed | Internet-delivered CBT for Adolescents With GAD NCT03469453 | Karolinska Institutet | N/A |
| Completed | Pragmatic Collaborative Care for Cardiac Inpatients With Depression or Anxiety NCT03118752 | Massachusetts General Hospital | N/A |
| Completed | Pilot Study of Virtual Reality for Providing Exposure Therapy to Children NCT03208348 | Minnesota HealthSolutions | N/A |
| Unknown | Pharmacogenetics in Primary Care Psychotropics NCT03232502 | University of Arizona | Phase 3 |
| Completed | The Modular Protocol for Mental Health (MPMH) NCT03143634 | Medical Research Council Cognition and Brain Sciences Unit | Phase 1 / Phase 2 |
| Unknown | Simplified Cognitive Behavioral Therapy for Generalized Anxiety Disorder and Depression NCT03329287 | Shanghai Mental Health Center | N/A |
| Completed | Transcutaneous Vagus Nerve Stimulation in Private Healthcare Center NCT03440255 | Kinesis Health Associates | N/A |
| Completed | Effect of Mindfulness Meditation on Physiological Response to Unpredictable Stimuli NCT03206437 | Georgetown University | N/A |
| Unknown | Effectiveness & Cost-effectiveness of Internet-delivered Interventions for Depression and Anxiety Disorders in NCT03188575 | Silver Cloud Health | N/A |
| Completed | Improving Access to the Treatment of Anxiety and Depression Among Young Adults NCT03156556 | Universite de Moncton | N/A |
| Completed | Implementation of Psychological Treatment in Generalized Anxiety NCT03079336 | University of Zurich | N/A |
| Completed | Examining the Effects of Reduced Environmental Stimulation on Anxiety NCT03051074 | Laureate Institute for Brain Research, Inc. | N/A |
| Completed | Dimensional Brain Behavior Predictors of CBT Outcomes in Pediatric Anxiety NCT02810171 | University of Michigan | N/A |
| Completed | Randomized Clinical Trial of a Mindfulness Based Intervention in Generalized Anxiety Disorder NCT03072264 | Hospital de Clinicas de Porto Alegre | N/A |
| Completed | Cognitive Behavioural Therapy for Anxiety Disorders in PD NCT02648737 | Maastricht University Medical Center | N/A |
| Completed | Clinical Trial of Transdiagnostic Cognitive-Behavior Therapy for Anxiety Disorders NCT02811458 | Université de Sherbrooke | N/A |
| Completed | Approach-Avoidance Conflict-a Multi-level Predictor for Therapy Response NCT02807480 | Laureate Institute for Brain Research, Inc. | N/A |
| Completed | Short-Term Efficacy and Mechanisms of Change of a Worry Postponement Intervention for Generalized Anxiety Diso NCT02806271 | Toronto Metropolitan University | N/A |
| Completed | Transdiagnostic REBT Prevention Program for Adolescents NCT02756507 | Babes-Bolyai University | N/A |
| Completed | Visual Mismatch Negativity in Attention Bias Modifcation Treatment for Anxiety NCT03016052 | Tel Aviv University | N/A |
| Unknown | Internet-delivered Transdiagnostic Intervention for Anxiety and Depression NCT02739607 | West University of Timisoara | N/A |
| Unknown | Efficacy and Safety Study of a IMSS Developed Phytopharmaceutical for the Treatment of Anxiety. NCT03702803 | Coordinación de Investigación en Salud, Mexico | Phase 2 |
| Active Not Recruiting | Physical Exercise Augmented CBT for GAD NCT02690441 | Solli Distriktspsykiatriske Senter | N/A |
| Completed | Efficacy of an Acceptance-based Group Behavioral Therapy for Generalized Anxiety Disorder. NCT03930095 | University of Sao Paulo General Hospital | N/A |
| Completed | Emotion Regulation Therapy for Clinical Worry and Rumination NCT04060940 | Douglas Mennin | N/A |
| Completed | Kava for the Treatment of Generalised Anxiety Disorder: A Double-Blind Randomised Placebo-Controlled Trial NCT02219880 | University of Melbourne | Phase 4 |
| Completed | Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia Nervosa NCT02615119 | Laureate Institute for Brain Research, Inc. | N/A |
| Completed | A Single-Component CBT for GAD NCT02552108 | Universite du Quebec en Outaouais | N/A |
