Clinical Trials Directory

Trials / Terminated

TerminatedNCT03463018

Echinacea Angustifolia (AnxioCalm) in Anxiety

A Phase 2 Randomized, Double-Blind, Parallel-Group, Placebo Controlled Fixed-Dose Study of Echinacea Angustifoliae Root Extract (AnxioCalm) in Healthy Subjects With Subthreshold Symptoms of Anxiety

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
100 (actual)
Sponsor
EuroPharma, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study evaluates whether Echinacea angustifolia (AnxioCalm) is a safe and effective treatment for mild to moderate Generalized Anxiety Disorder (GAD) symptoms. Half the participants will receive Echinacea angustifolia and half will receive placebo.

Detailed description

Echinacea angustifolia root extract (AnxioCalm), standardized for the content of echinacoside and its alkamide profile, is intended to be used for 'amelioration of sub-threshold and mild anxiety which are risk factors in the development of Generalized Anxiety Disorder (GAD) and depression' in symptomatic people 'who are not eligible for anxiolytic medication.' Existing medical interventions, which require long periods of repeated administration, have significant safety concerns.

Conditions

Interventions

TypeNameDescription
DIETARY_SUPPLEMENTEchinacea angustifolia20 mg tablet of Echinacea angustifolia, standardized for echinacoside (not less than 3%) and alkamides (not less than 0.8%)
DIETARY_SUPPLEMENTPlaceboPlacebo tablet containing matching excipients to the active intervention

Timeline

Start date
2018-06-06
Primary completion
2020-10-03
Completion
2021-12-15
First posted
2018-03-13
Last updated
2022-03-24

Locations

1 site across 1 country: Georgia

Source: ClinicalTrials.gov record NCT03463018. Inclusion in this directory is not an endorsement.