NCT00616447

rTMS Treatment in Patients With General Anxiety Disorder

A 12-week, Double-blind, Randomized, Placebo-controlled Multicentered Study Evaluating Efficacy and Safety of High-frequency Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment in Patients With Generalized Anxiety Disorder (GAD)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Queen's University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This study will compare the change detected by a standardized rating scale (Hamilton Anxiety Rating Scale) scores in the active treatment group as compared to sham (placebo) group after 6 weeks of rTMS treatments. It is hoped that 6 weeks of rTMS treatment will lead to improvement of core symptoms in patients with GAD.

Conditions

• Generalized Anxiety Disorder

Interventions

Type	Name	Description
DEVICE	Repetitive transcranial magnetic stimulation	6 weeks of repetitive transcranial magnetic stimulation . Treatment comprises of stimulation with rTMS frequency 20Hz, intensity 110% of MT, 20 trains, 9 sec/train, 51 sec ITI applied over right dorsolateral prefrontal cortex by a figure eight shaped coil. Treatment will be given 5 times a week for 4 weeks, 3 times a week during Week 5 and 2 times a week during Week 6.
DEVICE	placebo sham	Sham treatment will mimic active treatment mentioned above.

Timeline

• Start date: 2008-01-01
• Primary completion: 2012-11-01
• Completion: 2012-11-01
• First posted: 2008-02-15
• Last updated: 2015-12-16

Locations

2 sites across 2 countries: Bulgaria, Canada