| Withdrawn | Worry Exposure for Generalized Anxiety Disorder NCT02382224 | University of Texas at Austin | N/A |
| Unknown | Initial Severity and Antidepressant Efficacy for Anxiety Disorders: an Individual Patient Data Meta-analysis NCT02476136 | prof. Peter de Jonge | — |
| Completed | Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety Disorders NCT01947647 | VA Office of Research and Development | N/A |
| Terminated | POC Study in Partially Responsive Generalized Anxiety Disorder NCT02310568 | Pfizer | Phase 2 |
| Completed | Cognitive Training for Mood and Anxiety Disorders NCT02256566 | Icahn School of Medicine at Mount Sinai | N/A |
| Completed | Internet-delivered Treatment for Children With Anxiety Disorders in a Rural Area; an Open Trial in a Clinical NCT02306356 | Karolinska Institutet | N/A |
| Completed | Transdiagnostic iCBT for Depression and Anxiety NCT02266693 | Centre for Addiction and Mental Health | N/A |
| Completed | A Feasibility Study of Group Metacognitive Therapy Versus Mindfulness Meditation Therapy NCT02096484 | University of Manchester | N/A |
| Terminated | Treatment of Pediatric Anxiety Disorders by Predicting Treatment Response Through Biocellular Markers and Slee NCT02189213 | New York State Psychiatric Institute | N/A |
| Terminated | Acoustic Neuromodulation (ANM) for Youth With Anxiety Disorders NCT02572973 | Weill Medical College of Cornell University | N/A |
| Terminated | Transcranial Magnetic Stimulation Treatment for Generalized Anxiety Disorder NCT01815099 | Hartford Hospital | N/A |
| Completed | Psychotherapy for Anxiety in Children With Autism Spectrum Disorder NCT02028247 | University of South Florida | N/A |
| Completed | Brief Behavioral Treatment for Anxiety in Young Children NCT02051192 | University of South Florida | Phase 1 / Phase 2 |
| Completed | GATE: Generalized Anxiety - A Treatment Evaluation NCT01912287 | NYU Langone Health | N/A |
| Terminated | Web-based Attention Bias Modification Treatment for Childhood Anxiety Disorders NCT03764644 | Erasmus Medical Center | N/A |
| Terminated | Attention Bias Modification Treatment for Anxious Youth NCT01979263 | Weill Medical College of Cornell University | N/A |
| Completed | The Effects of Emotional Exposure on State Anxiety NCT03458702 | Texas Tech University | N/A |
| Completed | Testing Beliefs About Uncertainty in the Treatment of Generalized Anxiety Disorder NCT01958788 | Concordia University, Montreal | N/A |
| Completed | Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid Anxiety NCT01919970 | University of South Florida | N/A |
| Unknown | Attention Retraining for Anxiety Disorder Patients Resistent to Antidepressants NCT01906268 | Hospital de Clinicas de Porto Alegre | N/A |
| Completed | Safety, Efficacy and Tolerability of Vilazodone in (GAD) Generalized Anxiety Disorder NCT01844115 | Forest Laboratories | Phase 3 |
| Completed | An Open Label Study of Clinical Utility and Patient Outcomes of the Genecept Assay NCT01507155 | Genomind, LLC | N/A |
| Completed | Safety, Efficacy and Tolerability of Vilazodone in Patients With Generalized Anxiety Disorder NCT01766401 | Forest Laboratories | Phase 3 |
| Completed | Efficacy of SNRI Treatment on Prefrontality in Patients With GAD and Other Comorbities NCT01975480 | START Clinic for Mood and Anxiety Disorders | Phase 4 |
| Completed | Effectiveness of Six Sessions CBT for Adolescents With Emotional Problems in Community Clinics NCT02150265 | University of Tromso | N/A |
| Completed | Calmer Life: Testing the Effectiveness of a Treatment for Anxiety NCT01702220 | Baylor College of Medicine | N/A |
| Completed | Cognitive-Behavioral Treatment and Interpretation Modification Training for Adults With Generalized Anxiety Di NCT01681329 | Concordia University, Montreal | N/A |
| Completed | Locating Regions of Interest in Generalized Anxiety Disorder Using Function Magnetic Resonance Imaging (fMRI) NCT01607710 | Hartford Hospital | — |
| Completed | Safety, Efficacy and Tolerability of Vilazodone in Generalized Anxiety Disorder NCT01629966 | Forest Laboratories | Phase 3 |
| Completed | Transcranial Magnetic Stimulation Treatment for Generalized Anxiety Disorder NCT01659736 | Hartford Hospital | N/A |
| Completed | Computer- Assisted Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disor NCT01565629 | University of South Florida | N/A |
| Completed | Online Treatments for Mood and Anxiety Disorders in Primary Care NCT01482806 | University of Pittsburgh | Phase 2 / Phase 3 |
| Completed | Tandospirone Citrate in the Treatment of Patients With Generalized Anxiety Disorder NCT01614041 | Sumitomo Pharma (Suzhou) Co., Ltd. | Phase 4 |
| Completed | Motivational Interviewing and Cognitive Behavioural Therapy for Generalized Anxiety Disorder NCT01488799 | York University | N/A |
| Completed | Internet-based Treatment of Generalized Anxiety Disorder NCT01570374 | Umeå University | N/A |
| Completed | Treatment Study for Rural Latino Youth With Anxiety NCT01491880 | University of California, San Diego | Phase 1 / Phase 2 |
| Unknown | Combination of Active or Placebo Attentional Bias Modification Treatment (ABMT) to Either Cognitive Behavioral NCT01687764 | Hospital de Clinicas de Porto Alegre | N/A |
| Completed | Computerized Cognitive Behavioral Therapy for Childhood Anxiety in Community Health Centers NCT01416805 | University of South Florida | Phase 3 |
| Completed | Cognitive Behavioral Therapy for Anxiety Disorders in Adolescents With Autism NCT01563003 | University of South Florida | N/A |
| Completed | A Clinical Trial to Study the Effects of Sensoril® for Patients With Generalized Anxiety Disorder NCT01311180 | Natreon, Inc. | Phase 2 |
| Completed | Electronic Self-management Resource Training for Mental Health NCT01304862 | Case Western Reserve University | N/A |
| Completed | Telephone Psychotherapy for Late-Life Generalized Anxiety Disorder (GAD) NCT01259596 | Wake Forest University Health Sciences | N/A |
| Completed | A Study of Duloxetine in Elderly Generalized Anxiety Disorder NCT01118780 | Eli Lilly and Company | Phase 4 |
| Completed | Efficacy of Massage Therapy in the Treatment of Generalized Anxiety Disorder (GAD) NCT01337713 | Emory University | N/A |
| Completed | A Collaborative Care Program to Improve Treatment of Depression and Anxiety Disorders in Cardiac Patients NCT01201967 | Massachusetts General Hospital | Phase 4 |
| Completed | PHARMO Institute Seroquel Safety Study NCT01342120 | AstraZeneca | — |
| Completed | Brain Markers of Anxiety Disorders and SSRI/CBT Treatment in Children and Adolescents NCT01160588 | University of Michigan | — |
| Completed | False Safety Behavior Elimination Therapy: A Randomized Study of a Brief Individual Transdiagnostic Treatment NCT02082561 | Florida State University | N/A |
| Completed | Stress Reduction and Anxiety: Effects on the Function and Structure of the Brain NCT01128309 | Massachusetts General Hospital | N/A |
| Completed | Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders NCT01178385 | University of South Florida | Phase 2 / Phase 3 |
| Completed | Ziprasidone in Bipolar Disorder With Comorbid Lifetime Panic or Generalized Anxiety Disorder(GAD) NCT01172652 | VA Palo Alto Health Care System | Phase 4 |
| Completed | Long Term Chamomile Therapy for Anxiety NCT01072344 | University of Pennsylvania | Phase 3 |
| Terminated | Generalized Anxiety and Seroquel NCT01066143 | Mclean Hospital | N/A |
| Active Not Recruiting | Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals NCT01075672 | Massachusetts General Hospital | N/A |
| Completed | An Open Label Trial of Duloxetine in the Treatment of Irritable Bowel Syndrome and Comorbid Generalized Anxiet NCT00961298 | West Penn Allegheny Health System | Phase 4 |
| Completed | Cognitive Behavioral Therapy (CBT) for Latinos With Generalized Anxiety Disorder in the General Medical Sector NCT01203293 | University of Puerto Rico | Phase 1 |
| Completed | Efficacy of Extended-release Quetiapine (Seroquel XR) as Adjunctive Therapy to Cognitive Behavioral Therapy in NCT01971203 | Icahn School of Medicine at Mount Sinai | N/A |
| Completed | Exercise Training for the Treatment of Generalized Anxiety Disorder NCT00953654 | University of Georgia | N/A |
| Unknown | Mechanisms of Sleep Disturbance in Children With Generalized Anxiety Disorder (GAD) NCT01032473 | Children's National Research Institute | — |
| Completed | Comparing Different CBT Approaches in GAD NCT03650465 | Babes-Bolyai University | N/A |
| Completed | Safety and Efficacy Evaluation Of Pregabalin (Lyrica) With Patients With Generalized Anxiety Disorder NCT00624780 | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Phase 4 |
| Completed | Escitalopram in Patients With Generalized Anxiety Disorder NCT00902564 | H. Lundbeck A/S | Phase 4 |
| Completed | Sleep, Mood, and Behavior Study NCT00787397 | University of Pittsburgh | N/A |
| Terminated | Investigation Of How PD 0332334 And Metformin Are Eliminated From The Body When They Are Administered At The S NCT00809536 | Pfizer | Phase 1 |
| Completed | Psychodynamic Internet Treatment Versus Cognitive Behavioral Therapy (CBT) for Generalized Anxiety Disorder NCT01312116 | Linkoeping University | N/A |
| Terminated | Evaluating The Effects Of Cimetidine On The Elimination Of PD 0332334 From The Body NCT00800280 | Pfizer | Phase 1 |
| Withdrawn | 6-Month Open-Label Safety Study Of PD 0332334 In Elderly Patients With Generalized Anxiety Disorder (GAD) NCT00738738 | Pfizer | Phase 3 |
| Completed | The Comparative Clinical Study of Gamisoyosan on Anxiety of Generalized Anxiety Disorder According to Dosage F NCT01285115 | Korea Health Industry Development Institute | Phase 3 |
| Completed | Duloxetine for the Treatment of Generalized Anxiety Disorder NCT00803361 | Eli Lilly and Company | Phase 3 |
| Completed | Relapse-prevention Study With Lu AA21004 (Vortioxetine) in Patients With Generalized Anxiety Disorder NCT00788034 | H. Lundbeck A/S | Phase 3 |
| Terminated | A 52-Week Open-Label Safety Study of PD 0332334 in Subjects With Generalized Anxiety Disorder (GAD) NCT00735267 | Pfizer | Phase 3 |
| Completed | Transdisciplinary Studies of CBT for Anxiety in Youth: Child Anxiety Treatment Study NCT00774150 | University of Pittsburgh | N/A |
| Completed | Study of the Changes in Metabolic Parameters in Patients Treated With Escitalopram for Six Months NCT00711737 | Changi General Hospital | — |
| Completed | Efficacy and Safety of Vortioxetine (Lu AA21004) for Treatment of Generalized Anxiety Disorder in Adults. NCT00744627 | Takeda | Phase 3 |
| Terminated | Open-Label Pilot Study to Examine the Value of Substituting Quetiapine for Benzodiazepines NCT01244711 | Weill Medical College of Cornell University | Phase 4 |
| Completed | Effectiveness of Cognitive Behavioral Therapy (CBT) for Child Anxiety Disorders in Community Clinics in Norway NCT00735995 | Regionsenter for barn og unges psykiske helse | Phase 2 |
| Completed | Quetiapine in Co-Morbid Depressive and Anxiety Disorders NCT00688818 | Centre for Addiction and Mental Health | N/A |
| Completed | Efficacy of Vortioxetine (Lu AA21004) in Treating Generalized Anxiety Disorder NCT00730691 | Takeda | Phase 3 |
| Completed | Study of Efficacy and Safety of Vortioxetine (Lu AA21004) in Treating Generalized Anxiety Disorder NCT00731120 | Takeda | Phase 3 |
| Terminated | Quetiapine Extended Release (XR) Treatment of Major Depressive Disorder With Comorbid Generalized Anxiety Diso NCT00868374 | Keming Gao | Phase 3 |
| Completed | An Efficacy and Safety Study of Vortioxetine (Lu AA21004) in Treating Generalized Anxiety Disorder NCT00734071 | Takeda | Phase 3 |
| Terminated | A 10-week Study Evaluating the Efficacy and Safety of PD 0332334 for the Treatment of Generalized Anxiety Diso NCT00658762 | Pfizer | Phase 3 |
| Terminated | A 10-week Study Evaluating the Efficacy and Safety of PD 0332334 in Patients With Generalized Anxiety Disorder NCT00658372 | Pfizer | Phase 3 |
| Completed | Cognitive Behavior Treatment of Older Adults With Generalized Anxiety Disorder in Primary Care NCT00765219 | Baylor College of Medicine | N/A |
| Terminated | A 10-week Study Evaluating the Efficacy and Safety of PD 0332334 in Patients With Generalized Anxiety Disorder NCT00658008 | Pfizer | Phase 3 |
| Completed | Drug Treatment Validation of Functional Magnetic Resonance Imaging in Generalized Anxiety Disorder NCT00662259 | University of California, San Diego | Phase 4 |
| Completed | Stress Reduction Techniques and Anxiety: Therapeutic and Neuroendocrine Effects NCT01033851 | Massachusetts General Hospital | Phase 4 |
| Completed | Exploratory Study to Evaluate the Effect of SYN111 (Rufinamide) in Patients With Generalized Anxiety Disorder NCT00595231 | Biotie Therapies Inc. | Phase 2 |
| Completed | Virtual Reality as Anxiety Management Tool for Generalized Anxiety Disorder NCT00602212 | Istituto Auxologico Italiano | N/A |
| Completed | Effectiveness Study of CBT for Anxiety in Children NCT00586586 | Haukeland University Hospital | Phase 2 |
| Completed | rTMS Treatment in Patients With General Anxiety Disorder NCT00616447 | Queen's University | N/A |
| Completed | Generalized Anxiety Disorder Proof of Concept Efficacy and Safety Study of SEP-225441 (Eszopiclone) In GAD Sub NCT00616655 | Sumitomo Pharma America, Inc. | Phase 2 |
| Terminated | Anxiety in Recovering Opiate Dependence NCT00668265 | Beth Israel Medical Center | Phase 4 |
| Completed | Attention Training for Generalized Anxiety Disorder NCT00602563 | San Diego State University | N/A |
| Completed | ERP N1 as a Treatment Predictor of Generalized Anxiety Disorder NCT00613067 | Inje University | N/A |
| Completed | Neural Functioning Underlying Anxiety and Its Treatment (The INSULA Study) NCT00947570 | University of California, San Diego | N/A |
| Completed | Antidepressant Treatment Plus Cognitive Behavioral Therapy for Generalized Anxiety Disorder in Older Adults NCT00601965 | Veterans Medical Research Foundation | N/A |
| Completed | A 10-Week Study Evaluating the Efficacy And Safety of PD 0332334 for the Treatment of Generalized Anxiety Diso NCT00542685 | Pfizer | Phase 3 |
| Completed | An Open-label Study to Investigate the Absorption, Metabolism and Excretion of Radiolabeled PD 0332334 in Six NCT00537615 | Pfizer | Phase 1 |
| Completed | Therapeutic Massage for Generalized Anxiety Disorder NCT00515242 | Kaiser Permanente | Phase 1 / Phase 2 |
| Completed | Evaluating the Effects of Stress in Pregnancy NCT00525226 | Emory University | — |
| Completed | Study of Pexacerfont (BMS-562086) in the Treatment of Outpatients With Generalized Anxiety Disorder NCT00481325 | Bristol-Myers Squibb | Phase 2 / Phase 3 |
| Unknown | Brain Imaging and Computer Games in Children With Either Bipolar Disorder, ADHD, Anxiety or Healthy Controls NCT01570426 | Bradley Hospital | — |
| Completed | Quetiapine SR and Divalproex Sodium ER in the Treatment of Anxiety in Bipolar Disorder With Panic Disorder and NCT00579280 | University of South Florida | Phase 4 |
| Completed | CBT for GAD: Impact of Cognitive Processing on Treatment Outcome NCT03099772 | Concordia University, Montreal | N/A |
| Completed | RCT of an Acceptance-based Behavior Therapy for GAD NCT00961493 | University of Massachusetts, Boston | N/A |
| Completed | Comparing Cognitive Behaviour Therapy (CBT) With Metacognitive Therapy (MCT) in the Treatment of GAD NCT00426426 | Norwegian University of Science and Technology | N/A |
| Completed | Pregabalin in the Treatment of Patients With Generalized Anxiety Disorder (GAD). NCT00413010 | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Phase 3 |
| Completed | Combined Treatment for Generalized Anxiety Disorder (GAD) NCT00620776 | University of Pennsylvania | Phase 2 |
| Completed | Efficacy and Safety of Pregabalin vs Placebo for Generalized Anxiety Disorder (GAD) Symptoms in Subjects Disco NCT00368745 | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Phase 3 |
| Completed | Repetitive Magnetic Transcranial Stimulation (rTMS) in the Treatment of Generalized Anxiety Disorder (GAD) NCT00662584 | University of California, Los Angeles | Phase 3 |
| Completed | Primary Care Intervention Strategy for Anxiety Disorders NCT00347269 | University of Washington | Phase 4 |
| Completed | Efficacy of Treatment for Generalized Anxiety Disorder NCT00456742 | University of British Columbia | — |
| Completed | Efficacy and Safety Study of Seroquel SR in the Treatment of Generalized Anxiety Disorder NCT00322595 | AstraZeneca | Phase 3 |
| Completed | Safety & Efficacy Study of Quetiapine Fumarate (SEROQUEL®) vs. Placebo in Generalized Anxiety Disorder NCT00329264 | AstraZeneca | Phase 3 |
| Completed | Safety & Efficacy Study of Quetiapine Fumarate (SEROQUEL®) vs. Placebo & Active Control in Generalized Anxiety NCT00329446 | AstraZeneca | Phase 3 |
| Completed | Acamprosate in Alcoholics With Comorbid Anxiety or Depression NCT00330174 | Medical University of South Carolina | Phase 4 |
| Completed | Treatment of Late-life Anxiety in Primary Care Settings NCT00938093 | Wake Forest University Health Sciences | N/A |
| Terminated | Ziprasidone for the Treatment of Generalized Anxiety in Patients With Bipolar Disorder NCT00374543 | Massachusetts General Hospital | Phase 4 |
| Completed | Trial of Seroquel SR for Alcohol Dependence and Comorbid Anxiety NCT00352469 | Creighton University | Phase 4 |
| Completed | A 5-Week Trial Of PD 0332334 And Alprazolam Extended Release Compared To Placebo In Patients With Generalized NCT00921063 | Pfizer | Phase 2 |
| Completed | Chamomile Therapy for Generalized Anxiety NCT00645983 | University of Pennsylvania | Phase 4 |
| Completed | Trial to Compare Time to Response in the Symptoms of Anxiety to Concomitant Treatment With Niravam™ and an SSR NCT00266409 | UCB Pharma | Phase 4 |
| Completed | Pharmacological Treatment of Generalized Anxiety Disorder in the Elderly NCT00701675 | VA Office of Research and Development | Phase 4 |
| Completed | A Pilot Study of Cranial Electrotherapy Stimulation[CES] for Generalized Anxiety Disorder NCT00539357 | University of California, Los Angeles | Phase 4 |
| Completed | Black Cohosh as Alternative Therapy for Treating Menopause-Related Anxiety NCT00120458 | University of Pennsylvania | Phase 4 |
| Completed | Safety and Efficacy of Eszopiclone in Patients With Generalized Anxiety Disorder NCT00235508 | Sumitomo Pharma America, Inc. | Phase 4 |
| Completed | Memantine Treatment for Obsessive-compulsive Disorder and Generalized Anxiety Disorder NCT00674219 | University of California, Los Angeles | Phase 3 |
| Completed | Aripiprazole for the Treatment of Refractory Anxiety NCT00438386 | Massachusetts General Hospital | Phase 4 |
| Completed | Cognitive-Behavioral Therapy and Escitalopram for Generalized Anxiety Disorder(GAD) NCT00219349 | New York State Psychiatric Institute | Phase 4 |
| Completed | Drug Therapy for Generalized Anxiety Disorder Among the Elderly NCT00105586 | University of Pittsburgh | Phase 4 |
| Completed | A 10-Week Efficacy and Safety Study for of Gabitril in the Treatment of Adults With Generalized Anxiety Disord NCT00236054 | Cephalon | Phase 3 |
| Completed | A 10-Week Study for Efficacy and Safety Study of Gabitril in the Treatment of Adults With Generalized Anxiety NCT00236067 | Cephalon | Phase 3 |
| Completed | Treating Late-Life Generalized Anxiety Disorder (GAD) in Primary Care NCT00308724 | Baylor College of Medicine | N/A |